Motif ID: POU5F1.p2

Z-value: 1.365


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_312425930.341.9e-01Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_64922420 2.735 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr12_+_14409875 2.588 NM_018179
ATF7IP
activating transcription factor 7 interacting protein
chrX_-_33267646 2.527 NM_000109
DMD
dystrophin
chr3_-_64186151 2.463 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr13_-_101852028 1.965 NM_175929
FGF14
fibroblast growth factor 14
chr10_+_68355797 1.753 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr7_-_76667045 1.668 NM_006682
FGL2
fibrinogen-like 2
chr5_+_54491702 1.665 NM_001008397
GPX8
glutathione peroxidase 8 (putative)
chr13_-_85271329 1.644 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr1_+_161305188 1.470 NM_005613
RGS4
regulator of G-protein signaling 4
chr12_-_48902692 1.432 NM_001113547
LIMA1
LIM domain and actin binding 1
chr1_+_161305558 1.410 NM_001113381
RGS4
regulator of G-protein signaling 4
chr16_-_3783475 1.391 CREBBP
CREB binding protein
chr18_-_45271938 1.383 RPL17-C18ORF32
RPL17
RPL17-C18orf32 read-through transcript
ribosomal protein L17
chrX_+_135397790 1.352 NM_001727
BRS3
bombesin-like receptor 3
chr19_-_54835162 1.311 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr6_-_26151863 1.304 NM_021062
HIST1H2BB
histone cluster 1, H2bb
chr1_-_215329569 1.291 NM_206594
NM_206595
ESRRG

estrogen-related receptor gamma

chr1_+_81544432 1.169 LPHN2
latrophilin 2
chr3_-_58175437 1.158 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr11_+_111551417 1.116 NM_031938
BCO2
beta-carotene oxygenase 2
chr3_+_142175329 1.092 SLC25A36
solute carrier family 25, member 36
chr2_+_102456193 1.062 NM_001011552
SLC9A4
solute carrier family 9 (sodium/hydrogen exchanger), member 4
chrX_+_14457340 1.041 NM_001118885
NM_001118886
NM_001171942
NM_002063
GLRA2



glycine receptor, alpha 2



chr17_-_8004671 1.022 VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr4_-_139382672 0.995 NM_014331
SLC7A11
solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
chr9_-_116920232 0.949 NM_002160
TNC
tenascin C
chr12_+_52653176 0.947 NM_014212
HOXC11
homeobox C11
chr10_-_98021144 0.941 NM_001114094
NM_013314
BLNK

B-cell linker

chr14_+_64077171 0.934 HSPA2
heat shock 70kDa protein 2
chr20_+_19863716 0.907 RIN2
Ras and Rab interactor 2
chr1_+_161305019 0.907 NM_001102445
RGS4
regulator of G-protein signaling 4
chr5_-_64813459 0.894 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr10_-_62002672 0.885 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr3_+_29297806 0.878 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr3_+_129124591 0.874 NM_207335
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr1_-_151296611 0.865 NM_005988
SPRR2A
small proline-rich protein 2A
chr7_-_50103335 0.865 NM_001159878
NM_007009
ZPBP

zona pellucida binding protein

chr7_-_104696678 0.863 NM_182691
SRPK2
SRSF protein kinase 2
chr15_-_81037554 0.857 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr4_+_81325447 0.855 NM_020226
PRDM8
PR domain containing 8
chr12_-_14024187 0.852 NM_000834
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr6_+_131613196 0.850 NM_004842
NM_138633
AKAP7

A kinase (PRKA) anchor protein 7

chr5_-_177950161 0.842 NM_173465
COL23A1
collagen, type XXIII, alpha 1
chr7_+_113853790 0.841 NM_001172767
NM_148899
FOXP2

forkhead box P2

chr15_-_40537002 0.834 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr7_+_111908143 0.834 NM_001134468
NM_182597
C7orf53

chromosome 7 open reading frame 53

chr18_+_40514772 0.832 NM_015559
SETBP1
SET binding protein 1
chr5_-_124108672 0.813 NM_020747
ZNF608
zinc finger protein 608
chr13_-_76358370 0.811 KCTD12
potassium channel tetramerisation domain containing 12
chr4_-_153493133 0.795 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr1_-_118529303 0.789 NM_206996
SPAG17
sperm associated antigen 17
chr18_+_40513889 0.787 NM_001130110
SETBP1
SET binding protein 1
chr16_+_10878539 0.782 NM_000246
CIITA
class II, major histocompatibility complex, transactivator
chr4_+_90252990 0.779 NM_145715
TIGD2
tigger transposable element derived 2
chr9_-_85773899 0.770 HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr1_-_148126089 0.766 NM_175065
HIST2H2AB
HIST2H2BE
histone cluster 2, H2ab
histone cluster 2, H2be
chr1_-_42156957 0.758 HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr10_-_93992982 0.757 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr17_-_44047299 0.747 NM_024016
HOXB8
homeobox B8
chr4_-_110443247 0.736 NM_032518
NM_198721
COL25A1

collagen, type XXV, alpha 1

chr12_-_16649211 0.732 LMO3
LIM domain only 3 (rhombotin-like 2)
chr14_+_78815406 0.732 NM_001105250
NM_138970
NRXN3

neurexin 3

chr14_-_98807574 0.711 NM_022898
NM_138576
BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein)

chr1_-_148050534 0.704 NM_001024599
NM_001161334
HIST2H2BF

histone cluster 2, H2bf

chrX_+_16051344 0.704 NM_005314
GRPR
gastrin-releasing peptide receptor
chr2_+_17861266 0.700 NM_001105569
MSGN1
mesogenin 1
chr13_+_48582389 0.688 NM_014923
FNDC3A
fibronectin type III domain containing 3A
chr7_-_41709191 0.686 NM_002192
INHBA
inhibin, beta A
chr11_+_65027721 0.683


chr1_-_42157077 0.681 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chrX_-_31436335 0.677 NM_004014
DMD
dystrophin
chr6_+_53043729 0.674 NM_012347
FBXO9
F-box protein 9
chr17_-_38529638 0.672 NM_007298
BRCA1
breast cancer 1, early onset
chrX_+_80344253 0.672 SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr2_-_227371698 0.667 NM_005544
IRS1
insulin receptor substrate 1
chr1_-_197173159 0.664 LOC100131234
familial acute myelogenous leukemia related factor
chr8_-_28403652 0.661 NM_172366
FBXO16
ZNF395
F-box protein 16
zinc finger protein 395
chr15_+_81907176 0.659 SH3GL3
SH3-domain GRB2-like 3
chr3_+_48239865 0.653 NM_004345
CAMP
cathelicidin antimicrobial peptide
chr16_+_81218142 0.651 CDH13
cadherin 13, H-cadherin (heart)
chr10_-_123346148 0.646 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr2_-_113310796 0.640 NM_000576
IL1B
interleukin 1, beta
chr15_+_81906983 0.635 NM_003027
SH3GL3
SH3-domain GRB2-like 3
chr11_-_94603857 0.632 NM_144665
SESN3
sestrin 3
chr9_+_122923864 0.631 CEP110
centrosomal protein 110kDa
chr10_+_91051685 0.630 NM_001547
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chrX_-_123925343 0.628 NM_001163278
NM_001163279
NM_014253
ODZ1


odz, odd Oz/ten-m homolog 1(Drosophila)


chr1_-_108308997 0.625 NM_006113
VAV3
vav 3 guanine nucleotide exchange factor
chr10_-_116276651 0.621 NM_006720
ABLIM1
actin binding LIM protein 1
chr18_+_75968133 0.620 ADNP2
ADNP homeobox 2
chrX_-_62891066 0.611 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr2_+_237143118 0.611 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr2_+_173794692 0.611 ZAK
sterile alpha motif and leucine zipper containing kinase AZK
chr5_+_49998528 0.609 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr11_+_69176391 0.599 CCND1
cyclin D1
chr2_-_218739891 0.597 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr11_-_34336102 0.595 NM_145804
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr5_+_49998677 0.588 PARP8
poly (ADP-ribose) polymerase family, member 8
chr14_-_93512818 0.585 ASB2
ankyrin repeat and SOCS box containing 2
chr4_+_41395493 0.585 LIMCH1
LIM and calponin homology domains 1
chr5_-_73973004 0.585 NM_003633
ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr22_-_44828636 0.584 NM_018280
C22orf26
chromosome 22 open reading frame 26
chr4_+_120276386 0.581 NM_016599
MYOZ2
myozenin 2
chr3_+_51837608 0.578 NM_001085479
IQCF3
IQ motif containing F3
chr10_+_95838801 0.575 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr8_+_11703368 0.575 FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr21_-_35174742 0.573 RUNX1
runt-related transcription factor 1
chr3_+_42107711 0.571 NM_001042646
TRAK1
trafficking protein, kinesin binding 1
chr3_-_102194938 0.567 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr13_-_59223074 0.566


chr22_-_26527469 0.566 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr16_+_81218074 0.558 NM_001257
CDH13
cadherin 13, H-cadherin (heart)
chr13_-_98428244 0.557 NM_001130048
NM_001130050
DOCK9

dedicator of cytokinesis 9

chr7_-_83662152 0.552 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr11_-_114880275 0.548 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chrX_+_80344215 0.546 SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr4_+_76700281 0.533 NM_178497
C4orf26
chromosome 4 open reading frame 26
chr17_-_2250967 0.524 NM_020310
MNT
MAX binding protein
chr1_-_205012348 0.523 NM_000572
IL10
interleukin 10
chr2_+_5750229 0.521 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr6_-_119512035 0.520 NM_001100411
FAM184A
family with sequence similarity 184, member A
chr1_-_151280201 0.519 NM_006945
SPRR2D
small proline-rich protein 2D
chr11_+_10434056 0.518 NM_001025390
AMPD3
adenosine monophosphate deaminase 3
chr7_+_93862137 0.516 COL1A2
PLAG1
collagen, type I, alpha 2
pleiomorphic adenoma gene 1
chr4_-_159313613 0.511 NM_001031700
NM_001128424
FAM198B

family with sequence similarity 198, member B

chr2_-_165768798 0.508 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chr12_+_111829121 0.507 NM_001032409
NM_002534
NM_016816
OAS1


2',5'-oligoadenylate synthetase 1, 40/46kDa


chr4_-_41579325 0.506


chr2_-_210726539 0.504 C2orf67
chromosome 2 open reading frame 67
chr8_-_72437020 0.504 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr6_-_10523424 0.503 NM_003220
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr1_+_208008517 0.501 TRAF3IP3
TRAF3 interacting protein 3
chr7_-_27149750 0.500 NM_019102
HOXA5
homeobox A5
chr17_-_78391178 0.498 NM_024702
ZNF750
zinc finger protein 750
chr14_-_74669864 0.497 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr17_-_45427565 0.493 NM_005220
DLX3
distal-less homeobox 3
chr6_-_134540666 0.492 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr18_+_30544193 0.491 NM_001198941
NM_032978
DTNA

dystrobrevin, alpha

chr6_-_130224108 0.489 NM_001010876
C6orf191
chromosome 6 open reading frame 191
chr2_+_165804157 0.489 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr7_+_28418668 0.488 NM_182898
CREB5
cAMP responsive element binding protein 5
chr8_-_25958556 0.488 EBF2
early B-cell factor 2
chrX_-_106846924 0.486 NM_004089
TSC22D3
TSC22 domain family, member 3
chr1_-_147665783 0.486 HIST2H2BF
histone cluster 2, H2bf
chr4_+_124540114 0.483 NM_005841
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr3_-_129023850 0.476 NM_007283
MGLL
monoglyceride lipase
chr22_+_36422940 0.476 NM_001039141
TRIOBP
TRIO and F-actin binding protein
chr4_-_159313167 0.474 NM_016613
FAM198B
family with sequence similarity 198, member B
chr9_+_35722490 0.471 CREB3
cAMP responsive element binding protein 3
chr3_-_87122958 0.469 VGLL3
vestigial like 3 (Drosophila)
chr3_+_145174856 0.469 NM_001134470
C3orf58
chromosome 3 open reading frame 58
chr1_+_27541086 0.469 SYTL1
synaptotagmin-like 1
chr21_-_31123797 0.466 NM_181606
KRTAP7-1
keratin associated protein 7-1 (gene/pseudogene)
chr2_+_65517316 0.466 FLJ16124
FLJ16124 protein
chr5_-_172976212 0.465 BOD1
biorientation of chromosomes in cell division 1
chrX_-_80344096 0.465 NM_030763
HMGN5
high-mobility group nucleosome binding domain 5
chr1_+_172683834 0.461 NM_005684
GPR52
G protein-coupled receptor 52
chrX_-_24575375 0.456 NM_001163265
NM_004845
PCYT1B

phosphate cytidylyltransferase 1, choline, beta

chr12_-_11066436 0.456 NM_176888
TAS2R19
taste receptor, type 2, member 19
chr11_+_34599227 0.452 EHF
ets homologous factor
chr13_-_32757835 0.451 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr12_+_52713098 0.451 NM_018953
HOXC5
homeobox C5
chr1_-_211087570 0.450 NM_001024601
C1orf227
chromosome 1 open reading frame 227
chr5_-_172976196 0.450 BOD1
biorientation of chromosomes in cell division 1
chr6_-_10523203 0.449 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr18_-_51406841 0.449 NM_001083962
NM_003199
TCF4

transcription factor 4

chr4_-_159312973 0.448 FAM198B
family with sequence similarity 198, member B
chr1_+_15145001 0.447 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr11_-_111539881 0.447 NM_001562
IL18
interleukin 18 (interferon-gamma-inducing factor)
chr8_-_119192985 0.446 NM_000127
EXT1
exostosin 1
chr8_-_15140162 0.444 NM_139167
SGCZ
sarcoglycan, zeta
chr2_-_40593074 0.442 NM_001112802
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr1_+_168381811 0.442 NM_001136107
METTL11B
methyltransferase like 11B
chr12_-_13139848 0.441 NM_031289
NM_153823
GSG1

germ cell associated 1

chr11_-_119513429 0.440 TRIM29
tripartite motif containing 29
chrX_-_106846684 0.440 TSC22D3
TSC22 domain family, member 3
chr10_-_64698831 0.436 NM_004241
JMJD1C
jumonji domain containing 1C
chr5_-_172976259 0.433 NM_001159651
NM_138369
BOD1

biorientation of chromosomes in cell division 1

chr6_+_26381122 0.431 NM_003525
HIST1H2BI
histone cluster 1, H2bi
chr6_+_35812836 0.430 NM_145028
C6orf81
chromosome 6 open reading frame 81
chr6_-_32892705 0.429 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chrX_+_28515479 0.428 NM_014271
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr2_+_143351536 0.424 NM_001032998
NM_003937
KYNU

kynureninase

chr4_-_100575313 0.423 NM_001166504
NM_000673
ADH7

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

chr11_+_34599163 0.423 NM_012153
EHF
ets homologous factor
chr15_+_62578671 0.422 NM_015042
ZNF609
zinc finger protein 609
chr9_+_108665168 0.419 NM_021224
ZNF462
zinc finger protein 462
chr14_+_64076916 0.418 NM_021979
HSPA2
heat shock 70kDa protein 2
chr12_-_49897743 0.414 POU6F1
POU class 6 homeobox 1
chr3_-_9266251 0.414 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr4_-_47534815 0.411 NM_006587
CORIN
corin, serine peptidase
chr1_-_151310707 0.410 NM_001017418
SPRR2B
small proline-rich protein 2B
chr17_+_38306339 0.410 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chrX_-_109570113 0.408 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr6_-_42527760 0.408 NM_033502
TRERF1
transcriptional regulating factor 1
chr1_+_200246312 0.406 NM_001114309
NM_004433
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr8_+_123863169 0.406 ZHX2
zinc fingers and homeoboxes 2
chr8_-_93181091 0.406 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_+_104986009 0.406 NM_000829
NM_001077243
NM_001077244
GRIA4


glutamate receptor, ionotrophic, AMPA 4



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.42 2.14e-07 GO:0051252 regulation of RNA metabolic process
1.30 2.61e-07 GO:0032502 developmental process
1.42 3.22e-07 GO:0006355 regulation of transcription, DNA-dependent
1.31 5.69e-07 GO:0007275 multicellular organismal development
1.19 6.12e-07 GO:0050794 regulation of cellular process
1.38 6.41e-07 GO:0010468 regulation of gene expression
1.35 6.42e-07 GO:0048731 system development
1.39 6.64e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.23 7.44e-07 GO:0032501 multicellular organismal process
1.64 1.52e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.32 2.06e-06 GO:0048856 anatomical structure development
1.31 2.44e-06 GO:0060255 regulation of macromolecule metabolic process
1.30 2.94e-06 GO:0080090 regulation of primary metabolic process
1.36 5.45e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.16 1.58e-05 GO:0050789 regulation of biological process
1.33 1.69e-05 GO:0031326 regulation of cellular biosynthetic process
1.33 2.65e-05 GO:0009889 regulation of biosynthetic process
1.15 4.68e-05 GO:0065007 biological regulation
1.39 7.29e-05 GO:0048513 organ development
1.36 7.49e-05 GO:0048523 negative regulation of cellular process
1.27 7.52e-05 GO:0031323 regulation of cellular metabolic process
1.79 1.08e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.77 1.41e-04 GO:0051253 negative regulation of RNA metabolic process
1.31 1.71e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.71 2.06e-04 GO:0045893 positive regulation of transcription, DNA-dependent
1.44 2.16e-04 GO:0007399 nervous system development
1.67 2.52e-04 GO:0010628 positive regulation of gene expression
1.30 2.86e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.65 6.06e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.31 1.15e-03 GO:0048519 negative regulation of biological process
1.29 1.27e-03 GO:0048518 positive regulation of biological process
1.61 1.71e-03 GO:0009890 negative regulation of biosynthetic process
1.64 1.72e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.65 1.75e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.66 1.83e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59 1.84e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.44 1.87e-03 GO:0009893 positive regulation of metabolic process
1.66 1.92e-03 GO:0010629 negative regulation of gene expression
1.33 2.18e-03 GO:0030154 cell differentiation
1.22 3.30e-03 GO:0019222 regulation of metabolic process
1.73 3.50e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.45 3.70e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.53 3.82e-03 GO:0009888 tissue development
1.62 4.47e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.43 5.36e-03 GO:0031325 positive regulation of cellular metabolic process
1.59 5.97e-03 GO:0051254 positive regulation of RNA metabolic process
1.31 6.75e-03 GO:0048869 cellular developmental process
3.24 6.94e-03 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
1.51 8.25e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.28 8.39e-03 GO:0048522 positive regulation of cellular process
1.50 1.15e-02 GO:0009891 positive regulation of biosynthetic process
1.53 1.31e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.77 1.46e-02 GO:0009792 embryo development ending in birth or egg hatching
1.51 1.85e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.70 1.89e-02 GO:0032583 regulation of gene-specific transcription
1.77 1.99e-02 GO:0043009 chordate embryonic development
1.97 2.17e-02 GO:0003002 regionalization
1.73 2.22e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.25 2.50e-02 GO:0071842 cellular component organization at cellular level
1.53 3.09e-02 GO:0009790 embryo development
1.74 3.52e-02 GO:0060429 epithelium development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 3.80e-04 GO:0005634 nucleus
1.55 5.69e-03 GO:0030054 cell junction
1.16 4.40e-02 GO:0005886 plasma membrane
1.16 4.47e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.66 2.97e-08 GO:0001071 nucleic acid binding transcription factor activity
1.66 2.97e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
1.40 4.00e-08 GO:0003677 DNA binding
1.69 8.67e-06 GO:0043565 sequence-specific DNA binding
1.27 2.24e-05 GO:0003676 nucleic acid binding
1.54 2.44e-05 GO:0030528 transcription regulator activity
3.43 1.13e-03 GO:0003707 steroid hormone receptor activity
3.24 2.90e-03 GO:0004879 ligand-dependent nuclear receptor activity
1.27 1.75e-02 GO:0008270 zinc ion binding