Motif ID: PPARG.p2

Z-value: 0.853


Transcription factors associated with PPARG.p2:

Gene SymbolEntrez IDGene Name
PPARG 5468 peroxisome proliferator-activated receptor gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PPARGchr3_+_12367993-0.476.4e-02Click!


Activity profile for motif PPARG.p2.

activity profile for motif PPARG.p2


Sorted Z-values histogram for motif PPARG.p2

Sorted Z-values for motif PPARG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PPARG.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_54361216 3.053 TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr7_-_100262971 1.454 NM_004444
EPHB4
EPH receptor B4
chr8_-_27906287 1.043 NM_173833
SCARA5
scavenger receptor class A, member 5 (putative)
chr22_+_21094094 1.004


chr19_+_18312365 0.944 NM_017712
FKBP8
PGPEP1
FK506 binding protein 8, 38kDa
pyroglutamyl-peptidase I
chr3_-_110319598 0.899 NM_014429
MORC1
MORC family CW-type zinc finger 1
chr19_-_60432443 0.852 NM_173804
TMEM86B
transmembrane protein 86B
chr13_+_48692472 0.787 NM_001507
MLNR
motilin receptor
chr1_-_3806683 0.735 NM_207356
C1orf174
chromosome 1 open reading frame 174
chr22_-_21814208 0.654 NM_014433
RTDR1
rhabdoid tumor deletion region gene 1
chr1_-_150029529 0.618 NM_001083963
NM_001083964
NM_001083965
NM_006862
TDRKH



tudor and KH domain containing



chr1_+_45542138 0.599 LOC400752
hypothetical LOC400752
chr1_-_3806564 0.568 C1orf174
chromosome 1 open reading frame 174
chr22_+_21042091 0.560 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr22_+_21006814 0.545


chr6_-_31736488 0.507 NM_021184
C6orf47
chromosome 6 open reading frame 47
chr14_+_23855291 0.495 LTB4R
leukotriene B4 receptor
chr2_+_218992053 0.451 NM_007127
VIL1
villin 1
chr19_-_55708936 0.440 NM_001114598
ASPDH
aspartate dehydrogenase domain containing
chr9_+_130428519 0.428 SPTAN1
spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chr22_+_21484240 0.425


chr7_-_99365178 0.396 NM_181538
GJC3
gap junction protein, gamma 3, 30.2kDa
chr11_+_46697312 0.392 NM_000506
F2
coagulation factor II (thrombin)
chr8_-_145613034 0.386 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr8_-_145613058 0.385 NM_130849
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr6_-_28999388 0.382 TRIM27
tripartite motif containing 27
chr14_+_23700261 0.364 NM_006084
IRF9
interferon regulatory factor 9
chr20_-_62081434 0.359 NM_080621
SAMD10
sterile alpha motif domain containing 10
chr10_+_114126004 0.359 ACSL5
acyl-CoA synthetase long-chain family member 5
chr17_-_39340414 0.334 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr1_+_205992004 0.331 NM_002389
NM_153826
NM_172350
NM_172351
NM_172352
NM_172353
NM_172359
NM_172361
CD46







CD46 molecule, complement regulatory protein







chr2_-_89223666 0.331 IGKC
IGK@
immunoglobulin kappa constant
immunoglobulin kappa locus
chr15_-_72540484 0.330 UBL7
ubiquitin-like 7 (bone marrow stromal cell-derived)
chr11_+_46697335 0.329 F2
coagulation factor II (thrombin)
chr8_-_107851593 0.326 NM_139166
ABRA
actin-binding Rho activating protein
chr14_+_105024301 0.318 NM_001311
CRIP1
cysteine-rich protein 1 (intestinal)
chr17_+_39603599 0.318 NM_080863
ASB16
ankyrin repeat and SOCS box containing 16
chr15_-_72540518 0.310 UBL7
ubiquitin-like 7 (bone marrow stromal cell-derived)
chr15_-_72540543 0.309 NM_032907
NM_201265
UBL7

ubiquitin-like 7 (bone marrow stromal cell-derived)

chr6_-_117193505 0.305 NM_001085480
FAM162B
family with sequence similarity 162, member B
chr11_+_303852 0.300 NM_003641
IFITM1
interferon induced transmembrane protein 1 (9-27)
chr22_+_21559959 0.298 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr16_+_84204424 0.297 NM_014615
KIAA0182
KIAA0182
chr11_+_298106 0.295 NM_006435
IFITM2
interferon induced transmembrane protein 2 (1-8D)
chr12_+_108399829 0.279 UBE3B
ubiquitin protein ligase E3B
chr14_-_105524207 0.276 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_+_26389638 0.276 NM_198137
CATSPER4
cation channel, sperm associated 4
chr12_+_108399842 0.276 UBE3B
ubiquitin protein ligase E3B
chr3_+_8750485 0.273 NM_033337
NM_001234
CAV3

caveolin 3

chr3_+_33815097 0.273 PDCD6IP
programmed cell death 6 interacting protein
chr15_+_72540655 0.271 LOC440288
similar to FLJ16518 protein
chr10_+_114125927 0.271 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr1_+_201541241 0.268 BTG2
BTG family, member 2
chr12_+_108399844 0.267 UBE3B
ubiquitin protein ligase E3B
chr1_+_559618 0.265


chr11_+_46697345 0.262 F2
coagulation factor II (thrombin)
chr19_-_5790702 0.258 NM_000150
NM_001040701
FUT6

fucosyltransferase 6 (alpha (1,3) fucosyltransferase)

chr1_-_149955870 0.257 NM_007185
CELF3
CUGBP, Elav-like family member 3
chr3_+_33815081 0.253 PDCD6IP
programmed cell death 6 interacting protein
chr22_+_20880159 0.253 IGLV6-57
immunoglobulin lambda variable 6-57
chr9_-_33437527 0.252 NM_004925
AQP3
aquaporin 3 (Gill blood group)
chr7_-_128330615 0.248 KCP
kielin/chordin-like protein
chr16_+_1143241 0.246 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr1_+_205992032 0.245 CD46
CD46 molecule, complement regulatory protein
chr8_-_145672525 0.245 NM_003923
FOXH1
forkhead box H1
chr5_-_179951071 0.244 NM_052863
SCGB3A1
secretoglobin, family 3A, member 1
chr1_-_6341553 0.242 NM_181866
ACOT7
acyl-CoA thioesterase 7
chr19_+_951295 0.241 NM_138690
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr7_+_128367961 0.238 NM_001098627
IRF5
interferon regulatory factor 5
chr1_+_201541269 0.237 NM_006763
BTG2
BTG family, member 2
chr10_+_114125955 0.229 ACSL5
acyl-CoA synthetase long-chain family member 5
chr19_-_14447163 0.226 NM_000955
PTGER1
prostaglandin E receptor 1 (subtype EP1), 42kDa
chr17_+_16259573 0.223 NM_016113
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr12_+_108399813 0.219 NM_130466
NM_183415
UBE3B

ubiquitin protein ligase E3B

chr3_+_33815064 0.218 NM_001162429
NM_013374
PDCD6IP

programmed cell death 6 interacting protein

chr19_-_54636425 0.216 NM_020309
SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr3_+_170974745 0.212 NM_001185119
MYNN
myoneurin
chr19_-_54618410 0.210 NM_178449
PTH2
parathyroid hormone 2
chr22_+_18388602 0.206 NM_152906
C22orf25
chromosome 22 open reading frame 25
chr3_+_33815127 0.202 PDCD6IP
programmed cell death 6 interacting protein
chr11_+_2880135 0.195 SLC22A18
solute carrier family 22, member 18
chr8_+_145692916 0.194 NM_032902
PPP1R16A
protein phosphatase 1, regulatory (inhibitor) subunit 16A
chr13_+_36146048 0.183 NM_203451
C13orf36
chromosome 13 open reading frame 36
chr7_+_150390566 0.182 SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr22_+_21011653 0.181


chr22_+_20880112 0.181


chr22_+_18388633 0.180 C22orf25
chromosome 22 open reading frame 25
chr11_-_63689780 0.177 MACROD1
MACRO domain containing 1
chr7_+_1543644 0.176 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr7_-_44165398 0.174 NM_033507
NM_033508
GCK

glucokinase (hexokinase 4)

chr11_+_2880104 0.162 SLC22A18
solute carrier family 22, member 18
chr3_+_38512850 0.155 EXOG
endo/exonuclease (5'-3'), endonuclease G-like
chr8_+_144888275 0.152 LOC100128338
hypothetical LOC100128338
chr4_-_53220073 0.152 NM_022832
USP46
ubiquitin specific peptidase 46
chr1_-_204455269 0.152 NM_001007544
C1orf186
chromosome 1 open reading frame 186
chr2_-_42441798 0.149 NM_004718
COX7A2L
cytochrome c oxidase subunit VIIa polypeptide 2 like
chr19_+_16860807 0.149 NM_003950
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr19_+_53819460 0.149 SPHK2
sphingosine kinase 2
chr19_+_54352843 0.148 TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr19_-_14085979 0.137 NM_207518
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr1_-_149955415 0.136 NM_001172648
NM_001172649
CELF3

CUGBP, Elav-like family member 3

chr6_-_52549774 0.135 NM_012288
TRAM2
translocation associated membrane protein 2
chr7_+_75770801 0.132 HSPB1
heat shock 27kDa protein 1
chr19_+_7874701 0.132 MAP2K7
mitogen-activated protein kinase kinase 7
chr11_+_384199 0.131 NM_007183
PKP3
plakophilin 3
chr7_-_38341697 0.128 TRGV7
T cell receptor gamma variable 7 pseudogene
chr17_+_16259636 0.124 TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr9_-_135140450 0.120 NM_020469
ABO
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr11_+_125731305 0.119 NM_006278
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr2_+_112612429 0.118 NM_001128165
NM_153214
FBLN7

fibulin 7

chr19_+_54352809 0.116 NM_001195227
NM_017636
TRPM4

transient receptor potential cation channel, subfamily M, member 4

chr20_+_43996717 0.116 NM_022104
PCIF1
PDX1 C-terminal inhibiting factor 1
chr9_-_135140425 0.115 ABO
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr3_-_12680329 0.115 RAF1
v-raf-1 murine leukemia viral oncogene homolog 1
chr1_+_19796119 0.115


chr5_+_78443357 0.111 NM_001713
BHMT
betaine--homocysteine S-methyltransferase
chr6_+_7053863 0.111 RREB1
ras responsive element binding protein 1
chr2_+_220200530 0.111 NM_005070
NM_201574
SLC4A3

solute carrier family 4, anion exchanger, member 3

chr11_-_310775 0.110 NM_021034
IFITM3
interferon induced transmembrane protein 3 (1-8U)
chr11_+_66499323 0.110 NM_001136485
C11orf86
chromosome 11 open reading frame 86
chr6_+_31903374 0.108 NM_005346
HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr6_+_31891509 0.106 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr5_+_167889123 0.105


chr7_-_92057561 0.104 FAM133B
family with sequence similarity 133, member B
chr17_-_71747867 0.104 NM_052916
RNF157
ring finger protein 157
chr11_-_63808699 0.102 BAD
BCL2-associated agonist of cell death
chr9_-_129564517 0.102 NM_001142532
NM_001142531
SH2D3C

SH2 domain containing 3C

chr19_+_7874765 0.102 MAP2K7
mitogen-activated protein kinase kinase 7
chr9_-_137731139 0.101 NM_001012415
NM_001101677
SOHLH1

spermatogenesis and oogenesis specific basic helix-loop-helix 1

chr17_-_35331435 0.099 ORMDL3
ORM1-like 3 (S. cerevisiae)
chr2_+_112612511 0.099 FBLN7
fibulin 7
chr19_-_4491024 0.099 NM_052972
LRG1
leucine-rich alpha-2-glycoprotein 1
chr6_-_31890765 0.099 NM_005527
HSPA1L
heat shock 70kDa protein 1-like
chr19_+_7874774 0.099 MAP2K7
mitogen-activated protein kinase kinase 7
chr3_+_52786642 0.098 NM_002215
ITIH1
inter-alpha (globulin) inhibitor H1
chr7_+_98994199 0.097 ZNF655
zinc finger protein 655
chr19_-_13074669 0.097 LYL1
lymphoblastic leukemia derived sequence 1
chr6_-_43585958 0.097 C6orf154
chromosome 6 open reading frame 154
chr19_+_7874764 0.097 NM_145185
MAP2K7
mitogen-activated protein kinase kinase 7
chr6_+_33276580 0.094 NM_001077516
NM_006979
SLC39A7

solute carrier family 39 (zinc transporter), member 7

chr1_-_154665807 0.093 NM_006365
C1orf61
chromosome 1 open reading frame 61
chr16_-_28425632 0.093 NM_145659
IL27
interleukin 27
chr1_+_154095883 0.092 NM_152280
SYT11
synaptotagmin XI
chr17_+_42641712 0.091 NM_002476
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr20_+_33593243 0.090 ERGIC3
ERGIC and golgi 3
chr9_-_130006309 0.090 NM_001131015
NM_012127
CIZ1

CDKN1A interacting zinc finger protein 1

chr7_+_30917939 0.090 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr19_-_16111695 0.089


chr20_+_33593191 0.088 NM_015966
NM_198398
ERGIC3

ERGIC and golgi 3

chr7_-_92057597 0.087 NM_001040057
NM_152789
FAM133B

family with sequence similarity 133, member B

chr1_+_10381671 0.085 NM_002631
PGD
phosphogluconate dehydrogenase
chr2_-_128332143 0.085 POLR2D
polymerase (RNA) II (DNA directed) polypeptide D
chr20_-_34807882 0.084 NM_022477
NM_032013
NDRG3

NDRG family member 3

chr14_-_105762742 0.083


chr19_+_7874762 0.083 MAP2K7
mitogen-activated protein kinase kinase 7
chr6_-_52549673 0.082 TRAM2
translocation associated membrane protein 2
chr19_-_44060729 0.082 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr12_+_56135353 0.082 NM_031479
INHBE
inhibin, beta E
chr5_+_133870175 0.081


chr17_-_37590910 0.081 NM_001524
HCRT
hypocretin (orexin) neuropeptide precursor
chr2_-_128332176 0.079 NM_004805
POLR2D
polymerase (RNA) II (DNA directed) polypeptide D
chr2_+_47021866 0.077 TTC7A
tetratricopeptide repeat domain 7A
chr11_-_310925 0.077 IFITM3
interferon induced transmembrane protein 3 (1-8U)
chr14_-_99911679 0.077 NM_004184
NM_213646
WARS

tryptophanyl-tRNA synthetase

chr16_+_31178828 0.076 ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr15_+_55786212 0.076 GRINL1A
glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A
chr19_+_56337368 0.075 NM_014385
NM_016543
SIGLEC7

sialic acid binding Ig-like lectin 7

chr9_+_139245029 0.075 NM_001177316
NM_001177317
SLC34A3

solute carrier family 34 (sodium phosphate), member 3

chr17_-_36981830 0.074 NM_000226
KRT9
keratin 9
chr8_-_30635207 0.074 NM_002095
GTF2E2
general transcription factor IIE, polypeptide 2, beta 34kDa
chr3_+_9933763 0.074 NM_032732
NM_153460
NM_153461
IL17RC


interleukin 17 receptor C


chr14_+_104117100 0.074 NM_001008404
C14orf180
chromosome 14 open reading frame 180
chr8_+_37672427 0.074 NM_025069
ZNF703
zinc finger protein 703
chr15_-_88148177 0.074 ANPEP
alanyl (membrane) aminopeptidase
chr15_+_55786145 0.073 NM_001018102
NM_015532
GRINL1A

glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A

chr19_+_540849 0.073 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr7_-_156161130 0.073


chr18_+_27925859 0.073 RNF138
ring finger protein 138
chr19_-_4491078 0.072 LRG1
leucine-rich alpha-2-glycoprotein 1
chr15_+_30797466 0.071 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chrX_-_48866963 0.071 NM_015698
GPKOW
G patch domain and KOW motifs
chr1_-_6448737 0.071 NM_001039664
NM_003790
NM_148965
NM_148966
NM_148967
NM_148970
TNFRSF25





tumor necrosis factor receptor superfamily, member 25





chr3_-_197498980 0.071 NM_005017
PCYT1A
phosphate cytidylyltransferase 1, choline, alpha
chr18_+_27925815 0.069 NM_016271
RNF138
ring finger protein 138
chr2_-_200030944 0.068 NM_001172509
SATB2
SATB homeobox 2
chr17_+_55139644 0.068 NM_030938
VMP1
vacuole membrane protein 1
chr20_+_33593247 0.068 ERGIC3
ERGIC and golgi 3
chr19_+_40321567 0.067 NM_021902
FXYD1
FXYD domain containing ion transport regulator 1
chr16_-_4105703 0.066 ADCY9
adenylate cyclase 9
chr1_-_94359266 0.066 NM_000350
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr1_+_165225121 0.065 NM_032858
MAEL
maelstrom homolog (Drosophila)
chr3_-_127258299 0.065 NM_001008487
SLC41A3
solute carrier family 41, member 3
chr16_+_88696172 0.063 FAM157C
family with sequence similarity 157, member C
chr1_+_11749385 0.063 C1orf167
chromosome 1 open reading frame 167
chr3_+_38512753 0.063 NM_001145464
NM_005107
EXOG

endo/exonuclease (5'-3'), endonuclease G-like

chr19_+_7874820 0.063 MAP2K7
mitogen-activated protein kinase kinase 7
chr3_-_15618067 0.062 NM_012260
HACL1
2-hydroxyacyl-CoA lyase 1
chr7_+_142270634 0.062 EPHB6
EPH receptor B6
chr12_-_55791202 0.062 STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr20_-_49818306 0.061 NM_006045
ATP9A
ATPase, class II, type 9A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.41 2.06e-02 GO:0055085 transmembrane transport

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.29 6.03e-03 GO:0016020 membrane
2.01 1.01e-02 GO:0005887 integral to plasma membrane
1.97 1.47e-02 GO:0031226 intrinsic to plasma membrane
1.66 2.70e-02 GO:0044459 plasma membrane part
1.36 2.70e-02 GO:0016021 integral to membrane
1.35 3.63e-02 GO:0031224 intrinsic to membrane

Nothing significant found in function category.