Motif ID: RORA.p2

Z-value: 0.621


Transcription factors associated with RORA.p2:

Gene SymbolEntrez IDGene Name
RORA 6095 RAR-related orphan receptor A

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RORAchr15_-_59308708-0.361.8e-01Click!


Activity profile for motif RORA.p2.

activity profile for motif RORA.p2


Sorted Z-values histogram for motif RORA.p2

Sorted Z-values for motif RORA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RORA.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_136889436 0.915 NM_001198614
NM_001198618
NM_001198619
MAP7


microtubule-associated protein 7


chr11_-_119514011 0.836 TRIM29
tripartite motif containing 29
chr17_+_38250122 0.787 NM_001158
NM_009590
AOC2

amine oxidase, copper containing 2 (retina-specific)

chr15_+_38296920 0.751 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr11_-_102156531 0.661 NM_002425
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr2_+_219180862 0.630 PLCD4
phospholipase C, delta 4
chr15_-_41000100 0.590 NM_173500
TTBK2
tau tubulin kinase 2
chr7_+_120756325 0.584 NM_057168
WNT16
wingless-type MMTV integration site family, member 16
chr2_+_219180875 0.563 NM_032726
PLCD4
phospholipase C, delta 4
chr1_-_84928473 0.549 NM_001166295
NM_001166417
NM_001166293
NM_001166294
NM_014021
SSX2IP




synovial sarcoma, X breakpoint 2 interacting protein




chr2_+_219180821 0.543 PLCD4
phospholipase C, delta 4
chrX_-_62564934 0.467 LOC92249
hypothetical LOC92249
chr17_+_23394062 0.450 NLK
nemo-like kinase
chr19_+_1220244 0.436 NM_001280
CIRBP
cold inducible RNA binding protein
chr11_+_109468734 0.391 ZC3H12C
zinc finger CCCH-type containing 12C
chr3_-_24511456 0.384 THRB
thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
chr14_-_74669864 0.349 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr7_-_106991941 0.344 NM_001161520
NM_006348
NM_181733
COG5


component of oligomeric golgi complex 5


chr19_-_7604569 0.337 NM_174895
PCP2
Purkinje cell protein 2
chr11_+_4522993 0.298 NM_001004137
OR52M1
olfactory receptor, family 52, subfamily M, member 1
chr11_+_13255836 0.291 NM_001030272
NM_001030273
NM_001178
ARNTL


aryl hydrocarbon receptor nuclear translocator-like


chr13_-_26232777 0.278 NM_005288
GPR12
G protein-coupled receptor 12
chr1_-_35692668 0.277 KIAA0319L
KIAA0319-like
chr5_+_134209628 0.254 C5orf24
chromosome 5 open reading frame 24
chr1_+_67404756 0.250 NM_144701
IL23R
interleukin 23 receptor
chr8_-_134141586 0.244 NM_006748
SLA
Src-like-adaptor
chr11_+_13255913 0.241 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr12_+_49522967 0.238 NM_182559
TMPRSS12
transmembrane (C-terminal) protease, serine 12
chr1_-_148936123 0.233 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr15_-_43209348 0.233 NM_144565
DUOXA1
dual oxidase maturation factor 1
chr10_-_52315390 0.231 A1CF
APOBEC1 complementation factor
chr12_+_54700955 0.227 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr3_-_126215069 0.226 HEG1
HEG homolog 1 (zebrafish)
chr10_-_52315436 0.224 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr17_-_36113502 0.221 NM_019016
KRT24
keratin 24
chr17_-_32730804 0.221 NM_198837
NM_198838
ACACA

acetyl-CoA carboxylase alpha

chr2_+_121271336 0.218 NM_005270
GLI2
GLI family zinc finger 2
chr11_+_13255905 0.216 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_13255925 0.215 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr6_+_37360144 0.212 TBC1D22B
TBC1 domain family, member 22B
chr10_-_100164877 0.202 NM_032709
PYROXD2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr4_+_144325502 0.201 NM_032557
USP38
ubiquitin specific peptidase 38
chr19_+_43847049 0.199


chr16_-_15095590 0.188 NM_018427
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr1_+_227506751 0.185 NM_006542
SPHAR
S-phase response (cyclin related)
chr5_-_154210341 0.184 C5orf4
chromosome 5 open reading frame 4
chr11_+_13255952 0.183 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr5_+_134209268 0.182 NM_152409
C5orf24
chromosome 5 open reading frame 24
chr11_+_13255948 0.180 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr19_-_55156118 0.179 NM_001135163
NM_052884
SIGLEC11

sialic acid binding Ig-like lectin 11

chr14_-_89868006 0.179 NM_017970
NM_199043
C14orf102

chromosome 14 open reading frame 102

chr6_-_112033752 0.178 TRAF3IP2
TRAF3 interacting protein 2
chr1_+_17719405 0.168 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr16_-_1772577 0.167 NM_080861
SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr10_-_64698831 0.167 NM_004241
JMJD1C
jumonji domain containing 1C
chr1_-_150328153 0.166 NM_001008536
TCHHL1
trichohyalin-like 1
chr1_-_233879617 0.165 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr19_+_62483606 0.157 NM_006635
ZNF460
zinc finger protein 460
chr10_-_103568162 0.156 MGEA5
meningioma expressed antigen 5 (hyaluronidase)
chr10_+_102285690 0.156 HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr1_-_41259973 0.152 NM_001168247
NM_144990
SLFNL1

schlafen-like 1

chr17_-_46140015 0.152 NM_052855
ANKRD40
ankyrin repeat domain 40
chr10_-_105835609 0.150 NM_000494
COL17A1
collagen, type XVII, alpha 1
chr10_-_103568171 0.148 MGEA5
meningioma expressed antigen 5 (hyaluronidase)
chr5_+_134209444 0.143 NM_001135586
C5orf24
chromosome 5 open reading frame 24
chr17_-_15495534 0.141 TRIM16
tripartite motif containing 16
chr10_-_103568169 0.141 MGEA5
meningioma expressed antigen 5 (hyaluronidase)
chr12_+_92487728 0.139 NM_003877
SOCS2
suppressor of cytokine signaling 2
chr1_-_33585848 0.136


chr16_-_1772572 0.135 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr6_+_37429800 0.131 RNF8
ring finger protein 8
chr9_-_41944687 0.130 MGC21881
hypothetical locus MGC21881
chrX_-_114703273 0.130


chr3_+_51837608 0.127 NM_001085479
IQCF3
IQ motif containing F3
chr7_+_18501876 0.124 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr11_-_128567302 0.117 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr1_+_46151845 0.116 MAST2
microtubule associated serine/threonine kinase 2
chr12_-_54497770 0.114 SARNP
SAP domain containing ribonucleoprotein
chr3_+_1109619 0.112 NM_014461
CNTN6
contactin 6
chr17_+_23393744 0.111 NM_016231
NLK
nemo-like kinase
chr10_-_103568197 0.111 NM_001142434
NM_012215
MGEA5

meningioma expressed antigen 5 (hyaluronidase)

chr16_+_1772929 0.105 NM_012225
NUBP2
nucleotide binding protein 2 (MinD homolog, E. coli)
chr11_+_131285747 0.104 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr11_-_4585947 0.102 NM_018073
TRIM68
tripartite motif containing 68
chr3_+_48463117 0.102 ATRIP
ATR interacting protein
chr4_+_110968594 0.101 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr7_+_117651947 0.100 NM_019644
ANKRD7
ankyrin repeat domain 7
chr6_+_37429776 0.097 RNF8
ring finger protein 8
chr12_+_53534565 0.096 NM_058173
MUCL1
mucin-like 1
chr5_-_134942867 0.095 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chr6_+_121798443 0.095 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr11_+_13255967 0.095 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr9_-_115877104 0.094 AMBP
alpha-1-microglobulin/bikunin precursor
chr1_+_28637247 0.093 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr4_-_120462705 0.092 NM_000134
FABP2
fatty acid binding protein 2, intestinal
chr5_-_154210350 0.092 C5orf4
chromosome 5 open reading frame 4
chr4_+_144325533 0.092 USP38
ubiquitin specific peptidase 38
chr16_+_1773004 0.091 NUBP2
nucleotide binding protein 2 (MinD homolog, E. coli)
chr11_+_55869996 0.090 NM_001002907
OR8K1
olfactory receptor, family 8, subfamily K, member 1
chr8_-_72436832 0.090 EYA1
eyes absent homolog 1 (Drosophila)
chr2_+_170742900 0.089 NM_001083615
NM_001171642
NM_138995
MYO3B


myosin IIIB


chr16_+_16233979 0.083 NOMO2
NODAL modulator 2
chr19_-_10352172 0.082 TYK2
tyrosine kinase 2
chr15_-_63871492 0.080 DENND4A
DENN/MADD domain containing 4A
chr1_+_196148241 0.080 NM_001014434
LHX9
LIM homeobox 9
chrX_-_148580602 0.079 NM_005366
MAGEA11
melanoma antigen family A, 11
chr10_+_102285562 0.078 NM_017902
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr1_+_150749943 0.076 NM_178438
LCE5A
late cornified envelope 5A
chr11_-_67028415 0.073 PITPNM1
phosphatidylinositol transfer protein, membrane-associated 1
chr3_+_48463184 0.072 NM_032166
NM_130384
TREX1
ATRIP

three prime repair exonuclease 1
ATR interacting protein

chr18_+_30327243 0.072 NM_001198945
NM_001392
NM_032975
NM_032979
DTNA



dystrobrevin, alpha



chr2_-_30883775 0.071 NM_144575
CAPN13
calpain 13
chr7_-_83662152 0.071 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr16_+_16233989 0.069 NOMO2
NODAL modulator 2
chr18_+_30327341 0.068 DTNA
dystrobrevin, alpha
chr10_+_91127792 0.066 NM_001010987
IFIT1B
interferon-induced protein with tetratricopeptide repeats 1B
chr8_-_142307854 0.064 NM_001080431
SLC45A4
solute carrier family 45, member 4
chr6_+_26212082 0.063 NM_003542
HIST1H4C
histone cluster 1, H4c
chr12_-_54497751 0.063 SARNP
SAP domain containing ribonucleoprotein
chr6_-_34209250 0.061 NM_000841
GRM4
glutamate receptor, metabotropic 4
chr2_+_138975946 0.060


chr6_+_43845915 0.055 NM_001025366
NM_001025367
NM_001025368
NM_001025369
NM_001025370
NM_001033756
NM_001171622
NM_001171623
NM_001171624
NM_001171625
NM_001171626
NM_001171627
NM_001171628
NM_001171629
NM_001171630
NM_003376
VEGFA















vascular endothelial growth factor A















chr5_+_66160359 0.055 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr12_-_55637648 0.053 NM_003708
RDH16
retinol dehydrogenase 16 (all-trans)
chr2_+_119416214 0.051 NM_006770
MARCO
macrophage receptor with collagenous structure
chr16_+_16233996 0.050 NOMO1
NODAL modulator 1
chr8_-_120720200 0.050 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr9_-_138462384 0.050 SEC16A
SEC16 homolog A (S. cerevisiae)
chr1_+_78243181 0.049 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr17_-_36981830 0.049 NM_000226
KRT9
keratin 9
chr6_-_155677303 0.048 NM_016020
TFB1M
transcription factor B1, mitochondrial
chr7_+_128795178 0.047 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr1_+_170017430 0.046 METTL13
methyltransferase like 13
chrX_+_56772391 0.044 LOC550643
hypothetical LOC550643
chr12_-_46405477 0.043 NM_001172439
NM_001172440
NM_006025
ENDOU


endonuclease, polyU-specific


chr16_+_16233955 0.043 NOMO2
NODAL modulator 2
chr17_-_2250967 0.042 NM_020310
MNT
MAX binding protein
chr6_-_155677254 0.042 TFB1M
transcription factor B1, mitochondrial
chr15_-_74963246 0.042 NM_020843
SCAPER
S-phase cyclin A-associated protein in the ER
chr4_+_140442070 0.042 NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr3_+_44571600 0.042 NM_018651
NM_025169
ZNF167

zinc finger protein 167

chrX_-_151672985 0.041 NM_005361
NM_175742
NM_175743
MAGEA2


melanoma antigen family A, 2


chr1_+_44217435 0.041 NM_003780
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr6_+_43845875 0.041 VEGFA
vascular endothelial growth factor A
chr1_-_246503738 0.040 NM_001004695
OR2T33
olfactory receptor, family 2, subfamily T, member 33
chr6_-_152664906 0.039 SYNE1
spectrin repeat containing, nuclear envelope 1
chr1_-_103269356 0.039 COL11A1
collagen, type XI, alpha 1
chr19_-_3930828 0.039 EEF2
eukaryotic translation elongation factor 2
chr1_-_155053124 0.037 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr16_-_21739231 0.036 RRN3P1
RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
chr20_-_1257782 0.036 SDCBP2
syndecan binding protein (syntenin) 2
chr3_-_117647053 0.035 NM_002338
LSAMP
limbic system-associated membrane protein
chr17_+_29670171 0.035 NM_005623
CCL8
chemokine (C-C motif) ligand 8
chr1_-_201162938 0.033 KLHL12
kelch-like 12 (Drosophila)
chrX_-_33139349 0.033 NM_004006
DMD
dystrophin
chr16_+_16233972 0.033 NOMO2
NODAL modulator 2
chr7_+_128795280 0.033 AHCYL2
adenosylhomocysteinase-like 2
chr6_-_112033775 0.032 TRAF3IP2
TRAF3 interacting protein 2
chr9_+_66293049 0.032 MGC21881
hypothetical locus MGC21881
chr11_+_55776251 0.031 NM_001004747
OR5T3
olfactory receptor, family 5, subfamily T, member 3
chr16_+_16234008 0.031 NOMO1
NODAL modulator 1
chr1_-_176205970 0.029 SEC16B
SEC16 homolog B (S. cerevisiae)
chr1_+_109057078 0.029 NM_001144937
FNDC7
fibronectin type III domain containing 7
chr3_-_24511180 0.029 NM_001128176
NM_000461
NM_001128177
THRB


thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)


chr12_+_63958689 0.029 NM_001031679
NM_001193460
NM_198080
MSRB3


methionine sulfoxide reductase B3


chr15_+_100319349 0.026 LOC100134445
WASH1
WASH3P
hypothetical LOC100134445
WAS protein family homolog 1
WAS protein family homolog 3 pseudogene
chrX_+_64804235 0.026 NM_002444
MSN
moesin
chr1_+_176577228 0.026 NM_004841
RASAL2
RAS protein activator like 2
chr12_+_103677388 0.026 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr12_+_54672766 0.025 RAB5B
RAB5B, member RAS oncogene family
chr4_+_25931282 0.025 RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr1_-_23376860 0.024 LUZP1
leucine zipper protein 1
chr2_+_102294393 0.024 NM_016232
IL18R1
IL1RL1
interleukin 18 receptor 1
interleukin 1 receptor-like 1
chr14_-_100420936 0.023 NM_001134888
RTL1
retrotransposon-like 1
chr19_+_8384181 0.023 NM_001005415
NM_001005416
NM_016496
MARCH2


membrane-associated ring finger (C3HC4) 2


chr1_+_103999663 0.023 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr1_-_40930295 0.022 LOC100130557
hypothetical LOC100130557
chr1_+_40635058 0.021 NM_001198980
SMAP2
small ArfGAP2
chr2_+_232951487 0.019 NM_001632
ALPP
alkaline phosphatase, placental
chr2_-_165186232 0.019 GRB14
growth factor receptor-bound protein 14
chr11_-_65412409 0.018 NM_004214
NM_198897
FIBP

fibroblast growth factor (acidic) intracellular binding protein

chr3_-_17716515 0.018 NM_001134381
TBC1D5
TBC1 domain family, member 5
chr17_+_7474128 0.018 SHBG
sex hormone-binding globulin
chr15_-_38118608 0.018 NM_003134
SRP14
signal recognition particle 14kDa (homologous Alu RNA binding protein)
chr4_-_151990061 0.018 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr7_-_128203079 0.017 NM_001708
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr1_-_246880807 0.017 NM_001001824
OR2T27
olfactory receptor, family 2, subfamily T, member 27
chr7_-_42938255 0.017 PSMA2
proteasome (prosome, macropain) subunit, alpha type, 2
chr3_+_142587973 0.016


chr10_+_18081223 0.016 NM_001098844
FAM23A
family with sequence similarity 23, member A
chr12_+_2792047 0.016 NM_018463
ITFG2
integrin alpha FG-GAP repeat containing 2
chr10_+_51219558 0.015 NM_002443
NM_138634
MSMB

microseminoprotein, beta-

chr8_+_36760999 0.015 NM_001031836
KCNU1
potassium channel, subfamily U, member 1
chr2_+_27154938 0.015 NM_007046
EMILIN1
elastin microfibril interfacer 1
chr11_-_72057755 0.015 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr16_-_88623809 0.013 NM_001214
C16orf3
chromosome 16 open reading frame 3
chr22_-_31732648 0.013 NM_003490
NM_133633
SYN3

synapsin III

chr14_+_93562500 0.013 OTUB2
OTU domain, ubiquitin aldehyde binding 2
chrX_+_65152004 0.013


chr14_-_90780604 0.012 NM_001177676
GPR68
G protein-coupled receptor 68

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
72.15 3.19e-03 GO:0034314 Arp2/3 complex-mediated actin nucleation
48.10 1.57e-02 GO:0045010 actin nucleation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
26.24 2.56e-02 GO:0071203 WASH complex

Nothing significant found in function category.