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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: RREB1.p2

Z-value: 1.510

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr20_-_22512893	2.458		FOXA2	forkhead box A2
chr3_+_187917791	2.011	NM_000893 NM_001102416 NM_001166451	KNG1	kininogen 1
chr2_+_233443237	1.955	NM_206895	C2orf82	chromosome 2 open reading frame 82
chr20_-_22513050	1.822	NM_021784	FOXA2	forkhead box A2
chr14_-_36059084	1.557	NM_001079668	NKX2-1	NK2 homeobox 1
chr22_-_30929463	1.544	NM_001098527	RFPL2	ret finger protein-like 2
chrX_+_17665483	1.266	NM_001037535 NM_001037536 NM_001037540 NM_006746	SCML1	sex comb on midleg-like 1 (Drosophila)
chr8_-_139995417	1.214	NM_152888	COL22A1	collagen, type XXII, alpha 1
chr20_+_44070946	1.138	NM_004994	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr20_-_51644187	1.125		ZNF217	zinc finger protein 217
chr11_+_10428799	1.059	NM_000480	AMPD3	adenosine monophosphate deaminase 3
chr2_+_72998111	0.877	NM_004097	EMX1	empty spiracles homeobox 1
chr16_-_3225070	0.867	NM_001145447 NM_003454	ZNF200	zinc finger protein 200
chr20_-_49592444	0.864		NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr16_-_10183616	0.853	NM_001134407	GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr3_+_50629593	0.844		MAPKAPK3	mitogen-activated protein kinase-activated protein kinase 3
chr6_-_29703725	0.834		GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr6_-_32659958	0.802		HLA-DRB1 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 5
chr1_+_3378030	0.801		ARHGEF16	Rho guanine nucleotide exchange factor (GEF) 16
chr3_-_10522267	0.780	NM_001001331 NM_001683	ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
chr3_-_10522221	0.778		ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
chr2_+_42649348	0.760		MTA3	metastasis associated 1 family, member 3
chr2_+_42649105	0.753	NM_020744	MTA3	metastasis associated 1 family, member 3
chr6_+_44203335	0.740	NM_018426	TMEM63B	transmembrane protein 63B
chr1_-_226671205	0.719	NM_001024940 NM_001134855 NM_016102	TRIM17	tripartite motif containing 17
chr1_-_30977931	0.708		LAPTM5	lysosomal protein transmembrane 5
chr6_+_32229771	0.693		PPT2-EGFL8 PPT2	PPT2-EGFL8 read-through transcript palmitoyl-protein thioesterase 2
chr10_+_115428924	0.692	NM_033340	CASP7	caspase 7, apoptosis-related cysteine peptidase
chr14_-_20636337	0.687		ZNF219	zinc finger protein 219
chr1_-_40903897	0.673	NM_014747	RIMS3	regulating synaptic membrane exocytosis 3
chr21_+_42946719	0.657	NM_001001567 NM_001001568 NM_001001569 NM_001001570 NM_001001571 NM_001001572 NM_001001573 NM_001001574 NM_001001575 NM_001001576 NM_001001577 NM_001001578 NM_001001579 NM_001001580 NM_001001581 NM_001001582 NM_001001583 NM_001001584 NM_001001585 NM_002606	PDE9A	phosphodiesterase 9A
chr1_-_149955870	0.648	NM_007185	CELF3	CUGBP, Elav-like family member 3
chr11_-_74740298	0.641	NM_004041 NM_020251	ARRB1	arrestin, beta 1
chr1_-_226670928	0.639		TRIM17	tripartite motif containing 17
chr6_-_29703913	0.635	NM_021903	GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr8_+_144706699	0.633	NM_001166237	GSDMD	gasdermin D
chr21_+_41663853	0.624		MX2	myxovirus (influenza virus) resistance 2 (mouse)
chr17_+_72789086	0.623	NM_001113491	SEPT9	septin 9
chr22_-_37124799	0.616		LOC400927	TPTE and PTEN homologous inositol lipid phosphatase pseudogene
chr22_+_22529058	0.615	NM_001024938 NM_030807	SLC2A11	solute carrier family 2 (facilitated glucose transporter), member 11
chr2_-_227372574	0.615		IRS1	insulin receptor substrate 1
chr3_-_10522340	0.604		ATP2B2	ATPase, Ca++ transporting, plasma membrane 2
chr2_-_148494732	0.596	NM_001190882 NM_001190879 NM_002552 NM_001190881 NM_181741	ORC4	origin recognition complex, subunit 4
chr16_+_80036275	0.590	NM_198390	CMIP	c-Maf-inducing protein
chr17_-_40858775	0.588	NM_199282	ARHGAP27	Rho GTPase activating protein 27
chr21_+_44699796	0.581	NM_030891	LRRC3	leucine rich repeat containing 3
chr16_+_87450991	0.574	NM_016209	TRAPPC2L	trafficking protein particle complex 2-like
chr2_+_190916571	0.566		INPP1	inositol polyphosphate-1-phosphatase
chr2_+_242679507	0.562		LOC728323	hypothetical LOC728323
chr20_+_55359706	0.559		RAE1	RAE1 RNA export 1 homolog (S. pombe)
chr20_+_55359551	0.557	NM_003610	RAE1	RAE1 RNA export 1 homolog (S. pombe)
chr16_+_70217564	0.552	NM_001017967 NM_052858	MARVELD3	MARVEL domain containing 3
chr20_-_62151216	0.544	NM_018419	SOX18	SRY (sex determining region Y)-box 18
chr1_-_40903700	0.543		RIMS3	regulating synaptic membrane exocytosis 3
chr17_-_7323528	0.540		ZBTB4	zinc finger and BTB domain containing 4
chr2_+_190916440	0.540	NM_001128928 NM_002194	INPP1	inositol polyphosphate-1-phosphatase
chr20_+_35407872	0.533	NM_198291	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr6_+_32230172	0.529		PPT2	palmitoyl-protein thioesterase 2
chr1_-_149955415	0.528	NM_001172648 NM_001172649	CELF3	CUGBP, Elav-like family member 3
chr17_-_71352182	0.515	NM_199242	UNC13D	unc-13 homolog D (C. elegans)
chr19_+_37902518	0.515	NM_001110822	TDRD12	tudor domain containing 12
chr9_+_70509925	0.514	NM_003558	PIP5K1B	phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr20_+_48032918	0.511	NM_005985	SNAI1	snail homolog 1 (Drosophila)
chr9_-_115901157	0.503	NM_138424	KIF12	kinesin family member 12
chr11_+_63809877	0.497		GPR137	G protein-coupled receptor 137
chr11_+_63810157	0.497	NM_001170880 NM_020155	GPR137	G protein-coupled receptor 137
chr10_-_43082372	0.494	NM_145313	RASGEF1A	RasGEF domain family, member 1A
chr2_+_191222077	0.493	NM_005966	NAB1	NGFI-A binding protein 1 (EGR1 binding protein 1)
chr2_+_8739563	0.492	NM_002166	ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chrX_-_48578878	0.490	NM_013271	PCSK1N	proprotein convertase subtilisin/kexin type 1 inhibitor
chr14_-_34001164	0.489	NM_138288	C14orf147	chromosome 14 open reading frame 147
chr12_+_69046241	0.488	NM_014505	KCNMB4	potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr17_+_44340852	0.482		UBE2Z	ubiquitin-conjugating enzyme E2Z
chr7_+_134567270	0.482	NM_182489	STRA8	stimulated by retinoic acid gene 8 homolog (mouse)
chr16_-_49742651	0.482	NM_002968	SALL1	sal-like 1 (Drosophila)
chr20_-_49592654	0.473	NM_012340 NM_173091	NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr10_-_98470164	0.467	NM_152309	PIK3AP1	phosphoinositide-3-kinase adaptor protein 1
chr11_-_404975	0.464	NM_001135054	SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr2_-_20288647	0.463	NM_001006946	SDC1	syndecan 1
chr2_-_128149112	0.462	NM_001136037 NM_001161403	LIMS2	LIM and senescent cell antigen-like domains 2
chr2_-_20288108	0.458	NM_002997	SDC1	syndecan 1
chr12_+_970613	0.448	NM_178039 NM_178040	ERC1	ELKS/RAB6-interacting/CAST family member 1
chr14_-_64638809	0.448		MAX	MYC associated factor X
chr19_-_18913032	0.446	NM_004838	HOMER3	homer homolog 3 (Drosophila)
chr1_-_202647526	0.445	NM_032833	PPP1R15B	protein phosphatase 1, regulatory (inhibitor) subunit 15B
chr8_-_125252884	0.440		C8orf78	chromosome 8 open reading frame 78
chr1_-_23623713	0.439	NM_003196	TCEA3	transcription elongation factor A (SII), 3
chr14_+_23508922	0.436	NM_001193636 NM_001193637 NM_001193635	DHRS4L2 DHRS4L1	dehydrogenase/reductase (SDR family) member 4 like 2 dehydrogenase/reductase (SDR family) member 4 like 1
chr17_+_16259636	0.433		TRPV2	transient receptor potential cation channel, subfamily V, member 2
chr17_-_1335763	0.432	NM_001080950	MYO1C	myosin IC
chr6_-_139654807	0.431	NM_153235	TXLNB	taxilin beta
chr11_+_10428443	0.431	NM_001172431	AMPD3	adenosine monophosphate deaminase 3
chr20_+_42309371	0.429		GDAP1L1	ganglioside-induced differentiation-associated protein 1-like 1
chr16_-_70400040	0.426		AP1G1	adaptor-related protein complex 1, gamma 1 subunit
chr17_+_16259573	0.425	NM_016113	TRPV2	transient receptor potential cation channel, subfamily V, member 2
chr17_-_33982580	0.425		SRCIN1	SRC kinase signaling inhibitor 1
chr3_-_185578621	0.415	NM_000460 NM_001177597 NM_001177598	THPO	thrombopoietin
chr17_-_64108843	0.414		FAM20A	family with sequence similarity 20, member A
chr16_+_2504001	0.414		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr2_-_224612177	0.412	NM_001136528 NM_006216	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr8_-_111056099	0.411	NM_014379	KCNV1	potassium channel, subfamily V, member 1
chr16_+_29378694	0.411	NM_001017390 NM_177552	SULT1A4 SULT1A3	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr5_+_6501735	0.410	NM_001145161	UBE2QL1	ubiquitin-conjugating enzyme E2Q family-like 1
chr11_+_34029764	0.406	NM_005898 NM_203364	CAPRIN1	cell cycle associated protein 1
chr1_+_945399	0.405
chr20_+_43531806	0.400	NM_006103	WFDC2	WAP four-disulfide core domain 2
chr20_+_8060762	0.399	NM_015192 NM_182734	PLCB1	phospholipase C, beta 1 (phosphoinositide-specific)
chr6_+_33486750	0.399	NM_002636 NM_024165	PHF1	PHD finger protein 1
chr16_+_29724926	0.397		MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr11_-_110755366	0.397	NM_006235	POU2AF1	POU class 2 associating factor 1
chr14_+_28305922	0.395	NM_005249	FOXG1	forkhead box G1
chr19_+_14405216	0.395		PKN1	protein kinase N1
chr2_+_20729904	0.394	NM_182828	GDF7	growth differentiation factor 7
chr2_+_219453487	0.394	NM_025216	WNT10A	wingless-type MMTV integration site family, member 10A
chr12_+_54832470	0.389	NM_002475	MYL6B	myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr17_+_16259812	0.387		TRPV2	transient receptor potential cation channel, subfamily V, member 2
chr14_+_31616196	0.386	NM_001030055 NM_001173	ARHGAP5	Rho GTPase activating protein 5
chr8_+_120497732	0.385	NM_002514	NOV	nephroblastoma overexpressed gene
chr16_+_28742066	0.384		ATXN2L	ataxin 2-like
chr10_-_42507180	0.382
chr21_+_44871467	0.380	NM_198690	KRTAP10-9	keratin associated protein 10-9
chr17_-_43470134	0.378	NM_016429	COPZ2	coatomer protein complex, subunit zeta 2
chr19_+_16039170	0.375	NM_001145160	TPM4	tropomyosin 4
chr20_+_56900116	0.374	NM_001077488	GNAS	GNAS complex locus
chr18_-_70110089	0.372	NM_001190807 NM_001914 NM_148923	CYB5A	cytochrome b5 type A (microsomal)
chr20_-_9767406	0.371	NM_020341 NM_177990	PAK7	p21 protein (Cdc42/Rac)-activated kinase 7
chr19_-_13977875	0.370		RFX1	regulatory factor X, 1 (influences HLA class II expression)
chr2_+_218972963	0.369	NM_182642	CTDSP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr7_+_29200636	0.368	NM_004067	CHN2	chimerin (chimaerin) 2
chr21_+_46473494	0.367		MCM3AP-AS1	MCM3AP antisense RNA 1 (non-protein coding)
chr13_-_40138607	0.367	NM_002015	FOXO1	forkhead box O1
chr6_+_32229599	0.367	NM_005155	PPT2-EGFL8 PPT2	PPT2-EGFL8 read-through transcript palmitoyl-protein thioesterase 2
chr1_-_240754620	0.367	NM_152666	PLD5	phospholipase D family, member 5
chr2_+_154436670	0.365	NM_052917	GALNT13	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
chr2_+_218833982	0.365	NM_001077191 NM_001077194 NM_170699	GPBAR1	G protein-coupled bile acid receptor 1
chr22_-_30930717	0.364	NM_001159545	RFPL2	ret finger protein-like 2
chr19_-_51168396	0.363	NM_002516	NOVA2	neuro-oncological ventral antigen 2
chr10_+_22650145	0.363		BMI1	BMI1 polycomb ring finger oncogene
chr6_+_2945025	0.360	NM_000904	NQO2	NAD(P)H dehydrogenase, quinone 2
chr16_-_28528780	0.360	NM_001055 NM_177529	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr12_+_56135353	0.359	NM_031479	INHBE	inhibin, beta E
chr1_+_78126787	0.359	NM_001172309 NM_144573	NEXN	nexilin (F actin binding protein)
chr16_+_28741861	0.359		ATXN2L	ataxin 2-like
chr1_-_199259447	0.358	NM_017596	KIF21B	kinesin family member 21B
chr14_+_23610582	0.357	NM_006032	CPNE6	copine VI (neuronal)
chr19_+_45996881	0.357	NM_080732	EGLN2	egl nine homolog 2 (C. elegans)
chr1_-_177465358	0.357		ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2
chr16_+_56286212	0.356	NM_032269	CCDC135	coiled-coil domain containing 135
chr11_+_64705261	0.355	NM_001198868	CAPN1	calpain 1, (mu/I) large subunit
chr20_+_34206070	0.353	NM_012156	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr17_+_52688842	0.352	NM_138962	MSI2	musashi homolog 2 (Drosophila)
chr18_-_26935427	0.350		DSC2	desmocollin 2
chr17_-_71352090	0.347		UNC13D	unc-13 homolog D (C. elegans)
chr14_+_20608179	0.346	NM_018071	ARHGEF40	Rho guanine nucleotide exchange factor (GEF) 40
chr17_-_34603577	0.345		CACNB1	calcium channel, voltage-dependent, beta 1 subunit
chr10_-_21825879	0.344		C10orf114	chromosome 10 open reading frame 114
chr19_-_4017739	0.343	NM_015898	ZBTB7A	zinc finger and BTB domain containing 7A
chr2_+_181553613	0.338		UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr8_+_26204997	0.338		PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr15_+_38430517	0.336	NM_001145643	PHGR1	proline/histidine/glycine-rich 1
chr2_-_32089557	0.335		MEMO1	mediator of cell motility 1
chrX_+_154264931	0.335	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated (intronic transcript) 2 coagulation factor VIII-associated (intronic transcript) 3 coagulation factor VIII-associated (intronic transcript) 1
chr5_+_172193826	0.326	NM_001031711	ERGIC1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr16_+_28741908	0.325	NM_007245 NM_145714 NM_148414 NM_148415 NM_148416	ATXN2L	ataxin 2-like
chr17_+_5914364	0.323	NM_015253	WSCD1	WSC domain containing 1
chr12_+_119418294	0.322		DYNLL1	dynein, light chain, LC8-type 1
chrX_+_149612488	0.322	NM_003828	MTMR1	myotubularin related protein 1
chr2_+_11190629	0.320	NM_182500	C2orf50	chromosome 2 open reading frame 50
chr17_+_52266451	0.315	NM_003647	DGKE	diacylglycerol kinase, epsilon 64kDa
chr7_+_21434818	0.315
chr16_-_30929217	0.315	NM_052874	STX1B	syntaxin 1B
chr14_-_23981493	0.312	NM_020195	SDR39U1	short chain dehydrogenase/reductase family 39U, member 1
chr12_+_119418215	0.312	NM_001037495 NM_003746	DYNLL1	dynein, light chain, LC8-type 1
chr8_-_71478041	0.312		NCOA2	nuclear receptor coactivator 2
chr2_+_231437745	0.311	NM_001012514 NM_001012516 NM_030926	ITM2C	integral membrane protein 2C
chr2_-_72224696	0.311		CYP26B1	cytochrome P450, family 26, subfamily B, polypeptide 1
chr2_+_54537842	0.311		SPTBN1	spectrin, beta, non-erythrocytic 1
chr14_+_23968979	0.310	NM_015299	KHNYN	KH and NYN domain containing
chr19_-_6453224	0.309	NM_006087	TUBB4	tubulin, beta 4
chr16_-_70400393	0.308	NM_001030007 NM_001128	AP1G1	adaptor-related protein complex 1, gamma 1 subunit
chr2_-_32089107	0.307	NM_001137602 NM_015955	MEMO1	mediator of cell motility 1
chr9_+_138997265	0.307	NM_207510	LCNL1	lipocalin-like 1
chrX_+_152561086	0.306	NM_001395	DUSP9	dual specificity phosphatase 9
chr12_-_51585004	0.303	NM_002273	KRT8	keratin 8
chr11_-_17454995	0.302	NM_000352	ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr19_-_60350122	0.302		TNNT1	troponin T type 1 (skeletal, slow)
chr2_+_231437905	0.302		ITM2C	integral membrane protein 2C
chr1_-_6162669	0.302	NM_015557	CHD5	chromodomain helicase DNA binding protein 5
chr19_+_40451842	0.301		USF2	upstream transcription factor 2, c-fos interacting
chr6_-_167195987	0.299		RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr16_+_28741873	0.298		ATXN2L	ataxin 2-like
chr2_+_241213334	0.297	NM_005301	GPR35	G protein-coupled receptor 35
chr17_+_75507750	0.297
chr3_-_13896618	0.297	NM_004625	WNT7A	wingless-type MMTV integration site family, member 7A
chr2_+_219532590	0.296	NM_003936	CDK5R2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr1_+_154318954	0.295		LMNA	lamin A/C
chr14_+_92883289	0.294	NM_182971	COX8C	cytochrome c oxidase subunit 8C
chr17_-_34014390	0.294		SRCIN1	SRC kinase signaling inhibitor 1
chr19_+_59820413	0.294	NM_006669	LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr2_-_218843088	0.293		AAMP	angio-associated, migratory cell protein

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.14	3.35e-11	GO:0065007	biological regulation
1.14	4.69e-09	GO:0050789	regulation of biological process
1.14	2.62e-08	GO:0050794	regulation of cellular process
1.21	8.02e-08	GO:0019222	regulation of metabolic process
1.37	1.36e-07	GO:0007399	nervous system development
1.21	2.94e-07	GO:0031323	regulation of cellular metabolic process
1.21	6.72e-07	GO:0080090	regulation of primary metabolic process
1.53	1.75e-06	GO:0045595	regulation of cell differentiation
1.20	2.08e-06	GO:0032502	developmental process
1.43	2.55e-06	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.21	3.73e-06	GO:0060255	regulation of macromolecule metabolic process
1.20	1.27e-05	GO:0007275	multicellular organismal development
1.31	1.73e-05	GO:0023051	regulation of signaling
1.07	6.16e-05	GO:0009987	cellular process
1.20	9.96e-05	GO:0048856	anatomical structure development
1.30	1.19e-04	GO:0009653	anatomical structure morphogenesis
1.23	1.28e-04	GO:0048519	negative regulation of biological process
1.39	1.38e-04	GO:0050793	regulation of developmental process
1.24	1.43e-04	GO:0048523	negative regulation of cellular process
1.21	2.74e-04	GO:0048518	positive regulation of biological process
1.30	3.20e-04	GO:0009966	regulation of signal transduction
1.20	4.16e-04	GO:0048731	system development
1.37	5.03e-04	GO:0048468	cell development
1.23	9.65e-04	GO:0048869	cellular developmental process
1.32	1.12e-03	GO:0031325	positive regulation of cellular metabolic process
1.30	1.17e-03	GO:0009893	positive regulation of metabolic process
1.16	1.23e-03	GO:0023052	signaling
1.21	1.44e-03	GO:0048522	positive regulation of cellular process
1.32	1.68e-03	GO:0010604	positive regulation of macromolecule metabolic process
1.36	1.82e-03	GO:0022008	neurogenesis
1.19	1.90e-03	GO:0051171	regulation of nitrogen compound metabolic process
1.45	1.98e-03	GO:0009887	organ morphogenesis
1.23	2.25e-03	GO:0030154	cell differentiation
1.52	2.49e-03	GO:0007268	synaptic transmission
1.24	2.57e-03	GO:0048583	regulation of response to stimulus
1.27	2.86e-03	GO:0065009	regulation of molecular function
1.19	2.86e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.61	2.91e-03	GO:0060284	regulation of cell development
1.36	3.11e-03	GO:0048699	generation of neurons
1.32	3.16e-03	GO:0051246	regulation of protein metabolic process
1.48	3.24e-03	GO:0007417	central nervous system development
1.54	3.73e-03	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.48	5.01e-03	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.55	5.42e-03	GO:0007420	brain development
1.19	5.69e-03	GO:0010468	regulation of gene expression
1.47	6.92e-03	GO:0019226	transmission of nerve impulse
1.47	6.92e-03	GO:0035637	multicellular organismal signaling
1.18	8.19e-03	GO:0031326	regulation of cellular biosynthetic process
1.31	8.30e-03	GO:0010646	regulation of cell communication
1.64	8.60e-03	GO:0045596	negative regulation of cell differentiation
1.36	8.84e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.39	8.98e-03	GO:0030182	neuron differentiation
1.18	9.81e-03	GO:0009889	regulation of biosynthetic process
1.31	9.95e-03	GO:0032268	regulation of cellular protein metabolic process
1.39	1.10e-02	GO:0051254	positive regulation of RNA metabolic process
1.90	1.36e-02	GO:0042692	muscle cell differentiation
1.45	1.47e-02	GO:0000904	cell morphogenesis involved in differentiation
1.36	1.47e-02	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.19	2.10e-02	GO:0051252	regulation of RNA metabolic process
1.35	2.67e-02	GO:2000026	regulation of multicellular organismal development
1.38	2.70e-02	GO:0030030	cell projection organization
1.51	2.76e-02	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.38	2.89e-02	GO:0032989	cellular component morphogenesis
1.39	2.95e-02	GO:0000902	cell morphogenesis
1.38	3.44e-02	GO:0045893	positive regulation of transcription, DNA-dependent
1.38	3.56e-02	GO:0001932	regulation of protein phosphorylation
1.62	3.86e-02	GO:0050767	regulation of neurogenesis
1.43	3.92e-02	GO:0048858	cell projection morphogenesis
1.41	4.12e-02	GO:0045892	negative regulation of transcription, DNA-dependent
1.15	4.23e-02	GO:0007165	signal transduction
1.54	4.32e-02	GO:0032940	secretion by cell
1.33	4.60e-02	GO:0031399	regulation of protein modification process
1.26	4.61e-02	GO:0051641	cellular localization
1.40	4.83e-02	GO:0051253	negative regulation of RNA metabolic process
1.53	4.89e-02	GO:0051093	negative regulation of developmental process
1.36	4.94e-02	GO:0042325	regulation of phosphorylation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.14	5.11e-06	GO:0005634	nucleus
1.44	2.10e-04	GO:0030054	cell junction
1.06	2.15e-04	GO:0044424	intracellular part
1.06	2.52e-04	GO:0005622	intracellular
1.17	1.29e-03	GO:0043234	protein complex
1.81	2.54e-03	GO:0005912	adherens junction
1.62	4.74e-03	GO:0016323	basolateral plasma membrane
1.73	6.97e-03	GO:0070161	anchoring junction
1.19	8.32e-03	GO:0005829	cytosol
1.31	1.35e-02	GO:0005624	membrane fraction
1.06	1.66e-02	GO:0043226	organelle
1.06	1.91e-02	GO:0043229	intracellular organelle
1.28	4.93e-02	GO:0005626	insoluble fraction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.18	2.95e-17	GO:0005515	protein binding
1.07	2.57e-07	GO:0005488	binding
1.48	2.80e-06	GO:0043565	sequence-specific DNA binding
1.35	1.34e-04	GO:0030528	transcription regulator activity
1.33	4.47e-04	GO:0001071	nucleic acid binding transcription factor activity
1.33	4.47e-04	GO:0003700	sequence-specific DNA binding transcription factor activity
1.50	6.61e-04	GO:0019904	protein domain specific binding
1.77	9.81e-04	GO:0003682	chromatin binding
1.71	4.12e-03	GO:0010843	promoter binding
1.64	1.82e-02	GO:0000975	regulatory region DNA binding
1.64	1.82e-02	GO:0001067	regulatory region nucleic acid binding
1.64	1.82e-02	GO:0044212	transcription regulatory region DNA binding
1.75	2.17e-02	GO:0008022	protein C-terminus binding