Motif ID: SOX17.p2

Z-value: 1.618


Transcription factors associated with SOX17.p2:

Gene SymbolEntrez IDGene Name
SOX17 64321 SRY (sex determining region Y)-box 17

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX17chr8_+_55533047-0.224.1e-01Click!


Activity profile for motif SOX17.p2.

activity profile for motif SOX17.p2


Sorted Z-values histogram for motif SOX17.p2

Sorted Z-values for motif SOX17.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX17.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_9046460 2.196 PPP1R3B
protein phosphatase 1, regulatory (inhibitor) subunit 3B
chr20_+_18742369 2.149 NM_178483
C20orf79
chromosome 20 open reading frame 79
chr1_-_26105230 2.038 NM_203401
STMN1
stathmin 1
chr19_-_51856129 1.975 NM_145056
DACT3
dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr18_-_22382497 1.806 NM_001142730
KCTD1
potassium channel tetramerisation domain containing 1
chr10_-_15170779 1.785 NM_001039844
ACBD7
acyl-CoA binding domain containing 7
chr19_-_6230797 1.655


chr6_-_72187168 1.510 C6orf155
chromosome 6 open reading frame 155
chr1_+_50344550 1.506 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr19_-_6230927 1.479 NM_005934
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr11_+_36274300 1.376 NM_001160167
PRR5L
proline rich 5 like
chr6_-_80303822 1.356 NM_001122769
NM_181714
LCA5

Leber congenital amaurosis 5

chr11_-_123130435 1.161 NM_001005188
OR6X1
olfactory receptor, family 6, subfamily X, member 1
chr2_-_37752272 1.150 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr7_-_5535726 1.143 ACTB
actin, beta
chr1_-_26105477 1.120 NM_001145454
NM_005563
STMN1

stathmin 1

chr12_-_57600564 1.047 LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr9_+_129199204 1.016 NM_014580
SLC2A8
solute carrier family 2 (facilitated glucose transporter), member 8
chr15_+_81906983 1.014 NM_003027
SH3GL3
SH3-domain GRB2-like 3
chr22_+_22703107 1.010 NM_001144931
LOC391322
D-dopachrome tautomerase-like
chr7_-_120823591 1.008 NM_001040020
NM_014888
FAM3C

family with sequence similarity 3, member C

chr7_-_120823556 0.996 FAM3C
family with sequence similarity 3, member C
chr17_+_23670247 0.993 NM_014573
TMEM97
transmembrane protein 97
chr11_+_13646727 0.991 NM_032228
FAR1
fatty acyl CoA reductase 1
chr15_+_82945223 0.979 NM_001007072
NM_017894
NM_181877
ZSCAN2


zinc finger and SCAN domain containing 2


chr12_-_102413875 0.978 NM_198521
NM_001099336
C12orf42

chromosome 12 open reading frame 42

chr11_+_13646806 0.967 FAR1
fatty acyl CoA reductase 1
chr15_-_32398220 0.948 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr12_-_57600336 0.921 NM_153377
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr19_+_11510578 0.920 NM_001299
CNN1
calponin 1, basic, smooth muscle
chrX_+_82649924 0.918 NM_000307
POU3F4
POU class 3 homeobox 4
chr4_-_83569572 0.907 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr12_-_120389419 0.901 KDM2B
lysine (K)-specific demethylase 2B
chr3_-_187309442 0.890 NM_004454
ETV5
ets variant 5
chr5_-_95323180 0.881 ELL2
elongation factor, RNA polymerase II, 2
chr11_+_48303047 0.874 NM_001004702
OR4C3
olfactory receptor, family 4, subfamily C, member 3
chr11_-_74914514 0.857 GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr10_+_104667991 0.831 NM_017649
NM_199076
NM_199077
CNNM2


cyclin M2


chr5_+_170668892 0.829 NM_021025
TLX3
T-cell leukemia homeobox 3
chr1_-_8799966 0.824 NM_001042681
NM_012102
RERE

arginine-glutamic acid dipeptide (RE) repeats

chr22_-_29052863 0.822 NM_031937
TBC1D10A
TBC1 domain family, member 10A
chr5_+_140835727 0.820 NM_002588
NM_032402
NM_032403
PCDHGC3


protocadherin gamma subfamily C, 3


chr7_+_882766 0.809 GET4
golgi to ER traffic protein 4 homolog (S. cerevisiae)
chrX_+_133334965 0.806 NM_001015877
NM_032335
NM_032458
PHF6


PHD finger protein 6


chr2_-_128138435 0.797 NM_017980
LIMS2
LIM and senescent cell antigen-like domains 2
chr4_-_83569476 0.788 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr10_-_97311084 0.784 NM_015385
NM_024991
SORBS1

sorbin and SH3 domain containing 1

chr5_-_64813459 0.782 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr5_+_79651545 0.774 NM_032567
SPZ1
spermatogenic leucine zipper 1
chr4_-_185632610 0.774 NM_002199
IRF2
interferon regulatory factor 2
chr7_+_882704 0.770 NM_015949
GET4
golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr7_+_120756325 0.765 NM_057168
WNT16
wingless-type MMTV integration site family, member 16
chrX_+_18353623 0.761 NM_003159
CDKL5
cyclin-dependent kinase-like 5
chr3_+_67131416 0.755 NM_032505
KBTBD8
kelch repeat and BTB (POZ) domain containing 8
chr11_-_78829342 0.747 NM_001098816
ODZ4
odz, odd Oz/ten-m homolog 4 (Drosophila)
chr8_-_70907957 0.739 NM_001146009
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr6_-_166502119 0.739 NM_003181
T
T, brachyury homolog (mouse)
chr5_+_140835788 0.738 PCDHGC3
protocadherin gamma subfamily C, 3
chr11_-_64247230 0.731 NM_015080
NM_138732
NRXN2

neurexin 2

chr11_+_18676857 0.719 TMEM86A
transmembrane protein 86A
chrX_+_41078787 0.719 DDX3X
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
chr15_-_43457916 0.718 GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr13_-_100125028 0.715 TMTC4
transmembrane and tetratricopeptide repeat containing 4
chr11_+_18676913 0.702 NM_153347
TMEM86A
transmembrane protein 86A
chr5_+_177564139 0.701 HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr7_+_76589869 0.701 NM_020879
CCDC146
coiled-coil domain containing 146
chr15_-_41000100 0.700 NM_173500
TTBK2
tau tubulin kinase 2
chr14_-_50631407 0.697 TRIM9
tripartite motif containing 9
chr11_-_6418705 0.697 NM_000613
HPX
hemopexin
chr3_+_123817151 0.693 NM_152615
PARP15
poly (ADP-ribose) polymerase family, member 15
chr7_+_148613304 0.690 LOC155060
AI894139 pseudogene
chr11_+_13646839 0.689 FAR1
fatty acyl CoA reductase 1
chrX_+_49013243 0.682 NM_001184745
NM_033215
PPP1R3F

protein phosphatase 1, regulatory (inhibitor) subunit 3F

chr8_-_120033240 0.679 NM_002546
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr1_-_210070736 0.678 NM_014873
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr8_-_22606653 0.677 NM_004430
EGR3
early growth response 3
chr1_+_54880014 0.676 NM_001039464
HEATR8-TTC4
HEATR8
HEATR8-TTC4 read-through transcript
HEAT repeat containing 8
chr11_-_71501385 0.674 NM_014042
C11orf51
chromosome 11 open reading frame 51
chr3_-_49732062 0.672 NM_198722
AMIGO3
adhesion molecule with Ig-like domain 3
chr9_+_123501186 0.669 DAB2IP
DAB2 interacting protein
chr3_+_50272648 0.663


chr5_+_76047536 0.659 NM_001992
F2R
coagulation factor II (thrombin) receptor
chr22_+_42900168 0.655 NM_001137605
PARVG
parvin, gamma
chr3_-_88190737 0.652 NM_001008390
NM_003663
CGGBP1

CGG triplet repeat binding protein 1

chr5_+_175725050 0.650 NM_173664
ARL10
ADP-ribosylation factor-like 10
chr12_-_98072602 0.650 NM_020140
NM_181670
ANKS1B

ankyrin repeat and sterile alpha motif domain containing 1B

chr11_+_45825532 0.648 NM_021117
CRY2
cryptochrome 2 (photolyase-like)
chr11_-_60880799 0.647 NM_001161452
CYBASC3
cytochrome b, ascorbate dependent 3
chr7_-_5535432 0.646 ACTB
actin, beta
chr5_-_124108672 0.641 NM_020747
ZNF608
zinc finger protein 608
chr4_-_113656762 0.640 NM_024019
NEUROG2
neurogenin 2
chr12_+_107433179 0.639 NM_007076
FICD
FIC domain containing
chr7_+_129497637 0.636 KLHDC10
kelch domain containing 10
chr9_-_126945536 0.633 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr11_-_72057755 0.632 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr1_+_163780063 0.630 NM_001005214
LRRC52
leucine rich repeat containing 52
chr11_+_13646822 0.628 FAR1
fatty acyl CoA reductase 1
chr9_+_124742932 0.626 NM_012197
RABGAP1
RAB GTPase activating protein 1
chr5_-_168660293 0.618 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr22_-_22511173 0.617 NM_001002862
NM_001135751
NM_198440
DERL3


Der1-like domain family, member 3


chr4_-_40553838 0.614 NM_001166051
NM_001166052
NM_001166053
NM_001166054
APBB2



amyloid beta (A4) precursor protein-binding, family B, member 2



chr1_+_207668787 0.610 NM_001104548
LOC642587
NPC-A-5
chr8_+_67201684 0.608 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr7_-_44854092 0.608 H2AFV
H2A histone family, member V
chr17_-_59131210 0.604 NM_030576
LIMD2
LIM domain containing 2
chr1_-_153560532 0.603 NM_001039517
C1orf104
chromosome 1 open reading frame 104
chr3_+_49482474 0.602 NM_001165928
NM_001177634
NM_001177635
NM_001177636
NM_001177637
NM_001177638
NM_001177639
NM_001177640
NM_001177641
NM_001177642
NM_001177644
NM_004393
DAG1











dystroglycan 1 (dystrophin-associated glycoprotein 1)











chrX_-_83644054 0.602 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chrX_+_15428820 0.600 NM_203281
BMX
BMX non-receptor tyrosine kinase
chr5_+_177564102 0.596 NM_004499
NM_031266
HNRNPAB

heterogeneous nuclear ribonucleoprotein A/B

chr8_-_70908130 0.596 NM_001146008
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr12_-_6103945 0.595 NM_000552
VWF
von Willebrand factor
chr3_-_58175437 0.594 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr1_-_234096793 0.593


chr12_+_54904417 0.591 OBFC2B
oligonucleotide/oligosaccharide-binding fold containing 2B
chr3_-_69674412 0.590 FRMD4B
FERM domain containing 4B
chr15_-_32875040 0.589 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr11_+_6854431 0.588 NM_207186
OR10A4
olfactory receptor, family 10, subfamily A, member 4
chr5_+_102493155 0.587 NM_015216
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr13_+_45174446 0.587 NM_152719
SPERT
spermatid associated
chrX_+_12903145 0.586 NM_021109
NM_183049
TMSB4X
TMSL3
thymosin beta 4, X-linked
thymosin-like 3
chr17_-_53920699 0.580 NM_001080439
HSF5
heat shock transcription factor family member 5
chr4_-_146320243 0.579 NM_001102653
OTUD4
OTU domain containing 4
chr11_-_2863536 0.578 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr1_+_245720992 0.578 NM_001004698
OR2W5
olfactory receptor, family 2, subfamily W, member 5
chr3_+_190831909 0.576 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr5_+_112340326 0.570 NM_152624
DCP2
DCP2 decapping enzyme homolog (S. cerevisiae)
chr15_-_70277163 0.570 NM_001012642
GRAMD2
GRAM domain containing 2
chrX_-_145703940 0.566 NM_001144064
CXorf51
chromosome X open reading frame 51
chr11_-_117600918 0.565 NM_001098526
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chrX_+_136475979 0.562 NM_003413
ZIC3
Zic family member 3 (odd-paired homolog, Drosophila)
chr7_+_106897737 0.561 NM_005295
GPR22
G protein-coupled receptor 22
chr1_-_234096842 0.558 NM_000081
LYST
lysosomal trafficking regulator
chr11_+_51371857 0.557 NM_001004703
OR4C46
olfactory receptor, family 4, subfamily C, member 46
chr5_-_157011665 0.556


chr19_+_17281216 0.556 NM_024050
DDA1
DET1 and DDB1 associated 1
chr1_-_209915443 0.554 NM_002497
NEK2
NIMA (never in mitosis gene a)-related kinase 2
chr16_+_55373241 0.553 NUP93
nucleoporin 93kDa
chr1_-_38285033 0.552 NM_002699
POU3F1
POU class 3 homeobox 1
chr19_-_14089362 0.551 NM_002730
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr7_-_44854145 0.550 H2AFV
H2A histone family, member V
chr7_-_44854183 0.550 H2AFV
H2A histone family, member V
chr11_-_59139743 0.548 OSBP
oxysterol binding protein
chr19_+_16083549 0.548 RAB8A
RAB8A, member RAS oncogene family
chr7_+_123083096 0.543 NM_207163
LMOD2
leiomodin 2 (cardiac)
chr11_+_61943082 0.542 NM_003357
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr5_-_95323353 0.541 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr10_+_22765996 0.541 LOC100289455
hypothetical LOC100289455
chr3_+_9414533 0.540 SETD5
SET domain containing 5
chr6_-_46246543 0.539 NM_021572
ENPP5
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chr6_+_29799095 0.539 NM_001098478
NM_001098479
NM_018950
HLA-F


major histocompatibility complex, class I, F


chr17_-_39796649 0.539 NM_198475
FAM171A2
family with sequence similarity 171, member A2
chr19_+_40325993 0.537 NM_022006
FXYD7
FXYD domain containing ion transport regulator 7
chr14_+_102870431 0.537 EIF5
eukaryotic translation initiation factor 5
chr11_+_62893836 0.537 NM_080866
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr8_+_38950824 0.536 NM_153692
HTRA4
HtrA serine peptidase 4
chr20_+_29309127 0.535 NM_001037730
DEFB115
defensin, beta 115
chr11_+_67984758 0.534 NM_001164160
NM_001164161
NM_001164162
NM_001164163
NM_001164164
NM_018312
PPP6R3





protein phosphatase 6, regulatory subunit 3





chrX_+_145698993 0.532 NM_001144064
CXorf51
chromosome X open reading frame 51
chr17_-_25281143 0.529 NM_033389
SSH2
slingshot homolog 2 (Drosophila)
chr6_-_134680888 0.529 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr2_+_74279197 0.529 NM_006636
MTHFD2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr19_+_16083706 0.528 RAB8A
RAB8A, member RAS oncogene family
chr21_-_31175722 0.527 NM_175858
KRTAP11-1
keratin associated protein 11-1
chr3_+_1109619 0.525 NM_014461
CNTN6
contactin 6
chr11_-_16953135 0.524 RPL36A
ribosomal protein L36a
chr8_+_81560971 0.523 NM_001105539
NM_023929
ZBTB10

zinc finger and BTB domain containing 10

chr11_-_66482366 0.523 NM_000920
NM_001040716
PC

pyruvate carboxylase

chr17_+_73511843 0.521 NM_001142640
NM_018996
TNRC6C

trinucleotide repeat containing 6C

chr19_-_14089560 0.517 PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr21_-_31853160 0.516 NM_003253
TIAM1
T-cell lymphoma invasion and metastasis 1
chr17_-_8034217 0.512 NM_017622
C17orf59
chromosome 17 open reading frame 59
chr2_-_171631728 0.512 NM_001136555
TLK1
tousled-like kinase 1
chr5_+_65927895 0.511 NM_001164664
NM_198828
MAST4

microtubule associated serine/threonine kinase family member 4

chr5_-_136862317 0.511 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr7_+_129497572 0.508 NM_014997
KLHDC10
kelch domain containing 10
chr15_+_81907176 0.508 SH3GL3
SH3-domain GRB2-like 3
chr7_-_122627235 0.507 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr3_-_47180417 0.507 NM_014159
SETD2
SET domain containing 2
chr1_-_25164061 0.503 NM_001031680
RUNX3
runt-related transcription factor 3
chr19_+_10626106 0.498 ILF3
interleukin enhancer binding factor 3, 90kDa
chrX_-_1470862 0.498 NM_001636
SLC25A6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr12_-_67012303 0.498 NM_017440
NM_020128
MDM1

Mdm1 nuclear protein homolog (mouse)

chr2_-_37752731 0.495 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr14_+_102870301 0.495 EIF5
eukaryotic translation initiation factor 5
chr12_+_47658502 0.494 NM_005430
WNT1
wingless-type MMTV integration site family, member 1
chr4_-_113777569 0.491 NM_018392
C4orf21
chromosome 4 open reading frame 21
chr1_-_195382189 0.490 NM_018136
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr9_+_90193807 0.488 SPIN1
spindlin 1
chr13_-_100125103 0.486 NM_001079669
NM_032813
TMTC4

transmembrane and tetratricopeptide repeat containing 4

chr7_-_99899829 0.486 NM_001004323
C7orf61
chromosome 7 open reading frame 61
chr4_+_113777568 0.485 NM_016648
LARP7
La ribonucleoprotein domain family, member 7
chr17_-_30470976 0.485 NM_001142571
NM_002878
NM_133629
RAD51L3


RAD51-like 3 (S. cerevisiae)


chr19_+_17281374 0.485 DDA1
DET1 and DDB1 associated 1
chr17_-_30470745 0.484 RAD51L3
RAD51-like 3 (S. cerevisiae)
chr12_-_10953427 0.483 NM_023920
TAS2R13
taste receptor, type 2, member 13
chr13_+_41744255 0.483 NM_016248
AKAP11
A kinase (PRKA) anchor protein 11
chr11_-_33139449 0.482 NM_001033505
NM_001033506
NM_001326
CSTF3


cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa


chr7_-_44854188 0.481 H2AFV
H2A histone family, member V
chr13_+_97426713 0.481 IPO5
importin 5

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.37 3.99e-04 GO:0007399 nervous system development
1.16 1.21e-03 GO:0032501 multicellular organismal process
1.68 2.35e-03 GO:0007608 sensory perception of smell
1.57 1.30e-02 GO:0007417 central nervous system development
1.57 2.23e-02 GO:0007606 sensory perception of chemical stimulus
1.40 2.98e-02 GO:0048468 cell development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 8.99e-03 GO:0005634 nucleus

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.68 1.13e-03 GO:0004984 olfactory receptor activity