Motif ID: SOX5.p2

Z-value: 1.332


Transcription factors associated with SOX5.p2:

Gene SymbolEntrez IDGene Name
SOX5 6660 SRY (sex determining region Y)-box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX5chr12_-_236287740.361.8e-01Click!


Activity profile for motif SOX5.p2.

activity profile for motif SOX5.p2


Sorted Z-values histogram for motif SOX5.p2

Sorted Z-values for motif SOX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_110968594 2.850 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr11_-_16380967 2.254 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr3_-_150422474 1.990 NM_000096
CP
ceruloplasmin (ferroxidase)
chr17_-_1195096 1.852 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr3_+_88270951 1.739 NM_018293
ZNF654
zinc finger protein 654
chr14_-_22974707 1.670 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr7_-_11838260 1.416 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr4_-_105635499 1.385 CXXC4
CXXC finger protein 4
chr1_+_154855709 1.278 NM_021817
HAPLN2
hyaluronan and proteoglycan link protein 2
chr3_-_150533948 1.276 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr14_-_106184988 1.274 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr12_-_10453409 1.241 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 read-through transcript
killer cell lectin-like receptor subfamily C, member 4
chr11_-_55460451 1.216 NM_006637
OR5I1
olfactory receptor, family 5, subfamily I, member 1
chr16_+_55373241 1.163 NUP93
nucleoporin 93kDa
chr10_-_32707549 1.159 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr4_-_101658094 1.108 NM_001159694
NM_016242
EMCN

endomucin

chr1_+_50344550 1.098 NM_001144775
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr6_-_135312899 1.083 NM_001193480
NM_022568
NM_170771
ALDH8A1


aldehyde dehydrogenase 8 family, member A1


chr7_-_26198673 1.051 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr2_-_215953818 1.004 FN1
fibronectin 1
chr2_+_228386800 0.997 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr1_-_150564302 0.988 NM_002016
FLG
filaggrin
chr10_-_62002672 0.958 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr4_+_113437947 0.957 NM_001102406
NM_025144
ALPK1

alpha-kinase 1

chr1_-_51660328 0.918 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr4_+_53975597 0.893 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr2_+_169631777 0.869 NM_199204
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr2_+_143351536 0.863 NM_001032998
NM_003937
KYNU

kynureninase

chr21_-_36870736 0.836 NM_001146077
CLDN14
claudin 14
chr3_-_69212192 0.802 NM_003968
NM_198195
UBA3

ubiquitin-like modifier activating enzyme 3

chr2_-_174475528 0.795


chr1_-_230717850 0.776 NM_020808
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr5_-_111340421 0.770 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr2_-_21087435 0.768 APOB
apolipoprotein B (including Ag(x) antigen)
chr4_-_170314382 0.762 SH3RF1
SH3 domain containing ring finger 1
chr3_+_173954940 0.762 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chr3_-_48729593 0.737 NM_001005909
NM_001005910
NM_001005911
NM_001146178
NM_001146179
NM_001190316
NM_001190317
NM_016291
IP6K2







inositol hexakisphosphate kinase 2







chr2_+_211166323 0.729 NM_001122634
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr3_+_173043832 0.728 NM_001164436
TMEM212
transmembrane protein 212
chr14_-_93493519 0.724 NM_016150
ASB2
ankyrin repeat and SOCS box containing 2
chr5_+_140227951 0.721 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr3_-_121065112 0.718


chr1_-_49014993 0.713 NM_024603
BEND5
BEN domain containing 5
chr2_+_167468220 0.712 NM_001079810
NM_152381
XIRP2

xin actin-binding repeat containing 2

chr15_+_47502666 0.711 NM_002009
FGF7
fibroblast growth factor 7
chr1_+_116727514 0.711 NM_001160234
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr3_+_190831909 0.708 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr17_+_3047559 0.705 NM_012352
OR1A2
olfactory receptor, family 1, subfamily A, member 2
chr20_-_7869068 0.703 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr2_-_56266408 0.694 LOC100129434
hypothetical LOC100129434
chr2_+_166137091 0.692 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr10_-_56230953 0.684 NM_001142763
NM_001142764
NM_001142765
NM_001142766
NM_001142767
NM_001142768
NM_001142769
NM_001142770
NM_001142771
NM_001142772
NM_001142773
NM_033056
PCDH15











protocadherin-related 15











chr6_+_29902734 0.680 NM_002127
HLA-G
major histocompatibility complex, class I, G
chr12_-_10893318 0.679 NM_007244
PRR4
proline rich 4 (lacrimal)
chr15_-_39195621 0.668 NM_017553
INO80
INO80 homolog (S. cerevisiae)
chr12_-_11354620 0.654 NM_002723
PRB4
proline-rich protein BstNI subfamily 4
chr9_-_4142182 0.652 NM_152629
GLIS3
GLIS family zinc finger 3
chr3_+_44665220 0.646 NM_003420
ZNF35
zinc finger protein 35
chr12_-_101115677 0.639 NM_002674
PMCH
pro-melanin-concentrating hormone
chr2_-_225073357 0.636 CUL3
cullin 3
chr8_-_59575249 0.635 NM_000780
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr4_+_71418886 0.627 NM_212557
AMTN
amelotin
chr17_-_53847937 0.619 RNF43
ring finger protein 43
chr4_-_64957595 0.606 NM_001010874
TECRL
trans-2,3-enoyl-CoA reductase-like
chr6_-_128263868 0.605 NM_001010923
NM_001164685
THEMIS

thymocyte selection associated

chr1_-_152431175 0.599 NM_152263
TPM3
tropomyosin 3
chr9_-_28709302 0.596 NM_152570
LINGO2
leucine rich repeat and Ig domain containing 2
chr8_+_85258007 0.589 NM_001100392
NM_001100393
RALYL

RALY RNA binding protein-like

chr4_-_68766392 0.589 NM_001129907
TMPRSS11BNL
TMPRSS11B N terminal-like
chr9_+_109131814 0.586 RAD23B
RAD23 homolog B (S. cerevisiae)
chr17_-_46479127 0.585 SPAG9
sperm associated antigen 9
chr5_+_140573692 0.581 NM_018933
PCDHB13
protocadherin beta 13
chr10_+_94584449 0.580 NM_001013848
EXOC6
exocyst complex component 6
chr8_-_38324809 0.579 WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
chr3_-_101077605 0.578 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr20_-_45418818 0.573 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr7_-_84589182 0.571 NM_152754
SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr16_-_20323533 0.569 NM_174924
PDILT
protein disulfide isomerase-like, testis expressed
chr4_+_71096830 0.567 NM_017855
ODAM
odontogenic, ameloblast asssociated
chr7_+_50314801 0.566 NM_006060
IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr12_-_11399776 0.564 NM_005039
NM_199353
NM_199354
PRB1


proline-rich protein BstNI subfamily 1


chr3_-_56673113 0.564 NM_015224
C3orf63
chromosome 3 open reading frame 63
chr18_-_55136673 0.562 NM_181654
CPLX4
complexin 4
chr15_+_22751162 0.561 NM_003097
NM_022804
NM_005678
SNRPN
SNURF

small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame

chr2_+_114935623 0.550 NM_001178036
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr17_-_36451189 0.538 NM_030967
KRTAP1-3
KRTAP1-1
keratin associated protein 1-3
keratin associated protein 1-1
chr2_+_143603439 0.535 ARHGAP15
Rho GTPase activating protein 15
chr3_+_142587973 0.533


chr3_+_85858321 0.528 NM_153184
CADM2
cell adhesion molecule 2
chr14_+_19318240 0.526 NM_001005500
OR4M1
olfactory receptor, family 4, subfamily M, member 1
chr2_+_191009265 0.525 MFSD6
major facilitator superfamily domain containing 6
chr6_-_48186868 0.522 C6orf138
chromosome 6 open reading frame 138
chr3_-_129777618 0.522 NM_007354
C3orf27
chromosome 3 open reading frame 27
chr11_-_121492010 0.522 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr20_-_14266200 0.518 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr12_+_54172413 0.517 NM_001005519
OR6C68
olfactory receptor, family 6, subfamily C, member 68
chr14_+_19414230 0.511 NM_001005501
OR4K2
olfactory receptor, family 4, subfamily K, member 2
chr17_+_73511843 0.510 NM_001142640
NM_018996
TNRC6C

trinucleotide repeat containing 6C

chr2_-_162717159 0.509 NM_002054
GCG
glucagon
chr12_+_111980044 0.509 NM_004416
DTX1
deltex homolog 1 (Drosophila)
chr10_-_74863303 0.505 NM_001024593
ZMYND17
zinc finger, MYND-type containing 17
chr5_-_14706486 0.503


chr11_-_123414917 0.503 NM_001004463
OR10G7
olfactory receptor, family 10, subfamily G, member 7
chr5_-_64813459 0.503 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr6_-_76838944 0.502 NM_001563
IMPG1
interphotoreceptor matrix proteoglycan 1
chr6_-_111995213 0.501 NM_001164283
TRAF3IP2
TRAF3 interacting protein 2
chr2_+_143603368 0.500 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr7_+_106897737 0.495 NM_005295
GPR22
G protein-coupled receptor 22
chr14_-_19843969 0.494 NM_138376
TTC5
tetratricopeptide repeat domain 5
chr10_+_96433240 0.494 NM_000772
NM_001128925
CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

chr14_-_94669547 0.492 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr12_+_8499788 0.487 NM_001007033
CLEC6A
C-type lectin domain family 6, member A
chr3_+_82117978 0.485


chr1_-_7998265 0.482 ERRFI1
ERBB receptor feedback inhibitor 1
chr9_-_4656665 0.482 NM_001039395
C9orf68
chromosome 9 open reading frame 68
chr14_-_106202262 0.479 IGLJ3
IGHA1
immunoglobulin lambda joining 3
immunoglobulin heavy constant alpha 1
chr11_-_92570626 0.477


chr1_-_74971679 0.476 NM_001130042
NM_001130043
NM_001134759
NM_001889
CRYZ



crystallin, zeta (quinone reductase)



chr1_+_148603208 0.476 RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr2_-_97775300 0.475 TMEM131
transmembrane protein 131
chr12_-_11066436 0.474 NM_176888
TAS2R19
taste receptor, type 2, member 19
chr6_-_24491498 0.474 NM_001195610
DCDC2
doublecortin domain containing 2
chr17_+_31415752 0.469 NM_002988
CCL18
chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
chr4_+_1375339 0.464 NM_175918
CRIPAK
cysteine-rich PAK1 inhibitor
chr7_-_22518200 0.463 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr5_-_13997588 0.460 NM_001369
DNAH5
dynein, axonemal, heavy chain 5
chr13_+_23742846 0.455 SPATA13
spermatogenesis associated 13
chrX_-_50573759 0.451 NM_020717
SHROOM4
shroom family member 4
chr5_-_75505874 0.449 RAP1BL
RAP1B, member of RAS oncogene family pseudogene
chr11_+_4564596 0.447 NM_001005170
OR52I2
olfactory receptor, family 52, subfamily I, member 2
chr6_+_100161370 0.447 NM_021620
PRDM13
PR domain containing 13
chr6_+_114285209 0.445 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr3_+_46591048 0.444 NM_001174136
TDGF1
teratocarcinoma-derived growth factor 1
chr1_-_195302973 0.442 NM_001994
F13B
coagulation factor XIII, B polypeptide
chr8_-_82769761 0.437 NM_001010893
SLC10A5
solute carrier family 10 (sodium/bile acid cotransporter family), member 5
chr13_-_32678142 0.435 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr6_-_116488458 0.432 NM_002031
FRK
fyn-related kinase
chr5_+_140835788 0.430 PCDHGC3
protocadherin gamma subfamily C, 3
chr14_+_38653177 0.429 NM_001009182
NM_001009183
NM_003616
SIP1


survival of motor neuron protein interacting protein 1


chr9_+_22103542 0.428 CDKN2B-AS1
CDKN2B antisense RNA 1 (non-protein coding)
chr8_-_72437020 0.427 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr6_-_128883125 0.427 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr11_+_5862076 0.425 NM_001005165
OR52E4
olfactory receptor, family 52, subfamily E, member 4
chr15_+_71953020 0.425 NM_153356
TBC1D21
TBC1 domain family, member 21
chr7_+_54577512 0.424 NM_182546
VSTM2A
V-set and transmembrane domain containing 2A
chr14_-_19843918 0.424 TTC5
tetratricopeptide repeat domain 5
chr14_+_38772870 0.423 NM_054024
MIA2
melanoma inhibitory activity 2
chr11_+_54891935 0.423 NM_001005275
OR4A15
olfactory receptor, family 4, subfamily A, member 15
chr2_-_165768798 0.422 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chr8_+_24207524 0.422 NM_014265
NM_021777
ADAM28

ADAM metallopeptidase domain 28

chr3_+_99699137 0.417 NM_001004737
OR5K2
olfactory receptor, family 5, subfamily K, member 2
chr13_+_107753764 0.417


chr17_+_58625086 0.417 TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr6_-_130578110 0.417 NM_152552
SAMD3
sterile alpha motif domain containing 3
chr11_+_9552809 0.415 NM_001143976
WEE1
WEE1 homolog (S. pombe)
chr2_-_128138435 0.414 NM_017980
LIMS2
LIM and senescent cell antigen-like domains 2
chr13_+_77213295 0.414 NM_144595
SLAIN1
SLAIN motif family, member 1
chr21_-_30583702 0.413 NM_001128598
KRTAP25-1
keratin associated protein 25-1
chr16_+_68284252 0.413 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr7_+_156128431 0.412 NM_001184997
RNF32
ring finger protein 32
chr11_-_123130435 0.411 NM_001005188
OR6X1
olfactory receptor, family 6, subfamily X, member 1
chr8_+_24297742 0.409 NM_001145271
NM_001145272
NM_014479
ADAMDEC1


ADAM-like, decysin 1


chr8_+_67201684 0.406 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr2_-_179380301 0.405 NM_003319
NM_133378
NM_133379
NM_133432
NM_133437
TTN




titin




chr15_-_39195701 0.404 INO80
INO80 homolog (S. cerevisiae)
chr9_+_115265827 0.403 NM_017790
RGS3
regulator of G-protein signaling 3
chr19_+_12810258 0.403 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr2_-_180319013 0.402 NM_001113397
ZNF385B
zinc finger protein 385B
chr7_-_105009160 0.401 EFCAB10
EF-hand calcium binding domain 10
chr5_+_140835727 0.400 NM_002588
NM_032402
NM_032403
PCDHGC3


protocadherin gamma subfamily C, 3


chr1_+_84402962 0.399 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chrX_+_15435351 0.399 NM_001721
BMX
BMX non-receptor tyrosine kinase
chr10_-_98326435 0.397 TM9SF3
transmembrane 9 superfamily member 3
chr2_-_236837726 0.396 NM_212556
ASB18
ankyrin repeat and SOCS box containing 18
chr3_+_99484421 0.394 NM_001005482
OR5H2
olfactory receptor, family 5, subfamily H, member 2
chr2_-_178461710 0.394 NM_001077196
PDE11A
phosphodiesterase 11A
chr1_+_176577228 0.391 NM_004841
RASAL2
RAS protein activator like 2
chr11_-_35398077 0.391 NM_001195728
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr4_+_124537334 0.390 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr2_+_108637698 0.388 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chr11_+_5925152 0.388 NM_001003443
OR56A3
olfactory receptor, family 56, subfamily A, member 3
chr2_-_180135559 0.386 NM_001113398
ZNF385B
zinc finger protein 385B
chr19_-_6230797 0.386


chr3_-_147805715 0.386 PLSCR5
phospholipid scramblase family, member 5
chr9_+_134884627 0.385 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr2_+_108230082 0.384 NM_001008743
SULT1C3
sulfotransferase family, cytosolic, 1C, member 3
chr2_+_211129567 0.382 NM_001875
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chrX_-_116991728 0.382 NM_033495
NM_001168300
KLHL13

kelch-like 13 (Drosophila)

chr3_-_113701073 0.379 NM_001085357
NM_181780
BTLA

B and T lymphocyte associated

chr18_-_49944986 0.379 MBD2
methyl-CpG binding domain protein 2
chr3_+_186529376 0.377 MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr14_-_87859284 0.375 NM_138317
KCNK10
potassium channel, subfamily K, member 10
chr10_-_98311813 0.373 TM9SF3
transmembrane 9 superfamily member 3
chr6_-_52818851 0.373 NM_153699
GSTA5
glutathione S-transferase alpha 5
chr12_-_368517 0.372 KDM5A
lysine (K)-specific demethylase 5A
chr16_+_48857962 0.372 ADCY7
adenylate cyclase 7
chr4_-_68432293 0.370 NM_004262
TMPRSS11D
transmembrane protease, serine 11D
chr5_-_38631263 0.370 NM_002310
LIFR
leukemia inhibitory factor receptor alpha
chr11_-_51269023 0.368 NM_001005272
OR4A5
olfactory receptor, family 4, subfamily A, member 5
chr5_-_147266257 0.367 NM_206966
C5orf46
chromosome 5 open reading frame 46

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.05 5.85e-07 GO:0007608 sensory perception of smell
1.97 1.05e-06 GO:0007606 sensory perception of chemical stimulus
1.18 8.49e-05 GO:0050896 response to stimulus
1.53 5.03e-03 GO:0007600 sensory perception
1.32 2.50e-02 GO:0003008 system process
1.90 4.65e-02 GO:0030036 actin cytoskeleton organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 4.93e-03 GO:0071944 cell periphery
1.18 4.94e-03 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.07 1.89e-07 GO:0004984 olfactory receptor activity
1.50 2.55e-03 GO:0004930 G-protein coupled receptor activity