Motif ID: SPI1.p2

Z-value: 1.396


Transcription factors associated with SPI1.p2:

Gene SymbolEntrez IDGene Name
SPI1 6688 spleen focus forming virus (SFFV) proviral integration oncogene spi1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPI1chr11_-_473564790.332.1e-01Click!


Activity profile for motif SPI1.p2.

activity profile for motif SPI1.p2


Sorted Z-values histogram for motif SPI1.p2

Sorted Z-values for motif SPI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_35586950 1.416 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr12_-_53071285 1.225 NM_001130967
NM_001130968
ZNF385A

zinc finger protein 385A

chrX_-_47374187 1.111 NM_001145252
CFP
complement factor properdin
chr5_-_88215034 0.915 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr1_+_159899528 0.872 NM_001002273
NM_001002274
NM_001002275
NM_001190828
NM_004001
FCGR2B




FCGR2C
Fc fragment of IgG, low affinity IIb, receptor (CD32)




Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr19_+_54068373 0.828 PPP1R15A
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr22_-_18484428 0.803 TRMT2A
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr12_-_55929189 0.753


chr11_-_46099531 0.753 NM_001101802
NM_016621
PHF21A

PHD finger protein 21A

chr10_+_70553993 0.732 VPS26A
vacuolar protein sorting 26 homolog A (S. pombe)
chr1_-_32574185 0.724 NM_023009
MARCKSL1
MARCKS-like 1
chrX_+_134482387 0.713 DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr8_+_126511739 0.695 NM_025195
TRIB1
tribbles homolog 1 (Drosophila)
chr11_+_47386621 0.674 NM_001128225
NM_152264
SLC39A13

solute carrier family 39 (zinc transporter), member 13

chr3_+_145173329 0.666 NM_173552
C3orf58
chromosome 3 open reading frame 58
chr16_-_87570716 0.665 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr22_-_30018329 0.662 NM_001135911
NM_052880
PIK3IP1

phosphoinositide-3-kinase interacting protein 1

chr11_+_47386707 0.660 SLC39A13
solute carrier family 39 (zinc transporter), member 13
chr17_-_44058612 0.647 NM_024017
HOXB9
homeobox B9
chr1_+_233558375 0.645 NM_001037277
NM_004837
GGPS1

geranylgeranyl diphosphate synthase 1

chr12_+_50592379 0.645 NM_001077401
ACVRL1
activin A receptor type II-like 1
chr12_+_25096755 0.641 LRMP
lymphoid-restricted membrane protein
chr10_+_70745615 0.609 NM_033496
HK1
hexokinase 1
chr17_-_55824083 0.606 USP32
ubiquitin specific peptidase 32
chr2_+_108604111 0.597 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chr19_-_55008172 0.595 NM_001171937
NM_025129
FUZ

fuzzy homolog (Drosophila)

chr1_-_17318452 0.581 NM_007365
PADI2
peptidyl arginine deiminase, type II
chr21_+_25856311 0.574 MIR155HG
MIR155 host gene (non-protein coding)
chr17_+_26446082 0.573 NF1
neurofibromin 1
chrX_+_134482212 0.556 NM_182540
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr17_+_24742068 0.552 NM_020791
TAOK1
TAO kinase 1
chr17_+_22645268 0.552 WSB1
WD repeat and SOCS box containing 1
chr1_-_52791309 0.551 NM_001009881
NM_015269
ZCCHC11

zinc finger, CCHC domain containing 11

chr10_-_121292139 0.549 NM_001005339
RGS10
regulator of G-protein signaling 10
chr16_+_80086454 0.547 NM_030629
CMIP
c-Maf-inducing protein
chr3_+_145173585 0.544 C3orf58
chromosome 3 open reading frame 58
chr15_-_35180656 0.530 NM_002399
MEIS2
Meis homeobox 2
chr13_-_107317460 0.529 NM_001080396
FAM155A
family with sequence similarity 155, member A
chr5_+_75734759 0.528 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr19_-_46550788 0.525 TGFB1
transforming growth factor, beta 1
chr6_-_43703024 0.524 GTPBP2
GTP binding protein 2
chr12_+_81605289 0.518 TMTC2
transmembrane and tetratricopeptide repeat containing 2
chr12_+_25096472 0.513 NM_006152
LRMP
lymphoid-restricted membrane protein
chr1_+_149309703 0.510 NM_144618
GABPB2
GA binding protein transcription factor, beta subunit 2
chr3_-_15348811 0.507 SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr12_+_119609341 0.493 MLEC
malectin
chr6_-_30762385 0.490 KIAA1949
KIAA1949
chr6_-_43703057 0.488 GTPBP2
GTP binding protein 2
chrX_-_47374647 0.484 NM_002621
CFP
complement factor properdin
chr3_+_140148765 0.483 NM_001040061
C3orf72
chromosome 3 open reading frame 72
chr2_+_130846263 0.475 PTPN18
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chrX_-_153698930 0.475 HMGN1P37
high-mobility group nucleosome binding domain 1 pseudogene 37
chr10_+_70553983 0.475 VPS26A
vacuolar protein sorting 26 homolog A (S. pombe)
chr15_-_35177664 0.474 NM_172315
MEIS2
Meis homeobox 2
chr19_+_54068300 0.474 PPP1R15A
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr10_+_70553949 0.474 VPS26A
vacuolar protein sorting 26 homolog A (S. pombe)
chr1_+_209499349 0.468 RCOR3
REST corepressor 3
chr1_-_159368834 0.467 NM_001039712
DEDD
death effector domain containing
chr9_-_129869211 0.467 NM_197956
NAIF1
nuclear apoptosis inducing factor 1
chr10_+_70553962 0.467 VPS26A
vacuolar protein sorting 26 homolog A (S. pombe)
chr12_+_119609305 0.466 NM_014730
MLEC
malectin
chr17_+_1906262 0.457 NM_001098202
HIC1
hypermethylated in cancer 1
chr11_-_76800525 0.456 PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr4_-_140696740 0.455 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr7_-_120285364 0.455 NM_012338
TSPAN12
tetraspanin 12
chr3_-_15349086 0.455 NM_004844
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr1_+_168767864 0.452 NM_001146039
NM_152281
GORAB

golgin, RAB6-interacting

chr9_+_129588179 0.450 CDK9
cyclin-dependent kinase 9
chrX_-_102828238 0.447 NM_001142418
NM_001142423
NM_001142424
NM_001142425
NM_001142426
NM_001142429
NM_001142430
NM_012286
MORF4L2







mortality factor 4 like 2







chr11_+_44044304 0.446 NM_001127219
NM_032592
ACCS

1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)

chr10_+_70553862 0.439 NM_001035260
NM_004896
VPS26A

vacuolar protein sorting 26 homolog A (S. pombe)

chrX_-_53327473 0.436 NM_015075
IQSEC2
IQ motif and Sec7 domain 2
chr19_+_41085221 0.434 NM_001007469
NM_014266
HCST

hematopoietic cell signal transducer

chr6_-_32265489 0.433 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr3_-_140148671 0.431 NM_023067
FOXL2
forkhead box L2
chr20_-_3713509 0.426 CENPB
centromere protein B, 80kDa
chr18_+_2836979 0.422 NM_032048
EMILIN2
elastin microfibril interfacer 2
chr12_-_51887266 0.422 NM_000889
ITGB7
integrin, beta 7
chr7_-_150283794 0.418 NM_172057
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr6_+_73388713 0.414 KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr11_-_62251361 0.412 NM_001079559
HNRNPUL2
heterogeneous nuclear ribonucleoprotein U-like 2
chr17_-_4113777 0.409 NM_016376
NM_020740
ANKFY1

ankyrin repeat and FYVE domain containing 1

chr1_-_158182006 0.408 NM_001135050
NM_020789
IGSF9

immunoglobulin superfamily, member 9

chr11_-_1975646 0.408 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr22_+_19601723 0.407 CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr6_-_30760413 0.405 KIAA1949
KIAA1949
chr1_-_183553083 0.403 NM_006469
IVNS1ABP
influenza virus NS1A binding protein
chr1_+_154351200 0.398 LMNA
lamin A/C
chr10_+_71908535 0.397 NM_014431
KIAA1274
KIAA1274
chr22_+_19601940 0.397 CRKL
v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr1_+_100590619 0.395 CDC14A
CDC14 cell division cycle 14 homolog A (S. cerevisiae)
chr15_-_76313896 0.392 NM_015162
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr17_+_69721095 0.392 NM_032646
TTYH2
tweety homolog 2 (Drosophila)
chr19_-_48866111 0.392 NM_001005376
NM_001005377
NM_002659
PLAUR


plasminogen activator, urokinase receptor


chr1_-_92124064 0.392 TGFBR3
transforming growth factor, beta receptor III
chr19_+_10258642 0.391 NM_001039132
NM_001544
NM_022377
ICAM4


intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)


chr12_-_116984275 0.391 WSB2
WD repeat and SOCS box containing 2
chr3_-_159306532 0.391 NM_001163678
NM_003030
NM_006884
SHOX2


short stature homeobox 2


chr17_+_26060617 0.390


chr3_+_195889845 0.388 FAM43A
family with sequence similarity 43, member A
chr19_-_53516962 0.387 CCDC114
coiled-coil domain containing 114
chr1_-_21982192 0.387 USP48
ubiquitin specific peptidase 48
chr1_-_27353987 0.387 NM_003047
SLC9A1
solute carrier family 9 (sodium/hydrogen exchanger), member 1
chr1_+_209499478 0.386 RCOR3
REST corepressor 3
chr6_-_32268267 0.384 GPSM3
G-protein signaling modulator 3
chr7_-_13996166 0.384 NM_001163147
NM_004956
ETV1

ets variant 1

chr17_+_35727998 0.383 NM_001145301
NM_001145302
RARA

retinoic acid receptor, alpha

chr2_+_37282516 0.383 LOC100505876
hypothetical LOC100505876
chr5_+_140780797 0.379 PCDHGA11
protocadherin gamma subfamily A, 11
chr3_-_107070400 0.376 NM_170662
CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr12_-_91063441 0.374 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr8_+_38763878 0.373 NM_001122824
NM_006283
TACC1

transforming, acidic coiled-coil containing protein 1

chr7_-_100077072 0.371 NM_003227
TFR2
transferrin receptor 2
chr3_-_151904408 0.368 NM_152394
FAM194A
family with sequence similarity 194, member A
chr1_+_172395277 0.366 RABGAP1L
RAB GTPase activating protein 1-like
chr6_-_32268615 0.363 GPSM3
G-protein signaling modulator 3
chr12_+_55018925 0.363 NM_016584
IL23A
interleukin 23, alpha subunit p19
chr10_-_25052549 0.361 NM_020824
ARHGAP21
Rho GTPase activating protein 21
chr2_-_104834344 0.360 LOC100506421
hypothetical LOC100506421
chr7_+_101715137 0.360 SH2B2
SH2B adaptor protein 2
chr11_+_58668827 0.359 NM_022074
NM_198847
FAM111A

family with sequence similarity 111, member A

chr17_-_31441390 0.359 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr7_+_101715110 0.358 NM_020979
SH2B2
SH2B adaptor protein 2
chr1_-_142535878 0.357 LOC100286793
FLJ39739
hypothetical LOC100286793
hypothetical FLJ39739
chrX_+_118776572 0.357 NM_001105576
ANKRD58
ankyrin repeat domain 58
chr13_+_110165329 0.357 NM_005537
ING1
inhibitor of growth family, member 1
chr19_+_47056102 0.357 RPS19
ribosomal protein S19
chr19_+_51804260 0.356 CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr19_-_3012138 0.355 AES
amino-terminal enhancer of split
chr10_+_102811542 0.355 KAZALD1
Kazal-type serine peptidase inhibitor domain 1
chr3_-_28365284 0.354 AZI2
5-azacytidine induced 2
chr1_-_21375939 0.354 NM_001198801
NM_001198802
EIF4G3

eukaryotic translation initiation factor 4 gamma, 3

chr7_-_44985202 0.353 NM_033054
MYO1G
myosin IG
chr6_-_136888771 0.353 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr12_-_56422120 0.352 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr1_+_209499355 0.351 RCOR3
REST corepressor 3
chr13_-_76358370 0.349 KCTD12
potassium channel tetramerisation domain containing 12
chr15_-_81146188 0.347 AP3B2
adaptor-related protein complex 3, beta 2 subunit
chr19_-_51058177 0.345 NM_004819
SYMPK
symplekin
chr11_+_64946820 0.343 NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr4_-_57217226 0.343 NM_001145459
NM_139211
HOPX

HOP homeobox

chr16_+_55777739 0.342 NM_133368
RSPRY1
ring finger and SPRY domain containing 1
chr11_-_64403712 0.341 EHD1
EH-domain containing 1
chr7_-_104440707 0.341 LOC100216545
hypothetical LOC100216545
chr15_-_54997964 0.340 LOC145783
hypothetical LOC145783
chr1_-_21982256 0.340 NM_001032730
NM_032236
USP48

ubiquitin specific peptidase 48

chr14_+_104238713 0.340 INF2
inverted formin, FH2 and WH2 domain containing
chr9_+_132990760 0.339 NM_005085
NUP214
nucleoporin 214kDa
chr1_+_154351162 0.337 LMNA
lamin A/C
chr14_+_74964672 0.337 NM_001135048
NM_130469
JDP2

Jun dimerization protein 2

chr11_+_64946848 0.336


chr1_-_243094233 0.335 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr7_-_44985175 0.334 MYO1G
myosin IG
chr9_+_132990834 0.333 NUP214
nucleoporin 214kDa
chr8_+_38763911 0.328 TACC1
transforming, acidic coiled-coil containing protein 1
chrX_-_138114100 0.327 FGF13
fibroblast growth factor 13
chr7_+_22733290 0.327 NM_000600
IL6
interleukin 6 (interferon, beta 2)
chr12_-_55791443 0.326 NM_001178078
NM_001178080
NM_001178081
NM_003153
STAT6



signal transducer and activator of transcription 6, interleukin-4 induced



chr1_-_159368985 0.325 DEDD
death effector domain containing
chr17_-_73640082 0.323 NM_007267
TMC6
transmembrane channel-like 6
chr7_-_5519831 0.322 NM_024963
FBXL18
F-box and leucine-rich repeat protein 18
chr1_-_243094431 0.322 NM_004501
NM_031844
HNRNPU

heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)

chr17_-_59363352 0.321 NM_000626
NM_001039933
NM_021602
CD79B


CD79b molecule, immunoglobulin-associated beta


chr7_-_44985084 0.318 MYO1G
myosin IG
chr10_+_70553945 0.317 VPS26A
vacuolar protein sorting 26 homolog A (S. pombe)
chr11_-_77806413 0.314 GAB2
GRB2-associated binding protein 2
chr1_-_243094414 0.313 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chrX_-_48818585 0.311 NM_007213
PRAF2
PRA1 domain family, member 2
chr12_-_51887318 0.311 ITGB7
integrin, beta 7
chr8_+_67505091 0.308 RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr10_-_119795663 0.308 NM_014904
RAB11FIP2
RAB11 family interacting protein 2 (class I)
chr9_+_129588125 0.307 NM_001261
CDK9
cyclin-dependent kinase 9
chr17_-_39630951 0.306 NM_001098833
NM_020218
ATXN7L3

ataxin 7-like 3

chr5_-_74098641 0.306 NM_032380
NM_170681
NM_170691
GFM2


G elongation factor, mitochondrial 2


chr1_+_43539239 0.303 NM_005424
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr1_+_32438788 0.303 NM_024296
CCDC28B
coiled-coil domain containing 28B
chr15_+_79080341 0.303 NM_022566
MESDC1
mesoderm development candidate 1
chr12_+_54672766 0.301 RAB5B
RAB5B, member RAS oncogene family
chr5_+_74098828 0.301 NM_014886
NSA2
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr15_+_65145215 0.298 SMAD3
SMAD family member 3
chr8_+_22493928 0.298 NM_176871
NM_198042
PDLIM2

PDZ and LIM domain 2 (mystique)

chr7_-_110989582 0.296 NM_032549
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr1_-_38097811 0.295 NM_005955
MTF1
metal-regulatory transcription factor 1
chr10_+_26767698 0.295 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr7_-_126680372 0.294 GRM8
glutamate receptor, metabotropic 8
chr15_+_88345612 0.293 NM_198526
ZNF710
zinc finger protein 710
chr12_+_53241365 0.293 NM_001165975
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr1_-_149298660 0.293 CDC42SE1
CDC42 small effector 1
chr6_-_137155295 0.293 MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr1_+_36169260 0.291 NM_024852
NM_177422
EIF2C3

eukaryotic translation initiation factor 2C, 3

chr9_-_132759045 0.291 NM_198180
QRFP
pyroglutamylated RFamide peptide
chr19_-_46626474 0.290 NM_198540
B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr22_-_18484695 0.290 TRMT2A
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr3_-_28365510 0.290 NM_001134432
NM_001134433
NM_022461
AZI2


5-azacytidine induced 2


chr1_-_149298676 0.289 CDC42SE1
CDC42 small effector 1
chr12_+_52696908 0.289 NM_014620
NM_153693
HOXC4
HOXC6
homeobox C4
homeobox C6
chr7_-_13995811 0.289 ETV1
ets variant 1
chr1_+_152566899 0.288 NM_020452
ATP8B2
ATPase, class I, type 8B, member 2
chr1_-_149298706 0.288 NM_001038707
NM_020239
CDC42SE1

CDC42 small effector 1

chr7_-_86686754 0.287 NM_024315
C7orf23
chromosome 7 open reading frame 23

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.19 3.22e-16 GO:0044260 cellular macromolecule metabolic process
1.18 8.65e-16 GO:0043170 macromolecule metabolic process
1.08 4.90e-14 GO:0009987 cellular process
1.13 2.09e-13 GO:0050794 regulation of cellular process
1.11 1.13e-10 GO:0050789 regulation of biological process
1.10 1.53e-10 GO:0065007 biological regulation
1.22 2.04e-09 GO:0044267 cellular protein metabolic process
1.22 3.45e-09 GO:0048522 positive regulation of cellular process
1.23 5.39e-09 GO:0048523 negative regulation of cellular process
1.12 6.33e-09 GO:0044238 primary metabolic process
1.22 6.40e-09 GO:0048519 negative regulation of biological process
1.20 1.07e-08 GO:0048518 positive regulation of biological process
1.24 2.44e-08 GO:0048583 regulation of response to stimulus
1.15 4.12e-08 GO:0051716 cellular response to stimulus
1.18 8.51e-08 GO:0019538 protein metabolic process
1.17 1.09e-07 GO:0007165 signal transduction
1.16 1.56e-07 GO:0031323 regulation of cellular metabolic process
1.24 1.99e-07 GO:0016070 RNA metabolic process
1.11 2.41e-07 GO:0044237 cellular metabolic process
1.16 2.65e-07 GO:0071840 cellular component organization or biogenesis
1.15 3.06e-07 GO:0019222 regulation of metabolic process
1.23 3.69e-07 GO:0006464 protein modification process
1.22 5.51e-07 GO:0043412 macromolecule modification
1.16 6.57e-07 GO:0016043 cellular component organization
1.23 9.50e-07 GO:0010467 gene expression
1.15 1.03e-06 GO:0023052 signaling
1.09 1.94e-06 GO:0008152 metabolic process
1.26 2.28e-06 GO:0009966 regulation of signal transduction
1.15 3.57e-06 GO:0080090 regulation of primary metabolic process
1.15 4.86e-06 GO:0060255 regulation of macromolecule metabolic process
1.19 6.55e-06 GO:0090304 nucleic acid metabolic process
1.17 7.68e-06 GO:0071841 cellular component organization or biogenesis at cellular level
1.17 1.20e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.17 1.47e-05 GO:0071842 cellular component organization at cellular level
1.22 1.86e-05 GO:0023051 regulation of signaling
1.41 3.38e-05 GO:0007599 hemostasis
1.24 3.76e-05 GO:0035556 intracellular signal transduction
1.28 5.37e-05 GO:0032268 regulation of cellular protein metabolic process
1.41 5.64e-05 GO:0007596 blood coagulation
1.41 5.64e-05 GO:0050817 coagulation
1.40 6.31e-05 GO:0001775 cell activation
1.38 7.19e-05 GO:0050878 regulation of body fluid levels
1.25 1.84e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.26 2.59e-04 GO:0043067 regulation of programmed cell death
1.26 2.84e-04 GO:0042981 regulation of apoptosis
1.36 2.86e-04 GO:0006928 cellular component movement
1.68 4.46e-04 GO:0050900 leukocyte migration
1.34 4.75e-04 GO:0009057 macromolecule catabolic process
1.20 5.38e-04 GO:0006996 organelle organization
1.33 5.56e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.25 5.62e-04 GO:0051246 regulation of protein metabolic process
1.25 5.89e-04 GO:0010941 regulation of cell death
1.24 6.80e-04 GO:0031325 positive regulation of cellular metabolic process
1.15 7.22e-04 GO:0010468 regulation of gene expression
1.23 7.98e-04 GO:0009893 positive regulation of metabolic process
1.34 8.21e-04 GO:0042060 wound healing
1.26 8.22e-04 GO:0009892 negative regulation of metabolic process
1.51 9.76e-04 GO:0016567 protein ubiquitination
1.40 1.37e-03 GO:0016477 cell migration
1.48 1.73e-03 GO:0032446 protein modification by small protein conjugation
1.26 2.12e-03 GO:0009611 response to wounding
1.15 2.73e-03 GO:0006950 response to stress
1.43 2.73e-03 GO:0070647 protein modification by small protein conjugation or removal
1.25 2.73e-03 GO:0032774 RNA biosynthetic process
1.22 2.77e-03 GO:0051641 cellular localization
1.26 3.38e-03 GO:0040011 locomotion
1.24 3.58e-03 GO:0010646 regulation of cell communication
1.34 4.10e-03 GO:0044265 cellular macromolecule catabolic process
1.25 4.41e-03 GO:0031324 negative regulation of cellular metabolic process
1.39 5.67e-03 GO:0010627 regulation of intracellular protein kinase cascade
1.14 6.03e-03 GO:0009889 regulation of biosynthetic process
1.25 6.66e-03 GO:0006351 transcription, DNA-dependent
1.35 7.15e-03 GO:0048870 cell motility
1.35 7.15e-03 GO:0051674 localization of cell
1.14 7.75e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.14 7.95e-03 GO:0031326 regulation of cellular biosynthetic process
1.26 8.00e-03 GO:0031399 regulation of protein modification process
1.30 9.25e-03 GO:0051726 regulation of cell cycle
1.22 9.87e-03 GO:0051649 establishment of localization in cell
1.14 9.92e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.23 9.97e-03 GO:0006793 phosphorus metabolic process
1.23 9.97e-03 GO:0006796 phosphate metabolic process
1.13 1.17e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.20 1.46e-02 GO:0002376 immune system process
1.23 1.46e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.37 1.56e-02 GO:0032270 positive regulation of cellular protein metabolic process
1.32 1.68e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.13 1.70e-02 GO:0048731 system development
1.44 1.70e-02 GO:0010608 posttranscriptional regulation of gene expression
1.23 2.11e-02 GO:0009605 response to external stimulus
1.24 2.19e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.25 2.75e-02 GO:0046907 intracellular transport
1.45 2.78e-02 GO:0045321 leukocyte activation
1.13 3.00e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.11 3.02e-02 GO:0007275 multicellular organismal development
1.82 3.16e-02 GO:0007173 epidermal growth factor receptor signaling pathway
1.34 3.26e-02 GO:0007243 intracellular protein kinase cascade
1.34 3.26e-02 GO:0023014 signal transduction via phosphorylation event
1.10 3.30e-02 GO:0032502 developmental process
1.07 3.34e-02 GO:0050896 response to stimulus
1.16 4.11e-02 GO:0009059 macromolecule biosynthetic process
1.45 4.12e-02 GO:0030168 platelet activation
1.34 4.58e-02 GO:0051247 positive regulation of protein metabolic process
1.24 4.72e-02 GO:0048584 positive regulation of response to stimulus
1.11 4.96e-02 GO:0034641 cellular nitrogen compound metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.08 1.63e-15 GO:0044424 intracellular part
1.07 1.34e-13 GO:0005622 intracellular
1.14 4.25e-13 GO:0005634 nucleus
1.09 5.02e-11 GO:0043227 membrane-bounded organelle
1.08 6.33e-11 GO:0043226 organelle
1.09 1.12e-10 GO:0043231 intracellular membrane-bounded organelle
1.08 1.38e-10 GO:0043229 intracellular organelle
1.23 3.80e-10 GO:0044428 nuclear part
1.09 4.32e-10 GO:0005737 cytoplasm
1.24 2.48e-09 GO:0031981 nuclear lumen
1.22 1.45e-08 GO:0005829 cytosol
1.26 1.86e-07 GO:0005654 nucleoplasm
1.11 5.00e-07 GO:0044422 organelle part
1.11 8.12e-07 GO:0044446 intracellular organelle part
1.19 9.15e-07 GO:0043233 organelle lumen
1.19 1.68e-06 GO:0070013 intracellular organelle lumen
1.34 1.93e-06 GO:0044451 nucleoplasm part
1.18 1.98e-06 GO:0031974 membrane-enclosed lumen
1.10 3.95e-06 GO:0044444 cytoplasmic part
1.13 2.55e-05 GO:0032991 macromolecular complex
1.14 6.73e-05 GO:0043234 protein complex
1.03 1.61e-04 GO:0005623 cell
1.03 1.93e-04 GO:0044464 cell part
1.13 1.33e-03 GO:0043228 non-membrane-bounded organelle
1.13 1.33e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.29 4.61e-03 GO:0005694 chromosome
1.91 8.98e-03 GO:0016605 PML body
1.66 3.36e-02 GO:0016585 chromatin remodeling complex
1.28 4.07e-02 GO:0044427 chromosomal part
1.39 4.43e-02 GO:0000785 chromatin

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.19 8.99e-38 GO:0005515 protein binding
1.07 1.92e-13 GO:0005488 binding
1.32 7.80e-08 GO:0030528 transcription regulator activity
1.52 7.28e-06 GO:0016564 transcription repressor activity
1.32 5.09e-05 GO:0043565 sequence-specific DNA binding
1.25 1.87e-04 GO:0001071 nucleic acid binding transcription factor activity
1.25 1.87e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.28 5.44e-04 GO:0019899 enzyme binding
1.36 7.00e-03 GO:0003712 transcription cofactor activity
1.47 8.12e-03 GO:0004842 ubiquitin-protein ligase activity
1.35 8.38e-03 GO:0000988 protein binding transcription factor activity
1.35 8.38e-03 GO:0000989 transcription factor binding transcription factor activity
1.43 2.55e-02 GO:0019787 small conjugating protein ligase activity
1.45 3.63e-02 GO:0000975 regulatory region DNA binding
1.45 3.63e-02 GO:0001067 regulatory region nucleic acid binding
1.45 3.63e-02 GO:0044212 transcription regulatory region DNA binding
1.64 4.65e-02 GO:0051427 hormone receptor binding