Motif ID: SRF.p3

Z-value: 1.319


Transcription factors associated with SRF.p3:

Gene SymbolEntrez IDGene Name
SRF 6722 serum response factor (c-fos serum response element-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SRFchr6_+_432471680.552.6e-02Click!


Activity profile for motif SRF.p3.

activity profile for motif SRF.p3


Sorted Z-values histogram for motif SRF.p3

Sorted Z-values for motif SRF.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of SRF.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_34603290 4.166 NM_006097
NM_181526
MYL9

myosin, light chain 9, regulatory

chr20_+_34603311 4.018 MYL9
myosin, light chain 9, regulatory
chr5_+_137829065 2.577 EGR1
early growth response 1
chr15_-_32875040 1.781 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr22_+_29810981 1.541 SMTN
smoothelin
chr5_-_33928049 1.319 ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr1_+_221955876 1.307 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr5_-_33927724 1.247 NM_030955
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr7_-_5536783 1.138 ACTB
actin, beta
chr19_-_50518072 1.091 NM_001824
CKM
creatine kinase, muscle
chr19_-_50517971 0.974 CKM
creatine kinase, muscle
chr6_+_158322875 0.919 NM_003898
SYNJ2
synaptojanin 2
chr6_+_158322904 0.886 SYNJ2
synaptojanin 2
chr1_-_11830328 0.873 NM_006172
NPPA
natriuretic peptide A
chr14_-_52487558 0.869 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr20_-_33783409 0.867 RBM39
RNA binding motif protein 39
chr17_-_44026042 0.861 NM_002147
HOXB5
homeobox B5
chr11_+_116575249 0.856 NM_001001522
NM_003186
TAGLN

transgelin

chr3_+_189413414 0.845 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr19_-_40939756 0.831 NM_144617
HSPB6
heat shock protein, alpha-crystallin-related, B6
chr1_+_6226838 0.828 NM_001024598
HES3
hairy and enhancer of split 3 (Drosophila)
chr2_+_100545827 0.816 NM_024065
PDCL3
phosducin-like 3
chr6_+_43246897 0.807 NM_003131
SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr19_+_59064471 0.777 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr7_+_94123672 0.776 PEG10
paternally expressed 10
chr6_+_158322916 0.774 SYNJ2
synaptojanin 2
chr3_-_46879883 0.770 NM_000258
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr1_-_240228987 0.767 NM_001004343
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr7_-_27149750 0.764 NM_019102
HOXA5
homeobox A5
chr7_-_5536704 0.751 NM_001101
ACTB
actin, beta
chr6_+_43247168 0.735 SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr15_+_94670160 0.721 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr5_-_178983241 0.710 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr4_+_88147107 0.689 NM_005935
AFF1
AF4/FMR2 family, member 1
chr7_+_94123612 0.684 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr19_+_2427122 0.675 NM_015675
GADD45B
growth arrest and DNA-damage-inducible, beta
chr5_-_53642144 0.660 NM_019087
ARL15
ADP-ribosylation factor-like 15
chr6_+_151603201 0.644 AKAP12
A kinase (PRKA) anchor protein 12
chr1_-_227636462 0.641 NM_001100
ACTA1
actin, alpha 1, skeletal muscle
chr2_-_128149112 0.627 NM_001136037
NM_001161403
LIMS2

LIM and senescent cell antigen-like domains 2

chr5_-_53642060 0.624 ARL15
ADP-ribosylation factor-like 15
chr12_+_50731457 0.604 NM_002135
NM_173157
NR4A1

nuclear receptor subfamily 4, group A, member 1

chr4_+_81337663 0.603 NM_001099403
PRDM8
PR domain containing 8
chr21_-_46528594 0.600 MCM3AP
minichromosome maintenance complex component 3 associated protein
chr1_+_50347176 0.588 NM_001144774
NM_021952
ELAVL4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr2_-_231697999 0.585 NM_000867
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B
chr17_-_44026321 0.579 HOXB5
homeobox B5
chr9_+_36126667 0.561 GLIPR2
GLI pathogenesis-related 2
chr3_-_124821868 0.558 MYLK
myosin light chain kinase
chr19_+_12995782 0.542 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr3_-_153470022 0.537 LOC401093
hypothetical LOC401093
chr4_+_156899575 0.529 NM_000857
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr10_+_112247614 0.528 NM_004419
DUSP5
dual specificity phosphatase 5
chr1_-_166373434 0.527 GPR161
G protein-coupled receptor 161
chr12_+_74160779 0.525 NM_006851
GLIPR1
GLI pathogenesis-related 1
chr2_+_73973600 0.521 NM_001615
ACTG2
actin, gamma 2, smooth muscle, enteric
chr9_-_78710698 0.506 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr5_+_140730014 0.500 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr3_-_71376919 0.500 FOXP1
forkhead box P1
chr5_-_178983281 0.497 NM_005520
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr14_-_93512818 0.497 ASB2
ankyrin repeat and SOCS box containing 2
chr10_-_90702490 0.480 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr7_-_94123308 0.473 SGCE
sarcoglycan, epsilon
chr12_-_6642513 0.471 NM_001127582
NM_001127583
NM_001127584
NM_001127585
NM_001127586
NM_016162
ING4





inhibitor of growth family, member 4





chr2_+_73973640 0.469 ACTG2
actin, gamma 2, smooth muscle, enteric
chr6_+_151602787 0.467 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr22_+_36334400 0.466 NM_001001560
NM_001001561
NM_001172687
NM_013365
GGA1



golgi-associated, gamma adaptin ear containing, ARF binding protein 1



chr6_+_43247179 0.464 SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr12_-_23995220 0.457 SOX5
SRY (sex determining region Y)-box 5
chr10_+_75427853 0.454 NM_003373
NM_014000
VCL

vinculin

chr19_+_59064795 0.454 MYADM
myeloid-associated differentiation marker
chr7_-_94123362 0.438 SGCE
sarcoglycan, epsilon
chr4_+_14985272 0.436 NM_001135171
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr12_-_23995109 0.435 SOX5
SRY (sex determining region Y)-box 5
chr11_-_65424385 0.432 FOSL1
FOS-like antigen 1
chr12_-_48902692 0.432 NM_001113547
LIMA1
LIM domain and actin binding 1
chr7_-_107430566 0.429 NM_002291
LAMB1
laminin, beta 1
chr15_-_53369261 0.424 NM_183235
RAB27A
RAB27A, member RAS oncogene family
chr18_-_42804291 0.420 NM_001100817
TCEB3C
TCEB3CL
transcription elongation factor B polypeptide 3C (elongin A3)
transcription elongation factor B polypeptide 3C-like
chr12_+_60940404 0.418 NM_006313
USP15
ubiquitin specific peptidase 15
chr9_+_36126710 0.415 NM_022343
GLIPR2
GLI pathogenesis-related 2
chr5_-_58331515 0.413 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr14_+_73775927 0.413 NM_182894
VSX2
visual system homeobox 2
chr3_-_187124290 0.410 TRA2B
transformer 2 beta homolog (Drosophila)
chr1_-_206151055 0.409 NM_001025109
NM_001773
CD34

CD34 molecule

chr11_-_65424434 0.402 FOSL1
FOS-like antigen 1
chr7_-_94123413 0.397 NM_001099400
NM_001099401
NM_003919
SGCE


sarcoglycan, epsilon


chr7_+_113842470 0.395 FOXP2
forkhead box P2
chr6_-_105691675 0.391 BVES
blood vessel epicardial substance
chr6_+_167445284 0.382 NM_004367
CCR6
chemokine (C-C motif) receptor 6
chr6_-_109882116 0.379 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr15_-_68177280 0.376 TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr17_-_34603577 0.373 CACNB1
calcium channel, voltage-dependent, beta 1 subunit
chr7_+_115650240 0.366 NM_152829
TES
testis derived transcript (3 LIM domains)
chr1_+_50347188 0.365 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr15_+_43193810 0.365 NM_207581
DUOXA2
dual oxidase maturation factor 2
chr2_+_88148413 0.350 NM_198274
SMYD1
SET and MYND domain containing 1
chr18_-_42804531 0.349 NM_145653
TCEB3C
transcription elongation factor B polypeptide 3C (elongin A3)
chr3_-_124822113 0.346 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr10_-_64246080 0.341 EGR2
early growth response 2
chr1_-_166373351 0.339 GPR161
G protein-coupled receptor 161
chr17_-_4831388 0.334 NM_001171167
NM_001171168
CAMTA2

calmodulin binding transcription activator 2

chr11_+_59564323 0.327 NM_173801
PLAC1L
placenta-specific 1-like
chr5_-_39461054 0.326 NM_001343
DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr2_+_107969410 0.325 NM_021815
SLC5A7
solute carrier family 5 (choline transporter), member 7
chr4_+_24406182 0.318 NM_003102
SOD3
superoxide dismutase 3, extracellular
chr11_-_65424436 0.316 NM_005438
FOSL1
FOS-like antigen 1
chr11_-_75599433 0.312 WNT11
wingless-type MMTV integration site family, member 11
chr11_+_65945050 0.310 NM_178864
NPAS4
neuronal PAS domain protein 4
chr17_+_37122138 0.307 NM_000805
GAST
gastrin
chr5_+_137829077 0.306 NM_001964
EGR1
early growth response 1
chr7_-_526005 0.305 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr1_-_206151002 0.296 CD34
CD34 molecule
chr14_-_93512647 0.292 ASB2
ankyrin repeat and SOCS box containing 2
chr18_+_9698299 0.282 RAB31
RAB31, member RAS oncogene family
chr7_-_5535726 0.281 ACTB
actin, beta
chr8_-_22606653 0.266 NM_004430
EGR3
early growth response 3
chr2_-_215956429 0.263 FN1
fibronectin 1
chr6_-_25834733 0.261 NM_170745
HIST1H2AA
histone cluster 1, H2aa
chr3_+_150675117 0.258 NM_004617
TM4SF4
transmembrane 4 L six family member 4
chr10_-_64246129 0.254 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr5_+_169749068 0.251


chr2_+_87536106 0.248 NCRNA00152
non-protein coding RNA 152
chr15_-_68177244 0.241 TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr1_-_166373159 0.240 GPR161
G protein-coupled receptor 161
chr13_+_26723689 0.234 NM_000982
RPL21
ribosomal protein L21
chr7_-_121731721 0.233 NM_001024613
NM_001160264
FEZF1

FEZ family zinc finger 1

chr18_-_42810446 0.233 NM_145653
TCEB3C
transcription elongation factor B polypeptide 3C (elongin A3)
chr11_-_8982107 0.233 NM_020645
NRIP3
nuclear receptor interacting protein 3
chr4_+_88187215 0.229 AFF1
AF4/FMR2 family, member 1
chr14_+_62740878 0.222 NM_020663
RHOJ
ras homolog gene family, member J
chr5_-_56283672 0.220 NM_152622
MIER3
mesoderm induction early response 1, family member 3
chr20_-_42249146 0.220 JPH2
junctophilin 2
chr2_-_105421661 0.217 NM_201557
FHL2
four and a half LIM domains 2
chr17_-_77386156 0.213 DYSFIP1
dysferlin interacting protein 1
chr7_+_134114701 0.209 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr9_-_97309507 0.209 NM_001083606
PTCH1
patched 1
chr6_+_101948102 0.205


chr7_-_44147436 0.204 NM_021223
MYL7
myosin, light chain 7, regulatory
chr6_-_29635680 0.197 NM_006398
UBD
ubiquitin D
chr14_-_73296643 0.194 NM_194278
C14orf43
chromosome 14 open reading frame 43
chr7_+_94123556 0.194 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chr14_+_74815233 0.192 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr5_+_131424245 0.191 NM_000588
IL3
interleukin 3 (colony-stimulating factor, multiple)
chr5_+_60663842 0.191 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr16_+_30015899 0.190


chr3_+_145173329 0.187 NM_173552
C3orf58
chromosome 3 open reading frame 58
chr7_+_142788521 0.187 ZYX
zyxin
chr22_+_28206180 0.185 NM_021076
NEFH
neurofilament, heavy polypeptide
chr16_+_29984611 0.183 ALDOA
aldolase A, fructose-bisphosphate
chr17_+_38256710 0.182 NM_003734
AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr19_-_54618410 0.182 NM_178449
PTH2
parathyroid hormone 2
chr5_-_150264696 0.178 NM_001172831
NM_001172832
NM_052860
ZNF300


zinc finger protein 300


chr20_+_32610161 0.172 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr19_+_50109416 0.172 APOC1
apolipoprotein C-I
chr15_-_63147350 0.169 NM_016563
RASL12
RAS-like, family 12
chr1_+_179324458 0.166 IER5
immediate early response 5
chr15_+_72006015 0.166 LOXL1
lysyl oxidase-like 1
chr7_+_107318821 0.163 NM_000108
DLD
dihydrolipoamide dehydrogenase
chr7_+_143378393 0.162 NM_012365
OR2A5
olfactory receptor, family 2, subfamily A, member 5
chr16_+_29984591 0.162 ALDOA
aldolase A, fructose-bisphosphate
chr1_-_35097232 0.161 NM_001164824
C1orf212
chromosome 1 open reading frame 212
chr17_+_30498948 0.161 NM_001033576
NM_173167
UNC45B

unc-45 homolog B (C. elegans)

chr7_-_80386258 0.161 SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr20_-_33706532 0.160 RBM12
RNA binding motif protein 12
chr19_-_15204767 0.159 NM_001142886
EPHX3
epoxide hydrolase 3
chr10_+_80777234 0.156 PPIF
peptidylprolyl isomerase F
chr11_+_66070949 0.155 NM_001104
ACTN3
actinin, alpha 3
chr7_-_75280962 0.154 NM_002991
CCL24
chemokine (C-C motif) ligand 24
chr11_-_30562324 0.152 MPPED2
metallophosphoesterase domain containing 2
chr19_+_62593000 0.150 NM_001172773
NM_152909
ZNF548

zinc finger protein 548

chr5_+_92944680 0.150 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr16_+_29984647 0.144 ALDOA
aldolase A, fructose-bisphosphate
chr19_+_62593142 0.142 ZNF548
ZNF17
zinc finger protein 548
zinc finger protein 17
chr16_+_29984621 0.141 ALDOA
aldolase A, fructose-bisphosphate
chr7_-_5535432 0.141 ACTB
actin, beta
chr17_-_77386212 0.138 NM_001007533
DYSFIP1
dysferlin interacting protein 1
chr16_+_31390567 0.137 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr12_-_90029672 0.136 NM_002345
LUM
lumican
chr10_+_80777265 0.136 PPIF
peptidylprolyl isomerase F
chr1_-_71319559 0.134 NM_005455
NM_203350
ZRANB2

zinc finger, RAN-binding domain containing 2

chr19_-_50975603 0.132 NM_001081563
DMPK
dystrophia myotonica-protein kinase
chr14_-_73296387 0.129 C14orf43
chromosome 14 open reading frame 43
chr9_-_97309301 0.129 NM_001083607
PTCH1
patched 1
chr7_+_142788579 0.126 ZYX
zyxin
chr16_+_29984544 0.125 NM_184041
ALDOA
aldolase A, fructose-bisphosphate
chr3_+_25445071 0.123 RARB
retinoic acid receptor, beta
chr3_+_150675169 0.123 TM4SF4
transmembrane 4 L six family member 4
chr1_+_113064711 0.121 NM_001004440
NM_182759
FAM19A3

family with sequence similarity 19 (chemokine (C-C motif)-like), member A3

chr20_+_4650499 0.120 NM_012409
PRND
prion protein 2 (dublet)
chr7_+_12692938 0.120 NM_001037164
NM_212460
ARL4A

ADP-ribosylation factor-like 4A

chr11_+_43920385 0.120 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr1_+_242883057 0.119 PPPDE1
PPPDE peptidase domain containing 1
chr2_-_69033515 0.119 NM_182536
GKN2
gastrokine 2
chr2_-_31659472 0.119 NM_000348
SRD5A2
steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
chr7_+_142788517 0.118 ZYX
zyxin
chr11_-_64402629 0.118 NM_006795
EHD1
EH-domain containing 1
chr3_-_158704056 0.117 NM_001167915
NM_001167916
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr4_+_186301410 0.117 NM_001151
SLC25A4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr6_+_12824873 0.115 PHACTR1
phosphatase and actin regulator 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
8.41 1.97e-11 GO:0003012 muscle system process
8.74 3.65e-11 GO:0006936 muscle contraction
6.08 3.49e-06 GO:0007517 muscle organ development
1.60 7.16e-06 GO:0032501 multicellular organismal process
1.76 8.00e-06 GO:0032502 developmental process
1.85 1.00e-05 GO:0048856 anatomical structure development
4.83 1.87e-05 GO:0061061 muscle structure development
1.79 2.18e-05 GO:0007275 multicellular organismal development
3.13 6.22e-05 GO:0010628 positive regulation of gene expression
1.86 6.82e-05 GO:0048731 system development
11.60 7.25e-05 GO:0030048 actin filament-based movement
4.37 2.03e-04 GO:0030029 actin filament-based process
2.88 2.16e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.80 4.12e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
2.84 4.91e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
12.44 1.33e-03 GO:0030049 muscle filament sliding
12.44 1.33e-03 GO:0033275 actin-myosin filament sliding
12.11 1.61e-03 GO:0070252 actin-mediated cell contraction
2.61 1.75e-03 GO:0031328 positive regulation of cellular biosynthetic process
2.92 1.88e-03 GO:0045893 positive regulation of transcription, DNA-dependent
6.92 1.99e-03 GO:0003007 heart morphogenesis
2.56 2.48e-03 GO:0009891 positive regulation of biosynthetic process
2.28 3.56e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.94 3.69e-03 GO:0048513 organ development
2.20 3.95e-03 GO:0009893 positive regulation of metabolic process
2.72 6.51e-03 GO:0051254 positive regulation of RNA metabolic process
2.21 6.88e-03 GO:0031325 positive regulation of cellular metabolic process
2.32 1.31e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
5.10 3.08e-02 GO:0060537 muscle tissue development
1.80 3.15e-02 GO:0030154 cell differentiation
2.90 3.83e-02 GO:0072358 cardiovascular system development
2.90 3.83e-02 GO:0072359 circulatory system development
2.89 3.95e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
3.84 4.23e-02 GO:0007507 heart development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
5.75 3.85e-10 GO:0015629 actin cytoskeleton
8.55 1.18e-08 GO:0043292 contractile fiber
8.73 3.57e-08 GO:0044449 contractile fiber part
8.50 5.21e-08 GO:0030016 myofibril
15.94 5.34e-06 GO:0042641 actomyosin
8.05 6.28e-06 GO:0030017 sarcomere
7.97 7.05e-06 GO:0005925 focal adhesion
10.27 8.51e-06 GO:0016459 myosin complex
7.59 1.23e-05 GO:0005924 cell-substrate adherens junction
7.31 1.89e-05 GO:0030055 cell-substrate junction
16.44 3.26e-05 GO:0001725 stress fiber
2.18 4.30e-05 GO:0005856 cytoskeleton
15.34 5.45e-05 GO:0032432 actin filament bundle
5.74 9.53e-05 GO:0005912 adherens junction
25.29 1.90e-04 GO:0031672 A band
5.18 3.05e-04 GO:0070161 anchoring junction
18.26 1.19e-03 GO:0005859 muscle myosin complex
16.44 2.10e-03 GO:0016460 myosin II complex
11.60 2.29e-03 GO:0005884 actin filament
2.16 5.30e-03 GO:0044430 cytoskeletal part
3.74 1.05e-02 GO:0016323 basolateral plasma membrane
8.22 1.75e-02 GO:0031674 I band
1.21 2.87e-02 GO:0043229 intracellular organelle
1.21 3.23e-02 GO:0043226 organelle
1.57 3.51e-02 GO:0043228 non-membrane-bounded organelle
1.57 3.51e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.17 3.68e-02 GO:0044424 intracellular part

Gene overrepresentation in function category:

enrichment   p-value GO term description
12.23 4.82e-05 GO:0008307 structural constituent of muscle
15.78 3.33e-04 GO:0017022 myosin binding
3.75 3.55e-04 GO:0003779 actin binding
2.28 1.73e-03 GO:0030528 transcription regulator activity
6.58 1.87e-03 GO:0003704 specific RNA polymerase II transcription factor activity
2.80 2.95e-03 GO:0008092 cytoskeletal protein binding
1.18 3.03e-03 GO:0005488 binding
2.55 5.48e-03 GO:0046983 protein dimerization activity
2.18 7.67e-03 GO:0001071 nucleic acid binding transcription factor activity
2.18 7.67e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.63 3.78e-02 GO:0003677 DNA binding
2.38 4.56e-02 GO:0005198 structural molecule activity