Motif ID: TBP.p2

Z-value: 1.471


Transcription factors associated with TBP.p2:

Gene SymbolEntrez IDGene Name
TBP 6908 TATA box binding protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TBPchr6_+_170705345-0.126.5e-01Click!


Activity profile for motif TBP.p2.

activity profile for motif TBP.p2


Sorted Z-values histogram for motif TBP.p2

Sorted Z-values for motif TBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBP.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_51585004 2.165 NM_002273
KRT8
keratin 8
chr1_+_151596953 1.522 NM_002965
S100A9
S100 calcium binding protein A9
chr4_+_74953971 1.497 NM_001511
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr1_-_151296611 1.135 NM_005988
SPRR2A
small proline-rich protein 2A
chr19_-_12773591 1.066 NM_005809
NM_181738
PRDX2

peroxiredoxin 2

chr17_-_37034288 1.045 NM_000422
KRT17
keratin 17
chr7_-_526005 0.952 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr1_-_41100589 0.911 NM_133467
CITED4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr1_+_151270301 0.906 NM_003125
SPRR1B
small proline-rich protein 1B
chr21_+_44729875 0.894


chr12_-_123965099 0.888 UBC
ubiquitin C
chr17_+_24598000 0.881 NM_005208
CRYBA1
crystallin, beta A1
chr11_-_2907169 0.875 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr4_-_75183700 0.868 CXCL2
chemokine (C-X-C motif) ligand 2
chr11_-_6418705 0.862 NM_000613
HPX
hemopexin
chr15_-_61461127 0.854 NM_001218
NM_206925
CA12

carbonic anhydrase XII

chrX_-_103386215 0.842 NM_153448
ESX1
ESX homeobox 1
chr1_+_12774132 0.781 NM_023013
PRAMEF1
PRAME family member 1
chr1_-_154941861 0.776 NM_001878
CRABP2
cellular retinoic acid binding protein 2
chr21_-_44795769 0.772 NM_198693
KRTAP10-2
keratin associated protein 10-2
chr1_+_17507276 0.770 NM_012387
PADI4
peptidyl arginine deiminase, type IV
chr17_-_71287417 0.758 NM_005324
H3F3B
H3 histone, family 3B (H3.3B)
chr17_-_36294962 0.755 NM_019010
KRT20
keratin 20
chr1_-_199732323 0.726 NM_001193572
CSRP1
cysteine and glycine-rich protein 1
chr16_+_142853 0.710 NM_005332
HBZ
hemoglobin, zeta
chr19_+_53650577 0.702 NM_013348
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr7_+_142723340 0.699 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr6_-_26232109 0.698 NM_003526
HIST1H2BG
HIST1H2BC
histone cluster 1, H2bg
histone cluster 1, H2bc
chr16_+_25135783 0.697 NM_001169
AQP8
aquaporin 8
chr15_-_61460967 0.681 CA12
carbonic anhydrase XII
chr5_+_149526533 0.680 NM_001804
CDX1
caudal type homeobox 1
chr6_-_27222556 0.664 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr22_+_30670435 0.649 NM_003405
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chr12_-_51298599 0.641 NM_175068
KRT73
keratin 73
chr12_+_50913274 0.635 KRT7
keratin 7
chr19_+_12910428 0.623 CALR
calreticulin
chr17_-_39375327 0.621 NM_002722
PPY
pancreatic polypeptide
chr3_-_10307408 0.610 NM_001134941
NM_016362
GHRL

ghrelin/obestatin prepropeptide

chr19_+_12910440 0.609 CALR
calreticulin
chr17_-_59304729 0.597 NM_020991
NM_022644
NM_022645
CSH2


chorionic somatomammotropin hormone 2


chr10_-_135290288 0.595 NM_001080998
FRG2B
FRG2
FSHD region gene 2 family, member B
FSHD region gene 2
chr6_+_27222839 0.591 NM_080596
HIST1H2AH
histone cluster 1, H2ah
chr1_-_58815415 0.588 TACSTD2
tumor-associated calcium signal transducer 2
chr13_-_113155839 0.585 NM_138430
ADPRHL1
ADP-ribosylhydrolase like 1
chr17_-_36276987 0.582 NM_000223
KRT12
keratin 12
chr1_-_151310707 0.581 NM_001017418
SPRR2B
small proline-rich protein 2B
chr6_-_26358811 0.580 NM_021018
HIST1H3F
histone cluster 1, H3f
chr17_-_36834183 0.578 NM_003770
KRT37
keratin 37
chr14_-_22947320 0.574 NM_002471
MYH6
myosin, heavy chain 6, cardiac muscle, alpha
chr16_-_55259405 0.567 NM_005950
MT1G
metallothionein 1G
chr15_-_58477407 0.553 NM_001002857
NM_001002858
NM_001136015
NM_004039
ANXA2



annexin A2



chr16_+_55243311 0.551 NM_005947
MT1B
metallothionein 1B
chr6_-_26125939 0.549 NM_005325
HIST1H1A
histone cluster 1, H1a
chr10_+_47867667 0.542 NM_001137556
NM_001137549
NM_001137548
FAM25B
FAM25G
FAM25C
family with sequence similarity 25, member B
family with sequence similarity 25, member G
family with sequence similarity 25, member C
chr1_-_226202210 0.540 NM_003395
WNT9A
wingless-type MMTV integration site family, member 9A
chr1_+_148089251 0.537 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr2_-_121759237 0.536 NM_014553
TFCP2L1
transcription factor CP2-like 1
chr3_+_187984029 0.535 NM_001967
EIF4A2
eukaryotic translation initiation factor 4A2
chr3_-_24511456 0.530 THRB
thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
chr19_+_12910391 0.527 NM_004343
CALR
calreticulin
chr6_-_26140266 0.522 NM_003537
HIST1H3B
histone cluster 1, H3b
chr1_-_172103745 0.519 GAS5
growth arrest-specific 5 (non-protein coding)
chr12_-_51457371 0.517 NM_015848
KRT76
keratin 76
chr17_-_36928604 0.514 NM_002275
KRT15
keratin 15
chr3_-_172070641 0.512 NM_001099645
RPL22L1
ribosomal protein L22-like 1
chr10_-_46601687 0.510 NM_001137556
NM_001137549
NM_001137548
FAM25B
FAM25G
FAM25C
family with sequence similarity 25, member B
family with sequence similarity 25, member G
family with sequence similarity 25, member C
chr1_-_45760115 0.506 NM_002574
NM_181696
NM_181697
PRDX1


peroxiredoxin 1


chr11_+_61794205 0.501 NM_002411
SCGB2A2
secretoglobin, family 2A, member 2
chr19_-_54618410 0.500 NM_178449
PTH2
parathyroid hormone 2
chr12_-_123965539 0.494 NM_021009
UBC
ubiquitin C
chr17_-_59327602 0.494 NM_001317
NM_022640
NM_022641
CSH1


CSH2
chorionic somatomammotropin hormone 1 (placental lactogen)


chorionic somatomammotropin hormone 2
chr1_+_148090804 0.494 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr21_+_44818033 0.487 NM_198687
KRTAP10-4
keratin associated protein 10-4
chr21_+_33320080 0.482 NM_005806
OLIG2
oligodendrocyte lineage transcription factor 2
chr7_+_100399623 0.481 NM_001164462
MUC12
mucin 12, cell surface associated
chr11_-_122438016 0.478 NM_006597
NM_153201
HSPA8

heat shock 70kDa protein 8

chr6_+_3009120 0.469 RIPK1
receptor (TNFRSF)-interacting serine-threonine kinase 1
chr1_-_148050534 0.465 NM_001024599
NM_001161334
HIST2H2BF

histone cluster 2, H2bf

chr5_-_141318810 0.463 NM_016580
PCDH12
protocadherin 12
chr22_+_29810981 0.460 SMTN
smoothelin
chr17_-_37144408 0.457 NM_001079870
NM_001079871
NM_177977
HAP1


huntingtin-associated protein 1


chrX_-_115508164 0.457 NM_001017978
CXorf61
chromosome X open reading frame 61
chr9_+_130354490 0.457 NM_001130438
NM_001195532
NM_003127
SPTAN1


spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)


chr7_+_100399409 0.455


chr11_-_122438054 0.454 HSPA8
heat shock 70kDa protein 8
chr11_-_2863536 0.453 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr17_-_59312892 0.447 NM_002059
NM_022556
NM_022557
NM_022558
GH2



growth hormone 2



chr1_-_150599105 0.446 NM_001014342
FLG2
filaggrin family member 2
chr12_-_51360439 0.446 NM_006121
KRT1
keratin 1
chrX_-_52843112 0.441 NM_001009616
SPANXN5
SPANX family, member N5
chr11_+_2355099 0.440 CD81
CD81 molecule
chr12_-_51153788 0.433 NM_173086
KRT6C
keratin 6C
chr19_+_40465249 0.429 NM_021175
HAMP
hepcidin antimicrobial peptide
chr2_-_240728745 0.424 NM_148961
OTOS
otospiralin
chr9_+_129951552 0.423 NM_005564
LCN2
lipocalin 2
chr14_+_74815233 0.422 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr4_-_75123193 0.422 NM_002090
CXCL3
chemokine (C-X-C motif) ligand 3
chrX_-_30237403 0.422 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr11_+_62189354 0.422 NM_001043229
METTL12
methyltransferase like 12
chr19_-_2002222 0.421 NM_017572
NM_199054
MKNK2

MAP kinase interacting serine/threonine kinase 2

chr5_+_132037271 0.418 NM_000589
NM_172348
IL4

interleukin 4

chr12_+_8866416 0.417 NM_144670
A2ML1
alpha-2-macroglobulin-like 1
chr4_-_175680157 0.416 HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr17_+_29606408 0.415 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr17_-_77386212 0.414 NM_001007533
DYSFIP1
dysferlin interacting protein 1
chr19_+_18357966 0.413 NM_004864
GDF15
growth differentiation factor 15
chr1_+_85819004 0.412 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr17_+_29621352 0.412 NM_006273
CCL7
chemokine (C-C motif) ligand 7
chr1_+_184532027 0.411 NM_001127708
NM_001127709
NM_001127710
NM_005807
PRG4



proteoglycan 4



chr1_-_151630168 0.409 NM_002964
S100A8
S100 calcium binding protein A8
chr1_-_148079357 0.409 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr11_-_102250876 0.409 NM_002426
MMP12
matrix metallopeptidase 12 (macrophage elastase)
chr17_+_53625084 0.402 NM_000502
EPX
eosinophil peroxidase
chrX_+_153339814 0.402 NM_017514
PLXNA3
plexin A3
chr1_+_42391678 0.402 NM_007102
GUCA2B
guanylate cyclase activator 2B (uroguanylin)
chr11_+_30209138 0.400 NM_000510
NM_001018080
FSHB

follicle stimulating hormone, beta polypeptide

chr19_+_54160468 0.398 FTL
ferritin, light polypeptide
chr12_-_51173238 0.398 NM_005554
KRT6A
keratin 6A
chr4_+_74825138 0.390 NM_000584
IL8
interleukin 8
chr3_+_62279707 0.378 C3orf14
chromosome 3 open reading frame 14
chr1_+_12839527 0.372 NM_023014
PRAMEF2
PRAME family member 2
chr6_+_26232351 0.370 NM_003512
HIST1H2AC
histone cluster 1, H2ac
chr12_-_87498225 0.369 NM_000899
NM_003994
KITLG

KIT ligand

chr1_-_148051859 0.367 NM_001123375
HIST2H3D
histone cluster 2, H3d
chr7_+_115650240 0.365 NM_152829
TES
testis derived transcript (3 LIM domains)
chr16_-_4794749 0.365 GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr11_+_64946848 0.365


chr17_-_36113502 0.364 NM_019016
KRT24
keratin 24
chr7_+_75769927 0.362 HSPB1
heat shock 27kDa protein 1
chr11_-_18226743 0.352 NM_001127380
NM_030754
SAA2

serum amyloid A2

chr6_-_27907283 0.352 NM_003541
HIST1H4A
HIST1H4F
HIST1H4K
HIST1H4J
histone cluster 1, H4a
histone cluster 1, H4f
histone cluster 1, H4k
histone cluster 1, H4j
chr11_+_2355119 0.347 NM_004356
CD81
CD81 molecule
chr11_+_64946820 0.347 NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr16_+_2747491 0.346


chr19_+_523575 0.346 BSG
basigin (Ok blood group)
chr1_+_157824239 0.344 NM_001639
APCS
amyloid P component, serum
chr10_-_62373828 0.344 NM_014836
RHOBTB1
Rho-related BTB domain containing 1
chr12_+_12935759 0.343 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr20_+_43269051 0.342 NM_003007
SEMG1
semenogelin I
chr22_-_38045555 0.339 NM_000967
NM_001033853
RPL3

ribosomal protein L3

chr17_+_36493927 0.338 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr12_-_51001407 0.337 NM_002282
KRT83
keratin 83
chr11_+_1064869 0.335 NM_002457
MUC2
mucin 2, oligomeric mucus/gel-forming
chr11_-_1026654 0.334 NM_005961
MUC6
mucin 6, oligomeric mucus/gel-forming
chr1_-_26266571 0.330 NM_032588
TRIM63
tripartite motif containing 63
chr19_+_54160369 0.330 NM_000146
FTL
ferritin, light polypeptide
chr3_+_195336625 0.327 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr6_-_74287453 0.325 NM_001402
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr17_-_77386156 0.320 DYSFIP1
dysferlin interacting protein 1
chr11_-_102001259 0.318 NM_004771
MMP20
matrix metallopeptidase 20
chr1_+_40715888 0.317 NM_198494
ZNF642
zinc finger protein 642
chr15_+_43510054 0.314 NM_032413
NM_197955
C15orf48

chromosome 15 open reading frame 48

chr19_+_12763285 0.313 JUNB
jun B proto-oncogene
chr7_+_73826244 0.308 NM_000265
NCF1
NCF1B
NCF1C
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
neutrophil cytosolic factor 1C pseudogene
chr21_+_43462209 0.308 NM_000394
CRYAA
crystallin, alpha A
chr11_-_5204769 0.307 NM_000518
HBB
hemoglobin, beta
chr4_+_101090648 0.307 LOC256880
hypothetical LOC256880
chr5_+_145698779 0.305 NM_002700
POU4F3
POU class 4 homeobox 3
chr4_-_75183860 0.304 NM_002089
CXCL2
chemokine (C-X-C motif) ligand 2
chr8_+_22075112 0.303 NM_001172357
NM_001172410
NM_003018
SFTPC


surfactant protein C


chr10_-_3817418 0.301 NM_001160124
NM_001160125
NM_001300
KLF6


Kruppel-like factor 6


chr4_+_75393053 0.299 NM_001013442
EPGN
epithelial mitogen homolog (mouse)
chr12_-_52187638 0.298 NM_003717
NPFF
neuropeptide FF-amide peptide precursor
chr3_+_110338250 0.298 FLJ22763
hypothetical LOC401081
chr10_+_81360646 0.296 NM_001093770
NM_001164644
NM_001164645
NM_001164646
NM_001164647
NM_005411
SFTPA1





surfactant protein A1





chrX_+_16578201 0.296 NM_004057
S100G
S100 calcium binding protein G
chr1_-_202402043 0.295 NM_000537
REN
renin
chr5_-_140033310 0.292 NM_194249
DND1
dead end homolog 1 (zebrafish)
chr6_-_50025115 0.292 NM_001166478
DEFB133
defensin, beta 133
chr9_+_139255563 0.290 TUBB2C
tubulin, beta 2C
chr12_-_51476047 0.289 NM_057088
KRT3
keratin 3
chrX_+_118486419 0.287 SLC25A5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr9_-_135074364 0.283 NM_014581
OBP2B
OBP2A
odorant binding protein 2B
odorant binding protein 2A
chr18_+_55038369 0.283 NM_001012512
NM_001012513
NM_002091
GRP


gastrin-releasing peptide


chr2_+_107969410 0.282 NM_021815
SLC5A7
solute carrier family 5 (choline transporter), member 7
chr15_+_39008822 0.282 NM_019074
DLL4
delta-like 4 (Drosophila)
chr11_+_18244383 0.280 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr10_-_44794146 0.279 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr6_+_33280396 0.278 NM_014234
HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
chr19_+_54160399 0.276 FTL
ferritin, light polypeptide
chr19_-_51856129 0.276 NM_145056
DACT3
dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr6_-_74287483 0.275 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr6_+_31791063 0.275 NM_021246
LY6G6D
lymphocyte antigen 6 complex, locus G6D
chr6_-_2848460 0.275 NM_004155
SERPINB9
serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr9_+_33785558 0.270 NM_002771
PRSS3
protease, serine, 3
chr17_-_10362583 0.268 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr1_-_150805852 0.268 NM_178435
LCE3E
late cornified envelope 3E
chr15_-_32875040 0.267 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr8_+_23016271 0.264 NM_003841
TNFRSF10C
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
chr20_+_36365965 0.263 NM_001725
BPI
bactericidal/permeability-increasing protein
chr8_+_70567634 0.263 SULF1
sulfatase 1
chr9_+_138677197 0.259 NM_201446
NM_016215
EGFL7

EGF-like-domain, multiple 7

chr11_-_76059435 0.259 NM_001128922
LRRC32
leucine rich repeat containing 32
chr5_+_179180695 0.259 SQSTM1
sequestosome 1
chr1_-_117554999 0.258 NM_024626
VTCN1
V-set domain containing T cell activation inhibitor 1
chr11_-_102219450 0.255 NM_002422
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr16_-_87378872 0.254 NM_001142864
FAM38A
family with sequence similarity 38, member A
chr15_+_72828235 0.253 NM_000761
CYP1A2
cytochrome P450, family 1, subfamily A, polypeptide 2
chr12_-_51047521 0.253 NM_002283
KRT85
keratin 85
chr19_-_11452439 0.253 NM_001420
NM_032281
ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
7.44 4.90e-13 GO:0034728 nucleosome organization
1.51 2.27e-12 GO:0032501 multicellular organismal process
7.60 4.05e-12 GO:0006334 nucleosome assembly
7.22 1.46e-11 GO:0031497 chromatin assembly
1.64 1.59e-11 GO:0032502 developmental process
6.52 5.07e-11 GO:0071824 protein-DNA complex subunit organization
6.61 1.21e-10 GO:0065004 protein-DNA complex assembly
1.97 2.86e-10 GO:0048513 organ development
1.72 7.02e-10 GO:0048731 system development
1.67 7.33e-10 GO:0048856 anatomical structure development
1.63 1.04e-09 GO:0007275 multicellular organismal development
3.12 1.64e-09 GO:0034621 cellular macromolecular complex subunit organization
5.38 5.10e-09 GO:0006333 chromatin assembly or disassembly
5.52 7.62e-09 GO:0006323 DNA packaging
2.46 2.82e-08 GO:0006952 defense response
4.94 3.51e-08 GO:0071103 DNA conformation change
4.34 5.41e-08 GO:0008544 epidermis development
3.28 9.67e-08 GO:0034622 cellular macromolecular complex assembly
1.70 1.93e-07 GO:0006950 response to stress
2.29 3.62e-07 GO:0051704 multi-organism process
2.32 5.98e-07 GO:0043933 macromolecular complex subunit organization
9.12 9.24e-07 GO:0031424 keratinization
11.57 1.08e-06 GO:0070301 cellular response to hydrogen peroxide
3.41 4.31e-06 GO:0010035 response to inorganic substance
3.31 8.86e-06 GO:0006954 inflammatory response
6.87 1.20e-05 GO:0034599 cellular response to oxidative stress
8.42 1.21e-05 GO:0034614 cellular response to reactive oxygen species
2.16 2.35e-05 GO:0009888 tissue development
2.31 2.40e-05 GO:0065003 macromolecular complex assembly
1.63 2.54e-05 GO:0042221 response to chemical stimulus
6.35 3.64e-05 GO:0042542 response to hydrogen peroxide
2.22 4.24e-05 GO:0006955 immune response
2.06 1.29e-04 GO:0009611 response to wounding
3.21 1.82e-04 GO:0009617 response to bacterium
11.78 2.16e-04 GO:0045103 intermediate filament-based process
5.98 2.44e-04 GO:0030216 keratinocyte differentiation
4.97 3.62e-04 GO:0000302 response to reactive oxygen species
3.42 1.07e-03 GO:0006979 response to oxidative stress
12.13 1.09e-03 GO:0045104 intermediate filament cytoskeleton organization
9.82 1.12e-03 GO:0042743 hydrogen peroxide metabolic process
2.08 1.14e-03 GO:0071844 cellular component assembly at cellular level
5.18 1.44e-03 GO:0009913 epidermal cell differentiation
11.46 1.73e-03 GO:0042744 hydrogen peroxide catabolic process
1.85 2.14e-03 GO:0022607 cellular component assembly
6.00 2.20e-03 GO:0051591 response to cAMP
1.56 2.82e-03 GO:0030154 cell differentiation
4.06 5.25e-03 GO:0007565 female pregnancy
2.40 6.59e-03 GO:0051707 response to other organism
1.73 6.60e-03 GO:0002376 immune system process
16.37 7.89e-03 GO:0045109 intermediate filament organization
6.63 8.67e-03 GO:0072593 reactive oxygen species metabolic process
2.22 9.14e-03 GO:0009607 response to biotic stimulus
1.52 9.44e-03 GO:0048869 cellular developmental process
1.85 9.83e-03 GO:0070887 cellular response to chemical stimulus
2.20 1.10e-02 GO:0006935 chemotaxis
2.20 1.10e-02 GO:0042330 taxis
1.23 1.31e-02 GO:0050896 response to stimulus
14.73 1.53e-02 GO:0046689 response to mercury ion
14.73 1.53e-02 GO:0048246 macrophage chemotaxis
5.46 1.66e-02 GO:0002526 acute inflammatory response
1.71 1.91e-02 GO:0044085 cellular component biogenesis
1.78 2.28e-02 GO:0009605 response to external stimulus
4.31 2.72e-02 GO:0045637 regulation of myeloid cell differentiation
3.03 3.65e-02 GO:0030855 epithelial cell differentiation
1.82 4.39e-02 GO:0040011 locomotion

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
10.23 2.51e-41 GO:0005882 intermediate filament
8.85 2.83e-37 GO:0045111 intermediate filament cytoskeleton
13.62 2.58e-31 GO:0045095 keratin filament
2.34 8.26e-24 GO:0005576 extracellular region
3.44 2.01e-23 GO:0005615 extracellular space
3.05 4.82e-23 GO:0044421 extracellular region part
10.93 2.29e-16 GO:0000786 nucleosome
2.46 5.16e-13 GO:0044430 cytoskeletal part
6.99 1.47e-11 GO:0032993 protein-DNA complex
2.01 4.15e-10 GO:0005856 cytoskeleton
1.67 2.18e-09 GO:0043228 non-membrane-bounded organelle
1.67 2.18e-09 GO:0043232 intracellular non-membrane-bounded organelle
1.45 5.10e-06 GO:0032991 macromolecular complex
3.29 1.42e-05 GO:0000785 chromatin
12.27 5.93e-03 GO:0005833 hemoglobin complex
8.42 1.06e-02 GO:0001533 cornified envelope
2.12 4.10e-02 GO:0031012 extracellular matrix
2.20 4.14e-02 GO:0005625 soluble fraction

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.46 1.62e-17 GO:0005198 structural molecule activity
6.84 3.55e-11 GO:0005179 hormone activity
2.39 3.83e-11 GO:0005102 receptor binding
4.59 2.01e-10 GO:0005125 cytokine activity
9.61 3.53e-09 GO:0008009 chemokine activity
8.66 1.89e-08 GO:0042379 chemokine receptor binding
4.30 3.01e-08 GO:0005126 cytokine receptor binding
3.60 8.86e-05 GO:0001664 G-protein-coupled receptor binding
5.39 1.72e-04 GO:0005200 structural constituent of cytoskeleton
13.60 6.31e-04 GO:0005344 oxygen transporter activity
3.34 1.89e-03 GO:0008083 growth factor activity
2.98 2.00e-03 GO:0005506 iron ion binding
3.59 4.65e-03 GO:0020037 heme binding
3.37 9.93e-03 GO:0046906 tetrapyrrole binding
2.16 3.43e-02 GO:0030246 carbohydrate binding
6.07 3.62e-02 GO:0004601 peroxidase activity
6.07 3.62e-02 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor