Motif ID: TEAD1.p2

Z-value: 2.656


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
TEAD1 7003 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 8463 TEA domain family member 2
TEAD3 7005 TEAD3 TEA domain family member 3
TEAD4 7004 TEAD4 TEA domain family member 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TEAD4chr12_+_29387030.572.2e-02Click!
TEAD1chr11_+_129173690.495.6e-02Click!
TEAD2chr19_-_545574500.332.1e-01Click!
TEAD3chr6_-_35572694-0.116.8e-01Click!


Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_39460687 8.973 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr6_-_132314004 8.741 NM_001901
CTGF
connective tissue growth factor
chr1_-_212791467 8.247 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr1_-_212791597 7.958 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr10_+_123862430 6.344 TACC2
transforming, acidic coiled-coil containing protein 2
chr5_-_39460787 6.054 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr4_+_184257337 5.510 NM_024949
WWC2
WW and C2 domain containing 2
chr10_-_90702490 4.515 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr5_-_39461054 3.964 NM_001343
DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr3_-_135575925 3.345 NM_016201
AMOTL2
angiomotin like 2
chr11_-_2127368 3.278 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr19_+_39664706 3.275 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr9_+_136673534 3.268 COL5A1
collagen, type V, alpha 1
chr4_-_186815116 2.899 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr1_-_27604656 2.415 WASF2
WAS protein family, member 2
chr6_-_128883125 2.152 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr6_-_75972286 2.131 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr14_+_75114692 2.049 NM_017791
FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr2_-_192420168 2.039 NM_004657
SDPR
serum deprivation response
chr10_-_17699309 1.933 PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr2_-_192419896 1.929 SDPR
serum deprivation response
chr15_+_61122139 1.899 TPM1
tropomyosin 1 (alpha)
chr5_-_138822475 1.869 NM_001077693
ECSCR
endothelial cell-specific chemotaxis regulator
chr12_-_45506001 1.776 NM_001143824
NM_018018
SLC38A4

solute carrier family 38, member 4

chr12_+_27568311 1.775 NM_001198915
NM_001198916
NM_003622
NM_177444
PPFIBP1



PTPRF interacting protein, binding protein 1 (liprin beta 1)



chr15_+_61121806 1.752 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
TPM1





tropomyosin 1 (alpha)





chr17_-_31104009 1.733 NM_139285
GAS2L2
growth arrest-specific 2 like 2
chr9_+_90339835 1.723 NM_001161625
NM_145283
NXNL2

nucleoredoxin-like 2

chr5_-_148422799 1.690 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr7_+_149699185 1.650 NM_014374
REPIN1
replication initiator 1
chrX_-_106129854 1.629 MORC4
MORC family CW-type zinc finger 4
chr19_-_43089073 1.577 NM_031951
WDR87
WD repeat domain 87
chr20_+_34603290 1.573 NM_006097
NM_181526
MYL9

myosin, light chain 9, regulatory

chr17_-_15495534 1.559 TRIM16
tripartite motif containing 16
chr11_-_8789457 1.546 NM_139157
ST5
suppression of tumorigenicity 5
chr17_-_37828643 1.533 NM_012232
PTRF
polymerase I and transcript release factor
chr20_+_34603311 1.521 MYL9
myosin, light chain 9, regulatory
chr1_-_24311212 1.520 NM_152372
MYOM3
myomesin family, member 3
chr3_-_115825742 1.505 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr6_+_123152044 1.504 SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr10_-_123346148 1.501 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr14_-_22516271 1.477 NM_198086
JUB
jub, ajuba homolog (Xenopus laevis)
chr14_-_22515725 1.420 JUB
jub, ajuba homolog (Xenopus laevis)
chr1_+_113018562 1.414 NM_001130079
NM_020963
MOV10

Mov10, Moloney leukemia virus 10, homolog (mouse)

chr1_+_238321794 1.382 NM_020066
FMN2
formin 2
chr9_+_88953378 1.355 NM_001001709
C9orf170
chromosome 9 open reading frame 170
chr6_+_83130220 1.332 TPBG
trophoblast glycoprotein
chr15_+_73728402 1.319 NM_153271
SNX33
sorting nexin 33
chr10_-_116382089 1.280 ABLIM1
actin binding LIM protein 1
chr8_+_70541412 1.270 NM_001128204
NM_015170
SULF1

sulfatase 1

chr12_-_94708641 1.252 NM_021229
NTN4
netrin 4
chr11_+_113671744 1.242 NM_006169
NNMT
nicotinamide N-methyltransferase
chr10_+_23768203 1.219 NM_001145373
OTUD1
OTU domain containing 1
chr4_-_186814852 1.210 SORBS2
sorbin and SH3 domain containing 2
chr1_+_183970093 1.202 NM_031935
HMCN1
hemicentin 1
chr2_+_113546365 1.179 NM_032556
IL1F10
interleukin 1 family, member 10 (theta)
chr10_+_91077581 1.177 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr11_-_6298284 1.170 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr2_-_160972606 1.162 RBMS1
RNA binding motif, single stranded interacting protein 1
chr15_+_37660568 1.160 NM_003246
THBS1
thrombospondin 1
chr2_+_102125616 1.147 IL1R1
interleukin 1 receptor, type I
chr10_-_125843092 1.143 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chrX_-_6156655 1.140 NM_181332
NLGN4X
neuroligin 4, X-linked
chr11_-_47427263 1.136 NM_005055
NM_032645
RAPSN

receptor-associated protein of the synapse

chr20_-_43608429 1.136 NM_181502
SPINLW1
serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin)
chr4_+_15089931 1.135 CC2D2A
coiled-coil and C2 domain containing 2A
chr7_+_72883128 1.123 NM_001305
CLDN4
claudin 4
chr1_+_181422016 1.120 LAMC2
laminin, gamma 2
chr6_-_75972473 1.091 COL12A1
collagen, type XII, alpha 1
chrX_-_114703273 1.090


chr1_-_43509187 1.072 EBNA1BP2
EBNA1 binding protein 2
chr5_-_20024050 1.071 NM_001167667
NM_004934
CDH18

cadherin 18, type 2

chr1_-_151788341 1.048 NM_002960
S100A3
S100 calcium binding protein A3
chr1_-_207892296 1.048 NM_001127641
LAMB3
laminin, beta 3
chr3_-_150569574 1.045 TM4SF1
transmembrane 4 L six family member 1
chr2_-_75641535 1.041 FAM176A
family with sequence similarity 176, member A
chr16_+_68765428 1.040 NM_173619
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr1_+_181421796 1.030 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr4_-_171247757 1.028 NM_016228
AADAT
aminoadipate aminotransferase
chr17_-_15463742 1.007 NM_006382
CDRT1
CMT1A duplicated region transcript 1
chr7_+_989321 1.007 NM_017781
CYP2W1
cytochrome P450, family 2, subfamily W, polypeptide 1
chr5_+_76150637 1.005 F2RL1
coagulation factor II (thrombin) receptor-like 1
chr19_-_41514390 1.000


chr10_+_24538094 0.998 KIAA1217
KIAA1217
chr9_+_112470871 0.993 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chr8_-_38505331 0.992 NM_207412
C8orf86
chromosome 8 open reading frame 86
chr2_-_75641587 0.989 NM_001135032
FAM176A
family with sequence similarity 176, member A
chr3_+_148609841 0.985 NM_003412
ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr11_+_93394025 0.980 NM_001098672
HEPHL1
hephaestin-like 1
chr1_-_54392030 0.980 NM_201546
CDCP2
CUB domain containing protein 2
chr16_-_73012740 0.975 NM_001011880
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr7_+_989472 0.970 CYP2W1
cytochrome P450, family 2, subfamily W, polypeptide 1
chr18_+_50646616 0.961 NM_004163
RAB27B
RAB27B, member RAS oncogene family
chr7_-_83116414 0.931 NM_012431
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr1_+_181421984 0.930 LAMC2
laminin, gamma 2
chr17_+_69941430 0.921 NM_018653
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr6_+_31190505 0.921 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr6_+_134251940 0.915 NM_198392
NM_003206
TCF21

transcription factor 21

chr22_+_40286957 0.914 NM_014460
CSDC2
cold shock domain containing C2, RNA binding
chrX_+_48505097 0.914 NM_001080489
GLOD5
glyoxalase domain containing 5
chr11_-_124311106 0.909 HEPACAM
hepatic and glial cell adhesion molecule
chr7_+_134114912 0.895 CALD1
caldesmon 1
chr7_+_134114701 0.893 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr4_+_158361185 0.892 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr13_+_48582389 0.881 NM_014923
FNDC3A
fibronectin type III domain containing 3A
chr15_+_42507123 0.881 CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr3_+_191588354 0.876 NM_006580
CLDN16
claudin 16
chr7_-_6441109 0.873 DAGLB
diacylglycerol lipase, beta
chr10_-_71576458 0.872 NM_001040273
NM_173555
TYSND1

trypsin domain containing 1

chr5_+_140160966 0.871 NM_018906
NM_031497
PCDHA3

protocadherin alpha 3

chr1_+_78126787 0.871 NM_001172309
NM_144573
NEXN

nexilin (F actin binding protein)

chr6_+_134251957 0.869 TCF21
transcription factor 21
chr12_+_2938703 0.859 NM_003213
NM_201441
NM_201443
TEAD4


TEA domain family member 4


chr12_+_6800950 0.851 NM_014449
NM_019858
GPR162

G protein-coupled receptor 162

chr1_-_207892420 0.843 NM_000228
LAMB3
laminin, beta 3
chr6_+_116956868 0.839 NM_153036
FAM26D
family with sequence similarity 26, member D
chr2_+_45732416 0.838 NM_005400
PRKCE
protein kinase C, epsilon
chr2_-_189752575 0.836 NM_000393
COL5A2
collagen, type V, alpha 2
chr10_+_24537725 0.834 NM_001098501
NM_019590
KIAA1217

KIAA1217

chr12_+_13044604 0.819 HTR7P1
5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
chr16_-_31054321 0.817 PRSS8
protease, serine, 8
chr6_+_84278971 0.813 PRSS35
protease, serine, 35
chr3_-_102878301 0.809 NM_014415
ZBTB11
zinc finger and BTB domain containing 11
chrX_+_53128207 0.796 NM_022117
TSPYL2
TSPY-like 2
chr10_-_71576415 0.786 TYSND1
trypsin domain containing 1
chr6_+_144040751 0.780 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr19_+_50041424 0.777 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr11_-_8788765 0.776 NM_213618
ST5
suppression of tumorigenicity 5
chr3_-_150533948 0.775 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr14_-_22974707 0.775 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr10_-_71576335 0.768


chr1_-_151848039 0.762 S100A16
S100 calcium binding protein A16
chr18_-_19496590 0.761 NM_173505
ANKRD29
ankyrin repeat domain 29
chr1_+_114323552 0.759 NM_020190
OLFML3
olfactomedin-like 3
chr22_-_34965945 0.745 NM_145637
APOL2
apolipoprotein L, 2
chr12_+_51728999 0.742 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr3_+_113061218 0.738 NM_001134439
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr19_-_56163815 0.734 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr11_-_85108030 0.732 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr16_-_31054563 0.731 NM_002773
PRSS8
protease, serine, 8
chr9_+_122923864 0.728 CEP110
centrosomal protein 110kDa
chr3_-_65999548 0.728 NM_001033057
NM_004742
NM_015520
MAGI1


membrane associated guanylate kinase, WW and PDZ domain containing 1


chr19_-_13910167 0.726 NM_024825
PODNL1
podocan-like 1
chr2_+_102456193 0.723 NM_001011552
SLC9A4
solute carrier family 9 (sodium/hydrogen exchanger), member 4
chr8_-_13018123 0.721 NM_001164271
DLC1
deleted in liver cancer 1
chr1_+_66990692 0.721 NM_152665
TCTEX1D1
Tctex1 domain containing 1
chr19_-_4468715 0.715 NM_001080400
PLIN4
perilipin 4
chr15_-_41904059 0.711 NM_005926
MFAP1
microfibrillar-associated protein 1
chr12_+_43972732 0.710 NM_001142678
ANO6
anoctamin 6
chr12_-_13044314 0.705 HEBP1
heme binding protein 1
chr6_-_42218692 0.705 NM_001164446
C6orf132
chromosome 6 open reading frame 132
chr11_-_85107569 0.703 NM_206929
SYTL2
synaptotagmin-like 2
chr1_-_148175345 0.695 MTMR11
myotubularin related protein 11
chr21_-_30614477 0.692 NM_203405
KRTAP26-1
keratin associated protein 26-1
chr8_-_42184194 0.687 PLAT
plasminogen activator, tissue
chr1_+_28637247 0.680 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr15_+_94670160 0.674 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr11_-_124311512 0.671 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr5_+_34723420 0.670 NM_001145523
RAI14
retinoic acid induced 14
chr12_-_13044448 0.669 HEBP1
heme binding protein 1
chr9_-_85342868 0.669 NM_174938
FRMD3
FERM domain containing 3
chr16_+_65790514 0.667 NM_024712
ELMO3
engulfment and cell motility 3
chr5_+_152850276 0.667 NM_000827
NM_001114183
GRIA1

glutamate receptor, ionotropic, AMPA 1

chr9_+_131123115 0.666 NM_001012715
C9orf106
chromosome 9 open reading frame 106
chr3_-_12858006 0.664 NM_000994
NM_001007073
RPL32

ribosomal protein L32

chr9_+_19039424 0.663 RRAGA
Ras-related GTP binding A
chr5_+_38882017 0.659 OSMR
oncostatin M receptor
chr3_+_171422908 0.655 NM_002740
PRKCI
protein kinase C, iota
chr15_+_66658626 0.655 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr2_+_218833982 0.654 NM_001077191
NM_001077194
NM_170699
GPBAR1


G protein-coupled bile acid receptor 1


chr1_-_16355013 0.647 NM_004431
EPHA2
EPH receptor A2
chr20_+_36365965 0.644 NM_001725
BPI
bactericidal/permeability-increasing protein
chr2_+_33554824 0.642 NM_001139488
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr16_+_68542310 0.641 NM_182619
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr2_+_95303947 0.640 PROM2
prominin 2
chr3_+_113061296 0.640 PHLDB2
pleckstrin homology-like domain, family B, member 2
chr15_-_93671314 0.639 LOC400456
hypothetical LOC400456
chr12_-_13044467 0.639 NM_015987
HEBP1
heme binding protein 1
chr15_+_42507057 0.634 CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr3_+_50281582 0.633 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr2_+_95303922 0.631 NM_001165977
NM_001165978
NM_144707
PROM2


prominin 2


chr14_+_20527804 0.628 NM_001029991
NM_022734
METTL17

methyltransferase like 17

chr2_+_102169864 0.627 NM_003854
IL1RL2
interleukin 1 receptor-like 2
chr5_+_121493113 0.623 NM_207317
ZNF474
zinc finger protein 474
chrX_+_37315740 0.622 NM_001170331
NM_198511
LANCL3

LanC lantibiotic synthetase component C-like 3 (bacterial)

chr1_-_148175383 0.615 NM_001145862
MTMR11
myotubularin related protein 11
chr16_+_68542126 0.614 NM_001136214
CLEC18A
C-type lectin domain family 18, member A
chr17_+_42641712 0.612 NM_002476
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr1_+_216585298 0.602 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr19_+_49337568 0.601 ZNF234
zinc finger protein 234
chr5_-_151046638 0.599 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr17_+_45404677 0.599 DLX4
distal-less homeobox 4
chr3_+_9919295 0.592 NM_153483
IL17RE
interleukin 17 receptor E
chr19_-_13478037 0.590 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr15_-_97366313 0.588 NM_001102612
PGPEP1L
pyroglutamyl-peptidase I-like
chr7_+_134114957 0.587 CALD1
caldesmon 1
chr1_+_17817397 0.587 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr12_-_78608873 0.585 NM_002583
PAWR
PRKC, apoptosis, WT1, regulator
chr10_+_102782151 0.584 SFXN3
sideroflexin 3
chr6_+_34590624 0.584 PACSIN1
protein kinase C and casein kinase substrate in neurons 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.80 7.43e-04 GO:0048468 cell development
1.37 2.06e-03 GO:0048856 anatomical structure development
2.81 2.60e-03 GO:0007517 muscle organ development
1.85 2.62e-03 GO:0007155 cell adhesion
1.85 2.62e-03 GO:0022610 biological adhesion
1.39 2.66e-03 GO:0048731 system development
3.25 6.68e-03 GO:0014706 striated muscle tissue development
2.37 1.27e-02 GO:0061061 muscle structure development
2.97 2.68e-02 GO:0060537 muscle tissue development
2.37 4.56e-02 GO:0040007 growth

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.58 9.83e-07 GO:0005576 extracellular region
1.31 1.39e-04 GO:0071944 cell periphery
1.46 2.03e-04 GO:0044459 plasma membrane part
1.30 4.15e-04 GO:0005886 plasma membrane
15.96 8.42e-04 GO:0001527 microfibril
3.22 2.27e-03 GO:0044420 extracellular matrix part
2.21 6.70e-03 GO:0015629 actin cytoskeleton
2.46 2.37e-02 GO:0031252 cell leading edge
1.55 2.68e-02 GO:0044421 extracellular region part
9.58 2.96e-02 GO:0043205 fibril

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.43 1.09e-04 GO:0003779 actin binding
2.04 2.31e-04 GO:0008092 cytoskeletal protein binding
3.42 6.65e-04 GO:0008201 heparin binding
1.83 2.32e-03 GO:0005509 calcium ion binding
2.85 4.65e-03 GO:0005539 glycosaminoglycan binding
4.90 4.76e-03 GO:0008307 structural constituent of muscle
2.75 5.17e-03 GO:0001871 pattern binding
2.75 5.17e-03 GO:0030247 polysaccharide binding
1.17 6.16e-03 GO:0005515 protein binding
3.04 1.99e-02 GO:0019838 growth factor binding