Motif ID: ZFP161.p2

Z-value: 1.829


Transcription factors associated with ZFP161.p2:

Gene SymbolEntrez IDGene Name
ZFP161 7541 zinc finger protein 161 homolog (mouse)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZFP161chr18_-_52860130.674.3e-03Click!


Activity profile for motif ZFP161.p2.

activity profile for motif ZFP161.p2


Sorted Z-values histogram for motif ZFP161.p2

Sorted Z-values for motif ZFP161.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZFP161.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_-_30072329 3.020 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr22_-_30072217 2.492 NM_014323
NM_032050
NM_032051
NM_032052
PATZ1



POZ (BTB) and AT hook containing zinc finger 1



chr2_+_207016525 2.198 NM_003812
ADAM23
ADAM metallopeptidase domain 23
chr8_+_1937711 2.175 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr17_-_19711580 1.866 NM_001142610
NM_014683
ULK2

unc-51-like kinase 2 (C. elegans)

chr22_-_30071761 1.663 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr8_-_125809831 1.575 NM_014751
MTSS1
metastasis suppressor 1
chr15_+_97462675 1.493 NM_015286
NM_145728
SYNM

synemin, intermediate filament protein

chr11_+_57191887 1.412 ZDHHC5
zinc finger, DHHC-type containing 5
chr22_-_30071565 1.263 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr2_+_171280944 1.259 SP5
Sp5 transcription factor
chr17_+_41327808 1.247 MAPT
microtubule-associated protein tau
chr1_-_212791597 1.220 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr13_+_32058537 1.220 NM_015032
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr9_-_21984414 1.196 NM_058195
CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr2_+_10969513 1.164 NM_002236
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr10_-_30065760 1.143 SVIL
supervillin
chr18_+_75825563 1.137 NM_001136180
HSBP1L1
heat shock factor binding protein 1-like 1
chr15_-_61680003 1.134 LOC100130855
hypothetical LOC100130855
chr13_-_76358433 1.104 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr8_+_143805595 1.092 NM_016647
C8orf55
chromosome 8 open reading frame 55
chr13_+_32058610 1.079 PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr2_+_56264627 1.077 NM_001080433
CCDC85A
coiled-coil domain containing 85A
chr10_+_129595349 1.077 PTPRE
protein tyrosine phosphatase, receptor type, E
chr10_+_129595289 1.074 NM_006504
PTPRE
protein tyrosine phosphatase, receptor type, E
chr17_+_41327449 1.067 NM_001123066
NM_001123067
NM_005910
NM_016834
NM_016835
NM_016841
MAPT





microtubule-associated protein tau





chr16_-_11798507 1.046 ZC3H7A
zinc finger CCCH-type containing 7A
chr18_-_5286013 1.028 NM_001143823
NM_003409
ZFP161

zinc finger protein 161 homolog (mouse)

chr15_+_29406335 1.021 NM_015995
KLF13
Kruppel-like factor 13
chr13_-_76358370 1.013 KCTD12
potassium channel tetramerisation domain containing 12
chr14_-_92869113 1.013 BTBD7
BTB (POZ) domain containing 7
chr10_+_90629880 1.011 NM_020799
STAMBPL1
STAM binding protein-like 1
chr17_-_77649322 1.001 FASN
fatty acid synthase
chr17_+_41327662 0.995 MAPT
microtubule-associated protein tau
chr17_-_77649393 0.986 NM_004104
FASN
fatty acid synthase
chr13_+_32058630 0.972 PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr14_+_103674812 0.972 NM_015656
KIF26A
kinesin family member 26A
chr12_+_67488246 0.949 MDM2
Mdm2 p53 binding protein homolog (mouse)
chr18_-_21184824 0.945


chr8_+_30361485 0.943 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr2_+_149895274 0.940 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chrX_-_19815526 0.939 SH3KBP1
SH3-domain kinase binding protein 1
chr13_+_32058651 0.939 PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr21_+_32167175 0.925 NM_014586
HUNK
hormonally up-regulated Neu-associated kinase
chr14_-_104706159 0.919 NM_002226
NM_145159
JAG2

jagged 2

chr17_+_41327792 0.912 MAPT
microtubule-associated protein tau
chr5_-_146869613 0.908 DPYSL3
dihydropyrimidinase-like 3
chr11_+_57192132 0.906 ZDHHC5
zinc finger, DHHC-type containing 5
chr11_+_915874 0.903 AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr3_-_53054999 0.898 SFMBT1
Scm-like with four mbt domains 1
chr12_+_50271283 0.891 NM_014191
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr19_-_5291700 0.888 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr1_+_9571518 0.886 NM_001010866
NM_001130924
TMEM201

transmembrane protein 201

chr14_-_64948998 0.881 LOC645431
hypothetical LOC645431
chr1_-_1274618 0.872 DVL1
dishevelled, dsh homolog 1 (Drosophila)
chr19_-_52426055 0.870 NM_014417
BBC3
BCL2 binding component 3
chr3_+_58452560 0.862 NM_001128214
KCTD6
potassium channel tetramerisation domain containing 6
chr8_+_28615062 0.860 NM_001440
EXTL3
exostoses (multiple)-like 3
chr11_+_17697685 0.858 NM_002478
MYOD1
myogenic differentiation 1
chr11_+_915795 0.855 NM_012305
AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr5_-_146869811 0.841 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr10_+_105027431 0.839 INA
internexin neuronal intermediate filament protein, alpha
chr7_-_35044177 0.837 NM_015283
DPY19L1
dpy-19-like 1 (C. elegans)
chr9_-_21984379 0.829 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr20_-_34925483 0.821 NM_080627
KIAA0889
KIAA0889
chr9_-_71476917 0.816 NM_001163
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr20_+_5055393 0.815 NM_003818
CDS2
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr11_+_86426518 0.812 NM_001168724
NM_022918
TMEM135

transmembrane protein 135

chr2_-_39040981 0.805 LOC375196
hypothetical LOC375196
chr11_+_915899 0.803 AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr4_-_83570318 0.801 NM_031372
HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr20_+_5055653 0.800 CDS2
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr8_-_125809559 0.798 MTSS1
metastasis suppressor 1
chr9_-_85342868 0.797 NM_174938
FRMD3
FERM domain containing 3
chr12_+_93066370 0.796 NM_005761
PLXNC1
plexin C1
chr4_-_83569853 0.787 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr14_+_73128162 0.780 NM_152331
ACOT4
acyl-CoA thioesterase 4
chr4_+_109072120 0.779 NM_183075
CYP2U1
cytochrome P450, family 2, subfamily U, polypeptide 1
chr9_-_21984329 0.773 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr16_+_19087035 0.773 NM_016524
SYT17
synaptotagmin XVII
chr6_-_16869579 0.772 NM_000332
NM_001128164
ATXN1

ataxin 1

chr11_-_61341011 0.769 NM_013402
FADS1
fatty acid desaturase 1
chr11_+_65594361 0.763 NM_018026
PACS1
phosphofurin acidic cluster sorting protein 1
chr11_+_46325457 0.762 NM_003646
DGKZ
diacylglycerol kinase, zeta
chr3_-_53055078 0.755 NM_001005158
NM_016329
SFMBT1

Scm-like with four mbt domains 1

chr8_+_28614929 0.752 EXTL3
exostoses (multiple)-like 3
chr3_+_152287365 0.752 NM_053002
MED12L
mediator complex subunit 12-like
chr14_+_68796433 0.751 NM_001168368
NM_020692
GALNTL1

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1

chr7_+_79602023 0.748 NM_002069
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr4_+_145786622 0.745 NM_022475
HHIP
hedgehog interacting protein
chr6_+_17210467 0.744 NM_001190766
FLJ23152
hypothetical protein LOC401236
chr3_-_181237210 0.736 NM_016559
PEX5L
peroxisomal biogenesis factor 5-like
chr9_-_139316523 0.731 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr2_+_96845704 0.721 NM_017623
NM_199078
CNNM3

cyclin M3

chr3_+_144321286 0.720 NM_004267
CHST2
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr17_-_19589363 0.707 NM_001135168
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chrX_-_46503415 0.700 NM_032591
SLC9A7
solute carrier family 9 (sodium/hydrogen exchanger), member 7
chr6_+_107917965 0.696 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr7_-_5536704 0.686 NM_001101
ACTB
actin, beta
chr11_-_64368616 0.682 NM_017525
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr16_-_71639670 0.678 NM_006885
ZFHX3
zinc finger homeobox 3
chr11_+_1925075 0.671 NM_021134
MRPL23
mitochondrial ribosomal protein L23
chr12_+_67488112 0.671 NM_002392
MDM2
Mdm2 p53 binding protein homolog (mouse)
chr1_-_212791467 0.668 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr2_+_71547325 0.666 NM_001130455
NM_001130982
NM_001130983
NM_001130984
NM_001130985
NM_001130986
NM_001130987
DYSF






dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)






chr8_-_143748324 0.664 JRK
jerky homolog (mouse)
chr3_-_55496370 0.662 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr6_-_5952631 0.661 NM_016588
NRN1
neuritin 1
chr18_+_17076166 0.659 NM_001142966
GREB1L
growth regulation by estrogen in breast cancer-like
chr14_+_68796621 0.658 GALNTL1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr1_+_9217444 0.658 NM_004285
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chrX_-_19815370 0.657 SH3KBP1
SH3-domain kinase binding protein 1
chr12_-_123617962 0.656 NM_001077261
NM_006312
NCOR2

nuclear receptor corepressor 2

chr19_+_18391423 0.655


chr3_-_109292444 0.653 NM_001777
NM_198793
CD47

CD47 molecule

chr10_+_122206455 0.649 NM_001030059
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr17_+_75689894 0.647 NM_000152
NM_001079803
NM_001079804
GAA


glucosidase, alpha; acid


chr20_-_3336586 0.644 C20orf194
chromosome 20 open reading frame 194
chr12_+_6745947 0.643 PTMS
parathymosin
chr5_-_101659864 0.643 NM_180991
SLCO4C1
solute carrier organic anion transporter family, member 4C1
chr11_+_57192034 0.641 NM_015457
ZDHHC5
zinc finger, DHHC-type containing 5
chr10_-_35970363 0.640 NM_031866
FZD8
frizzled homolog 8 (Drosophila)
chr11_+_113435506 0.639 ZBTB16
zinc finger and BTB domain containing 16
chr3_-_120236118 0.633 IGSF11
immunoglobulin superfamily, member 11
chr11_-_1549719 0.631 NM_004420
DUSP8
dual specificity phosphatase 8
chr2_+_56265260 0.630


chr3_+_61522310 0.628 PTPRG
protein tyrosine phosphatase, receptor type, G
chr7_-_27136876 0.621 NM_002141
HOXA4
homeobox A4
chr19_-_18867868 0.620 NM_021267
NM_198207
NM_001492
LASS1

GDF1
LAG1 homolog, ceramide synthase 1

growth differentiation factor 1
chr3_+_195688974 0.618 FLJ34208
hypothetical LOC401106
chr17_-_24918052 0.616 NM_198147
ABHD15
abhydrolase domain containing 15
chr9_-_125070675 0.613 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr22_+_23149855 0.613 ADORA2A
adenosine A2a receptor
chr3_+_171558143 0.612 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr1_-_10677051 0.610 CASZ1
castor zinc finger 1
chr9_-_131845277 0.609 NM_015033
FNBP1
formin binding protein 1
chr14_-_104705753 0.606 JAG2
jagged 2
chr10_-_105604942 0.606 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr5_-_88215034 0.606 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr22_-_27405708 0.602 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr10_+_123913094 0.602 NM_006997
NM_206860
TACC2

transforming, acidic coiled-coil containing protein 2

chr18_-_11138760 0.598 NM_022068
FAM38B
family with sequence similarity 38, member B
chr9_-_125070613 0.593 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr2_-_192767844 0.593 NM_016192
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr14_-_73106243 0.592


chr22_+_29420792 0.590 NM_030758
OSBP2
oxysterol binding protein 2
chr13_-_27967215 0.590 NM_001159920
NM_001160030
NM_001160031
NM_002019
FLT1



fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)



chr13_-_43259032 0.589 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr11_+_66643311 0.589 NM_012308
KDM2A
lysine (K)-specific demethylase 2A
chr17_+_4434582 0.588 NM_001114974
SMTNL2
smoothelin-like 2
chr7_+_148590152 0.588 NM_001195220
ZNF783
zinc finger family member 783
chr3_+_61522219 0.587 NM_002841
PTPRG
protein tyrosine phosphatase, receptor type, G
chr14_-_92869124 0.583 NM_001002860
NM_018167
BTBD7

BTB (POZ) domain containing 7

chr12_+_6745729 0.582 NM_002824
PTMS
parathymosin
chr2_-_233501069 0.581 NM_001114090
NGEF
neuronal guanine nucleotide exchange factor
chr7_+_150387578 0.579 NM_003040
SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr2_+_25118417 0.578 NM_014971
EFR3B
EFR3 homolog B (S. cerevisiae)
chr4_-_39655944 0.577 NM_001100399
NM_001100400
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr1_+_226937732 0.576 RHOU
ras homolog gene family, member U
chr5_+_75734759 0.574 NM_006633
IQGAP2
IQ motif containing GTPase activating protein 2
chr17_+_45008175 0.574 NM_007225
NXPH3
neurexophilin 3
chr12_+_6745835 0.572 PTMS
parathymosin
chr5_-_83716346 0.571 NM_005711
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr10_+_105243724 0.570 NM_004210
NEURL
neuralized homolog (Drosophila)
chr5_+_1061900 0.565 NM_033120
NKD2
naked cuticle homolog 2 (Drosophila)
chr8_+_99508425 0.563 NM_020697
KCNS2
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
chr11_+_120828058 0.561 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr5_-_14924555 0.560 NM_054027
ANKH
ankylosis, progressive homolog (mouse)
chr5_-_142763252 0.557 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr7_-_47588266 0.554 TNS3
tensin 3
chr7_-_5535726 0.553 ACTB
actin, beta
chr5_+_14493905 0.552 TRIO
triple functional domain (PTPRF interacting)
chr12_-_83830670 0.552 SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr11_+_120828275 0.551 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr2_-_218865451 0.550 NM_022152
TMBIM1
transmembrane BAX inhibitor motif containing 1
chr11_+_916021 0.547 AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr20_+_8060762 0.547 NM_015192
NM_182734
PLCB1

phospholipase C, beta 1 (phosphoinositide-specific)

chr9_-_16860719 0.547 NM_017637
BNC2
basonuclin 2
chr8_+_61753793 0.546 NM_017780
CHD7
chromodomain helicase DNA binding protein 7
chr8_+_28407613 0.542 NM_017412
FZD3
frizzled homolog 3 (Drosophila)
chr8_-_60194099 0.541 NM_014729
TOX
thymocyte selection-associated high mobility group box
chr5_-_171547700 0.537 STK10
serine/threonine kinase 10
chr17_-_59131194 0.537 LIMD2
LIM domain containing 2
chr10_-_17699371 0.536 NM_014241
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr19_+_58733144 0.534 NM_001079906
ZNF331
zinc finger protein 331
chr5_-_171547804 0.534 STK10
serine/threonine kinase 10
chr7_+_65307816 0.534 TPST1
tyrosylprotein sulfotransferase 1
chr11_-_60819110 0.533 VWCE
von Willebrand factor C and EGF domains
chr4_+_7245218 0.533 NM_020777
SORCS2
sortilin-related VPS10 domain containing receptor 2
chr22_-_41913076 0.530 NM_015140
TTLL12
tubulin tyrosine ligase-like family, member 12
chrX_-_19815586 0.530 NM_031892
SH3KBP1
SH3-domain kinase binding protein 1
chr10_+_123912930 0.528 TACC2
transforming, acidic coiled-coil containing protein 2
chrX_-_74062005 0.526 NM_001008537
KIAA2022
KIAA2022
chr9_+_33807168 0.525 NM_017811
UBE2R2
ubiquitin-conjugating enzyme E2R 2
chr20_-_56523251 0.525 NM_153360
APCDD1L
adenomatosis polyposis coli down-regulated 1-like
chr19_-_2378581 0.523 TIMM13
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr19_-_14108400 0.521 NM_018154
ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr7_-_47588652 0.519 TNS3
tensin 3
chr2_+_29191711 0.515 NM_024692
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr1_+_224477941 0.514 NM_031944
MIXL1
Mix1 homeobox-like 1 (Xenopus laevis)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.32 2.16e-16 GO:0007275 multicellular organismal development
1.30 1.06e-15 GO:0032502 developmental process
1.52 1.27e-15 GO:0007399 nervous system development
1.19 2.58e-15 GO:0050794 regulation of cellular process
1.17 5.02e-14 GO:0050789 regulation of biological process
1.32 1.15e-12 GO:0048731 system development
1.45 7.94e-12 GO:0009653 anatomical structure morphogenesis
1.15 9.67e-12 GO:0065007 biological regulation
1.29 1.94e-11 GO:0048856 anatomical structure development
1.37 2.11e-11 GO:0048869 cellular developmental process
1.37 2.81e-11 GO:0030154 cell differentiation
1.58 5.66e-11 GO:0022008 neurogenesis
1.58 1.77e-10 GO:0048699 generation of neurons
1.22 3.72e-10 GO:0044260 cellular macromolecule metabolic process
1.34 1.73e-09 GO:0048523 negative regulation of cellular process
1.51 4.26e-09 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.64 4.35e-09 GO:0007167 enzyme linked receptor protein signaling pathway
1.16 6.95e-09 GO:0044237 cellular metabolic process
1.30 7.41e-09 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.09 1.59e-08 GO:0009987 cellular process
1.40 2.02e-08 GO:0009966 regulation of signal transduction
1.60 2.39e-08 GO:0045595 regulation of cell differentiation
1.29 2.69e-08 GO:0010556 regulation of macromolecule biosynthetic process
1.24 3.07e-08 GO:0060255 regulation of macromolecule metabolic process
1.50 4.90e-08 GO:0050793 regulation of developmental process
1.51 6.70e-08 GO:0006351 transcription, DNA-dependent
1.36 8.08e-08 GO:0023051 regulation of signaling
1.87 9.10e-08 GO:0060284 regulation of cell development
1.27 1.96e-07 GO:0010468 regulation of gene expression
1.28 2.11e-07 GO:0048522 positive regulation of cellular process
1.27 2.14e-07 GO:0031326 regulation of cellular biosynthetic process
1.29 2.21e-07 GO:0048519 negative regulation of biological process
1.26 2.70e-07 GO:0009889 regulation of biosynthetic process
1.22 3.49e-07 GO:0031323 regulation of cellular metabolic process
1.26 7.22e-07 GO:0048518 positive regulation of biological process
1.22 8.82e-07 GO:0080090 regulation of primary metabolic process
1.72 9.31e-07 GO:0009968 negative regulation of signal transduction
1.52 1.08e-06 GO:2000026 regulation of multicellular organismal development
1.63 1.62e-06 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.53 1.96e-06 GO:0009790 embryo development
1.91 3.13e-06 GO:0050767 regulation of neurogenesis
1.25 3.32e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45 3.41e-06 GO:0048468 cell development
1.60 5.59e-06 GO:0045892 negative regulation of transcription, DNA-dependent
1.59 7.25e-06 GO:0051253 negative regulation of RNA metabolic process
1.27 7.55e-06 GO:0006355 regulation of transcription, DNA-dependent
1.27 7.66e-06 GO:0051252 regulation of RNA metabolic process
1.54 9.51e-06 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.75 9.52e-06 GO:0045597 positive regulation of cell differentiation
1.51 9.72e-06 GO:0009890 negative regulation of biosynthetic process
1.19 9.89e-06 GO:0019222 regulation of metabolic process
1.53 1.03e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
1.82 1.31e-05 GO:0051960 regulation of nervous system development
1.14 1.40e-05 GO:0044238 primary metabolic process
1.12 1.41e-05 GO:0008152 metabolic process
1.51 1.68e-05 GO:0031327 negative regulation of cellular biosynthetic process
1.64 1.86e-05 GO:0023057 negative regulation of signaling
1.21 1.95e-05 GO:0016043 cellular component organization
1.53 2.18e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.63 2.19e-05 GO:0010648 negative regulation of cell communication
1.29 2.54e-05 GO:0006464 protein modification process
1.41 2.56e-05 GO:0006793 phosphorus metabolic process
1.41 2.56e-05 GO:0006796 phosphate metabolic process
1.53 2.68e-05 GO:0010629 negative regulation of gene expression
1.41 3.05e-05 GO:0032774 RNA biosynthetic process
1.23 3.32e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.49 3.84e-05 GO:0030182 neuron differentiation
1.74 5.03e-05 GO:0022603 regulation of anatomical structure morphogenesis
1.67 5.21e-05 GO:0043009 chordate embryonic development
1.52 5.66e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
1.60 8.06e-05 GO:0051094 positive regulation of developmental process
1.64 8.31e-05 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.65 1.04e-04 GO:0009792 embryo development ending in birth or egg hatching
1.40 1.23e-04 GO:0042127 regulation of cell proliferation
1.56 1.26e-04 GO:0007417 central nervous system development
1.27 1.44e-04 GO:0043412 macromolecule modification
1.15 1.51e-04 GO:0043170 macromolecule metabolic process
1.49 1.55e-04 GO:0032989 cellular component morphogenesis
1.19 1.55e-04 GO:0071840 cellular component organization or biogenesis
2.25 1.79e-04 GO:0010720 positive regulation of cell development
1.57 1.82e-04 GO:0072358 cardiovascular system development
1.57 1.82e-04 GO:0072359 circulatory system development
1.42 1.89e-04 GO:0051128 regulation of cellular component organization
1.27 2.29e-04 GO:0048583 regulation of response to stimulus
1.44 3.22e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.49 3.53e-04 GO:0009887 organ morphogenesis
1.54 3.60e-04 GO:0032990 cell part morphogenesis
1.22 4.73e-04 GO:0071842 cellular component organization at cellular level
1.49 4.73e-04 GO:0000902 cell morphogenesis
1.50 5.06e-04 GO:0048666 neuron development
1.17 5.71e-04 GO:0023052 signaling
1.37 5.78e-04 GO:0009892 negative regulation of metabolic process
1.28 5.83e-04 GO:0034645 cellular macromolecule biosynthetic process
2.08 5.85e-04 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.53 6.22e-04 GO:0031175 neuron projection development
1.53 6.68e-04 GO:0048585 negative regulation of response to stimulus
1.53 6.68e-04 GO:0048858 cell projection morphogenesis
1.18 7.51e-04 GO:0007165 signal transduction
1.41 7.56e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.27 7.74e-04 GO:0009059 macromolecule biosynthetic process
2.06 7.84e-04 GO:0022604 regulation of cell morphogenesis
1.38 8.64e-04 GO:0031324 negative regulation of cellular metabolic process
1.55 1.17e-03 GO:0048812 neuron projection morphogenesis
1.45 1.20e-03 GO:0030030 cell projection organization
1.33 1.22e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.20 1.88e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.81 2.00e-03 GO:0045664 regulation of neuron differentiation
1.37 2.28e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.43 2.29e-03 GO:0010628 positive regulation of gene expression
1.41 2.54e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.49 3.77e-03 GO:0000904 cell morphogenesis involved in differentiation
1.54 3.89e-03 GO:0007409 axonogenesis
1.91 4.30e-03 GO:0031344 regulation of cell projection organization
1.44 4.38e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.15 4.81e-03 GO:0051716 cellular response to stimulus
1.29 5.04e-03 GO:0035556 intracellular signal transduction
1.42 5.06e-03 GO:0051254 positive regulation of RNA metabolic process
1.29 5.60e-03 GO:0051239 regulation of multicellular organismal process
1.19 5.63e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.53 5.88e-03 GO:0008285 negative regulation of cell proliferation
1.37 7.04e-03 GO:0016310 phosphorylation
1.22 7.13e-03 GO:0090304 nucleic acid metabolic process
1.36 7.99e-03 GO:0040011 locomotion
1.51 8.21e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.36 8.50e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.29 8.86e-03 GO:0009893 positive regulation of metabolic process
1.30 1.05e-02 GO:0031325 positive regulation of cellular metabolic process
1.63 1.16e-02 GO:0035295 tube development
1.48 1.20e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.73 1.23e-02 GO:0001701 in utero embryonic development
1.24 1.26e-02 GO:0016070 RNA metabolic process
1.23 1.29e-02 GO:0048513 organ development
1.31 1.65e-02 GO:0010646 regulation of cell communication
1.48 1.73e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.94 1.78e-02 GO:0010975 regulation of neuron projection development
1.35 1.84e-02 GO:0009891 positive regulation of biosynthetic process
1.50 1.90e-02 GO:0040008 regulation of growth
2.06 2.02e-02 GO:0003007 heart morphogenesis
1.50 2.24e-02 GO:0016477 cell migration
2.17 2.41e-02 GO:0050769 positive regulation of neurogenesis
1.23 2.43e-02 GO:0007166 cell surface receptor linked signaling pathway
2.64 2.44e-02 GO:0001570 vasculogenesis
1.66 2.56e-02 GO:0007507 heart development
1.19 2.73e-02 GO:0009058 biosynthetic process
1.19 2.85e-02 GO:0044249 cellular biosynthetic process
1.16 3.52e-02 GO:0006807 nitrogen compound metabolic process
1.57 3.83e-02 GO:0051130 positive regulation of cellular component organization
1.46 3.88e-02 GO:0048870 cell motility
1.46 3.88e-02 GO:0051674 localization of cell
1.58 3.93e-02 GO:0006366 transcription from RNA polymerase II promoter
1.52 3.93e-02 GO:0007420 brain development
1.18 4.65e-02 GO:0044267 cellular protein metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.11 1.11e-16 GO:0044424 intracellular part
1.11 4.38e-16 GO:0005622 intracellular
1.21 8.84e-14 GO:0005634 nucleus
1.14 4.08e-13 GO:0043227 membrane-bounded organelle
1.14 4.47e-13 GO:0043231 intracellular membrane-bounded organelle
1.11 2.81e-11 GO:0043229 intracellular organelle
1.11 2.81e-11 GO:0043226 organelle
1.13 6.71e-10 GO:0005737 cytoplasm
1.28 8.55e-06 GO:0031981 nuclear lumen
1.25 9.13e-06 GO:0044428 nuclear part
1.32 2.12e-05 GO:0005654 nucleoplasm
1.23 1.08e-04 GO:0070013 intracellular organelle lumen
1.04 1.14e-04 GO:0044464 cell part
1.04 1.20e-04 GO:0005623 cell
1.22 1.94e-04 GO:0031974 membrane-enclosed lumen
1.22 2.41e-04 GO:0043233 organelle lumen
1.38 1.55e-03 GO:0044451 nucleoplasm part
1.19 1.36e-02 GO:0005829 cytosol
1.10 2.20e-02 GO:0044446 intracellular organelle part
1.43 3.65e-02 GO:0043005 neuron projection
1.10 4.11e-02 GO:0044422 organelle part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.10 5.35e-16 GO:0005488 binding
1.16 2.07e-12 GO:0005515 protein binding
1.52 5.29e-11 GO:0030528 transcription regulator activity
1.49 1.48e-09 GO:0001071 nucleic acid binding transcription factor activity
1.49 1.48e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
1.54 1.49e-07 GO:0043565 sequence-specific DNA binding
1.99 1.09e-04 GO:0003714 transcription corepressor activity
1.83 2.32e-04 GO:0010843 promoter binding
1.81 2.48e-04 GO:0000975 regulatory region DNA binding
1.81 2.48e-04 GO:0001067 regulatory region nucleic acid binding
1.81 2.48e-04 GO:0044212 transcription regulatory region DNA binding
1.21 1.21e-03 GO:0003677 DNA binding
1.17 1.22e-03 GO:0003676 nucleic acid binding
1.54 1.55e-03 GO:0000988 protein binding transcription factor activity
1.54 1.55e-03 GO:0000989 transcription factor binding transcription factor activity
1.50 1.69e-03 GO:0019904 protein domain specific binding
1.53 2.43e-03 GO:0003712 transcription cofactor activity
4.76 2.86e-03 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity
1.55 3.71e-03 GO:0042578 phosphoric ester hydrolase activity
1.64 4.44e-03 GO:0016791 phosphatase activity
1.40 5.13e-03 GO:0004672 protein kinase activity
2.15 5.33e-03 GO:0019199 transmembrane receptor protein kinase activity
1.79 5.91e-03 GO:0004721 phosphoprotein phosphatase activity
1.35 1.17e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.33 2.04e-02 GO:0016301 kinase activity
1.33 2.05e-02 GO:0019899 enzyme binding
1.18 2.18e-02 GO:0000166 nucleotide binding
1.54 2.27e-02 GO:0008134 transcription factor binding
1.52 3.20e-02 GO:0016564 transcription repressor activity