Motif ID: FOSL2.p2

Z-value: 1.446


Transcription factors associated with FOSL2.p2:

Gene SymbolEntrez IDGene Name
FOSL2 2355 FOS-like antigen 2



Activity profile for motif FOSL2.p2.

activity profile for motif FOSL2.p2


Sorted Z-values histogram for motif FOSL2.p2

Sorted Z-values for motif FOSL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOSL2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_72883128 3.023 NM_001305
CLDN4
claudin 4
chr17_-_35975227 2.552 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr6_-_31853027 2.455 NM_025258
C6orf27
chromosome 6 open reading frame 27
chr6_-_149847718 2.430 ZC3H12D
zinc finger CCCH-type containing 12D
chr7_+_128367961 2.324 NM_001098627
IRF5
interferon regulatory factor 5
chr6_-_149847809 2.310 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr19_+_40895669 2.131 NM_014383
ZBTB32
zinc finger and BTB domain containing 32
chr16_+_28413421 1.894 NM_018690
APOBR
apolipoprotein B receptor
chrX_-_154216929 1.817 NM_001289
CLIC2
chloride intracellular channel 2
chr17_+_7423662 1.791 CD68
CD68 molecule
chr17_+_7423685 1.661 CD68
CD68 molecule
chr20_-_51633042 1.573 NM_006526
ZNF217
zinc finger protein 217
chr1_+_154351082 1.569 NM_005572
NM_170707
NM_170708
LMNA


lamin A/C


chr22_+_21370394 1.567 IGL@
immunoglobulin lambda locus
chr11_+_2881080 1.536 SLC22A18
solute carrier family 22, member 18
chr1_+_207995999 1.481 NM_025228
TRAF3IP3
TRAF3 interacting protein 3
chr17_+_72958207 1.480 NM_001113496
SEPT9
septin 9
chr8_-_42742729 1.443 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chr19_+_4180494 1.435 NM_005755
EBI3
Epstein-Barr virus induced 3
chr16_+_48857962 1.366 ADCY7
adenylate cyclase 7
chr17_-_53764867 1.357


chr15_+_57691382 1.336 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr19_-_6621078 1.306 TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr17_+_7423704 1.295 CD68
CD68 molecule
chr15_+_57691272 1.284 NM_004751
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr16_+_51690564 1.268 CHD9
chromodomain helicase DNA binding protein 9
chr16_+_57091546 1.268 NDRG4
NDRG family member 4
chr16_-_11918019 1.254 NM_001130007
GSPT1
G1 to S phase transition 1
chr2_-_152538694 1.251 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr19_-_6621598 1.235 NM_003807
NM_172014
TNFSF14

tumor necrosis factor (ligand) superfamily, member 14

chr1_+_154351162 1.232 LMNA
lamin A/C
chr1_+_173111306 1.228 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr12_+_54910767 1.206 NM_001135195
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr22_+_43451600 1.199 PRR5
proline rich 5 (renal)
chr17_+_72958330 1.151 SEPT9
septin 9
chr1_-_159099090 1.143 NM_001166663
NM_001166664
NM_016382
CD244


CD244 molecule, natural killer cell receptor 2B4


chr9_-_122728173 1.123 TRAF1
TNF receptor-associated factor 1
chr4_-_977163 1.119 NM_022042
NM_134425
NM_213613
SLC26A1


solute carrier family 26 (sulfate transporter), member 1


chr11_-_118571793 1.082 NM_001145018
CCDC153
coiled-coil domain containing 153
chr12_+_110689094 1.072 ALDH2
aldehyde dehydrogenase 2 family (mitochondrial)
chr9_+_4829763 1.039 RCL1
RNA terminal phosphate cyclase-like 1
chr20_-_581808 1.036 SRXN1
sulfiredoxin 1
chr14_-_23847000 1.033 CIDEB
cell death-inducing DFFA-like effector b
chr11_+_10433241 1.023 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr3_-_8668723 1.020 NM_015931
C3orf32
chromosome 3 open reading frame 32
chr20_-_581844 1.011 NM_080725
SRXN1
sulfiredoxin 1
chrX_+_115481848 0.997 SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr3_-_180460372 0.993 NM_171829
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr5_-_138746917 0.985 NM_005847
NM_152685
SLC23A1

solute carrier family 23 (nucleobase transporters), member 1

chr18_+_59726183 0.984 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr12_-_101396459 0.983 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chr19_-_56567602 0.973 NM_005601
NKG7
natural killer cell group 7 sequence
chr17_+_7423528 0.970 NM_001251
NM_001040059
CD68

CD68 molecule

chr14_-_23847024 0.962 CIDEB
cell death-inducing DFFA-like effector b
chr22_+_49272078 0.962 NM_017584
MIOX
myo-inositol oxygenase
chr10_-_101831579 0.953 NM_001308
CPN1
carboxypeptidase N, polypeptide 1
chr14_-_23846904 0.953 CIDEB
cell death-inducing DFFA-like effector b
chr6_+_33151703 0.941 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr14_-_23846993 0.935 CIDEB
cell death-inducing DFFA-like effector b
chr20_+_42463350 0.935 HNF4A
hepatocyte nuclear factor 4, alpha
chr22_+_20316968 0.931 NM_152612
CCDC116
coiled-coil domain containing 116
chr2_-_231498184 0.924 NM_005683
GPR55
G protein-coupled receptor 55
chr5_-_169657360 0.919 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr5_-_138746840 0.916 SLC23A1
solute carrier family 23 (nucleobase transporters), member 1
chr2_+_119905812 0.901 NM_183240
TMEM37
transmembrane protein 37
chr6_+_131190237 0.893 NM_001195597
LOC285733
hypothetical LOC285733
chr7_+_26298136 0.884 SNX10
sorting nexin 10
chr17_-_3408038 0.881 NM_145068
TRPV3
transient receptor potential cation channel, subfamily V, member 3
chr4_+_76700281 0.880 NM_178497
C4orf26
chromosome 4 open reading frame 26
chr2_+_97696462 0.877 NM_001079
ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
chr2_+_68815416 0.875 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr6_+_64289585 0.874 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr16_+_31274030 0.874 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr20_+_42463419 0.871 HNF4A
hepatocyte nuclear factor 4, alpha
chr20_+_42463387 0.868 HNF4A
hepatocyte nuclear factor 4, alpha
chr16_+_31274020 0.864 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr22_+_21393107 0.862 IGLJ3
immunoglobulin lambda joining 3
chr14_-_22658078 0.862 NM_001805
CEBPE
CCAAT/enhancer binding protein (C/EBP), epsilon
chr20_+_42463279 0.859 NM_000457
NM_178849
NM_178850
HNF4A


hepatocyte nuclear factor 4, alpha


chr4_+_6746466 0.849 NM_005980
S100P
S100 calcium binding protein P
chr16_+_65870641 0.848 PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr21_-_42659671 0.842 NM_003225
TFF1
trefoil factor 1
chr17_-_3407780 0.839 TRPV3
transient receptor potential cation channel, subfamily V, member 3
chr6_-_41781655 0.830 TFEB
transcription factor EB
chr14_+_87560646 0.828 LOC283587
hypothetical protein LOC283587
chr5_-_169657312 0.822 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr17_-_40858775 0.810 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chr17_-_31231421 0.807 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chrX_-_24600661 0.803 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr17_-_71287417 0.796 NM_005324
H3F3B
H3 histone, family 3B (H3.3B)
chr19_-_11549484 0.792 ACP5
acid phosphatase 5, tartrate resistant
chr11_+_72660894 0.783 NM_004154
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr19_-_11549441 0.777 ACP5
acid phosphatase 5, tartrate resistant
chr1_+_154351200 0.776 LMNA
lamin A/C
chr22_+_20899155 0.772


chr8_+_22266256 0.770 PIWIL2
piwi-like 2 (Drosophila)
chr8_-_82536312 0.768 NM_001080526
FABP9
fatty acid binding protein 9, testis
chr17_+_22823151 0.766 NM_014238
KSR1
kinase suppressor of ras 1
chrX_+_115481774 0.758 NM_007231
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr3_-_121884091 0.758 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr3_-_171070314 0.745 NM_024727
LRRC31
leucine rich repeat containing 31
chr17_-_77868659 0.744 NM_006137
CD7
CD7 molecule
chr16_+_65870481 0.741 NM_001129728
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr11_-_65424434 0.730 FOSL1
FOS-like antigen 1
chr19_+_1223475 0.720 CIRBP
cold inducible RNA binding protein
chr17_-_18848713 0.718 NM_001039999
FAM83G
family with sequence similarity 83, member G
chr9_-_33392505 0.716 NM_001170
AQP7
aquaporin 7
chr17_-_70480385 0.714 NM_030630
C17orf28
chromosome 17 open reading frame 28
chr13_-_59223074 0.711


chr16_+_68765428 0.710 NM_173619
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr9_-_33392583 0.708 AQP7
aquaporin 7
chr3_+_120984246 0.705 NM_022002
NR1I2
nuclear receptor subfamily 1, group I, member 2
chr10_+_49562866 0.702 WDFY4
WDFY family member 4
chr11_+_118259684 0.702 NM_001716
CXCR5
chemokine (C-X-C motif) receptor 5
chr16_-_87570716 0.699 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr11_-_65186790 0.697 RELA
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr3_-_12175646 0.697 NM_003256
TIMP4
TIMP metallopeptidase inhibitor 4
chr4_-_176970372 0.692 GPM6A
glycoprotein M6A
chr2_-_241484245 0.689 NM_001085437
C2orf54
chromosome 2 open reading frame 54
chr11_-_65424385 0.688 FOSL1
FOS-like antigen 1
chr6_+_37360144 0.688 TBC1D22B
TBC1 domain family, member 22B
chr4_-_176970407 0.684 GPM6A
glycoprotein M6A
chr1_-_152201814 0.679 SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr6_-_30236667 0.679 NM_006778
NM_052828
TRIM10

tripartite motif containing 10

chr9_-_35608300 0.676 NM_001782
CD72
CD72 molecule
chr16_+_31273969 0.671 NM_000887
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr17_+_35718948 0.668 NM_000964
RARA
retinoic acid receptor, alpha
chr12_+_54361596 0.666 NM_152637
METTL7B
methyltransferase like 7B
chr14_+_54291255 0.666 NM_001161577
SAMD4A
sterile alpha motif domain containing 4A
chr22_+_21359175 0.666 IGLV3-25
immunoglobulin lambda variable 3-25
chr12_+_119900677 0.664 HNF1A
HNF1 homeobox A
chr19_+_10820105 0.661 NM_001136482
C19orf38
chromosome 19 open reading frame 38
chr17_+_77910411 0.660 NM_207459
TEX19
testis expressed 19
chr3_-_9895633 0.657 NM_022094
CIDEC
cell death-inducing DFFA-like effector c
chr3_-_121883647 0.648 HGD
homogentisate 1,2-dioxygenase
chr19_-_11549508 0.647 NM_001611
ACP5
acid phosphatase 5, tartrate resistant
chr10_+_134751398 0.644 NM_001083909
GPR123
G protein-coupled receptor 123
chr19_+_59820413 0.636 NM_006669
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr19_-_40696393 0.634 NM_001126056
NM_001126057
NM_001126058
NM_001190347
NM_001190348
NM_001190349
NM_033317
DMKN






dermokine






chr6_+_1556543 0.634 FOXC1
forkhead box C1
chr19_-_56564068 0.633 NM_152353
CLDND2
claudin domain containing 2
chr16_+_27346079 0.631 NM_021798
IL21R
interleukin 21 receptor
chr19_-_48977247 0.630 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr16_-_30032330 0.627 NM_024307
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr19_-_53832381 0.626 NM_001352
DBP
D site of albumin promoter (albumin D-box) binding protein
chr16_+_30876115 0.624 NM_014712
SETD1A
SET domain containing 1A
chr20_+_31059174 0.623 BPIL1
bactericidal/permeability-increasing protein-like 1
chr1_-_27113018 0.622 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr1_-_45045543 0.621 NM_001013632
TCTEX1D4
Tctex1 domain containing 4
chr15_+_86983038 0.621 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr9_-_33392463 0.619 AQP7
aquaporin 7
chr8_-_68821131 0.614 NM_020361
CPA6
carboxypeptidase A6
chr1_-_120112989 0.614 NM_001166107
NM_005518
HMGCS2

3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

chr16_+_65579988 0.614 NM_173815
CES4A
carboxylesterase 4A
chr2_+_96354754 0.610 NM_001008949
NM_001163523
ITPRIPL1

inositol 1,4,5-triphosphate receptor interacting protein-like 1

chr11_-_72057755 0.607 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr17_+_7402315 0.604 NM_001198622
NM_001198623
NM_001198624
NM_003808
NM_172087
NM_172088
TNFSF13





tumor necrosis factor (ligand) superfamily, member 13





chr17_-_35331435 0.603 ORMDL3
ORM1-like 3 (S. cerevisiae)
chr20_+_41621119 0.602 SGK2
serum/glucocorticoid regulated kinase 2
chr7_+_101704145 0.599 CUX1
cut-like homeobox 1
chr19_+_40431359 0.597 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr19_-_10311262 0.593 NM_002162
ICAM3
intercellular adhesion molecule 3
chr22_+_36549334 0.593 NM_003614
GALR3
galanin receptor 3
chrX_-_76824726 0.591 ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr17_+_75319476 0.587 NM_178543
ENPP7
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr1_-_6585485 0.585 NM_014851
KLHL21
kelch-like 21 (Drosophila)
chr15_+_73803351 0.583 NM_175881
ODF3L1
outer dense fiber of sperm tails 3-like 1
chr2_-_180319013 0.581 NM_001113397
ZNF385B
zinc finger protein 385B
chr19_-_51820133 0.577 NM_000960
PTGIR
prostaglandin I2 (prostacyclin) receptor (IP)
chr12_+_54361685 0.577 METTL7B
methyltransferase like 7B
chr1_-_26070330 0.576 NM_178422
PAQR7
progestin and adipoQ receptor family member VII
chr1_-_157313179 0.573 NM_004833
AIM2
absent in melanoma 2
chr20_-_43889339 0.572 NM_003279
TNNC2
troponin C type 2 (fast)
chr9_-_86173232 0.572 NM_022127
SLC28A3
solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
chr19_+_40511909 0.572 NM_001185099
NM_001185100
NM_001185101
NM_001771
CD22



CD22 molecule



chr20_-_43972949 0.569 PLTP
phospholipid transfer protein
chr1_-_218168404 0.559


chr8_+_105421226 0.558 NM_030788
TM7SF4
transmembrane 7 superfamily member 4
chr12_-_47545816 0.551 NM_014470
RND1
Rho family GTPase 1
chr16_-_1369613 0.544 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr11_+_74548472 0.544 NM_001145211
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr3_-_122862447 0.541 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr17_-_7063625 0.540 DLG4
discs, large homolog 4 (Drosophila)
chr13_+_23742846 0.539 SPATA13
spermatogenesis associated 13
chr16_-_31068882 0.538 NM_173502
PRSS36
protease, serine, 36
chr3_-_197549640 0.538 NM_138461
TM4SF19
transmembrane 4 L six family member 19
chr11_-_117718532 0.537 NM_000732
NM_001040651
CD3D

CD3d molecule, delta (CD3-TCR complex)

chr2_+_27358800 0.536 NM_032546
NM_187841
TRIM54

tripartite motif containing 54

chr12_+_50731457 0.534 NM_002135
NM_173157
NR4A1

nuclear receptor subfamily 4, group A, member 1

chr17_-_37828643 0.534 NM_012232
PTRF
polymerase I and transcript release factor
chr12_+_63084317 0.533 NM_007235
XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr1_-_6585268 0.532 KLHL21
kelch-like 21 (Drosophila)
chr8_+_11599119 0.528 NM_002052
GATA4
GATA binding protein 4
chr16_-_4604781 0.525 FAM100A
family with sequence similarity 100, member A
chr6_+_33495824 0.524 NM_006772
SYNGAP1
synaptic Ras GTPase activating protein 1
chr16_+_28903870 0.523 NM_001014987
NM_001014988
NM_014387
LAT


linker for activation of T cells


chr4_-_71751205 0.523 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr20_-_10360569 0.522 NM_018848
MKKS
McKusick-Kaufman syndrome
chr11_+_120966280 0.521 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr17_+_71893014 0.520 SPHK1
sphingosine kinase 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.58 1.47e-04 GO:0002376 immune system process
1.20 3.75e-04 GO:0050896 response to stimulus
1.96 8.22e-04 GO:0050776 regulation of immune response
1.74 1.26e-03 GO:0002682 regulation of immune system process
1.70 1.78e-03 GO:0006955 immune response
2.68 8.94e-03 GO:0032496 response to lipopolysaccharide
1.78 2.26e-02 GO:0001775 cell activation
2.11 2.54e-02 GO:0009617 response to bacterium
1.45 4.71e-02 GO:0010033 response to organic substance

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.20 1.81e-02 GO:0005886 plasma membrane
1.85 2.67e-02 GO:0005773 vacuole
1.19 2.72e-02 GO:0071944 cell periphery
2.04 4.53e-02 GO:0030141 stored secretory granule

Nothing significant found in function category.