Motif ID: GATA1..3.p2

Z-value: 2.487


Transcription factors associated with GATA1..3.p2:

Gene SymbolEntrez IDGene Name
GATA1 2623 GATA binding protein 1 (globin transcription factor 1)
GATA2 2624 GATA binding protein 2
GATA3 2625 GATA binding protein 3



Activity profile for motif GATA1..3.p2.

activity profile for motif GATA1..3.p2


Sorted Z-values histogram for motif GATA1..3.p2

Sorted Z-values for motif GATA1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_93176819 2.249 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_30799130 2.222 TUBB
tubulin, beta
chr3_-_129023850 2.199 NM_007283
MGLL
monoglyceride lipase
chr5_+_140870881 2.141


chr7_-_81237162 2.006 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr8_-_93176618 1.878 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr5_+_140871107 1.878


chr8_-_93099040 1.859 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_-_105427898 1.834 SH3PXD2A
SH3 and PX domains 2A
chr17_-_45629401 1.796


chr9_+_112470871 1.788 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chrX_-_154216929 1.786 NM_001289
CLIC2
chloride intracellular channel 2
chrX_-_57953578 1.735 NM_007156
ZXDA
zinc finger, X-linked, duplicated A
chr18_-_51219880 1.720 TCF4
transcription factor 4
chr7_+_18501876 1.717 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr12_+_79625538 1.704 NM_002469
MYF6
myogenic factor 6 (herculin)
chr17_-_45626364 1.668


chr11_-_35503720 1.631 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr1_-_26517342 1.611 NM_145345
UBXN11
UBX domain protein 11
chr8_-_108579270 1.609 NM_001146
ANGPT1
angiopoietin 1
chr19_-_55008172 1.603 NM_001171937
NM_025129
FUZ

fuzzy homolog (Drosophila)

chrX_+_53095230 1.590 NM_018969
GPR173
G protein-coupled receptor 173
chr12_-_48902692 1.569 NM_001113547
LIMA1
LIM domain and actin binding 1
chr1_+_31654998 1.563 NM_001199038
SERINC2
serine incorporator 2
chr6_-_74284522 1.522 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr11_-_85107569 1.506 NM_206929
SYTL2
synaptotagmin-like 2
chr10_-_100985548 1.480 NM_001166244
NM_001166245
NM_001166246
NM_021828
HPSE2



heparanase 2



chr6_-_26379567 1.462 NM_003534
HIST1H3G
histone cluster 1, H3g
chr6_-_119137923 1.441 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr5_-_71838875 1.418 NM_152625
ZNF366
zinc finger protein 366
chr5_+_176494690 1.410 NSD1
nuclear receptor binding SET domain protein 1
chr4_+_134292630 1.400 PCDH10
protocadherin 10
chr13_-_32678142 1.392 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr6_+_33151703 1.365 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr11_+_5610060 1.362 NM_130390
TRIM34
tripartite motif containing 34
chr9_-_35608300 1.361 NM_001782
CD72
CD72 molecule
chr8_-_18585721 1.347 PSD3
pleckstrin and Sec7 domain containing 3
chr12_+_52733927 1.342 NM_153633
HOXC4
HOXC6
homeobox C4
homeobox C6
chr3_-_33675484 1.338 CLASP2
cytoplasmic linker associated protein 2
chr4_+_160408447 1.313 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chrX_-_135941498 1.294 NM_054021
GPR101
G protein-coupled receptor 101
chr6_-_130224108 1.280 NM_001010876
C6orf191
chromosome 6 open reading frame 191
chr21_-_35153664 1.279 RUNX1
runt-related transcription factor 1
chr1_-_226712140 1.272 NM_033445
HIST3H2A
histone cluster 3, H2a
chr8_-_93144039 1.245


chr3_-_9969057 1.238 NM_207351
PRRT3
proline-rich transmembrane protein 3
chr7_+_143263191 1.238 NM_001004685
OR2F2
olfactory receptor, family 2, subfamily F, member 2
chr12_-_48246488 1.234 NM_001012300
MCRS1
microspherule protein 1
chr20_-_56859352 1.234 GNAS-AS1
GNAS antisense RNA 1 (non-protein coding)
chr1_+_226712430 1.220 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chr2_-_144994349 1.215 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr7_+_128795178 1.194 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr3_+_179736917 1.193 NM_181361
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr16_-_87570716 1.189 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr7_+_128795280 1.146 AHCYL2
adenosylhomocysteinase-like 2
chr4_+_134293171 1.140 PCDH10
protocadherin 10
chr5_-_178977441 1.132 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr7_+_90176647 1.131 NM_012395
CDK14
cyclin-dependent kinase 14
chr8_-_93177057 1.124 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr1_+_207944807 1.122 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr8_-_93144366 1.107 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr22_+_20715340 1.102


chr1_+_170077234 1.093 NM_001136127
NM_015569
DNM3

dynamin 3

chr3_-_145049853 1.090 NM_173653
SLC9A9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr7_-_5534252 1.067 ACTB
actin, beta
chr17_-_44641741 1.055 NM_031498
NM_001198755
NM_001198756
GNGT2


guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2


chr4_+_72423633 1.054 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr3_-_11598829 1.054 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr2_-_144994038 1.038 ZEB2
zinc finger E-box binding homeobox 2
chr8_-_11096257 1.030 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr8_+_70541631 1.004 SULF1
sulfatase 1
chr3_+_142587973 0.984


chr12_-_52281050 0.980 NM_001130059
ATF7
activating transcription factor 7
chr11_-_47356479 0.978 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr6_-_76259976 0.977 NM_015687
FILIP1
filamin A interacting protein 1
chr11_-_85108030 0.977 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr10_+_18669619 0.972 NM_201590
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr15_-_78050515 0.969 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr11_-_62233552 0.965 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr4_-_138673078 0.956 NM_019035
PCDH18
protocadherin 18
chr17_+_7199178 0.954 NM_198154
TMEM95
transmembrane protein 95
chr5_-_66528330 0.943 NM_005582
CD180
CD180 molecule
chr7_+_50318801 0.930 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr1_+_81544432 0.929 LPHN2
latrophilin 2
chr6_-_32268267 0.925 GPSM3
G-protein signaling modulator 3
chr1_+_31655607 0.924 NM_001199037
SERINC2
serine incorporator 2
chr22_-_43272100 0.924 LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr15_-_75259714 0.914 PEAK1
NKF3 kinase family member
chr11_+_63730720 0.906 NM_031471
NM_178443
FERMT3

fermitin family member 3

chr13_+_49487390 0.899 NM_173605
NM_199464
TRIM13
KCNRG

tripartite motif containing 13
potassium channel regulator

chr11_-_47356562 0.897 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene spi1
chr9_+_76302071 0.894 NM_006914
RORB
RAR-related orphan receptor B
chr11_+_58146721 0.888 NM_000614
CNTF
ciliary neurotrophic factor
chr12_+_46799279 0.887 NM_000289
PFKM
phosphofructokinase, muscle
chr18_-_65766068 0.874 CD226
CD226 molecule
chr2_-_213723298 0.873 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr16_+_88305743 0.871 LOC100128881
hypothetical LOC100128881
chr14_+_95792299 0.867 NM_000710
BDKRB1
bradykinin receptor B1
chr5_+_67558217 0.867 NM_181523
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr3_+_185520744 0.862 NM_004953
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr3_+_144321286 0.862 NM_004267
CHST2
carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr2_-_29150630 0.857 NM_001029883
C2orf71
chromosome 2 open reading frame 71
chr1_+_159959072 0.855 NM_001002901
FCRLB
Fc receptor-like B
chr1_+_26516967 0.854 NM_001803
CD52
CD52 molecule
chr8_+_70567634 0.853 SULF1
sulfatase 1
chr6_+_6533932 0.852 NM_004271
LY86
lymphocyte antigen 86
chr9_+_18464138 0.850 ADAMTSL1
ADAMTS-like 1
chr1_+_200775864 0.850 NM_001197131
PPP1R12B
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr22_-_35970133 0.849 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr2_+_157822355 0.848 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chrX_-_77469635 0.847 NM_006639
CYSLTR1
cysteinyl leukotriene receptor 1
chr11_-_83071084 0.842 NM_001142702
DLG2
discs, large homolog 2 (Drosophila)
chr7_+_103756339 0.834 NM_199000
LHFPL3
lipoma HMGIC fusion partner-like 3
chr15_+_55298908 0.826 NM_207040
TCF12
transcription factor 12
chr1_-_42157077 0.822 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr12_-_15005761 0.821 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr12_+_50592379 0.815 NM_001077401
ACVRL1
activin A receptor type II-like 1
chr15_+_41597097 0.799 NM_002373
MAP1A
microtubule-associated protein 1A
chr5_-_158459276 0.797 NM_024007
EBF1
early B-cell factor 1
chr1_-_153509473 0.793 NM_003993
CLK2
CDC-like kinase 2
chr10_+_11247059 0.776 CELF2
CUGBP, Elav-like family member 2
chr8_+_70567581 0.775 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr2_-_39040981 0.774 LOC375196
hypothetical LOC375196
chr4_+_81406765 0.774 NM_004464
NM_033143
FGF5

fibroblast growth factor 5

chr1_-_42156913 0.768


chr19_-_45888259 0.765 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr1_+_152566899 0.764 NM_020452
ATP8B2
ATPase, class I, type 8B, member 2
chr15_-_59308770 0.762 NM_134261
RORA
RAR-related orphan receptor A
chr1_+_26517045 0.762 CD52
CD52 molecule
chr10_+_105334704 0.762 NEURL
neuralized homolog (Drosophila)
chr11_+_63730766 0.759 FERMT3
fermitin family member 3
chr9_+_123369219 0.757 NM_032552
DAB2IP
DAB2 interacting protein
chr4_-_138673014 0.754 PCDH18
protocadherin 18
chr11_-_57173823 0.750 NM_145008
YPEL4
yippee-like 4 (Drosophila)
chr2_+_134728299 0.745 NM_002410
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr2_-_183095308 0.742 NM_005019
NM_001003683
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr13_-_101852028 0.742 NM_175929
FGF14
fibroblast growth factor 14
chr8_-_25958291 0.739 NM_022659
EBF2
early B-cell factor 2
chr3_+_190831909 0.739 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr9_+_134026836 0.739 NTNG2
netrin G2
chr1_-_153109349 0.737 NM_002249
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr20_+_19903778 0.736 RIN2
Ras and Rab interactor 2
chr10_-_75005421 0.733 NM_152586
USP54
ubiquitin specific peptidase 54
chr8_-_17599438 0.732 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr5_-_1547872 0.731 LPCAT1
lysophosphatidylcholine acyltransferase 1
chr17_-_44642934 0.731 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr2_-_175337386 0.725 NM_000079
NM_001039523
CHRNA1

cholinergic receptor, nicotinic, alpha 1 (muscle)

chr3_-_55489973 0.723 WNT5A
wingless-type MMTV integration site family, member 5A
chr19_+_59068787 0.723 MYADM
myeloid-associated differentiation marker
chr10_+_75343352 0.720 PLAU
plasminogen activator, urokinase
chr11_+_131285747 0.717 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr10_+_70745615 0.716 NM_033496
HK1
hexokinase 1
chr17_-_35506493 0.713 NR1D1
nuclear receptor subfamily 1, group D, member 1
chr1_-_42156957 0.709 HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr1_+_154095883 0.708 NM_152280
SYT11
synaptotagmin XI
chr3_-_130761967 0.707 PLXND1
plexin D1
chr17_-_4636248 0.703 NM_001144939
NM_001144940
NM_001144941
NM_182566
VMO1



vitelline membrane outer layer 1 homolog (chicken)



chr1_+_242283129 0.699 NM_006352
ZNF238
zinc finger protein 238
chr3_-_71262426 0.698 FOXP1
forkhead box P1
chr1_+_207823667 0.696 NM_020439
CAMK1G
calcium/calmodulin-dependent protein kinase IG
chr12_+_79634820 0.696 NM_005593
MYF5
myogenic factor 5
chr1_-_144426918 0.696 NM_007053
CD160
CD160 molecule
chr5_-_139924229 0.693 NM_006051
NM_133172
NM_133173
NM_133174
APBB3



amyloid beta (A4) precursor protein-binding, family B, member 3



chr17_+_45617676 0.691


chr11_+_33520348 0.690 NM_012194
C11orf41
chromosome 11 open reading frame 41
chr10_+_70517863 0.689 SRGN
serglycin
chr17_-_39094787 0.689 NM_001040002
MEOX1
mesenchyme homeobox 1
chr18_-_50004458 0.685 MBD2
methyl-CpG binding domain protein 2
chr11_+_59979857 0.685 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr17_-_44022595 0.684 HOXB3
homeobox B3
chrX_+_78087484 0.676 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr9_-_122728173 0.674 TRAF1
TNF receptor-associated factor 1
chr14_+_99309688 0.671 EML1
echinoderm microtubule associated protein like 1
chr3_+_139211639 0.670 NM_016369
CLDN18
claudin 18
chr4_-_41848874 0.669 BEND4
BEN domain containing 4
chr15_+_39032927 0.667 NM_001142776
NM_024111
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr15_+_45797977 0.664 NM_020858
NM_024966
NM_153616
NM_153617
NM_153618
NM_153619
SEMA6D





sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D





chr3_+_185521139 0.664 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr10_+_70517823 0.664 NM_002727
SRGN
serglycin
chr9_-_16717887 0.661 BNC2
basonuclin 2
chr2_+_182558795 0.660 NM_001080545
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr9_+_18464090 0.657 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr1_-_239865724 0.657 NM_001821
CHML
choroideremia-like (Rab escort protein 2)
chr22_+_35586950 0.656 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr1_-_51660328 0.654 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr5_-_141973875 0.653 NM_033137
FGF1
fibroblast growth factor 1 (acidic)
chr1_+_50348052 0.651 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr17_+_23735637 0.647 SARM1
sterile alpha and TIR motif containing 1
chr3_+_99733432 0.646 NM_005290
GPR15
G protein-coupled receptor 15
chr1_+_242281199 0.643 ZNF238
zinc finger protein 238
chr1_+_242281175 0.640 NM_205768
ZNF238
zinc finger protein 238
chr3_-_113841448 0.637 CCDC80
coiled-coil domain containing 80
chr7_-_143560850 0.637 NM_001005287
NM_001001802
OR2A1
OR2A42
olfactory receptor, family 2, subfamily A, member 1
olfactory receptor, family 2, subfamily A, member 42
chr1_+_66570683 0.636 PDE4B
phosphodiesterase 4B, cAMP-specific
chr6_-_112147946 0.633 NM_153047
FYN
FYN oncogene related to SRC, FGR, YES
chr8_-_25958556 0.631 EBF2
early B-cell factor 2
chr11_-_58736897 0.630 NM_001039396
MPEG1
macrophage expressed 1
chr8_+_70541412 0.629 NM_001128204
NM_015170
SULF1

sulfatase 1

chr15_-_70399551 0.626 NM_052840
CELF6
CUGBP, Elav-like family member 6
chr12_+_77782719 0.626 SYT1
synaptotagmin I

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.16 1.41e-09 GO:0032501 multicellular organismal process
1.14 6.26e-09 GO:0050896 response to stimulus
1.18 3.03e-07 GO:0023052 signaling
1.21 3.32e-07 GO:0048731 system development
1.19 1.87e-06 GO:0048856 anatomical structure development
1.18 2.77e-06 GO:0007275 multicellular organismal development
1.26 4.75e-06 GO:0003008 system process
1.11 6.05e-06 GO:0050794 regulation of cellular process
1.18 8.51e-06 GO:0007165 signal transduction
1.16 3.40e-05 GO:0032502 developmental process
1.27 4.01e-05 GO:0007399 nervous system development
1.19 7.95e-05 GO:0048518 positive regulation of biological process
1.27 1.32e-04 GO:0050877 neurological system process
1.09 2.06e-04 GO:0050789 regulation of biological process
1.14 2.28e-04 GO:0051716 cellular response to stimulus
1.06 5.71e-04 GO:0009987 cellular process
1.18 7.86e-04 GO:0048522 positive regulation of cellular process
1.19 1.80e-03 GO:0048523 negative regulation of cellular process
1.08 3.83e-03 GO:0065007 biological regulation
1.18 5.17e-03 GO:0048519 negative regulation of biological process
1.40 8.35e-03 GO:0019226 transmission of nerve impulse
1.40 8.35e-03 GO:0035637 multicellular organismal signaling
1.23 9.89e-03 GO:0009966 regulation of signal transduction
1.21 1.10e-02 GO:0023051 regulation of signaling
1.31 1.34e-02 GO:0007267 cell-cell signaling
1.27 1.37e-02 GO:0007154 cell communication
1.28 1.48e-02 GO:0022008 neurogenesis
1.18 1.88e-02 GO:0048869 cellular developmental process
1.40 3.19e-02 GO:0007268 synaptic transmission
1.73 3.44e-02 GO:0042391 regulation of membrane potential
1.18 3.51e-02 GO:0048583 regulation of response to stimulus
1.32 3.69e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.18 4.44e-02 GO:0007166 cell surface receptor linked signaling pathway
1.18 4.70e-02 GO:0048513 organ development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.03 1.17e-06 GO:0005623 cell
1.03 1.51e-06 GO:0044464 cell part
1.78 6.75e-04 GO:0034703 cation channel complex
1.15 1.07e-03 GO:0043234 protein complex
1.13 1.13e-03 GO:0032991 macromolecular complex
1.05 8.00e-03 GO:0044424 intracellular part
1.06 9.49e-03 GO:0005737 cytoplasm
1.50 3.23e-02 GO:0034702 ion channel complex
1.15 4.49e-02 GO:0005829 cytosol

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 8.14e-09 GO:0005515 protein binding
1.30 1.70e-04 GO:0030528 transcription regulator activity
1.47 5.57e-03 GO:0022836 gated channel activity
2.61 1.24e-02 GO:0008066 glutamate receptor activity
1.55 1.72e-02 GO:0000975 regulatory region DNA binding
1.55 1.72e-02 GO:0001067 regulatory region nucleic acid binding
1.55 1.72e-02 GO:0044212 transcription regulatory region DNA binding
1.29 2.27e-02 GO:0043565 sequence-specific DNA binding
1.55 2.44e-02 GO:0010843 promoter binding
1.44 2.53e-02 GO:0016564 transcription repressor activity
3.05 3.85e-02 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
1.63 3.92e-02 GO:0022843 voltage-gated cation channel activity
1.54 4.23e-02 GO:0005244 voltage-gated ion channel activity
1.54 4.23e-02 GO:0022832 voltage-gated channel activity