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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: KLF4.p3

Z-value: 4.033

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr8_-_145609737	7.670		SLC39A4	solute carrier family 39 (zinc transporter), member 4
chr19_-_6718417	7.215	NM_005490	SH2D3A	SH2 domain containing 3A
chr19_-_51829778	6.734	NM_033258	GNG8	guanine nucleotide binding protein (G protein), gamma 8
chr4_-_71924409	6.311		GRSF1	G-rich RNA sequence binding factor 1
chr4_-_71924477	5.870	NM_002092	GRSF1	G-rich RNA sequence binding factor 1
chr1_+_32992131	5.596
chr7_-_150305933	5.052	NM_000238 NM_172056	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr22_-_17546296	4.387	NM_005984	SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr8_-_144887876	4.282	NM_198488	FAM83H	family with sequence similarity 83, member H
chr18_-_26935883	4.089	NM_004949 NM_024422	DSC2	desmocollin 2
chr6_-_6632197	3.980
chrX_+_15666312	3.683	NM_007220	CA5B	carbonic anhydrase VB, mitochondrial
chr11_-_65070625	3.656		LTBP3	latent transforming growth factor beta binding protein 3
chr22_-_17546276	3.632		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr16_+_87047159	3.582		ZFPM1	zinc finger protein, multitype 1
chr10_+_45189673	3.563		ALOX5	arachidonate 5-lipoxygenase
chr16_-_47873183	3.487	NM_004352	CBLN1	cerebellin 1 precursor
chr18_+_586997	3.404	NM_014410	CLUL1	clusterin-like 1 (retinal)
chr1_+_3679168	3.393	NM_001163724	LOC388588	hypothetical protein LOC388588
chr8_+_144888275	3.270		LOC100128338	hypothetical LOC100128338
chr1_-_203985752	3.229		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr11_-_2248757	3.216	NM_005170	ASCL2	achaete-scute complex homolog 2 (Drosophila)
chr1_-_1840564	3.192	NM_178545	TMEM52	transmembrane protein 52
chr1_+_30964199	3.169		LOC100129196	hypothetical LOC100129196
chr8_+_144870482	3.133	NM_139021	MAPK15	mitogen-activated protein kinase 15
chr1_-_203985780	3.126		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr22_-_17489912	3.016	NM_001173533 NM_001173534 NM_001184781 NM_005137	DGCR2	DiGeorge syndrome critical region gene 2
chr1_+_26728827	2.984	NM_002953	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr1_+_26728839	2.981		RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr22_-_17489718	2.979		DGCR2	DiGeorge syndrome critical region gene 2
chr7_+_64136078	2.957		CCT6P3	chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr1_+_26728846	2.949		RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr12_+_56435042	2.940	NM_138396	MARCH9	membrane-associated ring finger (C3HC4) 9
chr17_+_77582774	2.935	NM_005052	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr14_-_20562962	2.919	NM_201538 NM_201539 NM_201540 NM_201541	NDRG2	NDRG family member 2
chr15_-_81146188	2.911		AP3B2	adaptor-related protein complex 3, beta 2 subunit
chr11_-_64268841	2.879	NM_001098670	RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr22_+_38183480	2.831		MGAT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr22_-_17546234	2.809		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr11_+_384238	2.765		PKP3	plakophilin 3
chr1_+_158603480	2.758	NM_005598	NHLH1	nescient helix loop helix 1
chr19_-_43438818	2.754		PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr10_+_86078136	2.739	NM_018999	FAM190B	family with sequence similarity 190, member B
chr12_-_53071285	2.731	NM_001130967 NM_001130968	ZNF385A	zinc finger protein 385A
chr1_-_203985701	2.693		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr9_+_129962292	2.681	NM_024112	C9orf16	chromosome 9 open reading frame 16
chr1_-_199259133	2.669		KIF21B	kinesin family member 21B
chr22_-_17545872	2.669		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chrX_-_151688850	2.625	NM_005362	MAGEA3	melanoma antigen family A, 3
chr19_-_50975121	2.617
chr19_+_50041232	2.584	NM_001042724 NM_002856	PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr19_-_1993022	2.565		MKNK2	MAP kinase interacting serine/threonine kinase 2
chr11_+_384199	2.562	NM_007183	PKP3	plakophilin 3
chr17_-_7106987	2.496	NM_001185023 NM_001307	CLDN7	claudin 7
chr17_-_71352090	2.481		UNC13D	unc-13 homolog D (C. elegans)
chr1_-_27582368	2.451	NM_207397	CD164L2	CD164 sialomucin-like 2
chr21_+_46473494	2.428		MCM3AP-AS1	MCM3AP antisense RNA 1 (non-protein coding)
chr17_-_71352182	2.421	NM_199242	UNC13D	unc-13 homolog D (C. elegans)
chr1_-_164402575	2.421	NM_001017961	FAM78B	family with sequence similarity 78, member B
chr1_-_203985896	2.405		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr6_-_29708647	2.395		GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr15_-_70399301	2.388	NM_001172684	CELF6	CUGBP, Elav-like family member 6
chr19_+_1033797	2.382		HMHA1	histocompatibility (minor) HA-1
chr16_+_1143241	2.364	NM_001005407 NM_021098	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr1_+_224317030	2.363		H3F3A	H3 histone, family 3A
chrX_+_148671394	2.353	NM_005365 NM_001080790	MAGEA9 MAGEA9B	melanoma antigen family A, 9 melanoma antigen family A, 9B
chrX_-_100527799	2.343	NM_000061	BTK	Bruton agammaglobulinemia tyrosine kinase
chr12_-_107649383	2.342		CORO1C	coronin, actin binding protein, 1C
chr1_+_224317062	2.327		H3F3A LOC440926	H3 histone, family 3A H3 histone, family 3A pseudogene
chr20_-_55533544	2.311	NM_080618	CTCFL	CCCTC-binding factor (zinc finger protein)-like
chr19_+_7608020	2.302		STXBP2	syntaxin binding protein 2
chr12_-_56526713	2.300		CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr19_+_7608010	2.300		STXBP2	syntaxin binding protein 2
chr19_-_55763091	2.290	NM_001080457	LRRC4B	leucine rich repeat containing 4B
chr12_-_56526739	2.287		CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr8_-_144722141	2.276		C8orf73	chromosome 8 open reading frame 73
chrX_-_148476903	2.268	NM_005365 NM_001080790	MAGEA9 MAGEA9B	melanoma antigen family A, 9 melanoma antigen family A, 9B
chr19_+_50535837	2.265	NM_177417	KLC3	kinesin light chain 3
chr22_-_35113797	2.253		MYH9	myosin, heavy chain 9, non-muscle
chr3_+_47004457	2.251		NBEAL2	neurobeachin-like 2
chr19_+_7608015	2.226		STXBP2	syntaxin binding protein 2
chr12_-_56526760	2.215		CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr1_+_945331	2.210	NM_198576	AGRN	agrin
chr16_+_29582069	2.202	NM_003123	SPN	sialophorin
chr1_+_166172420	2.198	NM_001017977 NM_001198956 NM_001198957 NM_018442	DCAF6	DDB1 and CUL4 associated factor 6
chr1_+_224317056	2.197		H3F3A LOC440926	H3 histone, family 3A H3 histone, family 3A pseudogene
chr1_+_224317036	2.188	NM_002107	H3F3A	H3 histone, family 3A
chr19_+_45811316	2.180		LTBP4	latent transforming growth factor beta binding protein 4
chr7_+_73136085	2.179	NM_002314	LIMK1	LIM domain kinase 1
chr19_-_7607852	2.154
chr1_-_33588085	2.141	NM_004427	PHC2	polyhomeotic homolog 2 (Drosophila)
chr19_+_7607976	2.137	NM_001127396 NM_006949	STXBP2	syntaxin binding protein 2
chr16_-_87570716	2.120	NM_005187	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr16_-_47872973	2.119		CBLN1	cerebellin 1 precursor
chrX_-_153016337	2.116		MECP2	methyl CpG binding protein 2 (Rett syndrome)
chr17_-_23927973	2.115		ALDOC	aldolase C, fructose-bisphosphate
chrX_-_153016368	2.113	NM_001110792 NM_004992	MECP2	methyl CpG binding protein 2 (Rett syndrome)
chr22_+_21742727	2.093		GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide
chr17_-_37586716	2.088	NM_012285	KCNH4	potassium voltage-gated channel, subfamily H (eag-related), member 4
chr19_+_3129735	2.081	NM_003775	S1PR4	sphingosine-1-phosphate receptor 4
chr17_-_23928048	2.075	NM_005165	ALDOC	aldolase C, fructose-bisphosphate
chr1_-_32574185	2.072	NM_023009	MARCKSL1	MARCKS-like 1
chr19_+_34994701	2.063	NM_001238	CCNE1	cyclin E1
chr10_+_76256305	2.059	NM_012330	MYST4	MYST histone acetyltransferase (monocytic leukemia) 4
chrX_+_153318452	2.058	NM_001493	GDI1	GDP dissociation inhibitor 1
chr19_+_1033816	2.047		HMHA1	histocompatibility (minor) HA-1
chr19_-_55524445	2.047	NM_004977	KCNC3	potassium voltage-gated channel, Shaw-related subfamily, member 3
chr1_-_208046011	2.043	NM_006147	IRF6	interferon regulatory factor 6
chr1_-_203985932	2.037
chr19_-_48977247	2.023	NM_002250	KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr1_-_199259447	2.022	NM_017596	KIF21B	kinesin family member 21B
chr16_+_29725597	2.021
chr20_-_538909	2.021	NM_004609	TCF15	transcription factor 15 (basic helix-loop-helix)
chr22_-_20551937	2.020		MAPK1	mitogen-activated protein kinase 1
chr1_+_199259664	2.020
chr1_+_28458546	2.017	NM_031459	SESN2	sestrin 2
chr1_+_41022066	2.017	NM_004700 NM_172163	KCNQ4	potassium voltage-gated channel, KQT-like subfamily, member 4
chr15_-_70399181	2.016		CELF6	CUGBP, Elav-like family member 6
chr3_-_187025501	2.014	NM_001007225 NM_006548	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr7_-_3049872	2.010	NM_032415	CARD11	caspase recruitment domain family, member 11
chr1_+_224317044	2.010		H3F3A LOC440926	H3 histone, family 3A H3 histone, family 3A pseudogene
chr10_+_75427853	2.009	NM_003373 NM_014000	VCL	vinculin
chr17_-_23928041	2.002		ALDOC	aldolase C, fructose-bisphosphate
chr12_-_56527013	1.994	NM_005730	CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr19_-_43608641	1.988	NM_001146202 NM_001146203 NM_001146204 NM_001146205 NM_001146206 NM_001146207 NM_170604	RASGRP4	RAS guanyl releasing protein 4
chr15_+_78232160	1.986		FAH	fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr12_-_32940931	1.983	NM_001005242 NM_004572	PKP2	plakophilin 2
chr19_-_60587414	1.975	NM_001190764	LOC388564	hypothetical protein LOC388564
chrX_+_64804318	1.973		MSN	moesin
chr22_-_20551953	1.969	NM_002745 NM_138957	MAPK1	mitogen-activated protein kinase 1
chrX_-_152643016	1.968	NM_005745	BCAP31	B-cell receptor-associated protein 31
chr1_-_221383212	1.967	NM_003268	TLR5	toll-like receptor 5
chr20_+_61654816	1.958	NM_024059	C20orf195	chromosome 20 open reading frame 195
chr6_+_34312906	1.948		HMGA1	high mobility group AT-hook 1
chrX_-_135161185	1.948	NM_001173517 NM_024597	MAP7D3	MAP7 domain containing 3
chr17_-_71352017	1.945		UNC13D	unc-13 homolog D (C. elegans)
chr16_+_29725665	1.942
chr17_+_7495140	1.941		ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide
chr16_+_29581783	1.940	NM_001030288	SPN	sialophorin
chr7_+_128257698	1.940	NM_001127487 NM_001458	FLNC	filamin C, gamma
chr16_+_29725311	1.922	NM_001042539 NM_002383	MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chrX_-_152643001	1.918
chrX_+_64804235	1.906	NM_002444	MSN	moesin
chr5_+_137701852	1.903		FAM53C	family with sequence similarity 53, member C
chr1_-_33587998	1.900		PHC2	polyhomeotic homolog 2 (Drosophila)
chrX_+_9392980	1.899	NM_005647	TBL1X	transducin (beta)-like 1X-linked
chr1_+_12149637	1.890	NM_001066	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B
chr11_-_63770716	1.889		PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr1_+_984935	1.889		LOC100288175	hypothetical LOC100288175
chr22_+_20316968	1.877	NM_152612	CCDC116	coiled-coil domain containing 116
chr17_-_73867748	1.875	NM_003955	SOCS3	suppressor of cytokine signaling 3
chr19_-_18493886	1.872	NM_006532	ELL	elongation factor RNA polymerase II
chr22_+_21742364	1.869	NM_002073	GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide
chr21_+_29593098	1.855		BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chrX_-_153016173	1.850		MECP2 LOC728653	methyl CpG binding protein 2 (Rett syndrome) hypothetical protein LOC728653
chrX_+_118592568	1.848		UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)
chr19_+_12805747	1.834		MAST1	microtubule associated serine/threonine kinase 1
chr1_-_203985963	1.829	NM_022731	NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr19_-_6453224	1.824	NM_006087	TUBB4	tubulin, beta 4
chr1_+_24944554	1.818		CLIC4	chloride intracellular channel 4
chr11_+_46256161	1.815		CREB3L1	cAMP responsive element binding protein 3-like 1
chr22_-_35113876	1.813		MYH9	myosin, heavy chain 9, non-muscle
chr19_+_60283571	1.809	NM_017729	EPS8L1	EPS8-like 1
chr9_+_138760432	1.807		LOC100128593	hypothetical LOC100128593
chr19_+_10392128	1.806	NM_001111307	PDE4A	phosphodiesterase 4A, cAMP-specific
chr19_-_1062972	1.803		SBNO2	strawberry notch homolog 2 (Drosophila)
chr8_-_145671947	1.798		FOXH1	forkhead box H1
chr19_+_18069596	1.794	NM_015016	MAST3	microtubule associated serine/threonine kinase 3
chr19_-_43439011	1.790	NM_033256	PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr18_+_9904202	1.789		VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr6_+_44203335	1.785	NM_018426	TMEM63B	transmembrane protein 63B
chr15_+_78232184	1.783		FAH	fumarylacetoacetate hydrolase (fumarylacetoacetase)
chrX_+_64804259	1.781		MSN	moesin
chr10_-_134940315	1.781	NM_001109 NM_001164489 NM_001164490	ADAM8	ADAM metallopeptidase domain 8
chrX_-_20195062	1.780		RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr19_+_10843244	1.779	NM_199141	CARM1	coactivator-associated arginine methyltransferase 1
chr6_-_31806012	1.778	NM_013974	DDAH2	dimethylarginine dimethylaminohydrolase 2
chr1_+_6767968	1.778	NM_001195563 NM_015215	CAMTA1	calmodulin binding transcription activator 1
chr5_+_177473071	1.778	NM_015111	N4BP3	NEDD4 binding protein 3
chr7_-_150283794	1.776	NM_172057	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr11_+_46256130	1.772		CREB3L1	cAMP responsive element binding protein 3-like 1
chr16_+_23754772	1.769	NM_002738 NM_212535	PRKCB	protein kinase C, beta
chr8_-_145136125	1.762		PARP10	poly (ADP-ribose) polymerase family, member 10
chr1_+_38046404	1.760		C1orf122	chromosome 1 open reading frame 122
chrX_-_153252775	1.758		FLNA	filamin A, alpha
chr12_-_107649418	1.757	NM_014325	CORO1C	coronin, actin binding protein, 1C
chr1_-_164402700	1.749		FAM78B	family with sequence similarity 78, member B
chr1_+_24944493	1.749		CLIC4	chloride intracellular channel 4
chr19_-_48976852	1.746		KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr11_-_2248374	1.746		ASCL2	achaete-scute complex homolog 2 (Drosophila)
chr12_-_107649404	1.744		CORO1C	coronin, actin binding protein, 1C
chr9_-_138701644	1.741		AGPAT2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr6_-_31805932	1.741		DDAH2	dimethylarginine dimethylaminohydrolase 2
chr17_-_53764867	1.735
chr12_-_6586811	1.731	NM_001273	CHD4	chromodomain helicase DNA binding protein 4
chr22_+_38183262	1.731	NM_002409	MGAT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr19_-_3737382	1.726	NM_139354 NM_139355	MATK	megakaryocyte-associated tyrosine kinase
chr16_+_23754822	1.718		PRKCB	protein kinase C, beta
chr22_-_22511173	1.715	NM_001002862 NM_001135751 NM_198440	DERL3	Der1-like domain family, member 3
chr20_+_61841662	1.714		SLC2A4RG	SLC2A4 regulator

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.08	2.12e-29	GO:0009987	cellular process
1.14	8.12e-24	GO:0044237	cellular metabolic process
1.16	1.33e-18	GO:0044260	cellular macromolecule metabolic process
1.12	3.20e-18	GO:0044238	primary metabolic process
1.11	8.32e-18	GO:0008152	metabolic process
1.10	1.27e-14	GO:0050789	regulation of biological process
1.10	4.94e-14	GO:0050794	regulation of cellular process
1.13	1.82e-13	GO:0043170	macromolecule metabolic process
1.09	1.55e-12	GO:0065007	biological regulation
1.22	1.31e-11	GO:0006464	protein modification process
1.18	2.39e-11	GO:0044267	cellular protein metabolic process
1.15	2.01e-10	GO:0016043	cellular component organization
1.14	4.68e-10	GO:0031323	regulation of cellular metabolic process
1.20	5.29e-10	GO:0043412	macromolecule modification
1.22	7.63e-10	GO:0023051	regulation of signaling
1.14	2.20e-09	GO:0080090	regulation of primary metabolic process
1.21	3.08e-09	GO:0006996	organelle organization
1.18	3.33e-09	GO:0048523	negative regulation of cellular process
1.17	4.69e-09	GO:0048519	negative regulation of biological process
1.14	5.00e-09	GO:0071840	cellular component organization or biogenesis
1.15	1.28e-08	GO:0048518	positive regulation of biological process
1.16	1.41e-08	GO:0071842	cellular component organization at cellular level
1.12	1.89e-08	GO:0019222	regulation of metabolic process
1.16	8.95e-08	GO:0048522	positive regulation of cellular process
1.13	1.73e-07	GO:0006807	nitrogen compound metabolic process
1.15	1.77e-07	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.13	2.09e-07	GO:0034641	cellular nitrogen compound metabolic process
1.21	2.37e-07	GO:0009966	regulation of signal transduction
1.25	2.48e-07	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.14	4.20e-07	GO:0071841	cellular component organization or biogenesis at cellular level
1.13	6.05e-07	GO:0019538	protein metabolic process
1.15	1.27e-06	GO:0009058	biosynthetic process
1.14	1.40e-06	GO:0051171	regulation of nitrogen compound metabolic process
1.12	1.81e-06	GO:0060255	regulation of macromolecule metabolic process
1.15	2.41e-06	GO:0044249	cellular biosynthetic process
1.14	4.45e-06	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25	5.70e-06	GO:0008219	cell death
1.25	8.52e-06	GO:0016265	death
1.14	2.11e-05	GO:0051252	regulation of RNA metabolic process
1.18	2.12e-05	GO:0009056	catabolic process
1.13	7.61e-05	GO:0010468	regulation of gene expression
1.10	8.26e-05	GO:0032502	developmental process
1.19	1.02e-04	GO:0009893	positive regulation of metabolic process
1.20	1.21e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.26	1.47e-04	GO:0010628	positive regulation of gene expression
1.14	1.62e-04	GO:0090304	nucleic acid metabolic process
1.20	1.74e-04	GO:0043067	regulation of programmed cell death
1.10	1.80e-04	GO:0023052	signaling
1.20	1.93e-04	GO:0042981	regulation of apoptosis
1.14	2.32e-04	GO:0006355	regulation of transcription, DNA-dependent
1.18	2.36e-04	GO:0033036	macromolecule localization
1.18	2.50e-04	GO:0035556	intracellular signal transduction
1.20	2.50e-04	GO:0010941	regulation of cell death
1.09	2.68e-04	GO:0051716	cellular response to stimulus
1.13	3.12e-04	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.36	3.42e-04	GO:0070647	protein modification by small protein conjugation or removal
1.19	4.04e-04	GO:0044248	cellular catabolic process
1.20	4.37e-04	GO:0007049	cell cycle
1.22	4.44e-04	GO:0051128	regulation of cellular component organization
1.20	5.19e-04	GO:0010646	regulation of cell communication
1.20	5.51e-04	GO:0006793	phosphorus metabolic process
1.20	5.51e-04	GO:0006796	phosphate metabolic process
1.18	5.57e-04	GO:0031325	positive regulation of cellular metabolic process
1.25	6.14e-04	GO:0051254	positive regulation of RNA metabolic process
1.15	6.49e-04	GO:0034645	cellular macromolecule biosynthetic process
1.16	6.70e-04	GO:0007399	nervous system development
1.12	7.31e-04	GO:0031326	regulation of cellular biosynthetic process
1.20	7.89e-04	GO:0032879	regulation of localization
1.14	8.82e-04	GO:0048583	regulation of response to stimulus
1.15	9.10e-04	GO:0009059	macromolecule biosynthetic process
1.28	1.00e-03	GO:0051338	regulation of transferase activity
1.33	1.08e-03	GO:0030163	protein catabolic process
1.22	1.08e-03	GO:0031399	regulation of protein modification process
1.10	1.10e-03	GO:0051179	localization
1.10	1.10e-03	GO:0007165	signal transduction
1.24	1.12e-03	GO:0019220	regulation of phosphate metabolic process
1.24	1.12e-03	GO:0051174	regulation of phosphorus metabolic process
1.25	1.20e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.25	1.20e-03	GO:0051276	chromosome organization
1.25	1.42e-03	GO:0051726	regulation of cell cycle
1.19	1.63e-03	GO:0051246	regulation of protein metabolic process
1.10	1.64e-03	GO:0048856	anatomical structure development
1.22	2.06e-03	GO:0006468	protein phosphorylation
1.24	2.11e-03	GO:0042325	regulation of phosphorylation
1.21	2.24e-03	GO:0016310	phosphorylation
1.11	2.33e-03	GO:0009889	regulation of biosynthetic process
1.20	2.54e-03	GO:0006351	transcription, DNA-dependent
1.18	2.54e-03	GO:0008104	protein localization
1.31	2.94e-03	GO:0007264	small GTPase mediated signal transduction
1.27	3.10e-03	GO:0043549	regulation of kinase activity
1.24	3.82e-03	GO:0009057	macromolecule catabolic process
1.33	3.87e-03	GO:0051603	proteolysis involved in cellular protein catabolic process
1.14	3.96e-03	GO:0016070	RNA metabolic process
1.33	3.97e-03	GO:0043632	modification-dependent macromolecule catabolic process
1.33	4.00e-03	GO:0019941	modification-dependent protein catabolic process
1.33	4.09e-03	GO:0006511	ubiquitin-dependent protein catabolic process
1.11	4.32e-03	GO:0010556	regulation of macromolecule biosynthetic process
1.26	4.48e-03	GO:0044265	cellular macromolecule catabolic process
1.23	4.65e-03	GO:0045595	regulation of cell differentiation
1.26	4.76e-03	GO:0070727	cellular macromolecule localization
1.18	4.87e-03	GO:0032268	regulation of cellular protein metabolic process
1.21	4.99e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.19	5.04e-03	GO:0050793	regulation of developmental process
1.24	5.87e-03	GO:0051172	negative regulation of nitrogen compound metabolic process
1.19	5.88e-03	GO:0031324	negative regulation of cellular metabolic process
1.27	5.96e-03	GO:0045859	regulation of protein kinase activity
1.09	6.11e-03	GO:0007275	multicellular organismal development
1.26	6.19e-03	GO:0034613	cellular protein localization
1.19	6.48e-03	GO:0048468	cell development
1.32	6.66e-03	GO:0044257	cellular protein catabolic process
1.32	7.08e-03	GO:0051347	positive regulation of transferase activity
1.19	7.37e-03	GO:0010605	negative regulation of macromolecule metabolic process
1.20	7.79e-03	GO:0045184	establishment of protein localization
1.23	7.86e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.13	8.40e-03	GO:0010467	gene expression
1.28	8.56e-03	GO:0008285	negative regulation of cell proliferation
1.18	9.54e-03	GO:0042127	regulation of cell proliferation
1.15	9.59e-03	GO:0065009	regulation of molecular function
1.25	9.76e-03	GO:0051253	negative regulation of RNA metabolic process
1.32	9.84e-03	GO:0033674	positive regulation of kinase activity
1.18	1.00e-02	GO:0032774	RNA biosynthetic process
1.25	1.09e-02	GO:0045892	negative regulation of transcription, DNA-dependent
1.19	1.33e-02	GO:0015031	protein transport
1.63	1.41e-02	GO:0030522	intracellular receptor mediated signaling pathway
1.18	1.44e-02	GO:0009892	negative regulation of metabolic process
1.39	1.52e-02	GO:0001701	in utero embryonic development
1.10	1.59e-02	GO:0051234	establishment of localization
1.23	1.60e-02	GO:0010629	negative regulation of gene expression
1.20	1.66e-02	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22	1.73e-02	GO:0001932	regulation of protein phosphorylation
1.32	1.83e-02	GO:0045860	positive regulation of protein kinase activity
1.28	1.83e-02	GO:0010627	regulation of intracellular protein kinase cascade
1.24	1.85e-02	GO:0010942	positive regulation of cell death
1.68	1.87e-02	GO:0030518	steroid hormone receptor signaling pathway
1.10	1.89e-02	GO:0006810	transport
1.22	1.95e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.25	2.02e-02	GO:0043068	positive regulation of programmed cell death
1.29	2.12e-02	GO:0016568	chromatin modification
1.21	2.19e-02	GO:0006915	apoptosis
1.36	2.21e-02	GO:0051129	negative regulation of cellular component organization
1.15	2.32e-02	GO:0051239	regulation of multicellular organismal process
1.62	2.33e-02	GO:0000209	protein polyubiquitination
1.10	2.34e-02	GO:0048731	system development
1.28	2.63e-02	GO:0009792	embryo development ending in birth or egg hatching
1.33	2.69e-02	GO:0032446	protein modification by small protein conjugation
1.20	2.80e-02	GO:0012501	programmed cell death
1.34	2.88e-02	GO:0016567	protein ubiquitination
1.25	2.91e-02	GO:0006325	chromatin organization
1.24	3.12e-02	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.21	3.85e-02	GO:0007167	enzyme linked receptor protein signaling pathway
1.24	4.00e-02	GO:0043065	positive regulation of apoptosis
1.20	4.00e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
1.28	4.49e-02	GO:0043009	chordate embryonic development
1.19	4.49e-02	GO:2000026	regulation of multicellular organismal development
1.27	4.64e-02	GO:0006886	intracellular protein transport

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.11	4.52e-61	GO:0044424	intracellular part
1.11	6.89e-58	GO:0005622	intracellular
1.12	4.61e-44	GO:0043226	organelle
1.12	8.23e-44	GO:0043229	intracellular organelle
1.14	3.23e-42	GO:0005737	cytoplasm
1.13	1.26e-41	GO:0043231	intracellular membrane-bounded organelle
1.13	1.81e-41	GO:0043227	membrane-bounded organelle
1.15	1.27e-26	GO:0005634	nucleus
1.14	7.30e-24	GO:0044444	cytoplasmic part
1.14	3.55e-23	GO:0044446	intracellular organelle part
1.14	3.10e-22	GO:0044422	organelle part
1.22	4.60e-15	GO:0005829	cytosol
1.20	1.84e-12	GO:0044428	nuclear part
1.03	5.77e-12	GO:0044464	cell part
1.03	6.65e-12	GO:0005623	cell
1.20	1.96e-10	GO:0031981	nuclear lumen
1.17	2.09e-10	GO:0031974	membrane-enclosed lumen
1.18	2.77e-10	GO:0070013	intracellular organelle lumen
1.17	4.14e-10	GO:0043233	organelle lumen
1.22	9.54e-09	GO:0005654	nucleoplasm
1.29	1.09e-07	GO:0015630	microtubule cytoskeleton
1.19	1.23e-07	GO:0012505	endomembrane system
1.13	2.33e-07	GO:0043234	protein complex
1.13	4.46e-07	GO:0043228	non-membrane-bounded organelle
1.13	4.46e-07	GO:0043232	intracellular non-membrane-bounded organelle
1.11	6.29e-06	GO:0032991	macromolecular complex
1.13	1.20e-04	GO:0031090	organelle membrane
1.21	3.29e-04	GO:0031982	vesicle
1.18	7.35e-04	GO:0005794	Golgi apparatus
1.20	9.47e-04	GO:0031410	cytoplasmic vesicle
1.24	1.18e-03	GO:0005694	chromosome
1.21	1.38e-03	GO:0031988	membrane-bounded vesicle
1.14	1.39e-03	GO:0005856	cytoskeleton
1.20	2.83e-03	GO:0016023	cytoplasmic membrane-bounded vesicle
1.40	4.03e-03	GO:0030424	axon
1.24	5.84e-03	GO:0044427	chromosomal part
1.30	7.83e-03	GO:0005874	microtubule
1.16	8.41e-03	GO:0044430	cytoskeletal part
1.26	8.73e-03	GO:0043005	neuron projection
1.19	1.02e-02	GO:0044451	nucleoplasm part
1.27	1.03e-02	GO:0048471	perinuclear region of cytoplasm
1.16	2.35e-02	GO:0042995	cell projection
1.51	2.86e-02	GO:0042470	melanosome
1.51	2.86e-02	GO:0048770	pigment granule
1.20	3.54e-02	GO:0044431	Golgi apparatus part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.16	1.56e-43	GO:0005515	protein binding
1.08	3.49e-31	GO:0005488	binding
1.19	8.47e-13	GO:0000166	nucleotide binding
1.42	3.99e-09	GO:0000988	protein binding transcription factor activity
1.42	3.99e-09	GO:0000989	transcription factor binding transcription factor activity
1.42	5.75e-09	GO:0003712	transcription cofactor activity
1.18	9.09e-09	GO:0017076	purine nucleotide binding
1.18	1.05e-08	GO:0032553	ribonucleotide binding
1.18	1.05e-08	GO:0032555	purine ribonucleotide binding
1.18	2.66e-08	GO:0035639	purine ribonucleoside triphosphate binding
1.28	1.65e-07	GO:0019899	enzyme binding
1.18	5.69e-07	GO:0030554	adenyl nucleotide binding
1.18	8.98e-07	GO:0032559	adenyl ribonucleotide binding
1.26	2.13e-06	GO:0016301	kinase activity
1.18	2.40e-06	GO:0005524	ATP binding
1.08	5.84e-06	GO:0003824	catalytic activity
1.23	1.13e-05	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.21	1.16e-05	GO:0030528	transcription regulator activity
1.32	1.18e-05	GO:0019904	protein domain specific binding
1.16	1.32e-05	GO:0016740	transferase activity
1.39	1.34e-05	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.45	2.14e-05	GO:0003713	transcription coactivator activity
1.40	3.30e-05	GO:0016881	acid-amino acid ligase activity
1.24	8.57e-05	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.22	4.09e-04	GO:0042802	identical protein binding
1.37	1.78e-03	GO:0019787	small conjugating protein ligase activity
1.27	1.95e-03	GO:0004674	protein serine/threonine kinase activity
1.31	2.62e-03	GO:0016563	transcription activator activity
1.11	3.23e-03	GO:0003677	DNA binding
1.09	4.30e-03	GO:0003676	nucleic acid binding
1.37	4.68e-03	GO:0004842	ubiquitin-protein ligase activity
1.31	4.85e-03	GO:0016564	transcription repressor activity
1.25	7.82e-03	GO:0016874	ligase activity
1.25	9.46e-03	GO:0030695	GTPase regulator activity
1.21	1.27e-02	GO:0004672	protein kinase activity
1.47	1.89e-02	GO:0051020	GTPase binding
1.23	1.97e-02	GO:0060589	nucleoside-triphosphatase regulator activity
1.30	2.01e-02	GO:0008134	transcription factor binding
1.47	2.81e-02	GO:0015631	tubulin binding
1.16	3.68e-02	GO:0001071	nucleic acid binding transcription factor activity
1.16	3.68e-02	GO:0003700	sequence-specific DNA binding transcription factor activity