Motif ID: MAFB.p2

Z-value: 3.450


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)



Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_50004458 2.758 MBD2
methyl-CpG binding domain protein 2
chr4_+_61749540 2.709 LPHN3
latrophilin 3
chrX_-_83329562 2.580 NM_014496
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr3_-_62835601 2.547


chrX_+_51503219 2.424 NM_018094
GSPT2
G1 to S phase transition 2
chr2_-_192767494 2.341 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr11_-_35503720 2.313 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr5_+_140326237 2.263 PCDHAC2
protocadherin alpha subfamily C, 2
chr3_+_148610516 2.240 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr3_-_69674412 2.232 FRMD4B
FERM domain containing 4B
chr9_-_25668230 2.212 TUSC1
tumor suppressor candidate 1
chr4_-_111763655 2.094 NM_000325
PITX2
paired-like homeodomain 2
chr1_+_66772393 2.083 NM_032291
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr3_-_64186151 2.057 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr7_+_7188667 2.054 NM_020156
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr8_-_108579270 2.051 NM_001146
ANGPT1
angiopoietin 1
chr12_+_52618815 2.043 NM_017410
HOXC13
homeobox C13
chr17_+_36515166 2.024 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr20_+_52525538 2.008 NM_018431
DOK5
docking protein 5
chr17_+_31975611 1.986 GGNBP2
gametogenetin binding protein 2
chr9_-_84867604 1.967 RASEF
RAS and EF-hand domain containing
chr17_-_28644118 1.934 NM_183377
ACCN1
amiloride-sensitive cation channel 1, neuronal
chr2_+_104838177 1.934 NM_006236
POU3F3
POU class 3 homeobox 3
chr20_+_19903778 1.927 RIN2
Ras and Rab interactor 2
chr6_-_85530617 1.914 NM_001080508
TBX18
T-box 18
chr10_-_17536181 1.908 NM_001004470
ST8SIA6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr9_+_129893948 1.888 NM_001006642
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr16_+_81218142 1.877 CDH13
cadherin 13, H-cadherin (heart)
chr16_+_81218074 1.857 NM_001257
CDH13
cadherin 13, H-cadherin (heart)
chr15_+_31390454 1.855 NM_001036
RYR3
ryanodine receptor 3
chr19_-_9982041 1.839 NM_015719
COL5A3
collagen, type V, alpha 3
chr15_+_90738108 1.782 NM_006011
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr8_-_66916197 1.758 NM_002604
PDE7A
phosphodiesterase 7A
chr14_+_85066265 1.748 FLRT2
fibronectin leucine rich transmembrane protein 2
chrX_-_34585287 1.728 NM_031442
TMEM47
transmembrane protein 47
chr14_+_28305922 1.722 NM_005249
FOXG1
forkhead box G1
chr15_-_81037554 1.719 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr4_-_111763356 1.715 PITX2
paired-like homeodomain 2
chr7_-_41709191 1.701 NM_002192
INHBA
inhibin, beta A
chr5_-_146238336 1.698 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr12_-_68369322 1.694 NM_152439
BEST3
bestrophin 3
chr9_+_134447795 1.685 NM_020064
BARHL1
BarH-like homeobox 1
chr5_-_59225377 1.675 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_-_78229838 1.670 NM_000863
HTR1B
5-hydroxytryptamine (serotonin) receptor 1B
chr8_+_24827181 1.662 NEFM
neurofilament, medium polypeptide
chr14_+_85066207 1.654 NM_013231
FLRT2
fibronectin leucine rich transmembrane protein 2
chr11_-_129803515 1.648 ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr8_+_24827173 1.600 NM_005382
NEFM
neurofilament, medium polypeptide
chr2_+_26768894 1.600 NM_002246
KCNK3
potassium channel, subfamily K, member 3
chr7_-_127458231 1.596 NM_022143
LRRC4
leucine rich repeat containing 4
chr1_+_199884152 1.585 NAV1
neuron navigator 1
chr8_+_31616809 1.573 NM_013962
NRG1
neuregulin 1
chr3_-_185025989 1.573 NM_024871
MAP6D1
MAP6 domain containing 1
chr5_-_168660293 1.571 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr9_+_35528890 1.570 RUSC2
RUN and SH3 domain containing 2
chr5_+_66160359 1.546 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr1_-_51198383 1.539 FAF1
Fas (TNFRSF6) associated factor 1
chr20_-_22978141 1.538 NM_000361
THBD
thrombomodulin
chr1_+_175407153 1.527 NM_021165
FAM5B
family with sequence similarity 5, member B
chr17_-_47590669 1.522 CA10
carbonic anhydrase X
chr22_+_28206180 1.499 NM_021076
NEFH
neurofilament, heavy polypeptide
chr18_+_9092618 1.496 NM_021074
NDUFV2
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr15_-_32875040 1.492 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr9_-_16717887 1.479 BNC2
basonuclin 2
chr17_-_36475652 1.476 NM_033184
KRTAP2-4
keratin associated protein 2-4
chr17_+_36493927 1.466 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr3_+_49002774 1.455 P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr18_+_9092688 1.445 NDUFV2
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr8_+_1936549 1.442 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr19_-_13478037 1.437 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr9_-_79835970 1.415 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr4_+_134289893 1.410 NM_020815
NM_032961
PCDH10

protocadherin 10

chr11_-_88864061 1.403 NM_001143836
NM_016931
NOX4

NADPH oxidase 4

chr19_-_45888259 1.393 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr22_-_34566276 1.393 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr8_-_89408832 1.386 NM_005941
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr5_-_146869613 1.372 DPYSL3
dihydropyrimidinase-like 3
chr11_+_131285747 1.353 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr1_-_51198328 1.352 FAF1
Fas (TNFRSF6) associated factor 1
chr17_-_36528113 1.350 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr10_+_52504239 1.348 NM_006258
PRKG1
protein kinase, cGMP-dependent, type I
chr5_-_146869811 1.347 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chrX_-_43717864 1.339 NM_000266
NDP
Norrie disease (pseudoglioma)
chr10_-_17536351 1.339 ST8SIA6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr8_-_57286381 1.337 PLAG1
pleiomorphic adenoma gene 1
chr2_+_188864848 1.332 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr9_-_84867862 1.325 NM_152573
RASEF
RAS and EF-hand domain containing
chr8_+_32525269 1.314 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr12_+_61147083 1.294 MON2
MON2 homolog (S. cerevisiae)
chr2_+_71534260 1.293 NM_001130976
NM_001130977
NM_001130978
NM_001130979
NM_001130980
NM_001130981
NM_003494
DYSF






dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)






chr4_+_160408447 1.290 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr17_-_44058612 1.289 NM_024017
HOXB9
homeobox B9
chr7_-_27190882 1.286 HOXA11
homeobox A11
chr6_-_76051216 1.286 TMEM30A
transmembrane protein 30A
chr12_+_52665196 1.285 NM_017409
HOXC10
homeobox C10
chr1_-_51198417 1.281 FAF1
Fas (TNFRSF6) associated factor 1
chr22_-_34566367 1.280 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr8_-_57286412 1.276 NM_001114634
NM_001114635
NM_002655
PLAG1


pleiomorphic adenoma gene 1


chr2_-_206659140 1.272 NM_017759
INO80D
INO80 complex subunit D
chr20_+_32610161 1.265 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr2_+_188864898 1.263 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr18_-_33399601 1.252 CELF4
CUGBP, Elav-like family member 4
chr5_+_72179685 1.251 NM_153188
TNPO1
transportin 1
chr16_+_1524162 1.250 NM_024600
TMEM204
transmembrane protein 204
chr13_-_107317460 1.245 NM_001080396
FAM155A
family with sequence similarity 155, member A
chr15_-_37999519 1.244


chr9_-_112381593 1.242 NM_153366
SVEP1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr11_-_76800525 1.234 PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr8_+_99508425 1.222 NM_020697
KCNS2
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
chr1_-_243094404 1.219 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr2_+_176695658 1.217 NM_014213
HOXD9
homeobox D9
chr1_-_43005312 1.212 NM_001146289
NM_022356
LEPRE1

leucine proline-enriched proteoglycan (leprecan) 1

chr2_-_39201066 1.212 NM_005633
SOS1
son of sevenless homolog 1 (Drosophila)
chr4_+_174528602 1.208 NM_003864
SAP30
Sin3A-associated protein, 30kDa
chr5_+_140848905 1.203 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr5_+_174084137 1.199 NM_002449
MSX2
msh homeobox 2
chr1_-_51198506 1.197 NM_007051
FAF1
Fas (TNFRSF6) associated factor 1
chr22_-_34566210 1.196 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_+_183970093 1.191 NM_031935
HMCN1
hemicentin 1
chr6_+_150505849 1.190 NM_030949
PPP1R14C
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chrX_+_37315740 1.189 NM_001170331
NM_198511
LANCL3

LanC lantibiotic synthetase component C-like 3 (bacterial)

chr18_-_24010944 1.188 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr7_-_35260213 1.184 NM_001077653
NM_001166220
TBX20

T-box 20

chr7_-_105011055 1.175 YBX1P2
Y box binding protein 1 pseudogene 2
chr2_+_188865634 1.173 NM_016315
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr2_+_188865796 1.172 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr10_-_79067210 1.167 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr2_-_153282104 1.165 NM_017892
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr13_-_25523164 1.165 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chrX_+_103297891 1.163 NM_207318
FAM199X
family with sequence similarity 199, X-linked
chr15_+_45796802 1.160 SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr7_-_32076985 1.159 NM_001191056
NM_001191057
PDE1C

phosphodiesterase 1C, calmodulin-dependent 70kDa

chr12_+_50587468 1.153 NM_000020
ACVRL1
activin A receptor type II-like 1
chr8_+_64243662 1.153 NM_152758
YTHDF3
YTH domain family, member 3
chr4_+_153676857 1.146 DKFZP434I0714
hypothetical protein DKFZP434I0714
chr3_-_88190737 1.144 NM_001008390
NM_003663
CGGBP1

CGG triplet repeat binding protein 1

chr9_-_85512311 1.143 UBQLN1
ubiquilin 1
chr15_+_41597097 1.142 NM_002373
MAP1A
microtubule-associated protein 1A
chr15_+_45263517 1.137 NM_001198999
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr6_-_84197573 1.134 NM_002395
ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr9_-_135232639 1.131 SURF4
surfeit 4
chr5_+_159276317 1.126 NM_000679
ADRA1B
adrenergic, alpha-1B-, receptor
chr10_+_72102563 1.124 NM_080722
NM_139155
ADAMTS14

ADAM metallopeptidase with thrombospondin type 1 motif, 14

chr6_-_76051159 1.123 TMEM30A
transmembrane protein 30A
chr4_+_174528675 1.120 SAP30
Sin3A-associated protein, 30kDa
chr1_-_43005243 1.120 LEPRE1
leucine proline-enriched proteoglycan (leprecan) 1
chr8_+_64243741 1.110 YTHDF3
YTH domain family, member 3
chr8_+_106400322 1.104 NM_012082
ZFPM2
zinc finger protein, multitype 2
chr6_-_84197477 1.104 ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chrX_+_66683075 1.101 AR
androgen receptor
chr6_-_76051197 1.101 TMEM30A
transmembrane protein 30A
chr10_-_13083576 1.095 NM_031455
CCDC3
coiled-coil domain containing 3
chr3_-_188945921 1.092 BCL6
B-cell CLL/lymphoma 6
chr7_-_27120015 1.090 HOXA3
homeobox A3
chr10_+_25504295 1.087 NM_020752
GPR158
G protein-coupled receptor 158
chr17_+_7883076 1.084 NM_001039130
NM_001039131
NM_001141
ALOX15B


arachidonate 15-lipoxygenase, type B


chr4_-_73653331 1.082 NM_014243
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr7_+_27190688 1.082


chr18_+_19523526 1.077 NM_001127717
NM_198129
LAMA3

laminin, alpha 3

chr5_+_17270474 1.076 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr18_+_54681657 1.062 ZNF532
zinc finger protein 532
chr1_+_42920635 1.062 NM_004559
YBX1
Y box binding protein 1
chr9_-_109291575 1.057 KLF4
Kruppel-like factor 4 (gut)
chr9_-_95253666 1.057 FAM120AOS
family with sequence similarity 120A opposite strand
chr6_-_76050837 1.055


chr11_-_85108030 1.054 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr5_+_42459568 1.052 NM_000163
GHR
growth hormone receptor
chr3_-_114898003 1.050 NM_001009899
KIAA2018
KIAA2018
chr2_-_29997935 1.049 NM_004304
ALK
anaplastic lymphoma receptor tyrosine kinase
chr2_+_188864640 1.047 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr9_-_109291866 1.045 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr6_-_75972286 1.042 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr11_-_1725924 1.041 NM_001170820
LOC402778
CD225 family protein FLJ76511
chr3_-_12680329 1.036 RAF1
v-raf-1 murine leukemia viral oncogene homolog 1
chr13_-_27092677 1.035 NM_153371
LNX2
ligand of numb-protein X 2
chr9_+_112470871 1.031 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chrX_-_30237403 1.025 NM_000475
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr19_-_36531958 1.014 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr11_-_132318741 1.013 OPCML
opioid binding protein/cell adhesion molecule-like
chr10_-_60792666 1.011 NM_001143773
FAM13C
family with sequence similarity 13, member C
chr14_+_37748345 1.007 SSTR1
somatostatin receptor 1
chr1_+_23218572 1.003 KDM1A
lysine (K)-specific demethylase 1A
chr2_-_74455161 1.000 NM_001135041
NM_023019
DCTN1

dynactin 1

chr9_+_33667169 0.997


chr11_-_47531179 0.995 CELF1
CUGBP, Elav-like family member 1
chr4_+_48038095 0.995 SLAIN2
SLAIN motif family, member 2
chr1_-_52791218 0.993 ZCCHC11
zinc finger, CCHC domain containing 11
chr8_-_13178327 0.984


chr10_-_118021532 0.976 NM_145793
GFRA1
GDNF family receptor alpha 1
chr5_-_54317102 0.975 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr1_-_166172901 0.974 NM_001143674
BRP44
brain protein 44
chr7_-_112513379 0.971 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr1_+_39229474 0.971 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr11_-_111287657 0.969 NM_001885
CRYAB
crystallin, alpha B
chr3_+_151608673 0.968 TSC22D2
TSC22 domain family, member 2
chr5_+_138921507 0.963 UBE2D2
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
chr17_-_37022465 0.959 NM_005557
KRT16
keratin 16
chr19_+_43572679 0.956 NM_001039616
NM_001042522
SPRED3

sprouty-related, EVH1 domain containing 3

chr14_-_90596665 0.956 NM_004755
NM_182398
RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr7_-_106991572 0.956 COG5
component of oligomeric golgi complex 5

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.23 2.27e-15 GO:0044260 cellular macromolecule metabolic process
1.31 4.85e-14 GO:0044267 cellular protein metabolic process
1.26 1.59e-13 GO:0048856 anatomical structure development
1.09 9.81e-13 GO:0009987 cellular process
1.27 1.87e-12 GO:0048731 system development
1.31 4.75e-12 GO:0048523 negative regulation of cellular process
1.18 8.28e-11 GO:0043170 macromolecule metabolic process
1.21 2.24e-10 GO:0032502 developmental process
1.22 6.34e-10 GO:0007275 multicellular organismal development
1.13 3.37e-09 GO:0050794 regulation of cellular process
1.27 3.47e-09 GO:0048519 negative regulation of biological process
1.30 4.49e-09 GO:0006464 protein modification process
1.23 8.88e-09 GO:0019538 protein metabolic process
1.34 1.19e-08 GO:0009653 anatomical structure morphogenesis
1.33 4.07e-08 GO:0007399 nervous system development
1.27 7.85e-08 GO:0030154 cell differentiation
1.27 8.25e-08 GO:0048869 cellular developmental process
1.27 1.80e-07 GO:0043412 macromolecule modification
1.41 2.23e-07 GO:0022008 neurogenesis
1.11 5.09e-07 GO:0050789 regulation of biological process
1.41 7.61e-07 GO:0048699 generation of neurons
1.22 2.66e-06 GO:0048522 positive regulation of cellular process
1.12 2.72e-06 GO:0044237 cellular metabolic process
1.51 5.11e-06 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.38 5.83e-06 GO:0048468 cell development
1.10 7.20e-06 GO:0065007 biological regulation
1.65 7.58e-06 GO:0060284 regulation of cell development
1.27 1.32e-05 GO:0023051 regulation of signaling
1.34 2.03e-05 GO:0006793 phosphorus metabolic process
1.34 2.03e-05 GO:0006796 phosphate metabolic process
1.20 2.36e-05 GO:0071842 cellular component organization at cellular level
1.35 2.90e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.51 3.52e-05 GO:0072358 cardiovascular system development
1.51 3.52e-05 GO:0072359 circulatory system development
1.46 4.05e-05 GO:0048666 neuron development
1.19 4.15e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.31 4.21e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.19 4.82e-05 GO:0048518 positive regulation of biological process
1.37 5.81e-05 GO:0051128 regulation of cellular component organization
1.41 6.45e-05 GO:0030182 neuron differentiation
1.41 6.57e-05 GO:0051254 positive regulation of RNA metabolic process
1.29 9.77e-05 GO:0051239 regulation of multicellular organismal process
1.41 1.13e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.48 1.22e-04 GO:0031175 neuron projection development
1.38 1.29e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.60 1.59e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.38 1.69e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.41 1.92e-04 GO:0045893 positive regulation of transcription, DNA-dependent
1.34 1.96e-04 GO:0050793 regulation of developmental process
1.16 1.96e-04 GO:0016043 cellular component organization
1.39 2.60e-04 GO:0010628 positive regulation of gene expression
1.31 2.73e-04 GO:0010646 regulation of cell communication
1.28 2.96e-04 GO:0009893 positive regulation of metabolic process
1.36 3.29e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.37 3.32e-04 GO:2000026 regulation of multicellular organismal development
1.16 4.01e-04 GO:0071840 cellular component organization or biogenesis
1.26 5.02e-04 GO:0009966 regulation of signal transduction
1.28 5.53e-04 GO:0031325 positive regulation of cellular metabolic process
1.39 6.23e-04 GO:0030030 cell projection organization
1.34 6.27e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.15 7.53e-04 GO:0080090 regulation of primary metabolic process
1.34 7.57e-04 GO:0016310 phosphorylation
1.15 8.17e-04 GO:0031323 regulation of cellular metabolic process
1.37 1.18e-03 GO:0045595 regulation of cell differentiation
1.59 1.21e-03 GO:0051960 regulation of nervous system development
1.33 1.27e-03 GO:0009891 positive regulation of biosynthetic process
1.43 1.47e-03 GO:0000904 cell morphogenesis involved in differentiation
1.42 1.61e-03 GO:0044265 cellular macromolecule catabolic process
1.29 1.67e-03 GO:0042981 regulation of apoptosis
1.10 1.79e-03 GO:0044238 primary metabolic process
1.29 1.81e-03 GO:0043067 regulation of programmed cell death
1.14 1.94e-03 GO:0019222 regulation of metabolic process
1.29 2.00e-03 GO:0007154 cell communication
1.56 2.07e-03 GO:0001944 vasculature development
1.41 2.07e-03 GO:0051253 negative regulation of RNA metabolic process
1.31 2.09e-03 GO:0031324 negative regulation of cellular metabolic process
1.45 2.37e-03 GO:0010648 negative regulation of cell communication
1.30 2.45e-03 GO:0009892 negative regulation of metabolic process
1.28 2.78e-03 GO:0010941 regulation of cell death
1.14 2.86e-03 GO:0023052 signaling
1.31 2.86e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.21 4.53e-03 GO:0010467 gene expression
1.37 4.75e-03 GO:0010629 negative regulation of gene expression
1.37 4.76e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.44 4.80e-03 GO:0048812 neuron projection morphogenesis
1.15 5.02e-03 GO:0060255 regulation of macromolecule metabolic process
1.37 5.09e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.20 5.41e-03 GO:0048513 organ development
1.16 5.52e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.33 5.55e-03 GO:0006468 protein phosphorylation
1.82 5.91e-03 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.39 5.93e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.43 5.99e-03 GO:0023057 negative regulation of signaling
1.35 6.12e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.35 6.37e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.50 6.77e-03 GO:0007411 axon guidance
1.42 6.89e-03 GO:0048646 anatomical structure formation involved in morphogenesis
1.16 7.03e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.11 7.34e-03 GO:0032501 multicellular organismal process
1.44 7.50e-03 GO:0007409 axonogenesis
1.45 7.74e-03 GO:0009968 negative regulation of signal transduction
1.43 7.95e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.80 8.04e-03 GO:0022604 regulation of cell morphogenesis
1.34 8.55e-03 GO:0009890 negative regulation of biosynthetic process
1.55 8.68e-03 GO:0001568 blood vessel development
1.35 9.10e-03 GO:0032989 cellular component morphogenesis
1.36 9.22e-03 GO:0009887 organ morphogenesis
1.57 9.60e-03 GO:0050767 regulation of neurogenesis
1.51 1.02e-02 GO:0032870 cellular response to hormone stimulus
1.08 1.12e-02 GO:0008152 metabolic process
1.35 1.19e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.39 1.24e-02 GO:0048858 cell projection morphogenesis
1.54 1.29e-02 GO:0051101 regulation of DNA binding
1.87 1.36e-02 GO:0010720 positive regulation of cell development
1.31 1.54e-02 GO:0007267 cell-cell signaling
1.35 1.76e-02 GO:0000902 cell morphogenesis
1.26 1.96e-02 GO:0051246 regulation of protein metabolic process
1.20 2.07e-02 GO:0016070 RNA metabolic process
1.26 2.08e-02 GO:0032268 regulation of cellular protein metabolic process
1.38 2.16e-02 GO:0032990 cell part morphogenesis
1.47 2.19e-02 GO:0071495 cellular response to endogenous stimulus
1.60 2.87e-02 GO:0045664 regulation of neuron differentiation
1.39 2.96e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.61 3.13e-02 GO:0007517 muscle organ development
1.47 3.54e-02 GO:0006511 ubiquitin-dependent protein catabolic process
1.16 3.64e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.57 3.65e-02 GO:0048514 blood vessel morphogenesis
1.46 3.87e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
1.46 4.39e-02 GO:0043632 modification-dependent macromolecule catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 8.83e-18 GO:0044424 intracellular part
1.09 1.82e-16 GO:0005622 intracellular
1.10 5.63e-13 GO:0043226 organelle
1.10 7.85e-13 GO:0043229 intracellular organelle
1.22 9.25e-10 GO:0043234 protein complex
1.20 1.42e-09 GO:0032991 macromolecular complex
1.10 2.61e-09 GO:0005737 cytoplasm
1.10 1.66e-08 GO:0043227 membrane-bounded organelle
1.10 2.02e-08 GO:0043231 intracellular membrane-bounded organelle
1.14 6.65e-08 GO:0005634 nucleus
1.12 2.07e-06 GO:0044422 organelle part
1.12 3.31e-06 GO:0044446 intracellular organelle part
1.11 6.85e-05 GO:0044444 cytoplasmic part
1.49 9.63e-05 GO:0043005 neuron projection
1.17 1.05e-04 GO:0043228 non-membrane-bounded organelle
1.17 1.05e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.47 1.62e-04 GO:0045202 synapse
1.03 1.82e-04 GO:0044464 cell part
1.20 1.93e-04 GO:0005829 cytosol
1.03 1.93e-04 GO:0005623 cell
1.23 3.90e-04 GO:0005856 cytoskeleton
1.36 7.40e-04 GO:0030054 cell junction
1.65 7.63e-04 GO:0030425 dendrite
1.18 8.91e-04 GO:0044428 nuclear part
1.22 5.68e-03 GO:0005654 nucleoplasm
1.18 8.50e-03 GO:0031981 nuclear lumen
1.16 1.02e-02 GO:0070013 intracellular organelle lumen
1.16 1.27e-02 GO:0043233 organelle lumen
1.15 1.29e-02 GO:0031974 membrane-enclosed lumen
1.99 1.30e-02 GO:0030427 site of polarized growth
1.29 1.34e-02 GO:0044451 nucleoplasm part
1.99 1.78e-02 GO:0030426 growth cone
1.57 3.96e-02 GO:0070161 anchoring junction
1.60 4.06e-02 GO:0005912 adherens junction
1.22 4.72e-02 GO:0044430 cytoskeletal part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.18 6.03e-24 GO:0005515 protein binding
1.07 4.58e-11 GO:0005488 binding
1.38 5.66e-08 GO:0030528 transcription regulator activity
1.41 5.43e-06 GO:0043565 sequence-specific DNA binding
1.20 2.91e-05 GO:0000166 nucleotide binding
1.29 7.03e-04 GO:0001071 nucleic acid binding transcription factor activity
1.29 7.03e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.52 8.85e-04 GO:0016564 transcription repressor activity
1.22 1.00e-03 GO:0032559 adenyl ribonucleotide binding
1.22 1.05e-03 GO:0030554 adenyl nucleotide binding
1.33 1.10e-03 GO:0019899 enzyme binding
1.19 1.84e-03 GO:0032553 ribonucleotide binding
1.19 1.84e-03 GO:0032555 purine ribonucleotide binding
1.19 2.20e-03 GO:0017076 purine nucleotide binding
1.18 7.69e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.20 1.08e-02 GO:0005524 ATP binding
1.44 1.64e-02 GO:0016563 transcription activator activity
1.44 3.52e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.46 4.48e-02 GO:0016881 acid-amino acid ligase activity