Motif ID: MYBL2.p2

Z-value: 1.913


Transcription factors associated with MYBL2.p2:

Gene SymbolEntrez IDGene Name
MYBL2 4605 v-myb myeloblastosis viral oncogene homolog (avian)-like 2



Activity profile for motif MYBL2.p2.

activity profile for motif MYBL2.p2


Sorted Z-values histogram for motif MYBL2.p2

Sorted Z-values for motif MYBL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYBL2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_198248828 8.475 NM_144629
RFTN2
raftlin family member 2
chr17_-_46479127 6.123 SPAG9
sperm associated antigen 9
chr5_+_155686750 6.014 SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr15_+_55298908 5.497 NM_207040
TCF12
transcription factor 12
chr2_+_151922350 5.307 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr9_-_94338072 4.792 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr3_-_115960807 4.195 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr3_+_158637273 4.114 NM_002852
PTX3
pentraxin 3, long
chrX_-_33139349 4.010 NM_004006
DMD
dystrophin
chr11_-_85107569 3.824 NM_206929
SYTL2
synaptotagmin-like 2
chr15_-_40537002 3.714 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr16_+_14187965 3.608 MKL2
MKL/myocardin-like 2
chr11_-_85108030 3.570 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr9_+_119506428 3.570 TLR4
toll-like receptor 4
chr17_-_15495534 3.487 TRIM16
tripartite motif containing 16
chr9_+_119506446 3.483 TLR4
toll-like receptor 4
chr3_+_100840129 3.430 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr15_+_41597097 3.337 NM_002373
MAP1A
microtubule-associated protein 1A
chr5_-_54317102 3.259 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr1_+_168898898 3.220 PRRX1
paired related homeobox 1
chr1_+_84402962 3.158 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_+_79362256 3.062 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr3_-_124821868 3.006 MYLK
myosin light chain kinase
chr1_-_149047329 2.842 NM_000396
CTSK
cathepsin K
chr1_-_191422346 2.726 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr4_+_120276386 2.679 NM_016599
MYOZ2
myozenin 2
chr4_+_14950657 2.633 NM_001135170
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr15_+_47502666 2.542 NM_002009
FGF7
fibroblast growth factor 7
chr12_+_7039453 2.523


chr4_-_122357104 2.451 NM_001128843
TNIP3
TNFAIP3 interacting protein 3
chr11_-_85103438 2.356 NM_032379
SYTL2
synaptotagmin-like 2
chr3_+_35696119 2.349 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr6_+_152053323 2.346 NM_001122742
ESR1
estrogen receptor 1
chr2_+_170074457 2.333 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr1_-_197173159 2.268 LOC100131234
familial acute myelogenous leukemia related factor
chr3_-_113841448 2.265 CCDC80
coiled-coil domain containing 80
chr4_+_148621694 2.222 EDNRA
endothelin receptor type A
chr5_+_155686333 2.143 NM_000337
NM_001128209
NM_172244
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr8_-_17599438 2.105 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr4_+_3341521 2.040 NM_198227
RGS12
regulator of G-protein signaling 12
chr9_+_18464090 2.036 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr10_+_17310263 2.016 NM_003380
VIM
vimentin
chr9_+_71848316 1.945 NM_153267
MAMDC2
MAM domain containing 2
chr4_+_114190233 1.907 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr1_+_20269239 1.879 NM_000929
PLA2G5
phospholipase A2, group V
chr7_-_81237162 1.872 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr6_-_112186977 1.861 NM_153048
FYN
FYN oncogene related to SRC, FGR, YES
chr1_-_20682541 1.814


chr19_-_13808101 1.791 LOC284454
hypothetical LOC284454
chr4_+_77575276 1.789 NM_020859
SHROOM3
shroom family member 3
chr9_+_119506274 1.788 NM_138554
TLR4
toll-like receptor 4
chr1_+_208472817 1.778 NM_019605
SERTAD4
SERTA domain containing 4
chrX_-_77801480 1.760 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chr3_+_189413414 1.755 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr6_-_169392771 1.732


chr8_-_19504285 1.729 NM_001130518
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr10_+_17310475 1.714 VIM
vimentin
chr4_+_148621567 1.691 EDNRA
endothelin receptor type A
chr1_+_84539876 1.689 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr12_+_76749199 1.688 NM_014903
NAV3
neuron navigator 3
chr3_-_124822113 1.658 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr3_-_27473248 1.654 NM_003615
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr8_-_122722674 1.651 NM_005328
HAS2
hyaluronan synthase 2
chr2_-_134042500 1.641 NM_207363
NM_207481
NCKAP5

NCK-associated protein 5

chr1_+_159943385 1.629 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr5_-_94442941 1.627 MCTP1
multiple C2 domains, transmembrane 1
chr8_-_93144039 1.616


chr14_-_88086559 1.613 PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr11_-_35503720 1.604 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr1_+_19807168 1.591


chr1_+_15145001 1.590 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr4_+_148621518 1.548 NM_001166055
NM_001957
EDNRA

endothelin receptor type A

chr7_+_28418668 1.543 NM_182898
CREB5
cAMP responsive element binding protein 5
chr3_-_188935363 1.539 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr21_+_29439768 1.526 C21orf7
chromosome 21 open reading frame 7
chr19_-_13478037 1.525 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr10_-_98315090 1.520 TM9SF3
transmembrane 9 superfamily member 3
chr2_+_210152399 1.494 MAP2
microtubule-associated protein 2
chr15_+_65205107 1.449 NM_001145102
SMAD3
SMAD family member 3
chr3_-_50583425 1.439 NM_001171741
C3orf18
chromosome 3 open reading frame 18
chr4_-_39199527 1.435 UGDH
UDP-glucose 6-dehydrogenase
chr12_+_32578513 1.412 FGD4
FYVE, RhoGEF and PH domain containing 4
chr11_+_101488380 1.383 NM_001195045
YAP1
Yes-associated protein 1
chr1_+_165330710 1.378 NM_001080426
DUSP27
dual specificity phosphatase 27 (putative)
chr5_-_94443300 1.376 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr3_-_113841200 1.372 CCDC80
coiled-coil domain containing 80
chr11_-_111287657 1.362 NM_001885
CRYAB
crystallin, alpha B
chr2_-_227952249 1.340 NM_024795
TM4SF20
transmembrane 4 L six family member 20
chr18_-_3864252 1.337 DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr9_-_116190038 1.308 AKNA
AT-hook transcription factor
chr2_-_40510923 1.294 NM_001112800
NM_001112801
NM_021097
SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chrX_+_135106578 1.278 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr12_-_55929189 1.274


chr6_-_127822227 1.266 NM_014702
KIAA0408
KIAA0408
chr13_-_102144854 1.265 NM_001010977
METTL21C
methyltransferase like 21C
chr13_+_100902942 1.263 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr5_+_36644187 1.261 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_-_113841967 1.220 CCDC80
coiled-coil domain containing 80
chr12_-_16649211 1.217 LMO3
LIM domain only 3 (rhombotin-like 2)
chr5_-_58607673 1.209 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_+_1094248 1.195 NM_001098201
GPER
G protein-coupled estrogen receptor 1
chr15_-_23201740 1.192 NM_130838
UBE3A
ubiquitin protein ligase E3A
chr2_-_189752575 1.191 NM_000393
COL5A2
collagen, type V, alpha 2
chr1_-_110735158 1.191 NM_004696
SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr9_-_72219359 1.177 NM_001206
KLF9
Kruppel-like factor 9
chr12_+_5411534 1.147 NM_001102654
NTF3
neurotrophin 3
chr9_+_71848555 1.143 MAMDC2
MAM domain containing 2
chr6_+_45404031 1.135 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr3_-_113841941 1.116 CCDC80
coiled-coil domain containing 80
chr2_+_190710730 1.097 NM_001042521
C2orf88
chromosome 2 open reading frame 88
chr3_-_49372584 1.094 RHOA
ras homolog gene family, member A
chr12_+_20739555 1.080 NM_001145945
NM_001145946
NM_001145944
NM_017435
SLCO1C1



solute carrier organic anion transporter family, member 1C1



chr18_+_70471906 1.077 NM_001146189
NM_001146190
NM_017757
ZNF407


zinc finger protein 407


chr13_-_59223074 1.066


chr13_-_48873735 1.056 NM_030925
CAB39L
calcium binding protein 39-like
chrX_+_153952868 1.054 NM_001018055
NM_024332
BRCC3

BRCA1/BRCA2-containing complex, subunit 3

chr5_+_36642424 1.045 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_-_93181091 1.019 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_152299229 1.011 NM_001164507
NM_001164508
NM_004543
NEB


nebulin


chr7_+_28497272 1.010 CREB5
cAMP responsive element binding protein 5
chr13_-_47885018 1.003 LPAR6
lysophosphatidic acid receptor 6
chr5_-_90645974 0.998 LOC100505994
hypothetical LOC100505994
chr16_+_55373241 0.983 NUP93
nucleoporin 93kDa
chr1_-_171838802 0.979 NM_178527
SLC9A11
solute carrier family 9, member 11
chr2_+_138438277 0.975 NM_001024074
NM_001024075
NM_006895
HNMT


histamine N-methyltransferase


chr11_-_76676110 0.952 NM_182833
GDPD4
glycerophosphodiester phosphodiesterase domain containing 4
chr7_+_129771865 0.940 NM_001127441
NM_001127442
NM_080385
CPA5


carboxypeptidase A5


chr10_-_100985548 0.913 NM_001166244
NM_001166245
NM_001166246
NM_021828
HPSE2



heparanase 2



chr5_+_88221013 0.904 RPS6
ribosomal protein S6
chr12_-_15757114 0.899 EPS8
epidermal growth factor receptor pathway substrate 8
chr8_+_107807415 0.897 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr4_-_149577404 0.893


chr2_+_210152609 0.882 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr13_+_23042722 0.882 NM_148957
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr20_+_11846536 0.877 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr1_+_199426575 0.875 NM_001164586
IGFN1
immunoglobulin-like and fibronectin type III domain containing 1
chr5_+_67558217 0.872 NM_181523
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr3_-_130600931 0.858 RPL32P3
ribosomal protein L32 pseudogene 3
chr12_+_94200306 0.848 VEZT
vezatin, adherens junctions transmembrane protein
chr1_-_42549347 0.834


chr11_-_124048808 0.831 NM_170601
SIAE
sialic acid acetylesterase
chr3_-_113842133 0.829 CCDC80
coiled-coil domain containing 80
chr7_+_93388951 0.824 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr2_+_166034402 0.824 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chr2_+_96672200 0.810 NM_001113382
FER1L5
fer-1-like 5 (C. elegans)
chrX_-_10548458 0.807 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr1_-_143786993 0.801 NM_022359
PDE4DIP
phosphodiesterase 4D interacting protein
chr3_+_185520744 0.798 NM_004953
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr1_-_103269356 0.796 COL11A1
collagen, type XI, alpha 1
chr13_-_47885248 0.794 LPAR6
lysophosphatidic acid receptor 6
chr3_+_150028130 0.789 NM_001871
CPB1
carboxypeptidase B1 (tissue)
chr4_+_120167264 0.788 SYNPO2
synaptopodin 2
chr1_+_169747788 0.787 PRRC2C
proline-rich coiled-coil 2C
chr10_-_28611020 0.785 NM_173496
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr1_-_93172119 0.774


chr9_+_96806235 0.774 C9orf3
chromosome 9 open reading frame 3
chr4_-_148086413 0.770 NM_031956
TTC29
tetratricopeptide repeat domain 29
chr9_-_36266930 0.762 NM_001128227
NM_001190388
GNE

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr1_+_31655607 0.753 NM_001199037
SERINC2
serine incorporator 2
chr1_+_161305019 0.753 NM_001102445
RGS4
regulator of G-protein signaling 4
chrX_-_11194015 0.753 NM_013423
ARHGAP6
Rho GTPase activating protein 6
chr3_-_113842652 0.731 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr6_-_32184975 0.728 NM_019105
TNXB
tenascin XB
chr6_-_117853710 0.722 NM_002944
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr6_-_152744022 0.720 SYNE1
spectrin repeat containing, nuclear envelope 1
chr12_-_26169074 0.705 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr8_-_132122016 0.705 NM_001115
ADCY8
adenylate cyclase 8 (brain)
chr22_-_37211467 0.704 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chrX_+_100220491 0.700 NM_021637
TMEM35
transmembrane protein 35
chr3_+_171621721 0.699 NM_001185056
CLDN11
claudin 11
chr9_+_115396020 0.692 NM_144489
RGS3
regulator of G-protein signaling 3
chr4_+_146820805 0.689 NM_001080531
C4orf51
chromosome 4 open reading frame 51
chr11_+_128069203 0.673 FLI1
Friend leukemia virus integration 1
chr2_+_182558795 0.672 NM_001080545
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr2_-_213723298 0.672 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr11_-_5321329 0.669 NM_001005567
OR51B5
olfactory receptor, family 51, subfamily B, member 5
chr11_-_84311867 0.667 DLG2
discs, large homolog 2 (Drosophila)
chr7_+_120416680 0.666 NM_001105533
C7orf58
chromosome 7 open reading frame 58
chr5_-_39461054 0.666 NM_001343
DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr3_-_113842553 0.662 CCDC80
coiled-coil domain containing 80
chr11_+_5329313 0.655 NM_001004750
OR51B6
olfactory receptor, family 51, subfamily B, member 6
chr6_-_56220274 0.652 NM_030820
COL21A1
collagen, type XXI, alpha 1
chr1_+_143326315 0.649 NM_001037675
NBPF10
NBPF9
NBPF8
neuroblastoma breakpoint family, member 10
neuroblastoma breakpoint family, member 9
neuroblastoma breakpoint family, member 8
chr11_+_124048949 0.648 NM_017425
SPA17
sperm autoantigenic protein 17
chr12_+_54400417 0.645 NM_002905
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr4_+_15038726 0.637 NM_031911
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr2_-_224175386 0.632 NM_003469
SCG2
secretogranin II
chr13_+_110565587 0.628 NM_001113511
NM_001113512
NM_145735
ARHGEF7


Rho guanine nucleotide exchange factor (GEF) 7


chr7_+_80105858 0.627 CD36
CD36 molecule (thrombospondin receptor)
chr17_-_44047299 0.627 NM_024016
HOXB8
homeobox B8
chr2_+_84597087 0.627 NM_001370
DNAH6
dynein, axonemal, heavy chain 6
chr7_+_119700924 0.623 NM_012281
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr11_+_128069340 0.620 FLI1
Friend leukemia virus integration 1
chr3_+_115099007 0.603 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr7_+_18501876 0.597 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr2_+_66519949 0.593 MEIS1
Meis homeobox 1
chr11_-_127962662 0.591 NM_001143820
ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr11_+_32994303 0.590 NM_139160
DEPDC7
DEP domain containing 7
chr15_-_81037554 0.586 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr17_+_7753428 0.584 CHD3
chromodomain helicase DNA binding protein 3

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
3.85 1.39e-04 GO:0043292 contractile fiber
3.97 1.74e-04 GO:0044449 contractile fiber part
3.86 2.59e-04 GO:0030016 myofibril
3.81 2.48e-03 GO:0030017 sarcomere

Nothing significant found in function category.