Motif ID: MZF1.p2

Z-value: 5.077


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1



Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_108665168 9.619 NM_021224
ZNF462
zinc finger protein 462
chr2_-_216944911 9.264 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr8_+_22513043 8.407 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr7_-_27120015 8.163 HOXA3
homeobox A3
chr21_-_27261276 7.910 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr19_-_36531958 7.310 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chrX_+_154650590 6.319 NM_005840
SPRY3
sprouty homolog 3 (Drosophila)
chr5_-_127901633 5.496 NM_001999
FBN2
fibrillin 2
chr5_+_17270474 5.452 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr10_+_71231693 5.236 COL13A1
collagen, type XIII, alpha 1
chr5_+_17270781 5.224 BASP1
brain abundant, membrane attached signal protein 1
chr6_+_21774624 5.159 FLJ22536
hypothetical locus LOC401237
chr10_-_105604942 5.029 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr19_+_12996745 4.965 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr3_-_189354510 4.904 LOC339929
hypothetical LOC339929
chr13_+_87122778 4.846 NM_015567
SLITRK5
SLIT and NTRK-like family, member 5
chr2_-_152663454 4.770 NM_001005746
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr17_-_69151821 4.743 NM_001144952
SDK2
sidekick homolog 2 (chicken)
chr3_+_148610516 4.659 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr3_+_189354167 4.644 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr7_-_78920806 4.643 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr18_+_54682261 4.339 ZNF532
zinc finger protein 532
chr10_-_79067210 4.317 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr1_+_2975590 4.299 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr15_+_66658626 4.276 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr15_-_86600658 4.244 NM_001007156
NM_001012338
NM_002530
NTRK3


neurotrophic tyrosine kinase, receptor, type 3


chr8_+_30361485 4.221 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr7_+_78920846 4.204 LOC100505881
hypothetical LOC100505881
chr19_+_12996830 4.190 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr4_+_30330963 4.187 NM_001173523
NM_002589
NM_032456
NM_032457
PCDH7



protocadherin 7



chr20_+_51022352 4.153 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr4_+_37569093 4.100 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr7_-_27136876 4.056 NM_002141
HOXA4
homeobox A4
chrX_+_12066505 4.053 NM_014728
FRMPD4
FERM and PDZ domain containing 4
chr5_-_9599157 4.024 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr10_+_71231649 4.017 NM_001130103
NM_080798
NM_080800
NM_080801
NM_080802
NM_080805
COL13A1





collagen, type XIII, alpha 1





chr2_+_45022540 4.010 NM_005413
SIX3
SIX homeobox 3
chr17_+_7728819 3.997 NM_001005271
CHD3
chromodomain helicase DNA binding protein 3
chr17_+_18255753 3.862 FLJ35934
FLJ35934
chr6_+_17501589 3.862 NM_006366
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chrX_+_73557809 3.841 NM_006517
SLC16A2
solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr13_-_43259032 3.840 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr12_-_51912101 3.817 NM_000966
RARG
retinoic acid receptor, gamma
chr11_-_27700180 3.798 NM_170731
BDNF
brain-derived neurotrophic factor
chr1_-_72521079 3.797


chr2_-_152663748 3.784 NM_000726
NM_001145798
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr17_-_24068759 3.730 NM_001144942
NM_031934
RAB34

RAB34, member RAS oncogene family

chr1_-_72520735 3.703 NM_173808
NEGR1
neuronal growth regulator 1
chr19_-_242335 3.691 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr4_+_30331289 3.648 PCDH7
protocadherin 7
chr11_-_27697768 3.627 NM_001143807
BDNF
brain-derived neurotrophic factor
chrX_+_100361588 3.594 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr9_-_20612433 3.551 MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr22_-_34566276 3.517 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr19_-_242168 3.477 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr9_+_8848130 3.477


chr4_+_145786622 3.473 NM_022475
HHIP
hedgehog interacting protein
chr6_-_72187168 3.465 C6orf155
chromosome 6 open reading frame 155
chr18_-_55515552 3.451 CCBE1
collagen and calcium binding EGF domains 1
chr6_-_10523424 3.427 NM_003220
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr9_-_121171400 3.420 NM_014618
DBC1
deleted in bladder cancer 1
chr7_+_55054152 3.415 NM_005228
NM_201282
NM_201283
NM_201284
EGFR



epidermal growth factor receptor



chr12_-_47468985 3.401 NM_020983
ADCY6
adenylate cyclase 6
chr19_-_59676153 3.371 NM_145057
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr8_+_123863224 3.370 ZHX2
zinc fingers and homeoboxes 2
chrX_+_66680593 3.301 NM_000044
AR
androgen receptor
chr5_+_152850276 3.284 NM_000827
NM_001114183
GRIA1

glutamate receptor, ionotropic, AMPA 1

chr18_-_55515623 3.282 NM_133459
CCBE1
collagen and calcium binding EGF domains 1
chr10_+_73393998 3.272 NM_004273
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr5_+_92944680 3.240 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr8_-_89408832 3.239 NM_005941
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr4_-_11039600 3.228 NM_005114
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr1_+_15957832 3.223 NM_017556
FBLIM1
filamin binding LIM protein 1
chr19_+_12996368 3.216 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr14_+_85069217 3.213


chr2_-_161058550 3.195 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr19_-_55914837 3.191


chr4_-_158111995 3.189 NM_016205
PDGFC
platelet derived growth factor C
chr14_-_36059084 3.187 NM_001079668
NKX2-1
NK2 homeobox 1
chr2_-_165186064 3.178 GRB14
growth factor receptor-bound protein 14
chr9_-_20612476 3.165 NM_004529
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr2_-_56004366 3.155 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr19_+_43572679 3.153 NM_001039616
NM_001042522
SPRED3

sprouty-related, EVH1 domain containing 3

chr3_-_64648703 3.127 ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr1_+_199884072 3.117 NM_020443
NAV1
neuron navigator 1
chr20_-_30534848 3.114 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr8_+_95722448 3.102 ESRP1
epithelial splicing regulatory protein 1
chr5_+_79021401 3.099 NM_153610
CMYA5
cardiomyopathy associated 5
chr6_-_75972473 3.093 COL12A1
collagen, type XII, alpha 1
chr17_+_7096095 3.078 NM_203415
NM_015362
NM_203413
NM_203414
C17orf81



chromosome 17 open reading frame 81



chr13_+_113574925 3.075 NM_001143945
GAS6
growth arrest-specific 6
chr11_+_36354110 3.070 NM_001160168
NM_024841
PRR5L

proline rich 5 like

chr2_-_165186232 3.068 GRB14
growth factor receptor-bound protein 14
chr16_-_63713485 3.025 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr11_-_27677755 3.018 NM_170734
BDNF
brain-derived neurotrophic factor
chr22_-_34566210 3.010 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr20_-_30535045 2.994 C20orf112
chromosome 20 open reading frame 112
chr17_-_44047299 2.988 NM_024016
HOXB8
homeobox B8
chr19_-_56196611 2.988 NM_007196
NM_144505
NM_144506
NM_144507
KLK8



kallikrein-related peptidase 8



chr9_+_138341752 2.961 NM_001145638
NM_015597
GPSM1

G-protein signaling modulator 1

chr6_-_112682459 2.958 NM_001105206
NM_001105207
NM_001105208
NM_001105209
NM_002290
LAMA4




laminin, alpha 4




chr10_+_119292699 2.958


chr5_-_92942680 2.946 FLJ42709
hypothetical LOC441094
chr4_-_158111916 2.912 PDGFC
platelet derived growth factor C
chr16_-_63713466 2.899 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr19_-_56178882 2.885 NM_139277
NM_005046
KLK7

kallikrein-related peptidase 7

chr12_-_105056577 2.878 NUAK1
NUAK family, SNF1-like kinase, 1
chr16_-_52877868 2.869 NM_024336
IRX3
iroquois homeobox 3
chr17_-_959007 2.865 NM_001092
ABR
active BCR-related gene
chr3_-_121652183 2.861 NM_007085
FSTL1
follistatin-like 1
chr4_-_1097313 2.861 NM_001131034
NM_001193318
NM_194439
RNF212


ring finger protein 212


chr12_+_52689062 2.856 NM_022658
HOXC8
homeobox C8
chr1_+_199884152 2.825 NAV1
neuron navigator 1
chr5_+_82803248 2.804 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr1_+_213323182 2.765 NM_001017425
NM_014217
KCNK2

potassium channel, subfamily K, member 2

chr19_-_41215380 2.759 CLIP3
CAP-GLY domain containing linker protein 3
chr12_+_74071145 2.747 NM_152436
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr18_-_22382497 2.746 NM_001142730
KCTD1
potassium channel tetramerisation domain containing 1
chr12_+_64504835 2.733 HMGA2
high mobility group AT-hook 2
chr22_-_28972683 2.714 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr6_+_121798443 2.709 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr16_-_63713382 2.689 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr6_-_10523203 2.669 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr1_+_162795328 2.645 NM_002585
PBX1
pre-B-cell leukemia homeobox 1
chr22_+_29974368 2.632 LIMK2
LIM domain kinase 2
chr2_-_110230642 2.628 MALL
mal, T-cell differentiation protein-like
chr2_-_237080830 2.618 NM_024726
IQCA1
IQ motif containing with AAA domain 1
chr20_+_52525538 2.614 NM_018431
DOK5
docking protein 5
chr20_-_3713509 2.603 CENPB
centromere protein B, 80kDa
chr12_+_70952729 2.599 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr1_-_103346482 2.592 COL11A1
collagen, type XI, alpha 1
chr1_-_68470585 2.584 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr1_+_47261826 2.573 NM_178033
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr12_+_74071116 2.572 GLIPR1L2
GLI pathogenesis-related 1 like 2
chr4_+_41057600 2.568


chr5_-_168660293 2.567 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr21_+_46226072 2.544 NM_001848
COL6A1
collagen, type VI, alpha 1
chr22_-_34566367 2.542 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr6_+_41714171 2.538 NM_005586
MDFI
MyoD family inhibitor
chr7_+_114350144 2.528 MDFIC
MyoD family inhibitor domain containing
chr10_-_79067296 2.520 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr10_-_126839546 2.516 NM_001083914
CTBP2
C-terminal binding protein 2
chr10_+_102495327 2.508 NM_000278
NM_003987
NM_003988
NM_003989
NM_003990
PAX2




paired box 2




chr2_-_161058120 2.506 RBMS1
RNA binding motif, single stranded interacting protein 1
chrX_-_54401161 2.504 NM_001002838
NM_020922
WNK3

WNK lysine deficient protein kinase 3

chr12_+_52653176 2.504 NM_014212
HOXC11
homeobox C11
chr3_-_13896618 2.477 NM_004625
WNT7A
wingless-type MMTV integration site family, member 7A
chr11_-_132318741 2.477 OPCML
opioid binding protein/cell adhesion molecule-like
chr18_-_33399601 2.471 CELF4
CUGBP, Elav-like family member 4
chr9_+_35528890 2.470 RUSC2
RUN and SH3 domain containing 2
chr15_-_59308708 2.469 RORA
RAR-related orphan receptor A
chr5_+_129268352 2.461 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr22_-_26527469 2.452 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr4_+_81406765 2.414 NM_004464
NM_033143
FGF5

fibroblast growth factor 5

chr9_+_90796169 2.408 NM_005226
S1PR3
sphingosine-1-phosphate receptor 3
chr2_+_137239583 2.408 THSD7B
thrombospondin, type I, domain containing 7B
chr14_-_36058648 2.407 NM_003317
NKX2-1
NK2 homeobox 1
chr4_+_183302105 2.406 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chrX_+_71047344 2.394 NM_001013627
NHSL2
NHS-like 2
chr2_+_39746525 2.390 NM_152390
TMEM178
transmembrane protein 178
chr4_+_61749540 2.390 LPHN3
latrophilin 3
chr1_+_218768423 2.364 MARK1
MAP/microtubule affinity-regulating kinase 1
chr15_+_65904994 2.337 NM_001031807
SKOR1
SKI family transcriptional corepressor 1
chr3_-_56477404 2.336 NM_015576
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr11_+_61352348 2.325 FADS2
fatty acid desaturase 2
chr11_+_86189138 2.297 NM_007173
PRSS23
protease, serine, 23
chr7_-_19123765 2.296 TWIST1
twist homolog 1 (Drosophila)
chr19_-_13478037 2.295 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr17_-_24069299 2.294 NM_001142624
NM_001142625
NM_001144943
RAB34


RAB34, member RAS oncogene family


chr5_+_131437383 2.290 NM_000758
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr8_-_11096257 2.284 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr13_-_39075200 2.281 LHFP
lipoma HMGIC fusion partner
chr2_+_210344972 2.279 UNC80
unc-80 homolog (C. elegans)
chr6_-_80713589 2.272 NM_022726
ELOVL4
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
chr12_-_94708641 2.272 NM_021229
NTN4
netrin 4
chr15_-_59308770 2.265 NM_134261
RORA
RAR-related orphan receptor A
chr19_-_54258935 2.264 NM_006179
NTF4
neurotrophin 4
chr7_-_127458231 2.263 NM_022143
LRRC4
leucine rich repeat containing 4
chr1_-_103346639 2.253 NM_001190709
NM_001854
NM_080629
NM_080630
COL11A1



collagen, type XI, alpha 1



chr4_+_93444572 2.245 NM_001510
GRID2
glutamate receptor, ionotropic, delta 2
chr5_-_83716346 2.239 NM_005711
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr2_+_217206450 2.236 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr10_-_79067552 2.234 NM_001014797
NM_001161352
NM_001161353
NM_002247
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr2_+_36436316 2.233 CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr11_-_56846246 2.224 TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr18_+_17076166 2.215 NM_001142966
GREB1L
growth regulation by estrogen in breast cancer-like
chr17_-_7095622 2.214 NM_001143775
CTDNEP1
CTD nuclear envelope phosphatase 1
chr13_+_49469138 2.213 NM_001007278
NM_005798
NM_052811
NM_213590
TRIM13



tripartite motif containing 13



chr1_-_34404029 2.193 NM_052896
CSMD2
CUB and Sushi multiple domains 2
chr12_-_26169074 2.180 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr2_-_110230822 2.174 MALL
mal, T-cell differentiation protein-like
chr2_+_210344945 2.173 NM_032504
NM_182587
UNC80

unc-80 homolog (C. elegans)

chr4_-_96689137 2.167 UNC5C
unc-5 homolog C (C. elegans)
chr2_-_60633908 2.158 NM_018014
NM_022893
NM_138559
BCL11A


B-cell CLL/lymphoma 11A (zinc finger protein)


chr2_+_69093641 2.150 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr2_-_45090025 2.148 NM_016932
SIX2
SIX homeobox 2
chr12_-_6313219 2.146 TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr10_-_79067476 2.134 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr4_-_158111504 2.129 PDGFC
platelet derived growth factor C
chr8_+_1909437 2.127 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.37 2.52e-20 GO:0007399 nervous system development
1.13 9.16e-20 GO:0050789 regulation of biological process
1.14 1.00e-19 GO:0050794 regulation of cellular process
1.12 2.02e-19 GO:0065007 biological regulation
1.23 8.07e-17 GO:0048731 system development
1.43 2.86e-16 GO:0022008 neurogenesis
1.33 3.65e-16 GO:0009653 anatomical structure morphogenesis
1.21 1.27e-15 GO:0048856 anatomical structure development
1.07 1.51e-15 GO:0009987 cellular process
1.23 1.55e-15 GO:0048518 positive regulation of biological process
1.24 6.11e-15 GO:0048522 positive regulation of cellular process
1.19 9.02e-15 GO:0007275 multicellular organismal development
1.42 2.76e-14 GO:0048699 generation of neurons
1.18 1.07e-13 GO:0023052 signaling
1.18 2.61e-13 GO:0032502 developmental process
1.25 6.67e-13 GO:0030154 cell differentiation
1.44 2.20e-12 GO:0030182 neuron differentiation
1.24 6.19e-12 GO:0048869 cellular developmental process
1.22 1.51e-11 GO:0048519 negative regulation of biological process
1.36 2.92e-11 GO:0048468 cell development
1.23 4.41e-11 GO:0048523 negative regulation of cellular process
1.16 2.26e-10 GO:0031323 regulation of cellular metabolic process
1.17 3.82e-10 GO:0007165 signal transduction
1.33 1.31e-09 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.25 3.40e-09 GO:0023051 regulation of signaling
1.35 5.69e-09 GO:0051128 regulation of cellular component organization
1.45 5.85e-09 GO:0000904 cell morphogenesis involved in differentiation
1.15 6.73e-09 GO:0080090 regulation of primary metabolic process
1.33 9.77e-09 GO:0031324 negative regulation of cellular metabolic process
1.26 1.08e-08 GO:0009966 regulation of signal transduction
1.42 1.38e-08 GO:0048666 neuron development
1.39 2.19e-08 GO:0007167 enzyme linked receptor protein signaling pathway
1.22 2.47e-08 GO:0048583 regulation of response to stimulus
1.35 3.06e-08 GO:0051173 positive regulation of nitrogen compound metabolic process
1.12 4.88e-08 GO:0043170 macromolecule metabolic process
1.14 5.01e-08 GO:0019222 regulation of metabolic process
1.39 7.47e-08 GO:0009887 organ morphogenesis
1.30 8.60e-08 GO:0009892 negative regulation of metabolic process
1.34 1.06e-07 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38 1.17e-07 GO:0032989 cellular component morphogenesis
1.38 1.22e-07 GO:0045893 positive regulation of transcription, DNA-dependent
1.36 1.75e-07 GO:0010628 positive regulation of gene expression
1.31 1.84e-07 GO:0006351 transcription, DNA-dependent
1.36 2.01e-07 GO:0031327 negative regulation of cellular biosynthetic process
1.76 2.26e-07 GO:0045165 cell fate commitment
1.35 2.50e-07 GO:0009890 negative regulation of biosynthetic process
1.15 2.65e-07 GO:0060255 regulation of macromolecule metabolic process
1.38 2.68e-07 GO:0000902 cell morphogenesis
1.42 2.82e-07 GO:0031175 neuron projection development
1.13 2.89e-07 GO:0051716 cellular response to stimulus
1.36 4.02e-07 GO:0051254 positive regulation of RNA metabolic process
1.20 6.12e-07 GO:0048513 organ development
1.30 7.79e-07 GO:0050793 regulation of developmental process
1.35 8.45e-07 GO:0010558 negative regulation of macromolecule biosynthetic process
1.36 9.39e-07 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.34 1.28e-06 GO:0045595 regulation of cell differentiation
1.29 1.36e-06 GO:0010605 negative regulation of macromolecule metabolic process
1.30 1.69e-06 GO:0031328 positive regulation of cellular biosynthetic process
1.26 1.73e-06 GO:0010604 positive regulation of macromolecule metabolic process
1.25 1.96e-06 GO:0031325 positive regulation of cellular metabolic process
1.46 2.04e-06 GO:0048598 embryonic morphogenesis
1.12 2.29e-06 GO:0044260 cellular macromolecule metabolic process
1.32 2.44e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
1.16 3.75e-06 GO:0031326 regulation of cellular biosynthetic process
1.42 3.82e-06 GO:0048667 cell morphogenesis involved in neuron differentiation
1.44 3.85e-06 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.24 4.21e-06 GO:0009893 positive regulation of metabolic process
1.29 4.91e-06 GO:0009891 positive regulation of biosynthetic process
1.37 5.13e-06 GO:0045892 negative regulation of transcription, DNA-dependent
1.16 5.28e-06 GO:0009889 regulation of biosynthetic process
1.24 5.45e-06 GO:0051239 regulation of multicellular organismal process
1.37 5.70e-06 GO:0051253 negative regulation of RNA metabolic process
1.56 6.01e-06 GO:0003002 regionalization
1.31 6.68e-06 GO:2000026 regulation of multicellular organismal development
1.34 6.68e-06 GO:0030030 cell projection organization
1.27 1.01e-05 GO:0032774 RNA biosynthetic process
1.09 1.04e-05 GO:0044238 primary metabolic process
1.37 1.08e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.16 1.12e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.49 1.22e-05 GO:0048729 tissue morphogenesis
1.15 1.33e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.44 1.56e-05 GO:0043009 chordate embryonic development
1.34 1.67e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
1.34 1.77e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.45 1.81e-05 GO:0007389 pattern specification process
1.31 1.95e-05 GO:0009790 embryo development
1.50 1.97e-05 GO:0035295 tube development
1.39 2.38e-05 GO:0048812 neuron projection morphogenesis
1.43 2.48e-05 GO:0009792 embryo development ending in birth or egg hatching
1.40 2.55e-05 GO:0007409 axonogenesis
1.16 2.61e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.33 3.16e-05 GO:0010629 negative regulation of gene expression
1.15 3.34e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.47 3.45e-05 GO:0051130 positive regulation of cellular component organization
1.37 4.13e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.13 4.93e-05 GO:0016043 cellular component organization
1.49 6.44e-05 GO:0001568 blood vessel development
1.18 9.64e-05 GO:0007166 cell surface receptor linked signaling pathway
1.15 1.03e-04 GO:0071842 cellular component organization at cellular level
1.15 1.20e-04 GO:0010468 regulation of gene expression
1.18 1.32e-04 GO:0006464 protein modification process
1.25 1.40e-04 GO:0032879 regulation of localization
1.07 1.67e-04 GO:0008152 metabolic process
1.61 1.98e-04 GO:0009952 anterior/posterior pattern formation
1.36 2.02e-04 GO:0048646 anatomical structure formation involved in morphogenesis
1.15 2.13e-04 GO:0051252 regulation of RNA metabolic process
1.34 2.68e-04 GO:0048858 cell projection morphogenesis
1.26 2.71e-04 GO:0016265 death
1.34 2.78e-04 GO:0007417 central nervous system development
1.26 3.20e-04 GO:0008219 cell death
1.12 3.32e-04 GO:0071840 cellular component organization or biogenesis
1.43 3.65e-04 GO:0060284 regulation of cell development
1.34 3.78e-04 GO:0032990 cell part morphogenesis
1.15 3.83e-04 GO:0006355 regulation of transcription, DNA-dependent
1.43 4.01e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.08 5.00e-04 GO:0044237 cellular metabolic process
1.44 6.32e-04 GO:0001944 vasculature development
1.48 7.08e-04 GO:0048568 embryonic organ development
1.77 7.33e-04 GO:0030326 embryonic limb morphogenesis
1.77 7.33e-04 GO:0035113 embryonic appendage morphogenesis
1.89 7.61e-04 GO:0009953 dorsal/ventral pattern formation
1.13 1.43e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.12 2.29e-03 GO:0019538 protein metabolic process
1.26 3.42e-03 GO:0019220 regulation of phosphate metabolic process
1.26 3.42e-03 GO:0051174 regulation of phosphorus metabolic process
1.49 3.74e-03 GO:0044087 regulation of cellular component biogenesis
1.33 3.97e-03 GO:0051094 positive regulation of developmental process
1.32 4.03e-03 GO:0072358 cardiovascular system development
1.32 4.03e-03 GO:0072359 circulatory system development
1.38 4.08e-03 GO:0045597 positive regulation of cell differentiation
1.21 4.51e-03 GO:0010646 regulation of cell communication
1.67 4.76e-03 GO:0035107 appendage morphogenesis
1.67 4.76e-03 GO:0035108 limb morphogenesis
1.41 4.82e-03 GO:0061061 muscle structure development
1.25 5.11e-03 GO:0006915 apoptosis
1.50 5.49e-03 GO:0035239 tube morphogenesis
1.69 5.63e-03 GO:0003007 heart morphogenesis
1.37 5.70e-03 GO:0007411 axon guidance
1.49 5.85e-03 GO:0048732 gland development
1.33 6.23e-03 GO:0032583 regulation of gene-specific transcription
1.55 6.31e-03 GO:0060562 epithelial tube morphogenesis
1.13 6.34e-03 GO:0044267 cellular protein metabolic process
1.45 6.34e-03 GO:0051129 negative regulation of cellular component organization
1.43 6.45e-03 GO:0000165 MAPKKK cascade
1.35 7.63e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.45 7.63e-03 GO:0002009 morphogenesis of an epithelium
1.15 1.03e-02 GO:0043412 macromolecule modification
1.55 1.08e-02 GO:0001655 urogenital system development
1.25 1.08e-02 GO:0042325 regulation of phosphorylation
1.22 1.10e-02 GO:0009888 tissue development
1.63 1.11e-02 GO:0048736 appendage development
1.63 1.11e-02 GO:0060173 limb development
1.24 1.12e-02 GO:0012501 programmed cell death
1.20 1.22e-02 GO:0010941 regulation of cell death
1.20 1.31e-02 GO:0032268 regulation of cellular protein metabolic process
1.38 1.69e-02 GO:0030029 actin filament-based process
1.62 1.71e-02 GO:0072001 renal system development
1.20 1.79e-02 GO:0043067 regulation of programmed cell death
1.41 2.10e-02 GO:0030036 actin cytoskeleton organization
1.17 2.12e-02 GO:0035556 intracellular signal transduction
1.15 2.19e-02 GO:0009059 macromolecule biosynthetic process
1.71 2.39e-02 GO:0048706 embryonic skeletal system development
1.22 2.44e-02 GO:0031399 regulation of protein modification process
1.14 2.85e-02 GO:0010467 gene expression
1.15 2.96e-02 GO:0034645 cellular macromolecule biosynthetic process
1.35 3.03e-02 GO:0001501 skeletal system development
1.55 3.04e-02 GO:0048705 skeletal system morphogenesis
1.45 3.04e-02 GO:0007517 muscle organ development
1.56 3.30e-02 GO:0022604 regulation of cell morphogenesis
1.15 3.34e-02 GO:0016070 RNA metabolic process
1.25 3.42e-02 GO:0001932 regulation of protein phosphorylation
1.19 3.54e-02 GO:0007154 cell communication
1.19 3.98e-02 GO:0051246 regulation of protein metabolic process
1.19 4.47e-02 GO:0042981 regulation of apoptosis
1.42 4.52e-02 GO:0048514 blood vessel morphogenesis
1.60 4.92e-02 GO:0001822 kidney development
1.43 4.97e-02 GO:0001701 in utero embryonic development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.06 1.31e-10 GO:0044424 intracellular part
1.05 1.38e-08 GO:0005622 intracellular
1.07 5.31e-08 GO:0005737 cytoplasm
1.44 2.24e-07 GO:0043005 neuron projection
1.06 1.48e-06 GO:0043226 organelle
1.06 2.33e-06 GO:0043229 intracellular organelle
1.13 6.72e-05 GO:0043234 protein complex
1.73 9.16e-05 GO:0005925 focal adhesion
1.47 9.96e-05 GO:0016323 basolateral plasma membrane
1.54 1.00e-04 GO:0030424 axon
1.69 1.27e-04 GO:0030055 cell-substrate junction
1.70 1.40e-04 GO:0005924 cell-substrate adherens junction
1.15 1.43e-04 GO:0005829 cytosol
1.06 1.61e-04 GO:0043227 membrane-bounded organelle
1.06 1.84e-04 GO:0043231 intracellular membrane-bounded organelle
1.02 2.57e-04 GO:0044464 cell part
1.02 2.79e-04 GO:0005623 cell
1.24 3.04e-04 GO:0031982 vesicle
1.25 3.67e-04 GO:0031410 cytoplasmic vesicle
1.08 6.35e-04 GO:0005634 nucleus
1.55 7.26e-04 GO:0005912 adherens junction
1.27 8.97e-04 GO:0030054 cell junction
1.18 1.17e-03 GO:0005654 nucleoplasm
1.15 1.46e-03 GO:0031981 nuclear lumen
1.32 1.57e-03 GO:0045202 synapse
1.13 1.69e-03 GO:0044459 plasma membrane part
1.23 2.48e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.23 2.61e-03 GO:0031988 membrane-bounded vesicle
1.07 4.22e-03 GO:0044444 cytoplasmic part
1.20 6.90e-03 GO:0042995 cell projection
1.22 6.98e-03 GO:0044451 nucleoplasm part
1.47 7.55e-03 GO:0070161 anchoring junction
1.14 2.04e-02 GO:0005856 cytoskeleton
1.09 3.43e-02 GO:0032991 macromolecular complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 2.15e-20 GO:0005515 protein binding
1.44 2.31e-13 GO:0043565 sequence-specific DNA binding
1.06 1.82e-11 GO:0005488 binding
1.33 2.86e-11 GO:0001071 nucleic acid binding transcription factor activity
1.33 2.86e-11 GO:0003700 sequence-specific DNA binding transcription factor activity
1.31 1.90e-09 GO:0030528 transcription regulator activity
1.47 5.95e-06 GO:0008134 transcription factor binding
1.42 3.58e-05 GO:0003779 actin binding
1.39 5.36e-05 GO:0000988 protein binding transcription factor activity
1.39 5.36e-05 GO:0000989 transcription factor binding transcription factor activity
1.38 7.53e-05 GO:0003712 transcription cofactor activity
1.31 2.71e-04 GO:0008092 cytoskeletal protein binding
1.51 2.90e-04 GO:0010843 promoter binding
1.49 4.30e-04 GO:0000975 regulatory region DNA binding
1.49 4.30e-04 GO:0001067 regulatory region nucleic acid binding
1.49 4.30e-04 GO:0044212 transcription regulatory region DNA binding
1.24 2.23e-03 GO:0019899 enzyme binding
1.62 9.45e-03 GO:0051427 hormone receptor binding
1.20 1.04e-02 GO:0030234 enzyme regulator activity
1.33 2.47e-02 GO:0016564 transcription repressor activity
1.27 3.89e-02 GO:0019904 protein domain specific binding