Motif ID: NFE2L2.p2

Z-value: 3.489


Transcription factors associated with NFE2L2.p2:

Gene SymbolEntrez IDGene Name
NFE2L2 4780 nuclear factor (erythroid-derived 2)-like 2



Activity profile for motif NFE2L2.p2.

activity profile for motif NFE2L2.p2


Sorted Z-values histogram for motif NFE2L2.p2

Sorted Z-values for motif NFE2L2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_54350457 8.405 NM_002152
HRC
histidine rich calcium binding protein
chr10_-_76538859 7.796 NM_001007271
NM_001007272
NM_001007273
DUSP13


dual specificity phosphatase 13


chr16_-_28528149 6.690 NM_177530
NM_177534
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr19_-_53914768 6.164 NM_001130915
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr4_-_977163 5.858 NM_022042
NM_134425
NM_213613
SLC26A1


solute carrier family 26 (sulfate transporter), member 1


chr12_+_54361685 5.734 METTL7B
methyltransferase like 7B
chr22_+_43451600 5.684 PRR5
proline rich 5 (renal)
chr16_-_28528780 5.532 NM_001055
NM_177529
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr12_+_54361596 5.445 NM_152637
METTL7B
methyltransferase like 7B
chrX_-_100527799 5.010 NM_000061
BTK
Bruton agammaglobulinemia tyrosine kinase
chr16_-_28515195 4.964 NM_177528
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr17_+_72883759 4.821 NM_001113494
SEPT9
septin 9
chr16_+_29984611 4.517 ALDOA
aldolase A, fructose-bisphosphate
chr22_+_43451351 4.382 NM_001017530
NM_001198721
NM_015366
PRR5


proline rich 5 (renal)


chr16_+_29984591 4.329 ALDOA
aldolase A, fructose-bisphosphate
chr16_+_29984621 4.209 ALDOA
aldolase A, fructose-bisphosphate
chr16_+_29984544 4.045 NM_184041
ALDOA
aldolase A, fructose-bisphosphate
chr16_+_29984647 3.927 ALDOA
aldolase A, fructose-bisphosphate
chr7_+_139175420 3.881 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr6_-_31853027 3.878 NM_025258
C6orf27
chromosome 6 open reading frame 27
chr9_-_126309510 3.750 NM_004959
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr22_+_21393107 3.748 IGLJ3
immunoglobulin lambda joining 3
chr22_-_39189369 3.740 MKL1
megakaryoblastic leukemia (translocation) 1
chr15_+_57691382 3.737 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr22_+_20316968 3.683 NM_152612
CCDC116
coiled-coil domain containing 116
chr20_+_41621119 3.669 SGK2
serum/glucocorticoid regulated kinase 2
chr15_+_57691272 3.647 NM_004751
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr20_+_41621079 3.536 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr22_+_21340757 3.429


chr6_-_31812049 3.374 CLIC1
chloride intracellular channel 1
chr19_+_55398680 3.173 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr1_+_153232685 3.131 NM_018655
LENEP
lens epithelial protein
chr7_+_37926943 3.129 EPDR1
ependymin related protein 1 (zebrafish)
chr7_+_72883128 3.121 NM_001305
CLDN4
claudin 4
chr11_+_72660894 3.074 NM_004154
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr6_+_32003380 3.017 C2
complement component 2
chr22_+_21094094 3.005


chr6_+_150112537 2.989 PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr22_+_21370394 2.898 IGL@
immunoglobulin lambda locus
chr7_-_100667750 2.814 NM_014343
CLDN15
claudin 15
chr16_-_66075216 2.775 NM_001138
AGRP
agouti related protein homolog (mouse)
chr1_-_156923111 2.751 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr16_-_4778317 2.714 NM_001154458
NM_144605
SEPT12

septin 12

chr6_-_31812072 2.710 CLIC1
chloride intracellular channel 1
chr22_+_21484240 2.690


chr17_+_71109734 2.677 MYO15B
myosin XVB pseudogene
chr22_+_20899155 2.664


chr9_-_139042526 2.609 NM_001606
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr16_+_28413421 2.578 NM_018690
APOBR
apolipoprotein B receptor
chr17_+_77910411 2.559 NM_207459
TEX19
testis expressed 19
chr1_-_24307514 2.536 MYOM3
myomesin family, member 3
chr4_+_22608252 2.532


chr9_-_115880372 2.486 AMBP
alpha-1-microglobulin/bikunin precursor
chr3_-_180460372 2.473 NM_171829
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr6_+_150112511 2.467 NM_005389
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chrX_+_9391314 2.467 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr9_-_139042416 2.465 ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr14_-_22658078 2.464 NM_001805
CEBPE
CCAAT/enhancer binding protein (C/EBP), epsilon
chr19_-_40696393 2.460 NM_001126056
NM_001126057
NM_001126058
NM_001190347
NM_001190348
NM_001190349
NM_033317
DMKN






dermokine






chr22_+_21079355 2.459


chr6_-_31812251 2.452 CLIC1
chloride intracellular channel 1
chr21_-_35181956 2.451 RUNX1
runt-related transcription factor 1
chr22_+_21053972 2.447


chr6_-_31812260 2.429 CLIC1
chloride intracellular channel 1
chr22_-_25344037 2.404 CRYBB1
crystallin, beta B1
chrX_+_153423652 2.384 NM_001099856
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr6_-_31812283 2.379 CLIC1
chloride intracellular channel 1
chr16_-_30032330 2.371 NM_024307
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr3_+_122794859 2.358 NM_016298
FBXO40
F-box protein 40
chr6_-_31812266 2.350 CLIC1
chloride intracellular channel 1
chr6_-_31812214 2.346 CLIC1
chloride intracellular channel 1
chr11_+_118463906 2.317 NM_001024382
HMBS
hydroxymethylbilane synthase
chr6_-_31812297 2.301 NM_001288
CLIC1
chloride intracellular channel 1
chr22_-_25343959 2.279 NM_001887
CRYBB1
crystallin, beta B1
chr20_-_581844 2.272 NM_080725
SRXN1
sulfiredoxin 1
chr17_-_53764867 2.265


chr19_-_6621078 2.244 TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr3_-_121884091 2.239 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr10_+_134751398 2.239 NM_001083909
GPR123
G protein-coupled receptor 123
chr2_-_70901186 2.227 NM_173535
CLEC4F
C-type lectin domain family 4, member F
chr6_-_32121784 2.215 NM_032470
TNXB
tenascin XB
chr22_+_19699441 2.205 NM_001159554
NM_005446
P2RX6

purinergic receptor P2X, ligand-gated ion channel, 6

chr2_+_87536174 2.200 NCRNA00152
non-protein coding RNA 152
chr5_+_140594121 2.198 PCDHB18
protocadherin beta 18 pseudogene
chr2_+_87536106 2.143 NCRNA00152
non-protein coding RNA 152
chr3_-_121883647 2.126 HGD
homogentisate 1,2-dioxygenase
chr18_+_148480 2.122 NM_001037334
NM_005151
USP14

ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)

chr1_-_176205672 2.098 NM_033127
SEC16B
SEC16 homolog B (S. cerevisiae)
chr16_+_30903963 2.093 NM_001142777
NM_001142778
NM_025193
HSD3B7


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7


chrX_-_154216929 2.073 NM_001289
CLIC2
chloride intracellular channel 2
chr19_-_6621598 2.048 NM_003807
NM_172014
TNFSF14

tumor necrosis factor (ligand) superfamily, member 14

chr6_+_150112549 2.044 PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr22_+_21359175 2.036 IGLV3-25
immunoglobulin lambda variable 3-25
chr2_+_27358800 2.014 NM_032546
NM_187841
TRIM54

tripartite motif containing 54

chr11_+_62405736 2.011 SLC3A2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr20_+_48240705 2.009 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr20_+_34937928 2.008 NM_080628
C20orf118
chromosome 20 open reading frame 118
chr1_-_93030538 2.004 NM_005665
EVI5
ecotropic viral integration site 5
chr4_-_40212670 1.989 NM_019027
RBM47
RNA binding motif protein 47
chr22_+_21042091 1.985 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr22_+_21495273 1.977


chrX_-_152863251 1.974 NM_002910
RENBP
renin binding protein
chr6_+_64289585 1.966 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr5_+_179180447 1.950 NM_003900
SQSTM1
sequestosome 1
chr7_-_150352484 1.950 NM_173681
ATG9B
ATG9 autophagy related 9 homolog B (S. cerevisiae)
chr19_-_43926953 1.935 NM_144691
CAPN12
calpain 12
chr1_+_26220852 1.905 NM_004455
EXTL1
exostoses (multiple)-like 1
chr14_-_23847024 1.900 CIDEB
cell death-inducing DFFA-like effector b
chr20_+_61337679 1.889 NM_022161
NM_139317
BIRC7

baculoviral IAP repeat containing 7

chr1_-_45045543 1.887 NM_001013632
TCTEX1D4
Tctex1 domain containing 4
chr5_+_179180509 1.887 SQSTM1
sequestosome 1
chr9_+_139041736 1.886 NM_207511
C9orf139
chromosome 9 open reading frame 139
chr6_+_44322831 1.869 HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr6_-_30792830 1.868 MDC1
mediator of DNA-damage checkpoint 1
chr1_-_6585268 1.868 KLHL21
kelch-like 21 (Drosophila)
chr1_-_176205970 1.864 SEC16B
SEC16 homolog B (S. cerevisiae)
chr10_+_114126004 1.853 ACSL5
acyl-CoA synthetase long-chain family member 5
chr17_+_27795635 1.838 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr9_-_115880425 1.831 AMBP
alpha-1-microglobulin/bikunin precursor
chr5_+_179180517 1.831 SQSTM1
sequestosome 1
chr14_+_102672745 1.810 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr16_+_51690564 1.790 CHD9
chromodomain helicase DNA binding protein 9
chr20_+_48240867 1.778 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr14_-_23846904 1.777 CIDEB
cell death-inducing DFFA-like effector b
chr20_-_43889339 1.768 NM_003279
TNNC2
troponin C type 2 (fast)
chr9_-_122728173 1.756 TRAF1
TNF receptor-associated factor 1
chr20_+_48240772 1.742 NM_005194
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr16_+_30876115 1.742 NM_014712
SETD1A
SET domain containing 1A
chr4_-_80548378 1.730 NM_033214
GK2
glycerol kinase 2
chr9_-_115880281 1.720 AMBP
alpha-1-microglobulin/bikunin precursor
chr9_-_115880494 1.715 NM_001633
AMBP
alpha-1-microglobulin/bikunin precursor
chr9_-_115880366 1.713 AMBP
alpha-1-microglobulin/bikunin precursor
chr1_+_26220895 1.707 EXTL1
exostoses (multiple)-like 1
chr13_+_112746908 1.695 MCF2L
MCF.2 cell line derived transforming sequence-like
chr1_-_94147574 1.652 NM_002061
GCLM
glutamate-cysteine ligase, modifier subunit
chr3_-_39209075 1.634 NM_194293
NM_001198621
XIRP1

xin actin-binding repeat containing 1

chr6_+_44322764 1.632 NM_007355
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr7_+_111850367 1.631 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr12_+_100512877 1.629 NM_002465
NM_206819
NM_206820
NM_206821
MYBPC1



myosin binding protein C, slow type



chr11_+_123600553 1.623 NM_001007249
OR8G2
olfactory receptor, family 8, subfamily G, member 2
chrX_-_70243362 1.623 NM_001025265
CXorf65
chromosome X open reading frame 65
chr22_+_21407066 1.617


chr1_-_94147537 1.617 GCLM
glutamate-cysteine ligase, modifier subunit
chr22_+_21116283 1.615


chr2_-_61618165 1.614 XPO1
exportin 1 (CRM1 homolog, yeast)
chr5_+_132237253 1.612 NM_052971
LEAP2
liver expressed antimicrobial peptide 2
chr2_-_99238001 1.611 NM_175735
LYG2
lysozyme G-like 2
chr12_+_54910767 1.607 NM_001135195
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr19_-_61039939 1.604 NM_145007
NLRP11
NLR family, pyrin domain containing 11
chr1_-_7923464 1.588 NM_001561
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr1_-_158815850 1.556 CD84
CD84 molecule
chr2_-_190635566 1.555 NM_005259
MSTN
myostatin
chr7_-_75280962 1.554 NM_002991
CCL24
chemokine (C-C motif) ligand 24
chr1_-_6585485 1.550 NM_014851
KLHL21
kelch-like 21 (Drosophila)
chr10_-_99521701 1.546 NM_003015
SFRP5
secreted frizzled-related protein 5
chr2_-_219881937 1.544 PTPRN
protein tyrosine phosphatase, receptor type, N
chr17_-_35975227 1.529 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr1_+_17507276 1.502 NM_012387
PADI4
peptidyl arginine deiminase, type IV
chr11_+_10434056 1.493 NM_001025390
AMPD3
adenosine monophosphate deaminase 3
chr1_-_94147616 1.487 GCLM
glutamate-cysteine ligase, modifier subunit
chr2_-_233349469 1.486 NM_001172416
NM_001172417
NM_002242
KCNJ13


potassium inwardly-rectifying channel, subfamily J, member 13


chr6_-_30793436 1.482 NM_014641
MDC1
mediator of DNA-damage checkpoint 1
chr1_-_159543847 1.473 MPZ
myelin protein zero
chr11_+_5916033 1.471


chr6_-_35996794 1.465 SRPK1
SRSF protein kinase 1
chr12_-_101835026 1.461 PAH
phenylalanine hydroxylase
chr2_+_231629869 1.445 PSMD1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr7_+_150319076 1.415 NM_000603
NOS3
nitric oxide synthase 3 (endothelial cell)
chr14_-_106282128 1.413 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr10_+_685887 1.411 C10orf108
chromosome 10 open reading frame 108
chr22_+_18388656 1.399 C22orf25
chromosome 22 open reading frame 25
chr17_+_27795607 1.389 NM_002815
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr2_+_161873031 1.388 NM_005805
PSMD14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr22_+_21065134 1.383 LOC100290481
immunoglobulin lambda light chain-like
chr22_+_21065202 1.379


chr18_+_148586 1.375 USP14
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
chr16_+_2023279 1.367 SLC9A3R2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr6_+_32003180 1.365 NM_000063
NM_001145903
C2

complement component 2

chr19_+_61039755 1.361 NM_134444
NLRP4
NLR family, pyrin domain containing 4
chr22_+_21065207 1.359 IGLJ3
immunoglobulin lambda joining 3
chr1_-_199259133 1.359 KIF21B
kinesin family member 21B
chr19_-_56260135 1.357 NM_015596
KLK13
kallikrein-related peptidase 13
chr17_+_27795633 1.357 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr19_+_56319948 1.353 NM_001198558
NM_014441
SIGLEC9

sialic acid binding Ig-like lectin 9

chr9_-_99974994 1.345 NM_003389
CORO2A
coronin, actin binding protein, 2A
chr17_-_71287417 1.334 NM_005324
H3F3B
H3 histone, family 3B (H3.3B)
chr17_+_27795632 1.330 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr17_+_27795598 1.329 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr16_-_1369613 1.324 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr3_-_52844274 1.313 NM_205853
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr2_+_11597530 1.293 NM_148903
GREB1
growth regulation by estrogen in breast cancer 1
chr3_+_142525744 1.282 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr6_-_21631992 1.254


chr2_+_74635019 1.247 NM_001381
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr5_+_143171918 1.241 NM_021182
HMHB1
histocompatibility (minor) HB-1
chr22_-_17846725 1.234 NM_001035247
NM_005659
UFD1L

ubiquitin fusion degradation 1 like (yeast)

chr11_+_74548472 1.234 NM_001145211
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr5_+_61750467 1.216 NM_001134779
IPO11
importin 11
chr6_+_32229599 1.214 NM_005155
PPT2-EGFL8
PPT2
PPT2-EGFL8 read-through transcript
palmitoyl-protein thioesterase 2
chr6_+_32229278 1.213 NM_138717
PPT2
palmitoyl-protein thioesterase 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
5.66 1.18e-07 GO:0051351 positive regulation of ligase activity
7.09 1.60e-07 GO:0006521 regulation of cellular amino acid metabolic process
6.53 2.13e-07 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
6.53 2.13e-07 GO:0072395 signal transduction involved in cell cycle checkpoint
6.53 2.13e-07 GO:0072401 signal transduction involved in DNA integrity checkpoint
6.53 2.13e-07 GO:0072404 signal transduction involved in G1/S transition checkpoint
6.53 2.13e-07 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
6.53 2.13e-07 GO:0072422 signal transduction involved in DNA damage checkpoint
6.53 2.13e-07 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
6.53 2.13e-07 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
5.92 4.23e-07 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
6.22 5.14e-07 GO:0071158 positive regulation of cell cycle arrest
5.85 1.53e-06 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
4.94 1.84e-06 GO:0051340 regulation of ligase activity
5.46 1.92e-06 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
5.39 2.43e-06 GO:0051443 positive regulation of ubiquitin-protein ligase activity
4.59 3.25e-06 GO:0000077 DNA damage checkpoint
5.25 3.85e-06 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
5.87 4.27e-06 GO:0033238 regulation of cellular amine metabolic process
5.12 6.01e-06 GO:2000045 regulation of G1/S transition of mitotic cell cycle
4.31 1.15e-05 GO:0031570 DNA integrity checkpoint
3.73 1.17e-05 GO:0010498 proteasomal protein catabolic process
3.73 1.17e-05 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
5.10 1.67e-05 GO:0000216 M/G1 transition of mitotic cell cycle
5.10 1.67e-05 GO:0031575 mitotic cell cycle G1/S transition checkpoint
5.10 1.67e-05 GO:0071779 G1/S transition checkpoint
4.67 3.11e-05 GO:0051438 regulation of ubiquitin-protein ligase activity
5.28 6.63e-05 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
4.63 8.51e-05 GO:0030330 DNA damage response, signal transduction by p53 class mediator
2.67 1.12e-04 GO:0051603 proteolysis involved in cellular protein catabolic process
4.13 1.15e-04 GO:0042770 signal transduction in response to DNA damage
5.06 1.29e-04 GO:0051352 negative regulation of ligase activity
5.06 1.29e-04 GO:0051444 negative regulation of ubiquitin-protein ligase activity
2.61 1.85e-04 GO:0044257 cellular protein catabolic process
4.00 4.18e-04 GO:0090068 positive regulation of cell cycle process
1.94 5.17e-04 GO:0006508 proteolysis
2.59 5.20e-04 GO:0019941 modification-dependent protein catabolic process
2.57 6.11e-04 GO:0043632 modification-dependent macromolecule catabolic process
3.89 6.61e-04 GO:0000084 S phase of mitotic cell cycle
3.89 6.61e-04 GO:0031398 positive regulation of protein ubiquitination
3.82 8.89e-04 GO:0051320 S phase
2.57 9.43e-04 GO:0006511 ubiquitin-dependent protein catabolic process
2.44 1.03e-03 GO:0030163 protein catabolic process
4.07 2.99e-03 GO:0031397 negative regulation of protein ubiquitination
3.33 4.33e-03 GO:0010565 regulation of cellular ketone metabolic process
1.70 4.74e-03 GO:0044248 cellular catabolic process
3.39 5.80e-03 GO:0007093 mitotic cell cycle checkpoint
3.14 1.08e-02 GO:0031396 regulation of protein ubiquitination
1.84 2.24e-02 GO:0006915 apoptosis
1.56 2.93e-02 GO:0009056 catabolic process
1.82 3.45e-02 GO:0012501 programmed cell death
2.60 3.51e-02 GO:0000075 cell cycle checkpoint
1.66 4.33e-02 GO:0042981 regulation of apoptosis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
7.37 6.88e-11 GO:0000502 proteasome complex
8.85 4.29e-04 GO:0005839 proteasome core complex
1.16 1.06e-02 GO:0005737 cytoplasm
1.39 3.81e-02 GO:0005829 cytosol

Gene overrepresentation in function category:

enrichment   p-value GO term description
8.42 9.36e-04 GO:0004298 threonine-type endopeptidase activity
8.42 9.36e-04 GO:0070003 threonine-type peptidase activity
4.98 2.69e-02 GO:0003823 antigen binding