Motif ID: NFIL3.p2

Z-value: 0.988


Transcription factors associated with NFIL3.p2:

Gene SymbolEntrez IDGene Name
NFIL3 4783 nuclear factor, interleukin 3 regulated



Activity profile for motif NFIL3.p2.

activity profile for motif NFIL3.p2


Sorted Z-values histogram for motif NFIL3.p2

Sorted Z-values for motif NFIL3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIL3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_70567634 2.782 SULF1
sulfatase 1
chr22_-_34564611 2.542 RPL41P5
ribosomal protein L41 pseudogene 5
chr8_+_70567581 2.101 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr1_+_194887630 2.090 NM_000186
NM_001014975
CFH

complement factor H

chrX_-_33139349 1.975 NM_004006
DMD
dystrophin
chr3_-_159872960 1.590 NM_020169
LXN
latexin
chr4_-_74307637 1.344 ANKRD17
ankyrin repeat domain 17
chr4_+_74921136 1.334 NM_002993
CXCL6
chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
chr5_-_94442941 1.334 MCTP1
multiple C2 domains, transmembrane 1
chr20_-_55718982 1.254 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1

chr5_-_94443300 1.206 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr5_+_36642213 1.150 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr14_+_95792299 1.137 NM_000710
BDKRB1
bradykinin receptor B1
chr4_+_3341521 1.097 NM_198227
RGS12
regulator of G-protein signaling 12
chr5_+_36642424 1.056 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_-_31491102 1.028 NM_000379
XDH
xanthine dehydrogenase
chr5_+_56507029 0.966 NM_001127235
GPBP1
GC-rich promoter binding protein 1
chr2_-_31491057 0.937 XDH
xanthine dehydrogenase
chr1_+_65503011 0.917 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr8_+_94999167 0.894 NM_001161778
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr3_-_113842652 0.891 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr15_-_63871492 0.883 DENND4A
DENN/MADD domain containing 4A
chr17_-_26665144 0.850 EVI2B
ecotropic viral integration site 2B
chr7_+_134114701 0.840 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr13_+_28900776 0.834 NM_015233
MTUS2
microtubule associated tumor suppressor candidate 2
chr12_-_44407515 0.831 LOC400027
hypothetical LOC400027
chr4_+_88187215 0.829 AFF1
AF4/FMR2 family, member 1
chr10_+_135190855 0.808 NM_000773
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr17_+_36493927 0.805 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr8_-_130868315 0.790 NM_031415
GSDMC
gasdermin C
chr4_-_77147625 0.782 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr17_+_36515166 0.747 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chrX_+_56772391 0.733 LOC550643
hypothetical LOC550643
chr11_+_93394025 0.721 NM_001098672
HEPHL1
hephaestin-like 1
chr1_-_177378801 0.711 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr17_-_36528113 0.697 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr4_+_146820805 0.696 NM_001080531
C4orf51
chromosome 4 open reading frame 51
chr4_-_96689373 0.695 NM_003728
UNC5C
unc-5 homolog C (C. elegans)
chr9_+_17568952 0.692 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr10_+_50557689 0.686 NM_001042427
NM_182554
C10orf53

chromosome 10 open reading frame 53

chr2_-_213723298 0.686 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr9_+_27514311 0.674 NM_020124
IFNK
interferon, kappa
chr3_+_62280435 0.673 NM_020685
C3orf14
chromosome 3 open reading frame 14
chr13_-_37070862 0.671 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr1_-_109957195 0.636 NM_005272
GNAT2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr20_+_33223434 0.634 NM_006404
PROCR
protein C receptor, endothelial
chr13_+_96672705 0.632 MBNL2
muscleblind-like 2 (Drosophila)
chr17_-_59204622 0.627 CCDC47
coiled-coil domain containing 47
chr12_-_123568781 0.619


chr3_+_130014957 0.619 RAB7A
RAB7A, member RAS oncogene family
chr1_+_86785346 0.607 NM_012128
CLCA4
chloride channel accessory 4
chr1_+_176577228 0.605 NM_004841
RASAL2
RAS protein activator like 2
chr6_-_28429950 0.603 NM_145909
ZNF323
zinc finger protein 323
chr22_+_39817733 0.597 EP300
E1A binding protein p300
chr1_-_151614681 0.591 NM_005621
S100A12
S100 calcium binding protein A12
chr3_+_44667504 0.585 ZNF35
zinc finger protein 35
chr12_-_44407756 0.585 LOC400027
hypothetical LOC400027
chr1_+_161305188 0.576 NM_005613
RGS4
regulator of G-protein signaling 4
chr4_+_110574376 0.573 NM_001042734
NM_006323
SEC24B

SEC24 family, member B (S. cerevisiae)

chr17_-_59204685 0.572 NM_020198
CCDC47
coiled-coil domain containing 47
chr8_-_102286695 0.558 ZNF706
zinc finger protein 706
chr5_-_38592439 0.558 NM_001127671
LIFR
leukemia inhibitory factor receptor alpha
chr15_-_53996597 0.547 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr1_-_42157077 0.532 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr4_+_110574420 0.527 SEC24B
SEC24 family, member B (S. cerevisiae)
chr2_-_63518589 0.523 NM_001042692
WDPCP
WD repeat containing planar cell polarity effector
chr12_-_116283793 0.521 NM_000620
NOS1
nitric oxide synthase 1 (neuronal)
chr1_+_11171967 0.509 NM_021146
ANGPTL7
angiopoietin-like 7
chr4_-_110574363 0.501 1/2-SBSRNA4
lncRNA_BC009800
chr21_-_26345294 0.494


chr11_+_111552298 0.494 NM_001037290
BCO2
beta-carotene oxygenase 2
chr4_-_153820535 0.472 NM_152680
TMEM154
transmembrane protein 154
chr12_+_50633430 0.467 NM_020327
ACVR1B
activin A receptor, type IB
chr13_-_24644304 0.435 FAM123A
family with sequence similarity 123A
chr2_-_133145539 0.434 NM_001077427
LYPD1
LY6/PLAUR domain containing 1
chr3_+_156280604 0.432 NM_007288
MME
membrane metallo-endopeptidase
chr4_+_120167264 0.430 SYNPO2
synaptopodin 2
chr8_-_72436832 0.429 EYA1
eyes absent homolog 1 (Drosophila)
chrX_-_77037563 0.426 NM_032121
MAGT1
magnesium transporter 1
chr12_+_123339662 0.424 NM_181709
FAM101A
family with sequence similarity 101, member A
chr2_+_102294393 0.424 NM_016232
IL18R1
IL1RL1
interleukin 18 receptor 1
interleukin 1 receptor-like 1
chr2_-_133895795 0.415 NCKAP5
NCK-associated protein 5
chr8_-_110689396 0.414 SYBU
syntabulin (syntaxin-interacting)
chr4_+_119174947 0.410 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr8_-_17599438 0.397 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr5_-_52441044 0.396 NM_004531
MOCS2
molybdenum cofactor synthesis 2
chr13_-_43908937 0.395 TSC22D1
TSC22 domain family, member 1
chr7_-_112515068 0.389 NM_001146265
NM_018970
GPR85

G protein-coupled receptor 85

chr1_-_6218576 0.387 ICMT
isoprenylcysteine carboxyl methyltransferase
chr3_+_191588354 0.374 NM_006580
CLDN16
claudin 16
chr5_-_147996769 0.368 NM_001040169
NM_001040172
NM_001040173
NM_199453
HTR4



5-hydroxytryptamine (serotonin) receptor 4



chr7_+_28692122 0.364 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr9_+_71009746 0.363 NM_001170415
NM_001170416
TJP2

tight junction protein 2 (zona occludens 2)

chr18_-_35634247 0.357 LOC647946
hypothetical LOC647946
chr14_+_101345878 0.355 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr2_-_45648608 0.355 SRBD1
S1 RNA binding domain 1
chr6_+_7347878 0.354 NM_153005
RIOK1
RIO kinase 1 (yeast)
chr22_-_29197944 0.354 NM_174975
SEC14L3
SEC14-like 3 (S. cerevisiae)
chr13_+_113546943 0.344 GAS6
growth arrest-specific 6
chr3_+_152970904 0.344 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr6_-_2785682 0.343 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr19_+_46121963 0.340 CYP2B7P1
cytochrome P450, family 2, subfamily B, polypeptide 7 pseudogene 1
chr15_-_47042932 0.335 NM_203349
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr7_-_122627235 0.323 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr17_-_36559579 0.322 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr3_+_42107711 0.317 NM_001042646
TRAK1
trafficking protein, kinesin binding 1
chr11_+_5667494 0.315 NM_006074
TRIM22
tripartite motif containing 22
chr17_-_36074812 0.311 NM_152349
KRT222
keratin 222
chr9_-_98104206 0.306 NM_000197
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chr6_+_134800533 0.305 LOC154092
hypothetical LOC154092
chr9_-_32540818 0.304 TOPORS
topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
chr17_-_26672757 0.304 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr7_-_112515035 0.303 GPR85
G protein-coupled receptor 85
chr16_-_53520208 0.295 CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr1_-_171838802 0.294 NM_178527
SLC9A11
solute carrier family 9, member 11
chr5_-_79982584 0.293 NM_001190470
MTRNR2L2
MT-RNR2-like 2
chr8_+_69026895 0.292 PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr4_-_87989291 0.289 NM_197965
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr4_-_186815116 0.288 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr5_+_140235114 0.288 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr13_+_96672541 0.287 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr3_+_103029523 0.287 NM_001005474
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr22_+_25347927 0.285 NM_001886
CRYBA4
crystallin, beta A4
chr10_-_119795663 0.285 NM_014904
RAB11FIP2
RAB11 family interacting protein 2 (class I)
chr2_+_148319033 0.284 NM_001616
ACVR2A
activin A receptor, type IIA
chr3_+_156280539 0.283 MME
membrane metallo-endopeptidase
chr17_+_59205289 0.280 NM_007372
NM_203499
DDX42

DEAD (Asp-Glu-Ala-Asp) box polypeptide 42

chr7_-_142369519 0.280 KEL
Kell blood group, metallo-endopeptidase
chr4_-_159311959 0.278 FAM198B
family with sequence similarity 198, member B
chr1_-_6218554 0.275 ICMT
isoprenylcysteine carboxyl methyltransferase
chr10_+_68355797 0.274 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr10_+_91077581 0.273 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr14_+_93646831 0.269 NM_001130080
NM_005532
IFI27

interferon, alpha-inducible protein 27

chr12_-_69317441 0.268 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr1_+_144236346 0.265 NM_003637
ITGA10
integrin, alpha 10
chr6_-_136889302 0.265 MAP7
microtubule-associated protein 7
chr17_-_26665194 0.264 EVI2B
ecotropic viral integration site 2B
chr5_-_127901376 0.264 FBN2
fibrillin 2
chr9_+_674193 0.263


chr12_-_73889777 0.256 NM_139136
NM_139137
NM_153748
KCNC2


potassium voltage-gated channel, Shaw-related subfamily, member 2


chr7_+_150321771 0.255 NM_001160109
NM_001160110
NM_001160111
NOS3


nitric oxide synthase 3 (endothelial cell)


chr4_+_71713324 0.255 NM_031889
ENAM
enamelin
chrX_-_131919896 0.254 HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr6_+_153060722 0.254 NM_025107
MYCT1
myc target 1
chr13_+_110165329 0.251 NM_005537
ING1
inhibitor of growth family, member 1
chr13_-_79810972 0.250 SPRY2
sprouty homolog 2 (Drosophila)
chr2_-_192420168 0.246 NM_004657
SDPR
serum deprivation response
chr2_-_98646367 0.246 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr11_-_128399218 0.245 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr1_-_150599105 0.242 NM_001014342
FLG2
filaggrin family member 2
chr17_-_70901303 0.242 GRB2
growth factor receptor-bound protein 2
chr11_-_10487212 0.242 NM_001190702
MTRNR2L8
MT-RNR2-like 8
chr2_-_224611568 0.241 NM_001136530
SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr13_+_113546912 0.236 GAS6
growth arrest-specific 6
chr10_-_64698831 0.235 NM_004241
JMJD1C
jumonji domain containing 1C
chr7_-_142369534 0.235 NM_000420
KEL
Kell blood group, metallo-endopeptidase
chr7_-_141048358 0.232 NM_001080392
KIAA1147
KIAA1147
chr1_+_144236398 0.230 ITGA10
integrin, alpha 10
chr6_+_121798443 0.229 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr1_+_25629968 0.227 NM_018202
TMEM57
transmembrane protein 57
chr11_+_68818175 0.224 NM_138768
MYEOV
myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
chr1_-_242073094 0.223 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chr2_+_64540843 0.223 HSPC159
galectin-related protein
chr16_+_80086454 0.221 NM_030629
CMIP
c-Maf-inducing protein
chr4_+_111616630 0.219 NM_001977
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr13_-_28190961 0.219 NM_001135919
NM_181785
SLC46A3

solute carrier family 46, member 3

chr1_+_231007260 0.218 NM_019090
KIAA1383
KIAA1383
chr7_-_112513379 0.216 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr1_+_7767300 0.215 NM_016831
PER3
period homolog 3 (Drosophila)
chr4_-_153493133 0.214 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr14_+_19458580 0.213 NM_001005483
OR4K5
olfactory receptor, family 4, subfamily K, member 5
chr1_-_54183833 0.213 NM_016126
HSPB11
heat shock protein family B (small), member 11
chr11_+_4799126 0.210 NM_001004753
OR51F2
olfactory receptor, family 51, subfamily F, member 2
chr10_+_95838801 0.209 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr15_-_56145140 0.207 NM_003888
NM_170696
ALDH1A2

aldehyde dehydrogenase 1 family, member A2

chr10_+_63331018 0.207 NM_032199
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr6_+_50894397 0.205 NM_003221
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr17_-_26665220 0.203 NM_006495
EVI2B
ecotropic viral integration site 2B
chr17_-_64649608 0.200 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr1_+_231007734 0.197 KIAA1383
KIAA1383
chr2_+_160180049 0.197 LOC643072
hypothetical LOC643072
chr17_+_38250122 0.196 NM_001158
NM_009590
AOC2

amine oxidase, copper containing 2 (retina-specific)

chr16_-_31347151 0.196 NM_005205
COX6A2
cytochrome c oxidase subunit VIa polypeptide 2
chr2_+_113542017 0.196 NM_173161
IL1F10
interleukin 1 family, member 10 (theta)
chr17_-_46140015 0.196 NM_052855
ANKRD40
ankyrin repeat domain 40
chr12_-_16649211 0.195 LMO3
LIM domain only 3 (rhombotin-like 2)
chr19_+_46286207 0.195 NM_000766
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr12_-_7487989 0.195 NM_174941
CD163L1
CD163 molecule-like 1
chr4_+_141397889 0.194 NM_032547
SCOC
short coiled-coil protein
chr14_-_66896167 0.194 NM_015994
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr1_+_157246305 0.194 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr8_-_6407882 0.194 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr17_-_36436979 0.193 NM_031957
KRTAP1-5
keratin associated protein 1-5
chr10_-_102663070 0.192


chr7_-_44992729 0.191 C7orf40
chromosome 7 open reading frame 40
chr3_-_102194938 0.191 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr1_-_60312013 0.190 NM_152377
C1orf87
chromosome 1 open reading frame 87
chr1_-_154988045 0.189 HDGF
hepatoma-derived growth factor
chr12_-_51360439 0.189 NM_006121
KRT1
keratin 1
chr8_-_102287044 0.189 NM_001042511
ZNF706
zinc finger protein 706

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
29.63 1.90e-02 GO:0047023 androsterone dehydrogenase activity
29.63 1.90e-02 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity