Motif ID: NFKB1_REL_RELA.p2

Z-value: 3.802


Transcription factors associated with NFKB1_REL_RELA.p2:

Gene SymbolEntrez IDGene Name
NFKB1 4790 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
REL 5966 v-rel reticuloendotheliosis viral oncogene homolog (avian)
RELA 5970 v-rel reticuloendotheliosis viral oncogene homolog A (avian)



Activity profile for motif NFKB1_REL_RELA.p2.

activity profile for motif NFKB1_REL_RELA.p2


Sorted Z-values histogram for motif NFKB1_REL_RELA.p2

Sorted Z-values for motif NFKB1_REL_RELA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFKB1_REL_RELA.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_219453487 8.592 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr2_-_231498184 5.631 NM_005683
GPR55
G protein-coupled receptor 55
chr17_+_35277942 5.306 NM_198844
NM_199321
ZPBP2

zona pellucida binding protein 2

chr20_-_4743768 5.296 NM_170774
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr17_-_33178987 5.047 HNF1B
HNF1 homeobox B
chr19_+_4180494 4.969 NM_005755
EBI3
Epstein-Barr virus induced 3
chr9_+_126094067 4.602 NM_001166170
NM_001166171
NEK6

NIMA (never in mitosis gene a)-related kinase 6

chr14_-_95250155 4.435 NM_001098725
NM_021966
TCL1A

T-cell leukemia/lymphoma 1A

chr3_-_13089547 4.127 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr12_+_6925997 4.087 NM_080548
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr19_-_6542012 3.952 CD70
CD70 molecule
chr19_+_40632456 3.935 NM_005306
FFAR2
free fatty acid receptor 2
chr9_+_126094388 3.863 NM_001166169
NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr12_+_6926014 3.819 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr20_-_44370537 3.738 CDH22
cadherin 22, type 2
chr19_-_7672978 3.735 NM_002002
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr17_+_45993338 3.651 NM_018896
NM_198376
NM_198377
NM_198378
NM_198379
NM_198380
NM_198382
NM_198383
NM_198384
NM_198385
NM_198386
NM_198387
NM_198388
NM_198396
NM_198397
CACNA1G














calcium channel, voltage-dependent, T type, alpha 1G subunit














chr17_+_7402315 3.572 NM_001198622
NM_001198623
NM_001198624
NM_003808
NM_172087
NM_172088
TNFSF13





tumor necrosis factor (ligand) superfamily, member 13





chr15_+_79376295 3.378 NM_004513
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr17_+_22823151 3.366 NM_014238
KSR1
kinase suppressor of ras 1
chr15_-_38185578 3.344 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chr19_+_47073029 3.340 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr1_-_24386324 3.308 NM_170743
NM_173064
NM_173065
IL28RA


interleukin 28 receptor, alpha (interferon, lambda receptor)


chr6_+_32713160 3.271 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr3_+_123279439 3.208 NM_006889
CD86
CD86 molecule
chr1_+_6767968 3.197 NM_001195563
NM_015215
CAMTA1

calmodulin binding transcription activator 1

chr22_-_35875890 3.087 NM_000878
IL2RB
interleukin 2 receptor, beta
chr3_-_58175437 3.005 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr19_+_3087026 2.992 NM_002068
GNA15
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
chr1_+_26744929 2.916 NM_001006665
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr11_-_60880799 2.893 NM_001161452
CYBASC3
cytochrome b, ascorbate dependent 3
chr1_-_200397300 2.871 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr6_-_30188845 2.827 NM_007028
TRIM31
tripartite motif containing 31
chr3_-_113334657 2.827 NM_001190259
NM_001190260
NM_152785
GCET2


germinal center expressed transcript 2


chr17_-_16816113 2.823 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr2_-_74522563 2.795 NM_001015055
RTKN
rhotekin
chr1_+_26744893 2.786 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr17_-_33179118 2.722 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr14_-_69725342 2.703 NM_033262
NM_058240
NM_182932
NM_183002
SLC8A3



solute carrier family 8 (sodium/calcium exchanger), member 3



chr2_-_74522534 2.689 RTKN
rhotekin
chr6_+_31648071 2.680 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr2_-_74522513 2.677 RTKN
rhotekin
chr6_+_31647854 2.647 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr11_-_65070625 2.644 LTBP3
latent transforming growth factor beta binding protein 3
chr19_+_17499064 2.620 FAM129C
family with sequence similarity 129, member C
chr17_-_35506493 2.611 NR1D1
nuclear receptor subfamily 1, group D, member 1
chr17_-_31231421 2.584 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr6_+_30958672 2.573 DDR1
discoidin domain receptor tyrosine kinase 1
chr14_+_75058518 2.570 NM_006399
BATF
basic leucine zipper transcription factor, ATF-like
chr13_-_49597776 2.560 DLEU2
deleted in lymphocytic leukemia 2 (non-protein coding)
chr1_-_200395741 2.542 NM_080588
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr16_+_49288550 2.527 NM_022162
NOD2
nucleotide-binding oligomerization domain containing 2
chr5_-_149772528 2.517


chr7_-_44985084 2.471 MYO1G
myosin IG
chrX_-_30505804 2.464 NM_025159
CXorf21
chromosome X open reading frame 21
chr14_+_75058591 2.415 BATF
basic leucine zipper transcription factor, ATF-like
chr12_+_50731457 2.388 NM_002135
NM_173157
NR4A1

nuclear receptor subfamily 4, group A, member 1

chr1_+_67404756 2.386 NM_144701
IL23R
interleukin 23 receptor
chr18_-_6404900 2.385 NM_173464
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chrX_+_12795111 2.350 NM_016562
TLR7
toll-like receptor 7
chr14_-_23878871 2.321 NM_006871
RIPK3
receptor-interacting serine-threonine kinase 3
chr17_-_58877276 2.321 NM_001017916
NM_001915
CYB561

cytochrome b-561

chr1_-_159275334 2.311 TSTD1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr6_-_32659958 2.308 HLA-DRB1
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 5
chr1_-_207892420 2.307 NM_000228
LAMB3
laminin, beta 3
chr2_+_233633348 2.296 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr12_+_111980044 2.268 NM_004416
DTX1
deltex homolog 1 (Drosophila)
chr19_+_5082230 2.265 KDM4B
lysine (K)-specific demethylase 4B
chr1_+_25816545 2.242 NM_020379
MAN1C1
mannosidase, alpha, class 1C, member 1
chr19_-_48976852 2.226 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr2_+_68815416 2.223 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr5_-_149772469 2.200 NM_001025159
NM_004355
NM_001025158
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr2_+_233633279 2.193 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr12_-_53661888 2.176 NM_001098815
KIAA0748
KIAA0748
chr19_+_1018536 2.173 HMHA1
histocompatibility (minor) HA-1
chr11_+_66580884 2.158 RHOD
ras homolog gene family, member D
chr15_+_57517564 2.146 NM_152450
FAM81A
family with sequence similarity 81, member A
chr5_+_60663842 2.142 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr1_-_181826633 2.127 NM_001127651
NCF2
neutrophil cytosolic factor 2
chr19_-_48977247 2.122 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr19_-_6542082 2.119 CD70
CD70 molecule
chr17_+_37694007 2.110 STAT5A
signal transducer and activator of transcription 5A
chr2_+_237143118 2.105 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr6_-_27387989 2.101 NM_033482
POM121L2
POM121 membrane glycoprotein-like 2
chr17_+_8865547 2.082 NM_004822
NTN1
netrin 1
chr10_-_6144119 2.060 NM_000417
IL2RA
interleukin 2 receptor, alpha
chr20_+_44180296 2.051 NM_001250
NM_152854
CD40

CD40 molecule, TNF receptor superfamily member 5

chr17_-_71352182 2.043 NM_199242
UNC13D
unc-13 homolog D (C. elegans)
chr19_+_17723285 2.037 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr20_-_55628852 2.018 NM_001160417
NM_001160418
NM_001160419
NM_030776
ZBP1



Z-DNA binding protein 1



chr19_+_44697592 1.976 NM_182704
SELV
selenoprotein V
chr10_-_134940315 1.971 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr1_+_200246370 1.967 ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr6_-_29635456 1.966 UBD
ubiquitin D
chr19_-_47190160 1.946 NM_152296
ATP1A3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr12_+_47658502 1.942 NM_005430
WNT1
wingless-type MMTV integration site family, member 1
chr22_-_35970133 1.925 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr11_+_120828058 1.919 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr16_+_84490267 1.917 NM_002163
IRF8
interferon regulatory factor 8
chr11_+_66580861 1.915 NM_014578
RHOD
ras homolog gene family, member D
chr2_+_231968578 1.913 NM_145236
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr19_+_55614006 1.896 NM_003121
SPIB
Spi-B transcription factor (Spi-1/PU.1 related)
chr1_+_154389945 1.896 NM_001193300
NM_022367
NM_001193302
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr22_-_35970230 1.868 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr4_-_120768563 1.866 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr18_-_26996742 1.852 NM_004948
NM_024421
DSC1

desmocollin 1

chr9_-_139235595 1.849 NM_031297
RNF208
ring finger protein 208
chr1_-_159275357 1.832 NM_001113205
NM_001113206
NM_001113207
TSTD1


F11R
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1


F11 receptor
chr10_+_102746819 1.829 NM_032429
LZTS2
leucine zipper, putative tumor suppressor 2
chr5_+_177473071 1.824 NM_015111
N4BP3
NEDD4 binding protein 3
chr15_-_72804763 1.818 NM_000499
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr7_+_149042960 1.817 NM_032534
KRBA1
KRAB-A domain containing 1
chr1_-_200396354 1.816 NM_002832
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr1_+_154390939 1.814 SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr1_-_200396328 1.794 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr19_-_17819814 1.789 NM_000215
JAK3
Janus kinase 3
chr7_-_44985202 1.788 NM_033054
MYO1G
myosin IG
chr1_-_233879617 1.787 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr6_-_29635680 1.783 NM_006398
UBD
ubiquitin D
chr17_-_71352017 1.768 UNC13D
unc-13 homolog D (C. elegans)
chr6_+_14225932 1.765 CD83
CD83 molecule
chr5_-_149772563 1.754 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr19_-_17819773 1.754 JAK3
Janus kinase 3
chr19_-_4289750 1.739 NM_001013841
NM_017720
STAP2

signal transducing adaptor family member 2

chr8_-_70909754 1.739 NM_030958
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr13_-_45654327 1.724 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_199130571 1.709 NM_001142569
C1orf106
chromosome 1 open reading frame 106
chr1_-_205210567 1.708 NM_001122979
NM_001170631
NM_032029
FCAMR


Fc receptor, IgA, IgM, high affinity


chr16_+_66128843 1.705 NM_001193524
FAM65A
family with sequence similarity 65, member A
chr1_+_200246312 1.701 NM_001114309
NM_004433
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr5_+_176807931 1.692 NM_001174102
PRR7
proline rich 7 (synaptic)
chr11_+_118259684 1.690 NM_001716
CXCR5
chemokine (C-X-C motif) receptor 5
chr1_-_181826292 1.688 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr8_-_22606401 1.687 EGR3
early growth response 3
chr9_-_139068269 1.677 NM_001246
NM_203468
ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2

chr17_+_69974116 1.674 NM_007261
CD300A
CD300a molecule
chrX_+_78087484 1.668 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr19_+_8180179 1.623 NM_024552
LASS4
LAG1 homolog, ceramide synthase 4
chr8_-_11096257 1.605 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr8_+_144706699 1.602 NM_001166237
GSDMD
gasdermin D
chr7_-_44985175 1.588 MYO1G
myosin IG
chr12_-_28016182 1.571 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr9_+_139047441 1.571 C9orf139
chromosome 9 open reading frame 139
chr7_-_150737980 1.555 NM_198285
WDR86
WD repeat domain 86
chr14_-_50631407 1.552 TRIM9
tripartite motif containing 9
chr5_+_96319910 1.552 NM_175920
LNPEP
leucyl/cystinyl aminopeptidase
chr18_-_26935427 1.542 DSC2
desmocollin 2
chr3_+_113200696 1.541 NM_001008273
TAGLN3
transgelin 3
chr11_+_122031549 1.523 NM_032873
UBASH3B
ubiquitin associated and SH3 domain containing B
chr4_+_107036076 1.523 NPNT
nephronectin
chr8_-_11361594 1.504 NM_053279
FAM167A
family with sequence similarity 167, member A
chr16_-_55875953 1.502 PLLP
plasmolipin
chr4_-_13158391 1.491 LOC285548
hypothetical LOC285548
chr16_-_73798539 1.489 NM_001025200
CTRB1
CTRB2
chymotrypsinogen B1
chymotrypsinogen B2
chr17_+_45401560 1.459 NM_138281
DLX4
distal-less homeobox 4
chr11_-_133332089 1.454 NM_014987
IGSF9B
immunoglobulin superfamily, member 9B
chr17_+_7402788 1.451 TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr1_-_164402700 1.446 FAM78B
family with sequence similarity 78, member B
chr4_-_77163609 1.440 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr1_-_21489235 1.409 NM_001113349
ECE1
endothelin converting enzyme 1
chr19_-_11549441 1.404 ACP5
acid phosphatase 5, tartrate resistant
chr14_-_23106779 1.394 AP1G2
adaptor-related protein complex 1, gamma 2 subunit
chr22_+_38720881 1.393 NM_138435
FAM83F
family with sequence similarity 83, member F
chr16_-_55876075 1.391 NM_015993
PLLP
plasmolipin
chr9_-_135334003 1.383 NM_001145099
NM_017585
SLC2A6

solute carrier family 2 (facilitated glucose transporter), member 6

chr16_-_31135895 1.382 NM_152901
PYDC1
PYD (pyrin domain) containing 1
chr16_+_23221091 1.379 NM_000336
SCNN1B
sodium channel, nonvoltage-gated 1, beta
chr5_+_10617431 1.377 NM_001164440
ANKRD33B
ankyrin repeat domain 33B
chr7_+_68702516 1.377 AUTS2
autism susceptibility candidate 2
chr9_+_126579203 1.367 NM_182487
OLFML2A
olfactomedin-like 2A
chr16_-_55876099 1.352 PLLP
plasmolipin
chr1_-_153107084 1.349


chr19_+_10388448 1.345 PDE4A
phosphodiesterase 4A, cAMP-specific
chr17_+_21131940 1.328 NM_002756
MAP2K3
mitogen-activated protein kinase kinase 3
chr11_+_120828275 1.325 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr12_-_6611075 1.325 NM_001142961
LPAR5
lysophosphatidic acid receptor 5
chr16_+_28903647 1.321 NM_001014989
LAT
linker for activation of T cells
chr20_-_24986501 1.314 ACSS1
acyl-CoA synthetase short-chain family member 1
chr15_+_74139325 1.307 NM_152335
C15orf27
chromosome 15 open reading frame 27
chr1_-_7923464 1.306 NM_001561
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr1_+_35104120 1.302


chr2_+_95055155 1.295 NM_002371
NM_022438
NM_022439
NM_022440
MAL



mal, T-cell differentiation protein



chr10_-_98263434 1.295 NM_012465
TLL2
tolloid-like 2
chr5_-_157011949 1.287 NM_007017
NM_178424
SOX30

SRY (sex determining region Y)-box 30

chr19_+_41039649 1.283 NM_032123
NM_199179
NM_199180
KIRREL2


kin of IRRE like 2 (Drosophila)


chr8_-_95343716 1.276 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr19_-_56214765 1.275 NM_145888
KLK10
kallikrein-related peptidase 10
chr2_-_108972100 1.273 NM_022336
EDAR
ectodysplasin A receptor
chr19_-_6542136 1.271 NM_001252
CD70
CD70 molecule
chr19_+_13066956 1.267 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr17_-_1336073 1.261 MYO1C
myosin IC
chr20_+_44180355 1.260 CD40
CD40 molecule, TNF receptor superfamily member 5
chr1_-_92721633 1.253 GFI1
growth factor independent 1 transcription repressor
chr9_-_116608113 1.251 NM_005118
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr10_-_61139328 1.239 NM_194298
LOC100129721
SLC16A9
hypothetical protein LOC100129721
solute carrier family 16, member 9 (monocarboxylic acid transporter 9)
chr1_-_53159759 1.238 ECHDC2
enoyl CoA hydratase domain containing 2
chr19_-_4491024 1.238 NM_052972
LRG1
leucine-rich alpha-2-glycoprotein 1
chr1_-_27834210 1.231 NM_005248
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr1_-_92721943 1.220 NM_001127215
GFI1
growth factor independent 1 transcription repressor
chr3_+_195889845 1.212 FAM43A
family with sequence similarity 43, member A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.44 4.39e-09 GO:0048522 positive regulation of cellular process
1.40 9.94e-09 GO:0048518 positive regulation of biological process
1.79 1.18e-07 GO:0006955 immune response
1.58 4.26e-07 GO:0002376 immune system process
1.82 5.24e-07 GO:0010628 positive regulation of gene expression
1.78 1.24e-06 GO:0002682 regulation of immune system process
1.16 4.85e-06 GO:0065007 biological regulation
1.18 6.50e-06 GO:0050794 regulation of cellular process
1.80 6.60e-06 GO:0045893 positive regulation of transcription, DNA-dependent
1.72 6.86e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
1.37 6.95e-06 GO:0048519 negative regulation of biological process
1.55 1.38e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.74 2.08e-05 GO:0051254 positive regulation of RNA metabolic process
1.89 2.14e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.51 3.78e-05 GO:0009893 positive regulation of metabolic process
1.37 5.19e-05 GO:0048523 negative regulation of cellular process
2.30 6.11e-05 GO:0051249 regulation of lymphocyte activation
1.16 7.76e-05 GO:0050789 regulation of biological process
1.55 8.51e-05 GO:0010941 regulation of cell death
1.55 8.84e-05 GO:0042981 regulation of apoptosis
1.55 8.94e-05 GO:0043067 regulation of programmed cell death
1.64 1.16e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.65 1.34e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.18 2.27e-04 GO:0002694 regulation of leukocyte activation
1.55 3.02e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.49 3.11e-04 GO:0031325 positive regulation of cellular metabolic process
2.14 3.28e-04 GO:0050865 regulation of cell activation
1.25 3.61e-04 GO:0023052 signaling
1.26 4.04e-04 GO:0060255 regulation of macromolecule metabolic process
1.58 4.63e-04 GO:0009891 positive regulation of biosynthetic process
1.58 5.56e-04 GO:0031328 positive regulation of cellular biosynthetic process
1.37 6.43e-04 GO:0048583 regulation of response to stimulus
1.79 1.44e-03 GO:0002684 positive regulation of immune system process
2.32 1.47e-03 GO:0051251 positive regulation of lymphocyte activation
2.01 2.00e-03 GO:0001817 regulation of cytokine production
2.99 3.27e-03 GO:0002699 positive regulation of immune effector process
1.55 3.29e-03 GO:0006952 defense response
2.21 3.68e-03 GO:0002696 positive regulation of leukocyte activation
1.52 3.78e-03 GO:0009611 response to wounding
2.18 5.80e-03 GO:0050867 positive regulation of cell activation
1.67 6.34e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.30 6.35e-03 GO:0051252 regulation of RNA metabolic process
1.16 6.63e-03 GO:0050896 response to stimulus
1.59 6.71e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.53 6.77e-03 GO:0048584 positive regulation of response to stimulus
1.31 6.85e-03 GO:0006355 regulation of transcription, DNA-dependent
1.87 6.91e-03 GO:0031347 regulation of defense response
1.59 7.22e-03 GO:0045595 regulation of cell differentiation
2.26 7.25e-03 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
1.66 7.81e-03 GO:0051253 negative regulation of RNA metabolic process
1.22 9.45e-03 GO:0031323 regulation of cellular metabolic process
1.68 9.62e-03 GO:0009967 positive regulation of signal transduction
1.57 9.85e-03 GO:0009890 negative regulation of biosynthetic process
1.23 9.93e-03 GO:0007165 signal transduction
1.59 1.03e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.26 1.18e-02 GO:0009889 regulation of biosynthetic process
1.61 1.21e-02 GO:0010629 negative regulation of gene expression
1.79 1.37e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.38 1.42e-02 GO:0009966 regulation of signal transduction
1.27 1.48e-02 GO:0010556 regulation of macromolecule biosynthetic process
2.17 1.48e-02 GO:0050863 regulation of T cell activation
2.25 1.51e-02 GO:0002697 regulation of immune effector process
1.48 1.51e-02 GO:0050793 regulation of developmental process
2.19 1.58e-02 GO:0031349 positive regulation of defense response
1.26 1.59e-02 GO:0031326 regulation of cellular biosynthetic process
1.92 1.66e-02 GO:0010740 positive regulation of intracellular protein kinase cascade
1.64 1.72e-02 GO:0010647 positive regulation of cell communication
1.22 1.73e-02 GO:0007275 multicellular organismal development
1.70 1.78e-02 GO:0050776 regulation of immune response
1.59 1.95e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
2.32 2.01e-02 GO:0001819 positive regulation of cytokine production
1.43 2.08e-02 GO:0010646 regulation of cell communication
2.51 2.55e-02 GO:0032944 regulation of mononuclear cell proliferation
1.58 2.61e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.80 2.73e-02 GO:0045597 positive regulation of cell differentiation
1.20 3.31e-02 GO:0019222 regulation of metabolic process
1.24 3.44e-02 GO:0048731 system development
1.38 3.53e-02 GO:0051239 regulation of multicellular organismal process
1.57 3.61e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.68 3.66e-02 GO:0032583 regulation of gene-specific transcription
1.60 3.68e-02 GO:0006928 cellular component movement
1.61 3.96e-02 GO:0023056 positive regulation of signaling
1.51 4.00e-02 GO:2000026 regulation of multicellular organismal development
1.22 4.26e-02 GO:0048856 anatomical structure development
2.54 4.40e-02 GO:0051222 positive regulation of protein transport
2.43 4.49e-02 GO:0070663 regulation of leukocyte proliferation
1.67 4.54e-02 GO:0051094 positive regulation of developmental process
5.15 4.58e-02 GO:0032660 regulation of interleukin-17 production
1.08 4.99e-02 GO:0009987 cellular process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.21 4.74e-04 GO:0071944 cell periphery
1.20 8.00e-04 GO:0005886 plasma membrane
1.29 2.13e-03 GO:0044459 plasma membrane part
1.11 1.67e-02 GO:0016020 membrane
2.12 2.58e-02 GO:0009897 external side of plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.49 5.17e-04 GO:0001071 nucleic acid binding transcription factor activity
1.49 5.17e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.41 1.49e-02 GO:0030528 transcription regulator activity
1.49 2.88e-02 GO:0043565 sequence-specific DNA binding