Motif ID: PATZ1.p2

Z-value: 2.853


Transcription factors associated with PATZ1.p2:

Gene SymbolEntrez IDGene Name
PATZ1 23598 POZ (BTB) and AT hook containing zinc finger 1



Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_150305933 4.002 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr7_-_150306169 3.929 KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chrX_+_138060 3.336 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr2_-_25328452 3.231 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr7_-_100077072 3.017 NM_003227
TFR2
transferrin receptor 2
chr17_+_34114924 2.870 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr16_+_2461500 2.801 NM_006181
NTN3
netrin 3
chr2_-_174537354 2.759 SP3
Sp3 transcription factor
chr19_-_55524445 2.721 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chrX_+_9392980 2.663 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr6_+_7052798 2.659 NM_001168344
RREB1
ras responsive element binding protein 1
chr9_+_94860828 2.652 SUSD3
sushi domain containing 3
chr8_+_144706699 2.589 NM_001166237
GSDMD
gasdermin D
chr19_-_2672337 2.550 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr16_+_1979959 2.535 NM_004209
SYNGR3
synaptogyrin 3
chr19_+_659766 2.520 NM_001040134
NM_002579
PALM

paralemmin

chr9_+_94860769 2.519 NM_145006
SUSD3
sushi domain containing 3
chr2_+_112529270 2.507 NM_032824
TMEM87B
transmembrane protein 87B
chr22_-_21231421 2.454 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr17_-_71352090 2.422 UNC13D
unc-13 homolog D (C. elegans)
chr6_+_34313007 2.421 HMGA1
high mobility group AT-hook 1
chr2_+_42128521 2.388 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr5_-_1348103 2.302 NM_001193376
NM_198253
TERT

telomerase reverse transcriptase

chr17_-_71352017 2.267 UNC13D
unc-13 homolog D (C. elegans)
chr7_-_97868101 2.252 BAIAP2L1
BAI1-associated protein 2-like 1
chr6_+_34312979 2.222 HMGA1
high mobility group AT-hook 1
chr20_+_30813851 2.141 NM_006892
NM_175848
NM_175849
DNMT3B


DNA (cytosine-5-)-methyltransferase 3 beta


chr19_+_45728207 2.125 NM_025213
SPTBN4
spectrin, beta, non-erythrocytic 4
chr17_-_33982580 2.107 SRCIN1
SRC kinase signaling inhibitor 1
chr19_-_1966628 2.060 NM_017797
BTBD2
BTB (POZ) domain containing 2
chr1_-_1283770 2.055 NM_032348
MXRA8
matrix-remodelling associated 8
chr19_+_1397268 2.054 APC2
adenomatosis polyposis coli 2
chr11_-_64268841 2.050 NM_001098670
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr16_+_88542639 2.048 NM_017702
NM_207514
DEF8

differentially expressed in FDCP 8 homolog (mouse)

chr20_+_61841662 2.045 SLC2A4RG
SLC2A4 regulator
chr16_+_29730909 2.002 NM_145239
PRRT2
proline-rich transmembrane protein 2
chr20_+_48240772 1.997 NM_005194
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr16_-_2186465 1.966 NM_020764
CASKIN1
CASK interacting protein 1
chr4_-_6253152 1.965 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr1_+_945331 1.965 NM_198576
AGRN
agrin
chr17_-_37586716 1.965 NM_012285
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr2_+_232281470 1.955 NM_001099285
NM_002823
PTMA

prothymosin, alpha

chr1_-_21868380 1.954 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr19_-_6453224 1.952 NM_006087
TUBB4
tubulin, beta 4
chr19_-_2653662 1.951 GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr3_-_13436725 1.914 NUP210
nucleoporin 210kDa
chr1_-_27802688 1.909 NM_001029882
AHDC1
AT hook, DNA binding motif, containing 1
chr2_+_112529371 1.905 TMEM87B
transmembrane protein 87B
chr16_+_29731058 1.904 PRRT2
proline-rich transmembrane protein 2
chr20_+_44083667 1.888 NM_001134771
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr7_-_102044374 1.887 RASA4
RAS p21 protein activator 4
chr1_-_32574185 1.881 NM_023009
MARCKSL1
MARCKS-like 1
chr20_+_30814048 1.868 DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chr20_-_49592444 1.865 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr22_+_38183480 1.861 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr20_-_44370537 1.831 CDH22
cadherin 22, type 2
chr16_+_2503676 1.827 NM_001198569
NM_001694
ATP6V0C

ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

chr4_-_1156362 1.824 SPON2
spondin 2, extracellular matrix protein
chr4_-_1156378 1.809 SPON2
spondin 2, extracellular matrix protein
chr2_+_232281491 1.803 PTMA
prothymosin, alpha
chr6_+_33495824 1.799 NM_006772
SYNGAP1
synaptic Ras GTPase activating protein 1
chr6_+_7052985 1.776 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr2_-_43306650 1.776 ZFP36L2
zinc finger protein 36, C3H type-like 2
chr20_+_48240867 1.772 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr12_+_54910767 1.769 NM_001135195
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr20_+_61841553 1.764 NM_020062
SLC2A4RG
SLC2A4 regulator
chr1_+_3679168 1.739 NM_001163724
LOC388588
hypothetical protein LOC388588
chr20_-_60963390 1.718 NM_006602
TCFL5
transcription factor-like 5 (basic helix-loop-helix)
chr9_-_122679387 1.715 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr17_-_53420595 1.711 NM_007146
VEZF1
vascular endothelial zinc finger 1
chr12_+_6290359 1.698 NM_001144856
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr22_+_20101661 1.698 NM_015094
HIC2
hypermethylated in cancer 2
chr4_-_1156533 1.683 NM_012445
SPON2
spondin 2, extracellular matrix protein
chr4_-_1156458 1.681 SPON2
spondin 2, extracellular matrix protein
chr3_-_13436802 1.680 NM_024923
NUP210
nucleoporin 210kDa
chr20_+_61839931 1.656 LIME1
Lck interacting transmembrane adaptor 1
chr19_+_40223249 1.655 NM_002151
NM_182983
HPN

hepsin

chr19_+_45728270 1.653 SPTBN4
spectrin, beta, non-erythrocytic 4
chr3_-_39170105 1.622 NM_033027
CSRNP1
cysteine-serine-rich nuclear protein 1
chr17_-_71352182 1.618 NM_199242
UNC13D
unc-13 homolog D (C. elegans)
chr11_+_45900731 1.611 GYLTL1B
glycosyltransferase-like 1B
chr20_+_48240705 1.605 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr19_-_2653738 1.596 NM_052847
GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr19_-_56585603 1.589 NM_001193623
LOC147646
hypothetical protein LOC147646
chr22_-_17546296 1.578 NM_005984
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr19_+_54708389 1.575 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr16_+_2503915 1.574 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr14_-_21064182 1.569 SALL2
sal-like 2 (Drosophila)
chr20_+_60906605 1.565 NM_007346
OGFR
opioid growth factor receptor
chr13_+_112671497 1.559 MCF2L
MCF.2 cell line derived transforming sequence-like
chr7_-_102044419 1.532 NM_001079877
NM_006989
RASA4

RAS p21 protein activator 4

chr11_+_56984702 1.515 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr1_+_3558958 1.514 NM_005427
TP73
tumor protein p73
chr19_-_53950458 1.511 NM_000148
FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr1_+_945399 1.507


chr19_+_40224457 1.505 HPN
hepsin
chr11_+_65049102 1.502 NM_001048218
NM_020680
SCYL1

SCY1-like 1 (S. cerevisiae)

chr17_-_34015631 1.485 NM_025248
SRCIN1
SRC kinase signaling inhibitor 1
chr7_+_5289079 1.483 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr19_-_60350118 1.473 TNNT1
troponin T type 1 (skeletal, slow)
chr17_-_73636362 1.471 TMC6
transmembrane channel-like 6
chr1_+_945472 1.460 AGRN
agrin
chr16_+_29725311 1.444 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr11_-_116213511 1.441 NM_000039
APOA1
apolipoprotein A-I
chr11_-_72170533 1.440 STARD10
StAR-related lipid transfer (START) domain containing 10
chr20_-_3102169 1.440 ProSAPiP1
ProSAPiP1 protein
chr6_-_111911029 1.438 REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr8_-_144887876 1.435 NM_198488
FAM83H
family with sequence similarity 83, member H
chr17_-_73636386 1.429 NM_001127198
TMC6
transmembrane channel-like 6
chr19_-_44503328 1.427


chr20_-_17610704 1.422 RRBP1
ribosome binding protein 1 homolog 180kDa (dog)
chr1_-_36721010 1.415 CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr20_-_62181588 1.410 NM_001039467
RGS19
regulator of G-protein signaling 19
chr17_-_73867748 1.386 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr10_+_124885556 1.384 NM_001105574
HMX3
H6 family homeobox 3
chr20_-_62151216 1.382 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr19_+_10404110 1.376 NM_001111309
PDE4A
phosphodiesterase 4A, cAMP-specific
chr2_-_61551403 1.371 USP34
ubiquitin specific peptidase 34
chr11_+_46358909 1.371 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr12_+_54700955 1.371 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr4_-_1156959 1.364 NM_001128325
SPON2
spondin 2, extracellular matrix protein
chr22_-_17546234 1.356 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr9_+_70509925 1.346 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr19_+_1200882 1.343 MIDN
midnolin
chr20_-_48980858 1.332 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr7_-_100331417 1.330 NM_000665
NM_015831
ACHE

acetylcholinesterase

chr16_+_84202515 1.327 NM_001134473
KIAA0182
KIAA0182
chr7_-_158073121 1.327 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr19_-_60350122 1.323 TNNT1
troponin T type 1 (skeletal, slow)
chr6_-_32265489 1.314 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr19_-_6718417 1.312 NM_005490
SH2D3A
SH2 domain containing 3A
chr22_-_49042065 1.311 NM_002969
MAPK12
mitogen-activated protein kinase 12
chr1_+_224317036 1.311 NM_002107
H3F3A
H3 histone, family 3A
chr2_+_11213020 1.309 PQLC3
PQ loop repeat containing 3
chr17_-_34014390 1.292 SRCIN1
SRC kinase signaling inhibitor 1
chr17_+_35532315 1.292 NM_001012241
MSL1
male-specific lethal 1 homolog (Drosophila)
chr11_+_57121602 1.282 NM_000062
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr11_+_46359781 1.278 NM_002391
MDK
midkine (neurite growth-promoting factor 2)
chr19_+_40451842 1.275 USF2
upstream transcription factor 2, c-fos interacting
chr2_+_181553783 1.272 UBE2E3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr8_-_101803338 1.270 PABPC1
poly(A) binding protein, cytoplasmic 1
chrX_+_152643516 1.267 NM_000033
ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr3_-_39170038 1.255 CSRNP1
cysteine-serine-rich nuclear protein 1
chr19_-_14177980 1.255 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr1_+_154386358 1.253 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr19_-_7607852 1.251


chr16_-_30042083 1.249 NM_001040056
NM_001109891
NM_002746
MAPK3


mitogen-activated protein kinase 3


chr1_-_11636983 1.249 FBXO2
F-box protein 2
chr17_+_72880831 1.249 NM_001113493
SEPT9
septin 9
chr1_+_224317062 1.248 H3F3A
LOC440926
H3 histone, family 3A
H3 histone, family 3A pseudogene
chr2_+_231968578 1.244 NM_145236
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr19_+_12805747 1.243 MAST1
microtubule associated serine/threonine kinase 1
chr6_+_7053183 1.243 RREB1
ras responsive element binding protein 1
chr2_+_170298487 1.243


chr17_-_53420473 1.242 VEZF1
vascular endothelial zinc finger 1
chr17_-_77094375 1.237 NM_001614
ACTG1
actin, gamma 1
chr4_+_2764609 1.236 SH3BP2
SH3-domain binding protein 2
chr17_-_77512346 1.235 NM_178493
NOTUM
notum pectinacetylesterase homolog (Drosophila)
chr14_-_22358752 1.235 NM_001126106
SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr20_-_55533544 1.234 NM_080618
CTCFL
CCCTC-binding factor (zinc finger protein)-like
chr1_+_224317044 1.234 H3F3A
LOC440926
H3 histone, family 3A
H3 histone, family 3A pseudogene
chr13_-_113066366 1.231 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr17_-_24973940 1.229 CORO6
coronin 6
chr22_-_18807805 1.229 PI4KAP2
PI4KAP1
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
chr22_-_17546276 1.224 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr14_-_23117614 1.223 JPH4
junctophilin 4
chr14_+_74964261 1.223 NM_001135047
JDP2
Jun dimerization protein 2
chr2_+_170298700 1.223 KLHL23
kelch-like 23 (Drosophila)
chr20_+_34635362 1.223 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr22_+_49266836 1.221 NM_024866
ADM2
adrenomedullin 2
chr6_-_111911106 1.220 NM_002912
REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr7_+_73136042 1.217 LIMK1
LIM domain kinase 1
chr6_+_44295219 1.213 NM_001078174
NM_004955
SLC29A1

solute carrier family 29 (nucleoside transporters), member 1

chr4_+_1764802 1.200 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chr2_+_11212990 1.190 NM_152391
PQLC3
PQ loop repeat containing 3
chr1_+_225982862 1.190 LOC100130093
hypothetical LOC100130093
chr11_-_65070625 1.188 LTBP3
latent transforming growth factor beta binding protein 3
chr20_-_31737815 1.185 NM_005225
E2F1
E2F transcription factor 1
chr1_+_224317056 1.180 H3F3A
LOC440926
H3 histone, family 3A
H3 histone, family 3A pseudogene
chr1_+_224317030 1.169 H3F3A
H3 histone, family 3A
chr19_+_7608010 1.169 STXBP2
syntaxin binding protein 2
chr2_+_74635019 1.165 NM_001381
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr2_+_11213053 1.161 PQLC3
PQ loop repeat containing 3
chr19_+_40451807 1.160 USF2
upstream transcription factor 2, c-fos interacting
chr17_+_34115383 1.160 NM_005937
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr22_-_37569679 1.159


chr19_-_50688310 1.158 NM_206901
RTN2
reticulon 2
chr20_-_61574259 1.157 NM_004518
NM_172106
NM_172107
NM_172108
NM_172109
KCNQ2




potassium voltage-gated channel, KQT-like subfamily, member 2




chr19_+_8180179 1.152 NM_024552
LASS4
LAG1 homolog, ceramide synthase 4
chr12_-_119826433 1.149 NM_139015
SPPL3
signal peptide peptidase 3
chr20_+_2621193 1.147 NM_001110514
EBF4
early B-cell factor 4
chr19_+_447453 1.146 NM_130760
NM_130762
MADCAM1

mucosal vascular addressin cell adhesion molecule 1

chr7_-_149669622 1.144 NM_002889
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr16_+_29725597 1.143


chr2_+_220087135 1.140 NM_018674
NM_182847
ACCN4

amiloride-sensitive cation channel 4, pituitary

chr17_+_4795128 1.139 NM_001193503
NM_001976
NM_053013
ENO3


enolase 3 (beta, muscle)


chr13_-_113066202 1.138 GRTP1
growth hormone regulated TBC protein 1
chr17_-_77094426 1.136 ACTG1
actin, gamma 1
chr16_+_2503978 1.133 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr19_+_14405216 1.133 PKN1
protein kinase N1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 9.06e-26 GO:0009987 cellular process
1.13 3.40e-18 GO:0044237 cellular metabolic process
1.15 2.02e-15 GO:0044260 cellular macromolecule metabolic process
1.11 1.67e-12 GO:0044238 primary metabolic process
1.16 2.07e-12 GO:0016043 cellular component organization
1.09 2.33e-12 GO:0065007 biological regulation
1.10 2.51e-12 GO:0008152 metabolic process
1.10 5.01e-12 GO:0050794 regulation of cellular process
1.52 5.59e-12 GO:0016568 chromatin modification
1.18 2.82e-11 GO:0071842 cellular component organization at cellular level
1.22 3.61e-11 GO:0006464 protein modification process
1.23 7.38e-11 GO:0006996 organelle organization
1.15 8.22e-11 GO:0031323 regulation of cellular metabolic process
1.15 8.73e-11 GO:0071840 cellular component organization or biogenesis
1.15 1.57e-10 GO:0060255 regulation of macromolecule metabolic process
1.09 2.14e-10 GO:0050789 regulation of biological process
1.15 4.76e-10 GO:0080090 regulation of primary metabolic process
1.17 1.34e-09 GO:0071841 cellular component organization or biogenesis at cellular level
1.11 2.78e-09 GO:0043170 macromolecule metabolic process
1.13 3.74e-09 GO:0019222 regulation of metabolic process
1.19 8.00e-09 GO:0043412 macromolecule modification
1.27 1.05e-08 GO:0007049 cell cycle
1.17 1.90e-08 GO:0044267 cellular protein metabolic process
1.16 2.64e-08 GO:0010468 regulation of gene expression
1.17 4.16e-08 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.16 1.72e-07 GO:0010556 regulation of macromolecule biosynthetic process
1.37 6.86e-07 GO:0006325 chromatin organization
1.16 1.69e-06 GO:0048523 negative regulation of cellular process
1.14 3.89e-06 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24 5.30e-06 GO:0032268 regulation of cellular protein metabolic process
1.30 5.42e-06 GO:0051726 regulation of cell cycle
1.14 6.45e-06 GO:0048518 positive regulation of biological process
1.14 7.34e-06 GO:0031326 regulation of cellular biosynthetic process
1.30 7.59e-06 GO:0051276 chromosome organization
1.14 9.05e-06 GO:0009889 regulation of biosynthetic process
1.26 9.21e-06 GO:0022402 cell cycle process
1.23 9.77e-06 GO:0051246 regulation of protein metabolic process
1.15 1.05e-05 GO:0051252 regulation of RNA metabolic process
1.54 1.42e-05 GO:0016569 covalent chromatin modification
1.14 1.64e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.54 2.12e-05 GO:0016570 histone modification
1.19 3.38e-05 GO:0007399 nervous system development
1.13 4.37e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.14 4.85e-05 GO:0048519 negative regulation of biological process
1.24 5.63e-05 GO:0010605 negative regulation of macromolecule metabolic process
1.14 5.96e-05 GO:0048522 positive regulation of cellular process
1.12 7.13e-05 GO:0006807 nitrogen compound metabolic process
1.12 7.63e-05 GO:0034641 cellular nitrogen compound metabolic process
1.22 7.97e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.18 8.65e-05 GO:0009056 catabolic process
1.14 1.56e-04 GO:0006355 regulation of transcription, DNA-dependent
1.20 1.59e-04 GO:0044248 cellular catabolic process
1.23 1.60e-04 GO:0048468 cell development
1.22 3.38e-04 GO:0031324 negative regulation of cellular metabolic process
1.21 4.92e-04 GO:0009892 negative regulation of metabolic process
1.41 5.10e-04 GO:0016567 protein ubiquitination
1.36 5.98e-04 GO:0070647 protein modification by small protein conjugation or removal
1.23 7.45e-04 GO:0051128 regulation of cellular component organization
1.11 1.09e-03 GO:0019538 protein metabolic process
1.38 1.28e-03 GO:0010608 posttranscriptional regulation of gene expression
1.14 1.51e-03 GO:0030154 cell differentiation
1.34 1.66e-03 GO:0018193 peptidyl-amino acid modification
1.15 1.74e-03 GO:0009059 macromolecule biosynthetic process
1.15 1.78e-03 GO:0034645 cellular macromolecule biosynthetic process
1.17 2.62e-03 GO:0033036 macromolecule localization
1.24 3.06e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.23 3.14e-03 GO:0016192 vesicle-mediated transport
1.11 3.21e-03 GO:0006810 transport
1.37 3.33e-03 GO:0032446 protein modification by small protein conjugation
1.41 3.39e-03 GO:0045786 negative regulation of cell cycle
1.12 3.47e-03 GO:0044249 cellular biosynthetic process
1.24 3.63e-03 GO:0030030 cell projection organization
1.13 3.76e-03 GO:0090304 nucleic acid metabolic process
1.20 4.68e-03 GO:0022008 neurogenesis
1.24 4.76e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.27 4.82e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.27 4.85e-03 GO:0007010 cytoskeleton organization
1.12 5.49e-03 GO:0009058 biosynthetic process
1.38 5.55e-03 GO:0051248 negative regulation of protein metabolic process
1.10 5.61e-03 GO:0051234 establishment of localization
1.10 5.64e-03 GO:0051179 localization
1.13 6.25e-03 GO:0048869 cellular developmental process
1.21 6.38e-03 GO:0031399 regulation of protein modification process
1.22 6.61e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.18 7.06e-03 GO:0022607 cellular component assembly
1.17 7.26e-03 GO:0051641 cellular localization
1.31 7.99e-03 GO:0044419 interspecies interaction between organisms
1.25 8.17e-03 GO:0000278 mitotic cell cycle
1.27 8.27e-03 GO:0031175 neuron projection development
1.14 8.28e-03 GO:0023051 regulation of signaling
1.20 8.86e-03 GO:0048699 generation of neurons
1.19 9.35e-03 GO:0006793 phosphorus metabolic process
1.19 9.35e-03 GO:0006796 phosphate metabolic process
1.27 9.62e-03 GO:0000904 cell morphogenesis involved in differentiation
1.20 1.06e-02 GO:0008219 cell death
1.20 1.41e-02 GO:0016265 death
1.22 1.52e-02 GO:0022403 cell cycle phase
1.26 1.94e-02 GO:0070271 protein complex biogenesis
1.17 2.01e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.61 2.03e-02 GO:0018205 peptidyl-lysine modification
1.22 2.15e-02 GO:0009790 embryo development
1.36 2.16e-02 GO:0032269 negative regulation of cellular protein metabolic process
1.09 2.27e-02 GO:0032502 developmental process
1.64 2.39e-02 GO:0000209 protein polyubiquitination
1.26 2.54e-02 GO:0006461 protein complex assembly
1.68 2.63e-02 GO:0006475 internal protein amino acid acetylation
1.51 2.63e-02 GO:0007265 Ras protein signal transduction
1.21 2.65e-02 GO:0009890 negative regulation of biosynthetic process
1.23 2.67e-02 GO:0009057 macromolecule catabolic process
1.24 2.83e-02 GO:0048666 neuron development
1.43 3.28e-02 GO:0006417 regulation of translation
1.37 3.45e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.21 3.49e-02 GO:0010628 positive regulation of gene expression
1.19 3.79e-02 GO:0006351 transcription, DNA-dependent
1.63 3.96e-02 GO:0007173 epidermal growth factor receptor signaling pathway
1.21 4.00e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.67 4.45e-02 GO:0018394 peptidyl-lysine acetylation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.11 1.03e-52 GO:0044424 intracellular part
1.11 1.77e-52 GO:0005622 intracellular
1.13 6.20e-38 GO:0043227 membrane-bounded organelle
1.13 1.06e-37 GO:0043231 intracellular membrane-bounded organelle
1.13 3.98e-36 GO:0005737 cytoplasm
1.11 7.98e-36 GO:0043226 organelle
1.11 9.71e-36 GO:0043229 intracellular organelle
1.16 2.45e-26 GO:0005634 nucleus
1.13 1.42e-20 GO:0044444 cytoplasmic part
1.13 1.78e-18 GO:0044446 intracellular organelle part
1.13 3.44e-18 GO:0044422 organelle part
1.24 1.12e-17 GO:0044428 nuclear part
1.24 1.02e-14 GO:0031981 nuclear lumen
1.22 2.36e-14 GO:0005829 cytosol
1.20 1.77e-12 GO:0070013 intracellular organelle lumen
1.26 2.30e-12 GO:0005654 nucleoplasm
1.19 3.41e-12 GO:0043233 organelle lumen
1.19 8.77e-12 GO:0031974 membrane-enclosed lumen
1.14 7.05e-09 GO:0043234 protein complex
1.19 2.20e-07 GO:0012505 endomembrane system
1.28 7.78e-07 GO:0044451 nucleoplasm part
1.03 1.00e-06 GO:0044464 cell part
1.03 1.12e-06 GO:0005623 cell
1.11 1.40e-06 GO:0032991 macromolecular complex
1.23 1.86e-06 GO:0005794 Golgi apparatus
1.27 2.91e-06 GO:0015630 microtubule cytoskeleton
1.28 1.54e-05 GO:0044431 Golgi apparatus part
1.29 1.89e-05 GO:0005694 chromosome
1.50 4.31e-05 GO:0044454 nuclear chromosome part
1.45 5.45e-05 GO:0000228 nuclear chromosome
1.48 7.11e-05 GO:0031252 cell leading edge
1.30 8.76e-05 GO:0044427 chromosomal part
1.49 1.45e-04 GO:0070161 anchoring junction
1.62 2.34e-04 GO:0005925 focal adhesion
1.13 2.71e-04 GO:0031090 organelle membrane
1.57 5.31e-04 GO:0030055 cell-substrate junction
1.66 5.54e-04 GO:0000790 nuclear chromatin
1.44 7.46e-04 GO:0005819 spindle
1.22 9.07e-04 GO:0031988 membrane-bounded vesicle
1.11 1.23e-03 GO:0043228 non-membrane-bounded organelle
1.11 1.23e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.56 1.27e-03 GO:0005924 cell-substrate adherens junction
1.21 1.37e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.26 2.09e-03 GO:0000139 Golgi membrane
1.20 3.18e-03 GO:0031982 vesicle
1.20 3.39e-03 GO:0031410 cytoplasmic vesicle
1.32 5.15e-03 GO:0015629 actin cytoskeleton
1.43 7.03e-03 GO:0005912 adherens junction
1.34 7.50e-03 GO:0000785 chromatin
1.21 1.25e-02 GO:0030054 cell junction
1.28 1.31e-02 GO:0005815 microtubule organizing center
1.27 1.32e-02 GO:0048471 perinuclear region of cytoplasm
1.77 1.89e-02 GO:0000792 heterochromatin
1.63 2.01e-02 GO:0000123 histone acetyltransferase complex
1.34 2.10e-02 GO:0016604 nuclear body
1.53 2.47e-02 GO:0001726 ruffle
1.78 2.81e-02 GO:0008287 protein serine/threonine phosphatase complex
1.12 3.70e-02 GO:0005856 cytoskeleton
1.32 4.86e-02 GO:0005813 centrosome

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.16 2.28e-41 GO:0005515 protein binding
1.08 6.72e-32 GO:0005488 binding
1.41 1.99e-09 GO:0019904 protein domain specific binding
1.31 6.35e-09 GO:0019899 enzyme binding
1.34 8.33e-08 GO:0008092 cytoskeletal protein binding
1.16 2.22e-07 GO:0000166 nucleotide binding
1.09 1.78e-06 GO:0003824 catalytic activity
1.48 2.30e-06 GO:0019787 small conjugating protein ligase activity
1.12 5.38e-06 GO:0003676 nucleic acid binding
1.24 6.78e-06 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.48 7.13e-06 GO:0004842 ubiquitin-protein ligase activity
1.37 6.58e-05 GO:0003779 actin binding
1.48 6.65e-05 GO:0003682 chromatin binding
1.24 8.03e-05 GO:0016301 kinase activity
1.20 1.36e-04 GO:0030528 transcription regulator activity
1.25 1.37e-04 GO:0043565 sequence-specific DNA binding
1.13 1.40e-04 GO:0003677 DNA binding
1.24 1.97e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.37 2.15e-04 GO:0008134 transcription factor binding
1.15 3.05e-04 GO:0016740 transferase activity
1.37 7.05e-04 GO:0016881 acid-amino acid ligase activity
1.35 7.28e-04 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.19 7.65e-04 GO:0001071 nucleic acid binding transcription factor activity
1.19 7.65e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.28 1.54e-03 GO:0004674 protein serine/threonine kinase activity
1.39 4.04e-03 GO:0000975 regulatory region DNA binding
1.39 4.04e-03 GO:0001067 regulatory region nucleic acid binding
1.39 4.04e-03 GO:0044212 transcription regulatory region DNA binding
1.29 5.45e-03 GO:0003712 transcription cofactor activity
1.13 5.82e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.28 6.87e-03 GO:0000988 protein binding transcription factor activity
1.28 6.87e-03 GO:0000989 transcription factor binding transcription factor activity
1.23 6.88e-03 GO:0004672 protein kinase activity
1.36 8.21e-03 GO:0019900 kinase binding
1.39 8.32e-03 GO:0010843 promoter binding
1.12 1.69e-02 GO:0032553 ribonucleotide binding
1.12 1.69e-02 GO:0032555 purine ribonucleotide binding
1.13 1.81e-02 GO:0005524 ATP binding
1.08 2.54e-02 GO:0043169 cation binding
1.13 2.68e-02 GO:0032559 adenyl ribonucleotide binding
1.12 2.85e-02 GO:0017076 purine nucleotide binding
1.08 2.91e-02 GO:0043167 ion binding
1.24 3.12e-02 GO:0016874 ligase activity
1.20 3.17e-02 GO:0046983 protein dimerization activity
1.13 3.83e-02 GO:0030554 adenyl nucleotide binding
1.29 4.03e-02 GO:0016564 transcription repressor activity
1.48 4.06e-02 GO:0017124 SH3 domain binding
1.34 4.31e-02 GO:0003713 transcription coactivator activity