Motif ID: PAX5.p2

Z-value: 1.420


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5



Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_233879617 4.317 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr16_-_66827449 3.046 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr13_-_43351825 2.854 NM_144974
CCDC122
coiled-coil domain containing 122
chr19_+_8180179 2.424 NM_024552
LASS4
LAG1 homolog, ceramide synthase 4
chr13_+_43351968 2.406 NM_153218
C13orf31
chromosome 13 open reading frame 31
chr2_-_36384 2.379 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr19_+_61742111 2.334 NM_020828
ZFP28
zinc finger protein 28 homolog (mouse)
chr7_-_107883929 2.036 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr10_+_135042684 2.028 NM_152911
NM_207127
NM_207128
PAOX


polyamine oxidase (exo-N4-amino)


chr2_-_127694123 1.984 CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr15_-_50375143 1.895 NM_018728
MYO5C
myosin VC
chr14_-_94855848 1.876 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr12_-_93568336 1.793 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr5_+_17270474 1.746 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr16_-_265868 1.730 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr15_+_99237527 1.725 NM_000693
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr10_-_30064600 1.665 NM_003174
SVIL
supervillin
chr17_+_27617307 1.594 NM_138328
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr2_-_88533167 1.591 NM_001135649
FOXI3
forkhead box I3
chr9_-_91302707 1.552 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr11_-_60819273 1.532 NM_152718
VWCE
von Willebrand factor C and EGF domains
chr10_-_105604942 1.522 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr2_-_98714020 1.509 NM_012214
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr5_+_175725050 1.502 NM_173664
ARL10
ADP-ribosylation factor-like 10
chr20_-_38751289 1.499 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr10_-_71575953 1.489 TYSND1
trypsin domain containing 1
chr13_+_43845977 1.464 NM_001010897
SERP2
stress-associated endoplasmic reticulum protein family member 2
chr10_+_131155443 1.458 NM_002412
MGMT
O-6-methylguanine-DNA methyltransferase
chr1_+_61980679 1.435 NM_176877
INADL
InaD-like (Drosophila)
chr10_+_131155490 1.433 MGMT
O-6-methylguanine-DNA methyltransferase
chr5_+_17270781 1.432 BASP1
brain abundant, membrane attached signal protein 1
chr17_-_59131194 1.430 LIMD2
LIM domain containing 2
chr3_+_32255158 1.425 NM_178868
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr1_-_2333800 1.390 PEX10
peroxisomal biogenesis factor 10
chr4_-_7991992 1.379 NM_001134647
NM_198595
AFAP1

actin filament associated protein 1

chr19_-_47619992 1.343 LIPE
lipase, hormone-sensitive
chr18_-_68685789 1.336 NM_138966
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr14_-_99842519 1.324 NM_001039355
SLC25A29
solute carrier family 25, member 29
chr11_+_8059267 1.314 NM_177972
TUB
tubby homolog (mouse)
chr6_-_89884324 1.305 NM_080743
SRSF12
serine/arginine-rich splicing factor 12
chr22_-_49317408 1.293 ODF3B
outer dense fiber of sperm tails 3B
chr4_-_809879 1.283 NM_006651
CPLX1
complexin 1
chr1_+_38032045 1.278 NM_001031740
NM_001113482
MANEAL

mannosidase, endo-alpha-like

chr20_+_1154763 1.275 NM_001136566
RAD21L1
RAD21-like 1 (S. pombe)
chr14_-_91372365 1.264 NM_001128595
NM_152332
TC2N

tandem C2 domains, nuclear

chr19_-_19599973 1.263 NM_004720
LPAR2
lysophosphatidic acid receptor 2
chr11_-_60819110 1.261 VWCE
von Willebrand factor C and EGF domains
chr19_-_242335 1.257 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr10_+_42892506 1.211 NM_020630
NM_020975
RET

ret proto-oncogene

chr5_+_43228083 1.209 NM_153361
MGC42105
serine/threonine-protein kinase NIM1
chr1_-_2333863 1.200 NM_002617
NM_153818
PEX10

peroxisomal biogenesis factor 10

chr9_+_138497767 1.195 NM_152571
C9orf163
chromosome 9 open reading frame 163
chr5_+_68824143 1.185 OCLN
occludin
chr13_+_34414390 1.179 NM_015678
NBEA
neurobeachin
chr17_+_40565492 1.171 NM_001135704
ACBD4
acyl-CoA binding domain containing 4
chr7_-_117300763 1.165 NM_033427
CTTNBP2
cortactin binding protein 2
chr3_+_32255215 1.161 CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr14_+_102128741 1.154 RCOR1
REST corepressor 1
chr5_+_139155569 1.145 NM_032289
PSD2
pleckstrin and Sec7 domain containing 2
chr5_+_96023926 1.144 CAST
calpastatin
chr14_+_93710401 1.143 NM_020958
NM_058237
PPP4R4

protein phosphatase 4, regulatory subunit 4

chr22_-_36153449 1.143 NM_052906
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr21_+_32706615 1.140 NM_058187
C21orf63
chromosome 21 open reading frame 63
chr8_-_26427304 1.133 NM_007257
PNMA2
paraneoplastic antigen MA2
chr8_+_26427378 1.124 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr13_+_43351419 1.118 NM_001128303
C13orf31
chromosome 13 open reading frame 31
chr3_-_49289285 1.116 NM_198562
C3orf62
chromosome 3 open reading frame 62
chr2_-_98713862 1.107 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr3_+_133923758 1.102 NCRNA00119
non-protein coding RNA 119
chr3_-_53054999 1.086 SFMBT1
Scm-like with four mbt domains 1
chr16_+_65790514 1.077 NM_024712
ELMO3
engulfment and cell motility 3
chr2_+_231968578 1.074 NM_145236
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chrX_+_43399101 1.073 MAOA
monoamine oxidase A
chr19_+_39664706 1.070 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr8_+_25097983 1.069 DOCK5
dedicator of cytokinesis 5
chr13_-_27572646 1.066 NM_004119
FLT3
fms-related tyrosine kinase 3
chr17_-_1029758 1.062 NM_021962
ABR
active BCR-related gene
chr3_-_53055078 1.032 NM_001005158
NM_016329
SFMBT1

Scm-like with four mbt domains 1

chr6_-_80713589 1.030 NM_022726
ELOVL4
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
chr1_-_233880676 1.030 NM_001098721
NM_004485
GNG4

guanine nucleotide binding protein (G protein), gamma 4

chr17_-_78249750 1.028 NM_006822
RAB40B
RAB40B, member RAS oncogene family
chr4_+_7245218 1.024 NM_020777
SORCS2
sortilin-related VPS10 domain containing receptor 2
chr2_-_106869949 1.012 NM_001142352
NM_032528
ST6GAL2

ST6 beta-galactosamide alpha-2,6-sialyltranferase 2

chr2_+_176761552 1.010 NM_024501
HOXD1
homeobox D1
chr5_+_167889123 1.008


chr4_+_3264509 1.000 RGS12
regulator of G-protein signaling 12
chr16_-_17472238 0.998 NM_022166
XYLT1
xylosyltransferase I
chr1_+_221633337 0.997 NM_152610
C1orf65
chromosome 1 open reading frame 65
chr22_+_49459935 0.996 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr16_-_4528380 0.996 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr2_-_128792515 0.992 NM_004807
HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr2_+_233448739 0.984 C2orf82
chromosome 2 open reading frame 82
chr21_-_43671355 0.983 NM_173354
SIK1
salt-inducible kinase 1
chr1_-_199704773 0.978 NM_012396
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr8_+_120289735 0.977 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr6_+_36206239 0.973 NM_002754
MAPK13
mitogen-activated protein kinase 13
chr2_+_238265519 0.971 NM_001137551
NM_001137552
NM_001137553
NM_004735
LRRFIP1



leucine rich repeat (in FLII) interacting protein 1



chr11_-_45643711 0.971 NM_003654
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr16_+_11669736 0.971 NM_003498
SNN
stannin
chr19_+_46574277 0.967 NM_001098821
NM_001098822
NM_001098823
NM_001098824
TMEM91



transmembrane protein 91



chr1_+_15957832 0.958 NM_017556
FBLIM1
filamin binding LIM protein 1
chr15_+_49421004 0.955 NM_181789
GLDN
gliomedin
chr3_+_53170254 0.955 NM_006254
NM_212539
PRKCD

protein kinase C, delta

chr15_+_99237555 0.928 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr14_+_89597860 0.925 NM_022054
KCNK13
potassium channel, subfamily K, member 13
chr3_+_120904555 0.923 NM_033364
C3orf15
chromosome 3 open reading frame 15
chr1_+_107485071 0.920 NTNG1
netrin G1
chr16_+_87047418 0.916 NM_153813
ZFPM1
zinc finger protein, multitype 1
chr1_-_48235148 0.915 NM_001194986
LOC388630
UPF0632 protein A
chr3_-_126414252 0.909 NM_024628
SLC12A8
solute carrier family 12 (potassium/chloride transporters), member 8
chr8_-_101227203 0.907 NM_001029860
FBXO43
F-box protein 43
chr11_+_118544625 0.907 NM_024618
NM_170722
NLRX1

NLR family member X1

chr17_-_43470134 0.904 NM_016429
COPZ2
coatomer protein complex, subunit zeta 2
chr9_-_6635564 0.903 NM_000170
GLDC
glycine dehydrogenase (decarboxylating)
chr8_+_25098296 0.898 DOCK5
dedicator of cytokinesis 5
chr18_-_7107757 0.890 NM_005559
LAMA1
laminin, alpha 1
chr20_-_49818306 0.885 NM_006045
ATP9A
ATPase, class II, type 9A
chr17_-_53387493 0.877 CUEDC1
CUE domain containing 1
chr14_+_103251798 0.876 NM_001198953
NM_024071
ZFYVE21

zinc finger, FYVE domain containing 21

chr1_+_208178198 0.874 SYT14
synaptotagmin XIV
chr19_+_61798434 0.874 NM_021216
ZNF71
zinc finger protein 71
chr10_+_129595349 0.871 PTPRE
protein tyrosine phosphatase, receptor type, E
chr2_+_27163114 0.867 NM_000221
NM_006488
KHK

ketohexokinase (fructokinase)

chr1_+_199127242 0.866 NM_018265
C1orf106
chromosome 1 open reading frame 106
chr18_+_17076166 0.866 NM_001142966
GREB1L
growth regulation by estrogen in breast cancer-like
chr11_-_64247230 0.865 NM_015080
NM_138732
NRXN2

neurexin 2

chr14_+_104935897 0.862 NM_001195082
LOC647310
testis expressed gene 22
chr5_+_135392482 0.860 NM_000358
TGFBI
transforming growth factor, beta-induced, 68kDa
chr22_+_48966394 0.859 TRABD
TraB domain containing
chr15_+_57517564 0.858 NM_152450
FAM81A
family with sequence similarity 81, member A
chr7_-_150847884 0.853 NM_005614
RHEB
Ras homolog enriched in brain
chr7_-_117300702 0.853 CTTNBP2
cortactin binding protein 2
chr6_+_17389752 0.852 NM_001143942
RBM24
RNA binding motif protein 24
chr2_+_235525355 0.848 NM_014521
SH3BP4
SH3-domain binding protein 4
chr11_+_7997366 0.847 TUB
tubby homolog (mouse)
chr17_+_77780177 0.841 NM_004207
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr1_-_223907283 0.840 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr3_+_9826930 0.840 TTLL3
tubulin tyrosine ligase-like family, member 3
chr14_+_102128844 0.839 NM_015156
RCOR1
REST corepressor 1
chr12_+_13044604 0.838 HTR7P1
5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
chr20_-_61933012 0.837 ZBTB46
zinc finger and BTB domain containing 46
chr8_+_25098171 0.836 NM_024940
DOCK5
dedicator of cytokinesis 5
chr17_-_25112393 0.835 SSH2
slingshot homolog 2 (Drosophila)
chr14_+_20608179 0.832 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr10_-_71576335 0.830


chr1_-_6468108 0.829 PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr1_-_19998955 0.829 NM_181719
TMCO4
transmembrane and coiled-coil domains 4
chr13_+_35904408 0.827 NM_001111045
NM_003914
CCNA1

cyclin A1

chr4_-_83702123 0.827 NM_001080506
TMEM150C
transmembrane protein 150C
chr5_-_114533448 0.826 TRIM36
tripartite motif containing 36
chr22_-_26527469 0.823 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr17_-_1412774 0.823 NM_006224
PITPNA
phosphatidylinositol transfer protein, alpha
chr1_+_1971762 0.822 NM_002744
PRKCZ
protein kinase C, zeta
chr3_-_127558747 0.816 NM_014079
KLF15
Kruppel-like factor 15
chr20_+_8060762 0.816 NM_015192
NM_182734
PLCB1

phospholipase C, beta 1 (phosphoinositide-specific)

chr17_+_77779570 0.816 NM_001042422
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr8_+_136538739 0.815 NM_006558
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr1_-_6243621 0.814 NM_207370
GPR153
G protein-coupled receptor 153
chr5_+_68823874 0.807 NM_002538
OCLN
occludin
chr5_-_58370693 0.798 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr11_+_22171150 0.795 NM_001142649
NM_213599
ANO5

anoctamin 5

chr20_-_49818268 0.795 ATP9A
ATPase, class II, type 9A
chr4_+_995609 0.787 NM_001004356
NM_001004358
FGFRL1

fibroblast growth factor receptor-like 1

chr10_-_131652364 0.780 EBF3
early B-cell factor 3
chr4_-_170428681 0.779 SH3RF1
SH3 domain containing ring finger 1
chr3_-_51976428 0.779 NM_020418
NM_001174100
NM_033008
PCBP4


poly(rC) binding protein 4


chr4_+_72271218 0.776 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr2_+_9532087 0.776 NM_001039613
IAH1
isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
chr10_-_135036805 0.776 NM_004092
ECHS1
enoyl CoA hydratase, short chain, 1, mitochondrial
chr17_+_78630793 0.775 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr17_-_24068759 0.769 NM_001144942
NM_031934
RAB34

RAB34, member RAS oncogene family

chr3_-_185461768 0.767 NM_033259
CAMK2N2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr2_+_242289983 0.767 NM_032329
ING5
inhibitor of growth family, member 5
chr2_-_20288647 0.766 NM_001006946
SDC1
syndecan 1
chr9_-_139068269 0.762 NM_001246
NM_203468
ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2

chr7_+_1536847 0.761 NM_002360
MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr10_+_134972902 0.759


chr6_-_10527772 0.756 NM_001042425
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr2_-_128149112 0.755 NM_001136037
NM_001161403
LIMS2

LIM and senescent cell antigen-like domains 2

chr15_-_58671929 0.747 NM_134262
RORA
RAR-related orphan receptor A
chr15_+_92575767 0.747 MCTP2
multiple C2 domains, transmembrane 2
chr22_-_39964001 0.745 CHADL
chondroadherin-like
chr2_-_42574587 0.745 NM_133329
NM_172344
KCNG3

potassium voltage-gated channel, subfamily G, member 3

chr4_-_170428564 0.744 SH3RF1
SH3 domain containing ring finger 1
chrX_-_1531733 0.744 NM_001173474
NM_004192
ASMTL

acetylserotonin O-methyltransferase-like

chr8_-_37876129 0.741 NM_001002814
NM_025151
RAB11FIP1

RAB11 family interacting protein 1 (class I)

chr11_+_120828058 0.738 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr17_+_43165608 0.738 NM_013351
TBX21
T-box 21
chr7_+_55054152 0.737 NM_005228
NM_201282
NM_201283
NM_201284
EGFR



epidermal growth factor receptor



chr3_+_54131731 0.735 NM_018398
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr16_-_66258072 0.731 NM_032140
C16orf48
chromosome 16 open reading frame 48
chr16_-_11588525 0.731 LITAF
lipopolysaccharide-induced TNF factor
chr12_-_105165805 0.730 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr1_-_85131439 0.728 NM_012152
LPAR3
lysophosphatidic acid receptor 3
chr11_-_19219720 0.725 E2F8
E2F transcription factor 8
chr3_-_198180005 0.725 NM_025163
PIGZ
phosphatidylinositol glycan anchor biosynthesis, class Z
chr16_-_65742323 0.723 NM_033309
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr2_-_135193011 0.722 NM_030923
TMEM163
transmembrane protein 163
chr5_-_168660293 0.713 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr21_+_17807167 0.712 NM_001338
CXADR
coxsackie virus and adenovirus receptor

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.13 7.54e-16 GO:0050794 regulation of cellular process
1.12 3.52e-15 GO:0065007 biological regulation
1.12 8.45e-14 GO:0050789 regulation of biological process
1.27 2.34e-10 GO:0023051 regulation of signaling
1.23 5.78e-10 GO:0048523 negative regulation of cellular process
1.29 6.03e-10 GO:0009966 regulation of signal transduction
1.06 4.28e-09 GO:0009987 cellular process
1.16 8.48e-09 GO:0023052 signaling
1.26 1.96e-08 GO:0007399 nervous system development
1.20 5.42e-08 GO:0048519 negative regulation of biological process
1.57 7.15e-08 GO:0060284 regulation of cell development
1.16 8.41e-08 GO:0007165 signal transduction
1.32 1.00e-06 GO:0048699 generation of neurons
1.31 1.50e-06 GO:0022008 neurogenesis
1.23 5.34e-06 GO:0009653 anatomical structure morphogenesis
1.20 6.43e-06 GO:0048583 regulation of response to stimulus
1.19 6.74e-06 GO:0048869 cellular developmental process
1.37 7.58e-06 GO:0000902 cell morphogenesis
1.17 9.65e-06 GO:0048522 positive regulation of cellular process
1.16 9.67e-06 GO:0048518 positive regulation of biological process
1.19 1.90e-05 GO:0030154 cell differentiation
1.12 2.11e-05 GO:0051716 cellular response to stimulus
1.35 3.00e-05 GO:0032989 cellular component morphogenesis
1.13 3.61e-05 GO:0031323 regulation of cellular metabolic process
1.39 4.05e-05 GO:0000904 cell morphogenesis involved in differentiation
1.31 5.57e-05 GO:2000026 regulation of multicellular organismal development
1.26 6.84e-05 GO:0010646 regulation of cell communication
1.13 6.85e-05 GO:0080090 regulation of primary metabolic process
1.12 7.61e-05 GO:0032502 developmental process
1.32 1.22e-04 GO:0045595 regulation of cell differentiation
1.13 1.33e-04 GO:0007275 multicellular organismal development
1.27 1.42e-04 GO:0050793 regulation of developmental process
1.41 1.52e-04 GO:0009968 negative regulation of signal transduction
1.49 1.55e-04 GO:0040012 regulation of locomotion
1.12 1.57e-04 GO:0019222 regulation of metabolic process
1.51 1.97e-04 GO:0030334 regulation of cell migration
1.50 2.34e-04 GO:2000145 regulation of cell motility
1.57 2.53e-04 GO:0045664 regulation of neuron differentiation
1.35 2.73e-04 GO:0051253 negative regulation of RNA metabolic process
1.35 2.94e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.13 3.24e-04 GO:0060255 regulation of macromolecule metabolic process
1.42 3.33e-04 GO:0051056 regulation of small GTPase mediated signal transduction
1.51 4.25e-04 GO:0050767 regulation of neurogenesis
1.21 5.34e-04 GO:0035556 intracellular signal transduction
1.14 6.67e-04 GO:0048731 system development
1.31 6.98e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.46 7.94e-04 GO:0051270 regulation of cellular component movement
1.13 8.22e-04 GO:0048856 anatomical structure development
1.31 9.13e-04 GO:0030030 cell projection organization
1.83 1.03e-03 GO:0060828 regulation of canonical Wnt receptor signaling pathway
1.14 1.33e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.46 1.50e-03 GO:0035295 tube development
1.25 1.51e-03 GO:0048468 cell development
1.31 1.51e-03 GO:0010629 negative regulation of gene expression
1.14 1.92e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.33 2.03e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.28 2.08e-03 GO:0030182 neuron differentiation
1.34 2.21e-03 GO:0048858 cell projection morphogenesis
1.14 2.35e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.50 2.42e-03 GO:0002009 morphogenesis of an epithelium
1.14 2.48e-03 GO:0010468 regulation of gene expression
1.14 2.70e-03 GO:0031326 regulation of cellular biosynthetic process
1.45 2.86e-03 GO:0051960 regulation of nervous system development
1.66 3.02e-03 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.65 4.49e-03 GO:0022604 regulation of cell morphogenesis
1.32 4.65e-03 GO:0032990 cell part morphogenesis
1.29 5.00e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14 5.51e-03 GO:0051252 regulation of RNA metabolic process
1.63 5.86e-03 GO:0030111 regulation of Wnt receptor signaling pathway
1.15 5.86e-03 GO:0006355 regulation of transcription, DNA-dependent
1.29 6.60e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.23 6.79e-03 GO:0032879 regulation of localization
1.53 7.29e-03 GO:0035239 tube morphogenesis
1.34 7.29e-03 GO:0048812 neuron projection morphogenesis
1.29 8.19e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.13 9.29e-03 GO:0009889 regulation of biosynthetic process
1.32 9.35e-03 GO:0048585 negative regulation of response to stimulus
1.35 1.10e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.27 1.12e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.40 1.20e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.32 1.22e-02 GO:0031175 neuron projection development
1.35 1.28e-02 GO:0007264 small GTPase mediated signal transduction
1.27 1.29e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.13 1.32e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.40 1.38e-02 GO:0048729 tissue morphogenesis
1.33 1.62e-02 GO:0010648 negative regulation of cell communication
1.19 1.63e-02 GO:0051239 regulation of multicellular organismal process
1.22 1.68e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.26 1.80e-02 GO:0009890 negative regulation of biosynthetic process
1.29 1.80e-02 GO:0048666 neuron development
1.11 1.89e-02 GO:0051179 localization
1.43 2.15e-02 GO:0046578 regulation of Ras protein signal transduction
1.32 2.18e-02 GO:0023057 negative regulation of signaling
1.33 2.27e-02 GO:0032583 regulation of gene-specific transcription
1.33 2.27e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.64 2.58e-02 GO:0035023 regulation of Rho protein signal transduction
1.31 3.26e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.23 3.54e-02 GO:0051128 regulation of cellular component organization
1.54 3.62e-02 GO:0060562 epithelial tube morphogenesis
1.25 4.48e-02 GO:0009790 embryo development
1.39 4.51e-02 GO:0001944 vasculature development
1.17 4.80e-02 GO:0065009 regulation of molecular function
1.47 4.95e-02 GO:0032582 negative regulation of gene-specific transcription
1.53 4.98e-02 GO:0031344 regulation of cell projection organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 2.63e-15 GO:0005737 cytoplasm
1.07 5.27e-15 GO:0005622 intracellular
1.07 9.95e-14 GO:0044424 intracellular part
1.07 6.10e-08 GO:0043227 membrane-bounded organelle
1.07 6.14e-08 GO:0043226 organelle
1.07 7.57e-08 GO:0043231 intracellular membrane-bounded organelle
1.07 8.90e-08 GO:0043229 intracellular organelle
1.10 1.37e-07 GO:0044444 cytoplasmic part
1.09 4.94e-05 GO:0005634 nucleus
1.03 9.71e-05 GO:0005623 cell
1.02 1.16e-04 GO:0044464 cell part
1.16 1.18e-04 GO:0005829 cytosol
1.43 2.50e-04 GO:0044456 synapse part
1.37 3.09e-04 GO:0045202 synapse
1.58 7.20e-04 GO:0005912 adherens junction
1.29 1.00e-03 GO:0030054 cell junction
1.17 1.24e-03 GO:0012505 endomembrane system
1.54 1.27e-03 GO:0070161 anchoring junction
1.95 1.24e-02 GO:0030672 synaptic vesicle membrane
1.62 1.65e-02 GO:0005925 focal adhesion
1.28 1.90e-02 GO:0000139 Golgi membrane
1.35 1.92e-02 GO:0015629 actin cytoskeleton
1.19 2.21e-02 GO:0005794 Golgi apparatus
1.65 2.36e-02 GO:0008021 synaptic vesicle
1.24 3.00e-02 GO:0044431 Golgi apparatus part
1.57 4.25e-02 GO:0005924 cell-substrate adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.10 2.78e-09 GO:0005515 protein binding
1.05 2.24e-08 GO:0005488 binding
1.45 1.69e-07 GO:0019904 protein domain specific binding
1.27 1.06e-05 GO:0030234 enzyme regulator activity
1.39 1.21e-05 GO:0060589 nucleoside-triphosphatase regulator activity
1.39 1.44e-05 GO:0030695 GTPase regulator activity
1.58 7.29e-04 GO:0005085 guanyl-nucleotide exchange factor activity
1.20 1.07e-02 GO:0001071 nucleic acid binding transcription factor activity
1.20 1.07e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.35 2.50e-02 GO:0016563 transcription activator activity
1.20 3.19e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.23 3.32e-02 GO:0043565 sequence-specific DNA binding
1.62 3.56e-02 GO:0016566 specific transcriptional repressor activity
1.19 4.21e-02 GO:0030528 transcription regulator activity
1.35 5.00e-02 GO:0005083 small GTPase regulator activity