• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: REST.p3

Z-value: 1.734

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_-_3472245	6.402		LOC100129223	hypothetical LOC100129223
chr3_+_62279707	4.557		C3orf14	chromosome 3 open reading frame 14
chr10_+_99599984	4.504	NM_001010917	GOLGA7B	golgin A7 family, member B
chr1_+_208178160	4.270	NM_001146261 NM_001146262 NM_001146264 NM_153262	SYT14	synaptotagmin XIV
chr1_+_208178198	4.270		SYT14	synaptotagmin XIV
chr7_-_19778928	4.052	NM_152774	TMEM196	transmembrane protein 196
chr3_-_133236447	3.998	NM_130808	CPNE4	copine IV
chr3_+_9720509	3.878	NM_153635	CPNE9	copine family member IX
chr20_+_61798512	3.835		TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy
chr9_-_73251639	3.535		TRPM3	transient receptor potential cation channel, subfamily M, member 3
chr20_+_61798446	3.109	NM_003823	TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy
chr3_+_62280435	2.911	NM_020685	C3orf14	chromosome 3 open reading frame 14
chr12_-_29827952	2.898	NM_001193451	TMTC1	transmembrane and tetratricopeptide repeat containing 1
chr5_+_33972247	2.874	NM_016568	RXFP3	relaxin/insulin-like family peptide receptor 3
chr15_+_65904994	2.633	NM_001031807	SKOR1	SKI family transcriptional corepressor 1
chr17_+_39741306	2.570	NM_001144825 NM_001144826 NM_006695	RUNDC3A	RUN domain containing 3A
chr4_+_158361185	2.504	NM_000826 NM_001083619 NM_001083620	GRIA2	glutamate receptor, ionotropic, AMPA 2
chr14_-_50631407	2.481		TRIM9	tripartite motif containing 9
chr12_-_29828958	2.434	NM_175861	TMTC1	transmembrane and tetratricopeptide repeat containing 1
chr1_-_23393808	2.177	NM_000864	HTR1D	5-hydroxytryptamine (serotonin) receptor 1D
chr14_-_50631794	2.078		TRIM9	tripartite motif containing 9
chr16_+_66244314	1.947		RLTPR	RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr3_-_48675321	1.885	NM_001407	CELSR3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr1_+_152806874	1.866	NM_000748	CHRNB2	cholinergic receptor, nicotinic, beta 2 (neuronal)
chr15_-_81175542	1.774	NM_004644	AP3B2	adaptor-related protein complex 3, beta 2 subunit
chr1_+_152806924	1.754		CHRNB2	cholinergic receptor, nicotinic, beta 2 (neuronal)
chr1_-_207892420	1.751	NM_000228	LAMB3	laminin, beta 3
chr12_+_46133	1.633	NM_001170738	IQSEC3	IQ motif and Sec7 domain 3
chr7_+_154943466	1.624	NM_001427	EN2	engrailed homeobox 2
chr7_-_100595552	1.591	NM_003378	VGF	VGF nerve growth factor inducible
chr6_+_158877455	1.590	NM_020823	TMEM181	transmembrane protein 181
chr20_+_5839973	1.506	NM_001819	CHGB	chromogranin B (secretogranin 1)
chr11_-_123030091	1.385		SCN3B	sodium channel, voltage-gated, type III, beta
chr8_-_57521065	1.294	NM_006211	PENK	proenkephalin
chr6_+_158877640	1.239		TMEM181	transmembrane protein 181
chr11_-_1725924	1.232	NM_001170820	LOC402778	CD225 family protein FLJ76511
chr10_+_60607232	1.119	NM_001143774	PHYHIPL	phytanoyl-CoA 2-hydroxylase interacting protein-like
chr15_+_67009892	1.075	NM_145658 NM_001184780	SPESP1 NOX5	sperm equatorial segment protein 1 NADPH oxidase, EF-hand calcium binding domain 5
chr11_-_1725662	1.062		LOC402778	CD225 family protein FLJ76511
chr5_-_175969697	1.049	NM_052899	GPRIN1	G protein regulated inducer of neurite outgrowth 1
chr8_+_57520915	0.998
chr11_-_74819165	0.969	NM_001039548	KLHL35	kelch-like 35 (Drosophila)
chr14_+_92459197	0.937	NM_001275	CHGA	chromogranin A (parathyroid secretory protein 1)
chr16_+_4948318	0.907	NM_014692	SEC14L5	SEC14-like 5 (S. cerevisiae)
chr2_+_207215386	0.882	NM_001102659	LOC200726	hCG1657980
chr11_-_122357545	0.875	NM_001098169	BSX	brain-specific homeobox
chr11_+_45863774	0.875	NM_005456	MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1
chr14_+_92459244	0.824		CHGA	chromogranin A (parathyroid secretory protein 1)
chr6_+_25760352	0.795	NM_006998	SCGN	secretagogin, EF-hand calcium binding protein
chr20_-_61755145	0.791	NM_015894	STMN3	stathmin-like 3
chr2_+_131230252	0.764	NM_001105194 NM_001105195	FAM123C	family with sequence similarity 123C
chr9_+_134447795	0.763	NM_020064	BARHL1	BarH-like homeobox 1
chr15_-_70399181	0.757		CELF6	CUGBP, Elav-like family member 6
chr11_+_62136788	0.757	NM_000327	ROM1	retinal outer segment membrane protein 1
chr18_-_39111243	0.729	NM_020783	SYT4	synaptotagmin IV
chr17_-_3283884	0.726	NM_003554	OR1E2	olfactory receptor, family 1, subfamily E, member 2
chr8_-_91164100	0.703	NM_004929	CALB1	calbindin 1, 28kDa
chr11_-_27677755	0.695	NM_170734	BDNF	brain-derived neurotrophic factor
chr16_+_2959342	0.694	NM_152341	PAQR4	progestin and adipoQ receptor family member IV
chr15_-_70399301	0.691	NM_001172684	CELF6	CUGBP, Elav-like family member 6
chr10_+_89409332	0.687	NM_001015880 NM_004670	PAPSS2	3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr15_+_73074882	0.681	NM_001178111 NM_001178112 NM_138967	SCAMP5	secretory carrier membrane protein 5
chr15_-_70399551	0.677	NM_052840	CELF6	CUGBP, Elav-like family member 6
chr1_-_239587090	0.671	NM_002924	RGS7	regulator of G-protein signaling 7
chr16_+_2959362	0.663		PAQR4	progestin and adipoQ receptor family member IV
chr17_-_37022465	0.648	NM_005557	KRT16	keratin 16
chr11_-_74818685	0.647		KLHL35	kelch-like 35 (Drosophila)
chr10_-_102780840	0.637		PDZD7	PDZ domain containing 7
chr10_-_102780867	0.608	NM_001195263 NM_024895	PDZD7	PDZ domain containing 7
chr10_+_102780974	0.606	NM_030971	SFXN3	sideroflexin 3
chr9_+_139153409	0.594	NM_000832 NM_001185090 NM_001185091 NM_007327 NM_021569	GRIN1	glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr3_-_188870799	0.592	NM_001048	SST	somatostatin
chr2_-_51112743	0.590		NRXN1	neurexin 1
chr11_-_74818858	0.583		KLHL35	kelch-like 35 (Drosophila)
chr15_-_70399523	0.582		CELF6	CUGBP, Elav-like family member 6
chr18_+_55718171	0.552	NM_021127	PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1
chr1_-_102234959	0.547		OLFM3	olfactomedin 3
chr6_+_110406890	0.515	NM_005284	GPR6	G protein-coupled receptor 6
chr17_-_7159094	0.503	NM_004489	GPS2	G protein pathway suppressor 2
chr15_+_92575767	0.498		MCTP2	multiple C2 domains, transmembrane 2
chr2_-_27384617	0.494	NM_003353	UCN	urocortin
chr11_-_125278296	0.490	NM_031307	PUS3	pseudouridylate synthase 3
chr12_+_112280753	0.461	NM_001159727 NM_173542	PLBD2	phospholipase B domain containing 2
chr6_+_154402135	0.445	NM_000914 NM_001008503 NM_001008504 NM_001008505 NM_001145282 NM_001145283 NM_001145285 NM_001145286 NM_001145284	OPRM1	opioid receptor, mu 1
chr4_-_175986952	0.444	NM_001042543 NM_006529	GLRA3	glycine receptor, alpha 3
chr4_+_8633116	0.418	NM_080819	GPR78	G protein-coupled receptor 78
chr12_+_112280757	0.394		PLBD2	phospholipase B domain containing 2
chr10_+_26545599	0.377		GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr1_-_102235377	0.373	NM_058170	OLFM3	olfactomedin 3
chr3_-_115380539	0.363	NM_000796 NM_033663	DRD3	dopamine receptor D3
chr19_-_60383280	0.355	NM_003180	SYT5	synaptotagmin V
chr17_+_27838041	0.334	NM_003885	CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr17_-_77474597	0.322	NM_032711	MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr12_+_6431437	0.295	NM_018009	TAPBPL	TAP binding protein-like
chr2_-_96174502	0.284		DUSP2	dual specificity phosphatase 2
chr1_-_239587007	0.280		RGS7	regulator of G-protein signaling 7
chr9_-_103397023	0.233	NM_147180	PPP3R2	protein phosphatase 3, regulatory subunit B, beta
chr2_+_46377952	0.209	NM_001430	EPAS1	endothelial PAS domain protein 1
chr2_-_96174865	0.199	NM_004418	DUSP2	dual specificity phosphatase 2
chr19_-_45416043	0.186		TTC9B	tetratricopeptide repeat domain 9B
chr11_-_65871592	0.145	NM_006876	B3GNT1	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr5_+_141283550	0.134	NM_001142603 NM_014773	KIAA0141	KIAA0141
chr1_+_100777044	0.127		GPR88	G protein-coupled receptor 88
chr17_+_77925441	0.123	NM_018949	UTS2R	urotensin 2 receptor
chr2_-_51113040	0.117	NM_001135659 NM_004801	NRXN1	neurexin 1
chr19_-_50429306	0.105	NM_138568	EXOC3L2	exocyst complex component 3-like 2
chr21_-_34749908	0.103	NM_001127670	KCNE1	potassium voltage-gated channel, Isk-related family, member 1
chr17_-_3546236	0.101	NM_002561 NM_175080 NM_175081	P2RX5-TAX1BP3 P2RX5	P2RX5-TAX1BP3 read-through transcript purinergic receptor P2X, ligand-gated ion channel, 5
chr5_+_141283647	0.090		KIAA0141	KIAA0141
chr2_-_219791902	0.088	NM_005689	ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr1_-_33108876	0.084	NM_001171940 NM_153756	FNDC5	fibronectin type III domain containing 5
chr22_-_16636748	0.069	NM_197966	BID	BH3 interacting domain death agonist
chr16_+_2450081	0.054	NM_025108	C16orf59	chromosome 16 open reading frame 59
chr10_-_44200458	0.048	NM_000609 NM_001033886 NM_001178134 NM_199168	CXCL12	chemokine (C-X-C motif) ligand 12
chr10_+_69990050	0.042	NM_030625	TET1	tet oncogene 1
chr8_+_11703368	0.040		FDFT1	farnesyl-diphosphate farnesyltransferase 1
chr7_+_145444385	0.039	NM_014141	CNTNAP2	contactin associated protein-like 2
chr8_-_94046891	0.033	NM_001191036	C8orf83	chromosome 8 open reading frame 83
chr1_-_151390050	0.029	NM_001014291	SPRR2G	small proline-rich protein 2G
chr9_-_138236775	0.024	NM_178138	LHX3	LIM homeobox 3
chr22_+_18388656	0.024		C22orf25	chromosome 22 open reading frame 25
chr1_+_33124658	0.022	NM_002143	HPCA	hippocalcin
chr19_+_51804260	0.009		CALM3	calmodulin 3 (phosphorylase kinase, delta)
chr10_+_73225533	0.009	NM_001171933 NM_001171934	CDH23	cadherin-related 23
chr8_-_94047440	0.002	NM_001191035 NM_001171795 NM_001171796 NM_001171797 NM_001171798 NM_001171799	C8orf83	chromosome 8 open reading frame 83

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
5.67	2.53e-05	GO:0007186	G-protein coupled receptor protein signaling pathway
3.19	2.94e-05	GO:0003008	system process
3.52	3.59e-05	GO:0050877	neurological system process
7.19	1.79e-04	GO:0007610	behavior
5.51	3.01e-04	GO:0019226	transmission of nerve impulse
5.51	3.01e-04	GO:0035637	multicellular organismal signaling
1.89	3.63e-04	GO:0032501	multicellular organismal process
5.76	5.39e-04	GO:0006873	cellular ion homeostasis
5.71	5.83e-04	GO:0007268	synaptic transmission
5.56	7.75e-04	GO:0055082	cellular chemical homeostasis
5.31	1.24e-03	GO:0050801	ion homeostasis
4.41	3.54e-03	GO:0048878	chemical homeostasis
4.59	5.57e-03	GO:0019725	cellular homeostasis
1.98	9.43e-03	GO:0023052	signaling
5.57	1.70e-02	GO:0055080	cation homeostasis
7.13	2.88e-02	GO:0055074	calcium ion homeostasis
18.93	2.91e-02	GO:0051899	membrane depolarization
3.59	3.12e-02	GO:0007267	cell-cell signaling
37.84	3.14e-02	GO:0042749	regulation of circadian sleep/wake cycle
37.84	3.14e-02	GO:0045187	regulation of circadian sleep/wake cycle, sleep
6.87	3.63e-02	GO:0072507	divalent inorganic cation homeostasis
5.79	3.67e-02	GO:0055065	metal ion homeostasis
35.48	3.85e-02	GO:0022410	circadian sleep/wake cycle process
3.12	4.02e-02	GO:0007154	cell communication
8.30	4.36e-02	GO:0031644	regulation of neurological system process
33.39	4.66e-02	GO:0042745	circadian sleep/wake cycle

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
6.42	1.20e-05	GO:0043005	neuron projection
3.70	6.06e-04	GO:0042995	cell projection
13.21	6.98e-04	GO:0008021	synaptic vesicle
3.87	1.52e-03	GO:0016023	cytoplasmic membrane-bounded vesicle
3.80	1.87e-03	GO:0031988	membrane-bounded vesicle
5.94	2.32e-03	GO:0044456	synapse part
8.29	2.49e-03	GO:0030136	clathrin-coated vesicle
3.64	2.98e-03	GO:0031410	cytoplasmic vesicle
7.75	3.81e-03	GO:0043025	neuronal cell body
4.90	4.15e-03	GO:0045202	synapse
3.53	4.26e-03	GO:0031982	vesicle
7.53	4.58e-03	GO:0044297	cell body
7.02	7.20e-03	GO:0030425	dendrite
5.85	7.65e-03	GO:0030659	cytoplasmic vesicle membrane
6.77	9.06e-03	GO:0030135	coated vesicle
5.66	9.71e-03	GO:0012506	vesicle membrane
11.14	9.86e-03	GO:0030665	clathrin coated vesicle membrane
16.83	1.05e-02	GO:0030672	synaptic vesicle membrane
4.86	2.76e-02	GO:0044433	cytoplasmic vesicle part
8.24	4.08e-02	GO:0030662	coated vesicle membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
20.14	4.60e-04	GO:0005231	excitatory extracellular ligand-gated ion channel activity
13.15	3.79e-03	GO:0005230	extracellular ligand-gated ion channel activity
3.63	1.05e-02	GO:0005509	calcium ion binding
9.56	1.73e-02	GO:0005179	hormone activity
27.03	1.73e-02	GO:0005184	neuropeptide hormone activity
4.48	1.75e-02	GO:0005216	ion channel activity
4.41	1.97e-02	GO:0022838	substrate-specific channel activity
4.28	2.47e-02	GO:0015267	channel activity
4.27	2.51e-02	GO:0022803	passive transmembrane transporter activity
7.70	4.74e-02	GO:0043176	amine binding
5.03	4.79e-02	GO:0005261	cation channel activity