Motif ID: RORA.p2

Z-value: 0.591


Transcription factors associated with RORA.p2:

Gene SymbolEntrez IDGene Name
RORA 6095 RAR-related orphan receptor A



Activity profile for motif RORA.p2.

activity profile for motif RORA.p2


Sorted Z-values histogram for motif RORA.p2

Sorted Z-values for motif RORA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RORA.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_69725342 1.032 NM_033262
NM_058240
NM_182932
NM_183002
SLC8A3



solute carrier family 8 (sodium/calcium exchanger), member 3



chr1_-_233879617 1.000 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr3_+_185520744 0.784 NM_004953
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr18_+_30327341 0.589 DTNA
dystrobrevin, alpha
chr17_+_68672705 0.573 NM_001050
SSTR2
somatostatin receptor 2
chr6_-_152664906 0.501 SYNE1
spectrin repeat containing, nuclear envelope 1
chr18_-_54447168 0.499 NM_052947
ALPK2
alpha-kinase 2
chr7_+_18501876 0.495 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr14_-_90780604 0.483 NM_001177676
GPR68
G protein-coupled receptor 68
chr14_-_23874083 0.435 NM_001198568
NM_001198592
NM_139247
ADCY4


adenylate cyclase 4


chr18_+_30327243 0.432 NM_001198945
NM_001392
NM_032975
NM_032979
DTNA



dystrobrevin, alpha



chr2_-_154043403 0.416 NM_019845
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr4_+_52612197 0.410 NM_145263
SPATA18
spermatogenesis associated 18 homolog (rat)
chr19_-_53832381 0.392 NM_001352
DBP
D site of albumin promoter (albumin D-box) binding protein
chr3_+_44571600 0.379 NM_018651
NM_025169
ZNF167

zinc finger protein 167

chr2_+_27154938 0.378 NM_007046
EMILIN1
elastin microfibril interfacer 1
chr2_+_219180862 0.357 PLCD4
phospholipase C, delta 4
chr11_+_106967165 0.357 ELMOD1
ELMO/CED-12 domain containing 1
chr2_+_219180821 0.354 PLCD4
phospholipase C, delta 4
chr2_+_219180875 0.345 NM_032726
PLCD4
phospholipase C, delta 4
chr22_+_40286957 0.341 NM_014460
CSDC2
cold shock domain containing C2, RNA binding
chr7_+_120756325 0.320 NM_057168
WNT16
wingless-type MMTV integration site family, member 16
chrX_-_114703273 0.316


chr1_-_171442937 0.300 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr9_+_74110149 0.285


chr11_+_106967283 0.272 ELMOD1
ELMO/CED-12 domain containing 1
chr15_-_50270856 0.267 NM_016194
GNB5
guanine nucleotide binding protein (G protein), beta 5
chr9_-_115877104 0.265 AMBP
alpha-1-microglobulin/bikunin precursor
chr17_-_2250967 0.262 NM_020310
MNT
MAX binding protein
chr10_-_71811353 0.245 NM_207119
LRRC20
leucine rich repeat containing 20
chr15_-_63457378 0.235 NM_004884
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chr11_-_47572478 0.227 NM_031909
C1QTNF4
C1q and tumor necrosis factor related protein 4
chr4_+_155703581 0.220 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr5_+_66160359 0.215 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr1_-_176205970 0.202 SEC16B
SEC16 homolog B (S. cerevisiae)
chr19_+_1220244 0.200 NM_001280
CIRBP
cold inducible RNA binding protein
chr17_-_31332568 0.191 NM_004590
CCL16
chemokine (C-C motif) ligand 16
chr16_+_57091546 0.190 NDRG4
NDRG family member 4
chr10_+_102285690 0.187 HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr1_+_46151845 0.185 MAST2
microtubule associated serine/threonine kinase 2
chr3_-_127382051 0.177 ALDH1L1
aldehyde dehydrogenase 1 family, member L1
chr5_-_154210341 0.176 C5orf4
chromosome 5 open reading frame 4
chrX_+_56772391 0.175 LOC550643
hypothetical LOC550643
chr1_+_20269239 0.173 NM_000929
PLA2G5
phospholipase A2, group V
chr5_-_137099602 0.173 NM_017415
KLHL3
kelch-like 3 (Drosophila)
chr8_-_72436832 0.171 EYA1
eyes absent homolog 1 (Drosophila)
chr10_-_100164877 0.170 NM_032709
PYROXD2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr2_+_170742900 0.167 NM_001083615
NM_001171642
NM_138995
MYO3B


myosin IIIB


chr8_+_120289735 0.163 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr17_-_30414789 0.158 NM_001017368
RFFL
ring finger and FYVE-like domain containing 1
chr10_-_52315390 0.154 A1CF
APOBEC1 complementation factor
chr4_-_186969202 0.153 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr5_+_38294289 0.150 NM_152403
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr10_+_102285562 0.144 NM_017902
HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr10_-_52315436 0.140 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr6_-_52217185 0.140 NM_052872
IL17F
interleukin 17F
chr16_-_21739231 0.138 RRN3P1
RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
chr3_-_50335113 0.138 NM_003773
NM_033158
HYAL2

hyaluronoglucosaminidase 2

chr11_+_109468734 0.138 ZC3H12C
zinc finger CCCH-type containing 12C
chr5_+_38294417 0.132 EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr14_-_89868006 0.131 NM_017970
NM_199043
C14orf102

chromosome 14 open reading frame 102

chr6_-_112033775 0.129 TRAF3IP2
TRAF3 interacting protein 2
chr11_-_6418705 0.129 NM_000613
HPX
hemopexin
chr3_+_9919295 0.129 NM_153483
IL17RE
interleukin 17 receptor E
chr11_+_13255967 0.126 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr2_-_15999154 0.121 MYCNOS
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) opposite strand
chr17_+_7474128 0.120 SHBG
sex hormone-binding globulin
chr1_-_176205672 0.119 NM_033127
SEC16B
SEC16 homolog B (S. cerevisiae)
chr11_+_13255905 0.119 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_55776251 0.118 NM_001004747
OR5T3
olfactory receptor, family 5, subfamily T, member 3
chr3_+_160473784 0.118 SCHIP1
schwannomin interacting protein 1
chr3_-_117647053 0.113 NM_002338
LSAMP
limbic system-associated membrane protein
chr11_+_13255913 0.112 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr16_-_1772305 0.112 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chrX_+_10084984 0.111 NM_001830
CLCN4
chloride channel 4
chr8_-_6407882 0.110 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr12_+_92487728 0.108 NM_003877
SOCS2
suppressor of cytokine signaling 2
chr7_+_151792052 0.106 LOC100128822
hypothetical LOC100128822
chr1_+_176577228 0.104 NM_004841
RASAL2
RAS protein activator like 2
chr1_-_33585848 0.104


chr3_+_142587973 0.102


chr7_-_83662152 0.102 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_+_28637247 0.097 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr11_-_2116048 0.092 IGF2
insulin-like growth factor 2 (somatomedin A)
chr2_+_27358800 0.091 NM_032546
NM_187841
TRIM54

tripartite motif containing 54

chr22_-_31732648 0.090 NM_003490
NM_133633
SYN3

synapsin III

chr11_+_13255948 0.089 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_131285747 0.089 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr11_+_13255836 0.087 NM_001030272
NM_001030273
NM_001178
ARNTL


aryl hydrocarbon receptor nuclear translocator-like


chr4_+_39084867 0.087 NM_175737
KLB
klotho beta
chr17_-_23721430 0.085 VTN
vitronectin
chr3_-_126215069 0.084 HEG1
HEG homolog 1 (zebrafish)
chr4_+_85723080 0.084 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr17_+_7474177 0.082 NM_001040
NM_001146279
NM_001146280
NM_001146281
SHBG



sex hormone-binding globulin



chr2_-_165186232 0.082 GRB14
growth factor receptor-bound protein 14
chr19_+_8384181 0.082 NM_001005415
NM_001005416
NM_016496
MARCH2


membrane-associated ring finger (C3HC4) 2


chr5_-_154210350 0.082 C5orf4
chromosome 5 open reading frame 4
chr8_-_120720200 0.082 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chrX_-_71443725 0.081 NM_001144886
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr13_-_26232777 0.080 NM_005288
GPR12
G protein-coupled receptor 12
chr11_+_13255925 0.080 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_-_102156531 0.079 NM_002425
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr16_-_15095590 0.076 NM_018427
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr6_+_121798443 0.076 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr16_-_88623809 0.074 NM_001214
C16orf3
chromosome 16 open reading frame 3
chr12_+_63958689 0.074 NM_001031679
NM_001193460
NM_198080
MSRB3


methionine sulfoxide reductase B3


chr17_-_17426469 0.072 NM_007169
PEMT
phosphatidylethanolamine N-methyltransferase
chr11_-_119104463 0.071 NM_002855
NM_203285
NM_203286
PVRL1


poliovirus receptor-related 1 (herpesvirus entry mediator C)


chr3_-_127382093 0.070 NM_012190
ALDH1L1
aldehyde dehydrogenase 1 family, member L1
chr14_-_19252330 0.069 NM_001197287
OR11H2
olfactory receptor, family 11, subfamily H, member 2
chr11_-_64283945 0.068 PYGM
phosphorylase, glycogen, muscle
chr3_+_48463117 0.067 ATRIP
ATR interacting protein
chr14_-_34661156 0.067 PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr12_+_2792047 0.066 NM_018463
ITFG2
integrin alpha FG-GAP repeat containing 2
chr11_+_33306652 0.066 HIPK3
homeodomain interacting protein kinase 3
chr19_+_55013315 0.065 NM_030973
MED25
mediator complex subunit 25
chr14_-_22825148 0.062 NM_020834
HOMEZ
homeobox and leucine zipper encoding
chr9_-_41944687 0.061 MGC21881
hypothetical locus MGC21881
chr17_-_32730804 0.061 NM_198837
NM_198838
ACACA

acetyl-CoA carboxylase alpha

chr4_+_110968594 0.057 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr11_+_106967017 0.056 NM_001130037
NM_018712
ELMOD1

ELMO/CED-12 domain containing 1

chr15_-_88095363 0.055 NM_018670
MESP1
mesoderm posterior 1 homolog (mouse)
chr9_+_124321239 0.055 NM_001004452
OR1J4
olfactory receptor, family 1, subfamily J, member 4
chr6_+_26212082 0.055 NM_003542
HIST1H4C
histone cluster 1, H4c
chr5_-_54866126 0.053 NM_003711
NM_176895
RNF138P1
PPAP2A

ring finger protein 138 pseudogene 1
phosphatidic acid phosphatase type 2A

chr3_+_32408346 0.053 CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr12_-_46405477 0.051 NM_001172439
NM_001172440
NM_006025
ENDOU


endonuclease, polyU-specific


chr14_-_74458897 0.050 NM_031464
RPS6KL1
ribosomal protein S6 kinase-like 1
chr17_-_17426416 0.049 PEMT
phosphatidylethanolamine N-methyltransferase
chr2_+_38005875 0.049 NM_001170791
FAM82A1
family with sequence similarity 82, member A1
chr1_-_23376860 0.047 LUZP1
leucine zipper protein 1
chr9_+_119506274 0.047 NM_138554
TLR4
toll-like receptor 4
chr17_-_35774467 0.045 NM_152219
GJD3
gap junction protein, delta 3, 31.9kDa
chrX_-_2892288 0.045 NM_000047
ARSE
arylsulfatase E (chondrodysplasia punctata 1)
chr12_+_63958949 0.045 NM_001193461
MSRB3
methionine sulfoxide reductase B3
chr5_-_150501393 0.044 NM_001193544
ANXA6
annexin A6
chr8_+_17440664 0.044 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr16_-_45735333 0.042 NETO2
neuropilin (NRP) and tolloid (TLL)-like 2
chr11_-_65412409 0.038 NM_004214
NM_198897
FIBP

fibroblast growth factor (acidic) intracellular binding protein

chr17_-_46140015 0.038 NM_052855
ANKRD40
ankyrin repeat domain 40
chr14_+_28311740 0.038 C14orf23
chromosome 14 open reading frame 23
chr14_-_74669864 0.037 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr3_+_48463184 0.037 NM_032166
NM_130384
TREX1
ATRIP

three prime repair exonuclease 1
ATR interacting protein

chr11_+_13255952 0.037 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr14_-_67211081 0.036 NM_006370
VTI1B
vesicle transport through interaction with t-SNAREs homolog 1B (yeast)
chr1_-_35692668 0.036 KIAA0319L
KIAA0319-like
chr8_-_134141586 0.035 NM_006748
SLA
Src-like-adaptor
chr4_+_157044296 0.034 NM_005651
TDO2
tryptophan 2,3-dioxygenase
chr11_-_67028415 0.034 PITPNM1
phosphatidylinositol transfer protein, membrane-associated 1
chr12_+_119617060 0.031


chr17_-_2977594 0.030 NM_003555
OR1G1
olfactory receptor, family 1, subfamily G, member 1
chr12_+_54910086 0.026 NM_173596
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr6_-_24491498 0.025 NM_001195610
DCDC2
doublecortin domain containing 2
chr6_+_32229278 0.025 NM_138717
PPT2
palmitoyl-protein thioesterase 2
chr1_-_246869181 0.025 NM_001001827
OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr4_-_120462705 0.023 NM_000134
FABP2
fatty acid binding protein 2, intestinal
chr15_-_74963246 0.023 NM_020843
SCAPER
S-phase cyclin A-associated protein in the ER
chr2_+_119416214 0.022 NM_006770
MARCO
macrophage receptor with collagenous structure
chr19_-_16111695 0.021


chr2_+_102294393 0.020 NM_016232
IL18R1
IL1RL1
interleukin 18 receptor 1
interleukin 1 receptor-like 1
chr17_-_15495534 0.019 TRIM16
tripartite motif containing 16
chr3_-_185578621 0.019 NM_000460
NM_001177597
NM_001177598
THPO


thrombopoietin


chr2_+_232951487 0.019 NM_001632
ALPP
alkaline phosphatase, placental
chr10_-_121286034 0.018 NM_002925
RGS10
regulator of G-protein signaling 10
chr2_+_138975946 0.017


chr14_-_22825072 0.017 HOMEZ
homeobox and leucine zipper encoding
chr3_-_123716454 0.017 KPNA1
karyopherin alpha 1 (importin alpha 5)
chr11_+_2116486 0.017


chr2_-_228206045 0.017 NM_001162483
NM_020161
C2orf83

chromosome 2 open reading frame 83

chr3_-_123716471 0.016 NM_002264
KPNA1
karyopherin alpha 1 (importin alpha 5)
chr14_+_19598043 0.016 NM_001004717
OR4L1
olfactory receptor, family 4, subfamily L, member 1
chr2_-_191580567 0.016 STAT1
signal transducer and activator of transcription 1, 91kDa
chr11_-_2116775 0.016 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr6_+_43845875 0.015 VEGFA
vascular endothelial growth factor A
chr14_-_91268136 0.014 NM_024764
CATSPERB
cation channel, sperm-associated, beta
chrX_-_33139349 0.013 NM_004006
DMD
dystrophin
chr2_-_215711313 0.013 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr9_+_66293049 0.013 MGC21881
hypothetical locus MGC21881
chr1_-_103269356 0.013 COL11A1
collagen, type XI, alpha 1
chr1_-_246880807 0.013 NM_001001824
OR2T27
olfactory receptor, family 2, subfamily T, member 27
chr6_-_155677303 0.011 NM_016020
TFB1M
transcription factor B1, mitochondrial
chr9_-_138462384 0.011 SEC16A
SEC16 homolog A (S. cerevisiae)
chr8_+_124849923 0.010 NM_144963
FAM91A1
family with sequence similarity 91, member A1
chr5_+_38294613 0.009


chr1_+_149877955 0.009 SNX27
sorting nexin family member 27
chr11_+_55617328 0.009 NM_001003750
OR8I2
olfactory receptor, family 8, subfamily I, member 2
chr8_+_36760999 0.007 NM_001031836
KCNU1
potassium channel, subfamily U, member 1
chr11_-_128567302 0.007 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr19_+_62483606 0.007 NM_006635
ZNF460
zinc finger protein 460
chr19_+_63053031 0.007 NM_032828
ZNF587
zinc finger protein 587
chr6_+_42991704 0.007 NM_138296
PTCRA
pre T-cell antigen receptor alpha
chr20_-_1257782 0.005 SDCBP2
syndecan binding protein (syntenin) 2
chr5_+_81636921 0.005 NM_001017971
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr12_+_53534565 0.004 NM_058173
MUCL1
mucin-like 1
chr5_-_134942867 0.004 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chr5_+_147695314 0.003 NM_001040433
SPINK9
serine peptidase inhibitor, Kazal type 9
chr8_-_142307854 0.003 NM_001080431
SLC45A4
solute carrier family 45, member 4
chr6_-_155677254 0.003 TFB1M
transcription factor B1, mitochondrial
chrX_+_150635162 0.002 NM_033085
FATE1
fetal and adult testis expressed 1
chr19_+_8814268 0.002 NM_145208
MBD3L1
methyl-CpG binding domain protein 3-like 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.87 3.97e-02 GO:0060089 molecular transducer activity