Motif ID: RREB1.p2

Z-value: 2.737


Transcription factors associated with RREB1.p2:

Gene SymbolEntrez IDGene Name
RREB1 6239 ras responsive element binding protein 1



Activity profile for motif RREB1.p2.

activity profile for motif RREB1.p2


Sorted Z-values histogram for motif RREB1.p2

Sorted Z-values for motif RREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RREB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_30977931 4.937 LAPTM5
lysosomal protein transmembrane 5
chrX_+_151617900 4.043 NM_005363
NM_175868
MAGEA6

melanoma antigen family A, 6

chrX_-_151688850 3.394 NM_005362
MAGEA3
melanoma antigen family A, 3
chrX_+_151633730 3.097 NM_005361
NM_175742
NM_175743
MAGEA2


melanoma antigen family A, 2


chr2_-_96924582 3.044 NM_001172667
FAM178B
family with sequence similarity 178, member B
chrX_-_151653756 2.941 NM_001166386
NM_001166387
NM_005367
MAGEA12


melanoma antigen family A, 12


chr3_+_187917791 2.660 NM_000893
NM_001102416
NM_001166451
KNG1


kininogen 1


chrX_-_151672985 2.595 NM_005361
NM_175742
NM_175743
MAGEA2


melanoma antigen family A, 2


chrX_-_152139267 2.590 NM_004988
MAGEA1
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chrX_+_151653874 2.457 NM_001102576
NM_153478
CSAG1

chondrosarcoma associated gene 1

chr19_+_3317575 2.172 NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr11_-_74740298 2.159 NM_004041
NM_020251
ARRB1

arrestin, beta 1

chr1_+_945331 2.152 NM_198576
AGRN
agrin
chr12_+_54700955 2.139 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr19_+_3317589 2.070 NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr19_+_60487578 1.976 BRSK1
BR serine/threonine kinase 1
chrX_-_148476903 1.931 NM_005365
NM_001080790
MAGEA9
MAGEA9B
melanoma antigen family A, 9
melanoma antigen family A, 9B
chr10_-_135000464 1.845 NM_015722
CALY
calcyon neuron-specific vesicular protein
chr8_+_144706699 1.798 NM_001166237
GSDMD
gasdermin D
chr19_+_3317536 1.742 NM_005597
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr22_-_21231421 1.674 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr14_+_104244998 1.653 INF2
inverted formin, FH2 and WH2 domain containing
chr7_-_100331417 1.649 NM_000665
NM_015831
ACHE

acetylcholinesterase

chrX_+_150832016 1.621 NM_001011548
MAGEA4
melanoma antigen family A, 4
chr1_-_1283770 1.621 NM_032348
MXRA8
matrix-remodelling associated 8
chr20_-_55533544 1.592 NM_080618
CTCFL
CCCTC-binding factor (zinc finger protein)-like
chr1_+_945399 1.576


chr21_-_46428728 1.536 C21orf56
chromosome 21 open reading frame 56
chr20_+_48032918 1.527 NM_005985
SNAI1
snail homolog 1 (Drosophila)
chr19_+_17723285 1.512 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr19_+_60487345 1.504 NM_032430
BRSK1
BR serine/threonine kinase 1
chr6_-_31668476 1.480 NM_001145466
NM_001145467
NM_147130
NCR3


natural cytotoxicity triggering receptor 3


chr21_-_46428768 1.472 C21orf56
chromosome 21 open reading frame 56
chr7_-_100077072 1.454 NM_003227
TFR2
transferrin receptor 2
chr10_-_135000358 1.443 CALY
calcyon neuron-specific vesicular protein
chr9_-_122679283 1.416 PHF19
PHD finger protein 19
chr7_-_150305933 1.391 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr8_-_73150371 1.387 NM_007332
TRPA1
transient receptor potential cation channel, subfamily A, member 1
chr22_+_19699441 1.365 NM_001159554
NM_005446
P2RX6

purinergic receptor P2X, ligand-gated ion channel, 6

chr9_-_122679387 1.343 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chrX_-_119133802 1.289 NM_139282
RHOXF1
Rhox homeobox family, member 1
chr12_+_56135353 1.286 NM_031479
INHBE
inhibin, beta E
chr12_-_52980984 1.286 NM_001136023
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chrX_+_148671394 1.264 NM_005365
NM_001080790
MAGEA9
MAGEA9B
melanoma antigen family A, 9
melanoma antigen family A, 9B
chr19_+_811615 1.263 CFD
complement factor D (adipsin)
chr19_+_14405216 1.260 PKN1
protein kinase N1
chr3_-_185578621 1.252 NM_000460
NM_001177597
NM_001177598
THPO


thrombopoietin


chr21_-_46428788 1.245 NM_001142854
NM_032261
C21orf56

chromosome 21 open reading frame 56

chr12_-_52980914 1.210 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr19_+_14405100 1.197 NM_002741
PKN1
protein kinase N1
chr19_-_60350122 1.193 TNNT1
troponin T type 1 (skeletal, slow)
chr13_-_113066366 1.172 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chrX_+_152561086 1.164 NM_001395
DUSP9
dual specificity phosphatase 9
chr20_-_62151216 1.136 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr16_-_28515868 1.125 NM_001054
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr10_-_76538859 1.099 NM_001007271
NM_001007272
NM_001007273
DUSP13


dual specificity phosphatase 13


chr21_-_43369492 1.096 NM_001178008
NM_001178009
CBS

cystathionine-beta-synthase

chr7_+_150390566 1.059 SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr10_+_45189617 1.053 NM_000698
ALOX5
arachidonate 5-lipoxygenase
chr11_+_56984702 1.050 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr19_-_6453224 1.043 NM_006087
TUBB4
tubulin, beta 4
chr5_+_76181581 1.031 NM_130772
S100Z
S100 calcium binding protein Z
chr20_-_49592444 1.021 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr4_+_191235959 1.017 NM_001177376
DUX4L4
double homeobox 4 like 4
chr5_-_138746840 1.013 SLC23A1
solute carrier family 23 (nucleobase transporters), member 1
chr1_-_200397300 1.012 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr8_-_145119627 1.011 NM_201378
PLEC
plectin
chr7_-_150306169 1.001 KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr19_+_12805747 0.995 MAST1
microtubule associated serine/threonine kinase 1
chr5_-_138746917 0.986 NM_005847
NM_152685
SLC23A1

solute carrier family 23 (nucleobase transporters), member 1

chr11_+_57121602 0.976 NM_000062
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr14_+_104267270 0.974 NM_199165
ADSSL1
adenylosuccinate synthase like 1
chr17_-_39700960 0.972 NM_000342
SLC4A1
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)
chr12_+_6807831 0.961 NM_014262
LEPREL2
leprecan-like 2
chrX_-_11194015 0.953 NM_013423
ARHGAP6
Rho GTPase activating protein 6
chr1_-_149214063 0.952 NM_022075
NM_181746
LASS2

LAG1 homolog, ceramide synthase 2

chr7_+_134567270 0.951 NM_182489
STRA8
stimulated by retinoic acid gene 8 homolog (mouse)
chr6_-_86409369 0.942 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr21_-_43368963 0.929 NM_000071
CBS
cystathionine-beta-synthase
chr11_+_10434056 0.929 NM_001025390
AMPD3
adenosine monophosphate deaminase 3
chr7_+_128219307 0.928 NM_022742
CCDC136
coiled-coil domain containing 136
chr7_+_74017015 0.924 NM_001145063
GATSL1
GATSL2
GATS protein-like 1
GATS protein-like 2
chr2_-_174537354 0.920 SP3
Sp3 transcription factor
chr19_-_7896974 0.916 NM_206833
CTXN1
cortexin 1
chr11_+_10433241 0.915 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr12_-_21818881 0.911 NM_004982
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr9_+_138760432 0.899 LOC100128593
hypothetical LOC100128593
chr16_-_65516919 0.899 NM_001128850
NM_004165
RRAD

Ras-related associated with diabetes

chr17_-_77474597 0.897 NM_032711
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr1_+_12046020 0.877 NM_001243
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr11_-_57173823 0.874 NM_145008
YPEL4
yippee-like 4 (Drosophila)
chr20_-_61574259 0.868 NM_004518
NM_172106
NM_172107
NM_172108
NM_172109
KCNQ2




potassium voltage-gated channel, KQT-like subfamily, member 2




chr20_-_22513050 0.865 NM_021784
FOXA2
forkhead box A2
chrX_-_153534951 0.864 NM_020994
NM_172377
CTAG2

cancer/testis antigen 2

chr12_-_53071285 0.863 NM_001130967
NM_001130968
ZNF385A

zinc finger protein 385A

chr10_+_45189673 0.860 ALOX5
arachidonate 5-lipoxygenase
chr7_-_148212336 0.860 NM_004456
NM_152998
EZH2

enhancer of zeste homolog 2 (Drosophila)

chr14_-_20563698 0.855 NDRG2
NDRG family member 2
chr13_-_113066202 0.850 GRTP1
growth hormone regulated TBC protein 1
chr6_-_86409415 0.848 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr1_+_110012166 0.845 NM_000848
NM_001142368
GSTM2

glutathione S-transferase mu 2 (muscle)

chr15_+_41597097 0.843 NM_002373
MAP1A
microtubule-associated protein 1A
chr12_-_56157898 0.840 NM_001080156
ARHGAP9
Rho GTPase activating protein 9
chr10_-_126839000 0.839 CTBP2
C-terminal binding protein 2
chr19_-_60350118 0.828 TNNT1
troponin T type 1 (skeletal, slow)
chr19_-_34897802 0.815 NM_001031726
C19orf12
chromosome 19 open reading frame 12
chr14_-_20563722 0.814 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr17_-_71352090 0.813 UNC13D
unc-13 homolog D (C. elegans)
chr16_+_84202515 0.811 NM_001134473
KIAA0182
KIAA0182
chrX_+_119176494 0.811 NM_001099685
NM_032498
RHOXF2B
RHOXF2
Rhox homeobox family, member 2B
Rhox homeobox family, member 2
chr4_-_2906256 0.807 MFSD10
major facilitator superfamily domain containing 10
chr16_+_665680 0.804 RHBDL1
rhomboid, veinlet-like 1 (Drosophila)
chr20_-_22512893 0.797 FOXA2
forkhead box A2
chr6_+_32230172 0.787 PPT2
palmitoyl-protein thioesterase 2
chr21_-_10120690 0.787 NM_001187
NM_182484
NM_181704
NM_182481
NM_182482
BAGE
BAGE5
BAGE4
BAGE3
BAGE2
B melanoma antigen
B melanoma antigen family, member 5
B melanoma antigen family, member 4
B melanoma antigen family, member 3
B melanoma antigen family, member 2
chr2_-_219881937 0.785 PTPRN
protein tyrosine phosphatase, receptor type, N
chr7_-_148212310 0.784 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr7_-_148212312 0.782 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr4_+_191229360 0.779 NM_033178
NM_012147
NM_001177376
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr12_+_46133 0.777 NM_001170738
IQSEC3
IQ motif and Sec7 domain 3
chr17_-_44058612 0.769 NM_024017
HOXB9
homeobox B9
chr6_+_33495824 0.768 NM_006772
SYNGAP1
synaptic Ras GTPase activating protein 1
chr7_-_148212292 0.767 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr1_-_27802688 0.765 NM_001029882
AHDC1
AT hook, DNA binding motif, containing 1
chr1_+_199259664 0.760


chr6_-_43531193 0.759 NM_023932
DLK2
delta-like 2 homolog (Drosophila)
chr17_+_1580504 0.759 WDR81
WD repeat domain 81
chr19_+_48776598 0.754 LOC390940
hypothetical protein LOC390940
chr6_+_32229771 0.754 PPT2-EGFL8
PPT2
PPT2-EGFL8 read-through transcript
palmitoyl-protein thioesterase 2
chr7_+_100792841 0.747 NM_133457
EMID2
EMI domain containing 2
chr10_-_75085754 0.745 NM_001114133
SYNPO2L
synaptopodin 2-like
chr19_-_47498768 0.744 NM_001145939
NM_001145940
PAFAH1B3

platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)

chr7_+_733182 0.744 HEATR2
HEAT repeat containing 2
chr16_+_387176 0.740 NM_005009
NME4
non-metastatic cells 4, protein expressed in
chr10_-_98935652 0.739 NM_003061
SLIT1
slit homolog 1 (Drosophila)
chr10_+_135330357 0.739 NM_033178
NM_012147
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr1_+_945472 0.738 AGRN
agrin
chr19_+_6723801 0.736


chr2_+_42128521 0.735 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr14_+_28305922 0.733 NM_005249
FOXG1
forkhead box G1
chr12_-_54387732 0.732 ITGA7
integrin, alpha 7
chr11_+_46359821 0.732 MDK
midkine (neurite growth-promoting factor 2)
chr19_-_8581559 0.732 NM_030957
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr9_-_129699389 0.729 ST6GALNAC6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr3_-_187025438 0.728 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr7_-_74705276 0.726 NM_001145064
GATSL2
GATS protein-like 2
chr6_+_34541827 0.724 NM_020804
PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr8_+_41804946 0.723


chr6_-_29703725 0.721 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr11_+_2279932 0.720 TSPAN32
tetraspanin 32
chr6_-_32184975 0.718 NM_019105
TNXB
tenascin XB
chrX_-_119095544 0.717 NM_001099685
NM_032498
RHOXF2B
RHOXF2
Rhox homeobox family, member 2B
Rhox homeobox family, member 2
chr16_+_2807228 0.717 PRSS21
protease, serine, 21 (testisin)
chr1_+_21708428 0.715 NM_000478
NM_001127501
NM_001177520
ALPL


alkaline phosphatase, liver/bone/kidney


chr15_+_74416156 0.711 NM_145805
ISL2
ISL LIM homeobox 2
chr19_+_48776535 0.710 NM_001193622
LOC390940
hypothetical protein LOC390940
chr11_-_64268841 0.705 NM_001098670
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr15_-_41300488 0.705 EPB42
erythrocyte membrane protein band 4.2
chr16_-_28528780 0.705 NM_001055
NM_177529
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr1_-_182273114 0.700 GLT25D2
glycosyltransferase 25 domain containing 2
chr17_-_74361975 0.699 TIMP2
TIMP metallopeptidase inhibitor 2
chr22_+_49333327 0.693 NM_138433
KLHDC7B
kelch domain containing 7B
chr2_-_220144511 0.692 NM_001173408
NM_001173431
NM_015311
OBSL1


obscurin-like 1


chr15_-_81037554 0.691 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr2_-_130603264 0.691 NM_001099771
POTEF
POTE ankyrin domain family, member F
chr17_+_16259812 0.690 TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr6_+_7052798 0.684 NM_001168344
RREB1
ras responsive element binding protein 1
chr6_+_38798529 0.678 NM_001371
DNAH8
dynein, axonemal, heavy chain 8
chr1_+_1066138 0.678


chr3_-_159306214 0.678


chr11_+_2279812 0.675 NM_139022
TSPAN32
tetraspanin 32
chr4_-_109308893 0.674 NM_001130713
NM_001130714
NM_016269
LEF1


lymphoid enhancer-binding factor 1


chr12_-_131816604 0.672 ANKLE2
ankyrin repeat and LEM domain containing 2
chr19_+_40451842 0.670 USF2
upstream transcription factor 2, c-fos interacting
chr21_+_41663853 0.663 MX2
myxovirus (influenza virus) resistance 2 (mouse)
chr8_+_144888275 0.662 LOC100128338
hypothetical LOC100128338
chr10_+_135333667 0.659 NM_033178
NM_012147
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr11_-_289518 0.659 NM_001025295
IFITM5
interferon induced transmembrane protein 5
chr17_-_73636362 0.658 TMC6
transmembrane channel-like 6
chr5_+_139008091 0.657 CXXC5
CXXC finger protein 5
chr17_-_73636386 0.657 NM_001127198
TMC6
transmembrane channel-like 6
chr7_-_150411345 0.656 NM_031434
TMUB1
transmembrane and ubiquitin-like domain containing 1
chr13_-_40138607 0.655 NM_002015
FOXO1
forkhead box O1
chr17_+_1595012 0.653 SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr1_-_1525309 0.652 LOC643988
hypothetical LOC643988
chr11_+_46359855 0.650 MDK
midkine (neurite growth-promoting factor 2)
chr19_-_55763091 0.649 NM_001080457
LRRC4B
leucine rich repeat containing 4B
chr11_-_2279642 0.649 NM_001142946
C11orf21
chromosome 11 open reading frame 21
chr11_+_46359836 0.647 MDK
midkine (neurite growth-promoting factor 2)
chr2_-_219882302 0.647 NM_002846
PTPRN
protein tyrosine phosphatase, receptor type, N
chr12_+_56291484 0.645 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chrX_+_117513899 0.645 NM_144658
DOCK11
dedicator of cytokinesis 11
chr1_-_199259133 0.644 KIF21B
kinesin family member 21B
chr3_-_187025501 0.642 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr1_+_20385164 0.639 NM_152376
UBXN10
UBX domain protein 10
chr5_+_139008139 0.639 CXXC5
CXXC finger protein 5
chr5_-_176833197 0.639 DBN1
drebrin 1
chr12_+_95112385 0.638 ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr6_+_14032655 0.638 NM_001165034
RNF182
ring finger protein 182
chr1_-_148155986 0.632 NM_014849
SV2A
synaptic vesicle glycoprotein 2A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.16 6.46e-16 GO:0065007 biological regulation
1.16 4.15e-13 GO:0050789 regulation of biological process
1.15 1.98e-11 GO:0050794 regulation of cellular process
1.47 5.82e-09 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.22 1.12e-08 GO:0031323 regulation of cellular metabolic process
1.22 4.38e-08 GO:0080090 regulation of primary metabolic process
1.20 5.91e-08 GO:0019222 regulation of metabolic process
1.74 1.74e-07 GO:0016568 chromatin modification
1.24 2.95e-07 GO:0051171 regulation of nitrogen compound metabolic process
1.27 3.23e-07 GO:0051252 regulation of RNA metabolic process
1.24 3.47e-07 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21 5.33e-07 GO:0060255 regulation of macromolecule metabolic process
1.07 6.22e-07 GO:0009987 cellular process
1.24 6.84e-07 GO:0048518 positive regulation of biological process
1.23 5.23e-06 GO:0010468 regulation of gene expression
1.24 8.73e-06 GO:0048522 positive regulation of cellular process
1.22 9.21e-06 GO:0031326 regulation of cellular biosynthetic process
1.22 1.29e-05 GO:0009889 regulation of biosynthetic process
1.25 1.84e-05 GO:0048523 negative regulation of cellular process
1.24 2.63e-05 GO:0006355 regulation of transcription, DNA-dependent
1.23 4.42e-05 GO:0048519 negative regulation of biological process
1.22 7.92e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.45 9.81e-05 GO:0051254 positive regulation of RNA metabolic process
1.45 1.27e-04 GO:0010628 positive regulation of gene expression
1.53 1.54e-04 GO:0006325 chromatin organization
1.21 1.99e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.33 2.20e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.31 2.34e-04 GO:0009893 positive regulation of metabolic process
1.39 7.06e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.39 7.42e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.31 8.17e-04 GO:0031325 positive regulation of cellular metabolic process
1.57 1.11e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.43 1.20e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.49 1.39e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.15 1.41e-03 GO:0023052 signaling
1.36 1.43e-03 GO:0009891 positive regulation of biosynthetic process
1.38 1.87e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.53 2.05e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.36 2.10e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.15 6.74e-03 GO:0007275 multicellular organismal development
1.74 7.47e-03 GO:0016569 covalent chromatin modification
1.14 8.11e-03 GO:0032502 developmental process
1.10 9.06e-03 GO:0044238 primary metabolic process
1.42 1.03e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.20 1.20e-02 GO:0065008 regulation of biological quality
1.32 1.21e-02 GO:0022008 neurogenesis
1.24 1.26e-02 GO:0007399 nervous system development
1.42 1.29e-02 GO:0051253 negative regulation of RNA metabolic process
1.32 1.58e-02 GO:0006351 transcription, DNA-dependent
1.32 1.72e-02 GO:0048699 generation of neurons
1.43 1.79e-02 GO:0019226 transmission of nerve impulse
1.43 1.79e-02 GO:0035637 multicellular organismal signaling
1.46 1.85e-02 GO:0032583 regulation of gene-specific transcription
1.72 1.89e-02 GO:0016570 histone modification
1.38 2.15e-02 GO:0051276 chromosome organization
1.36 2.22e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.12 2.50e-02 GO:0044260 cellular macromolecule metabolic process
1.45 2.75e-02 GO:0007268 synaptic transmission
1.36 3.08e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.13 3.57e-02 GO:0051716 cellular response to stimulus
1.35 3.59e-02 GO:0009890 negative regulation of biosynthetic process
1.09 3.81e-02 GO:0044237 cellular metabolic process
1.37 4.06e-02 GO:0010629 negative regulation of gene expression
1.34 4.40e-02 GO:0030182 neuron differentiation
1.30 4.49e-02 GO:0031324 negative regulation of cellular metabolic process
1.36 4.73e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 1.27e-08 GO:0005634 nucleus
1.07 1.30e-08 GO:0044424 intracellular part
1.07 6.32e-08 GO:0005622 intracellular
1.07 2.64e-05 GO:0043226 organelle
1.07 3.80e-05 GO:0043229 intracellular organelle
1.18 1.55e-04 GO:0043234 protein complex
1.08 3.17e-04 GO:0043227 membrane-bounded organelle
1.08 3.95e-04 GO:0043231 intracellular membrane-bounded organelle
1.20 9.06e-04 GO:0044428 nuclear part
1.20 1.09e-03 GO:0005829 cytosol
1.21 1.45e-03 GO:0031981 nuclear lumen
1.07 1.76e-03 GO:0005737 cytoplasm
2.01 2.08e-03 GO:0005875 microtubule associated complex
1.18 4.69e-03 GO:0043233 organelle lumen
1.13 6.65e-03 GO:0032991 macromolecular complex
1.17 9.22e-03 GO:0031974 membrane-enclosed lumen
1.03 1.11e-02 GO:0044464 cell part
1.03 1.17e-02 GO:0005623 cell
1.16 3.01e-02 GO:0070013 intracellular organelle lumen
1.14 4.42e-02 GO:0043228 non-membrane-bounded organelle
1.14 4.42e-02 GO:0043232 intracellular non-membrane-bounded organelle
3.63 4.83e-02 GO:0042627 chylomicron

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 1.03e-17 GO:0005515 protein binding
1.59 9.93e-11 GO:0043565 sequence-specific DNA binding
1.43 2.86e-08 GO:0001071 nucleic acid binding transcription factor activity
1.43 2.86e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
1.39 6.88e-07 GO:0030528 transcription regulator activity
1.06 4.98e-06 GO:0005488 binding
1.21 1.75e-04 GO:0003677 DNA binding
1.57 1.36e-03 GO:0016564 transcription repressor activity
1.71 2.56e-03 GO:0003682 chromatin binding
1.68 2.74e-03 GO:0000975 regulatory region DNA binding
1.68 2.74e-03 GO:0001067 regulatory region nucleic acid binding
1.68 2.74e-03 GO:0044212 transcription regulatory region DNA binding
1.79 4.26e-03 GO:0003714 transcription corepressor activity
1.48 4.26e-03 GO:0003712 transcription cofactor activity
1.48 4.91e-03 GO:0000988 protein binding transcription factor activity
1.48 4.91e-03 GO:0000989 transcription factor binding transcription factor activity
1.65 1.05e-02 GO:0010843 promoter binding
1.14 1.94e-02 GO:0003676 nucleic acid binding
1.46 4.83e-02 GO:0003779 actin binding