Motif ID: SPIB.p2

Z-value: 4.481


Transcription factors associated with SPIB.p2:

Gene SymbolEntrez IDGene Name
SPIB 6689 Spi-B transcription factor (Spi-1/PU.1 related)



Activity profile for motif SPIB.p2.

activity profile for motif SPIB.p2


Sorted Z-values histogram for motif SPIB.p2

Sorted Z-values for motif SPIB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPIB.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_44643067 10.247 ABI3
ABI family, member 3
chr17_-_40843530 9.542 ARHGAP27
Rho GTPase activating protein 27
chr11_+_63864263 7.789 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr4_+_91035025 7.226 NM_007351
MMRN1
multimerin 1
chr12_-_15005761 6.678 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr17_-_44642934 6.359 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr2_-_175207521 6.064 NM_003387
WIPF1
WAS/WASL interacting protein family, member 1
chr6_-_11490487 5.909 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr5_+_61910318 5.778 NM_181506
LRRC70
leucine rich repeat containing 70
chr6_-_32268267 5.421 GPSM3
G-protein signaling modulator 3
chrX_+_48427137 5.307 WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr7_+_106293112 5.260 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr7_+_149778815 5.112 GIMAP8
GTPase, IMAP family member 8
chrX_+_48427103 4.933 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr19_+_3129735 4.857 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chr18_-_65766068 4.846 CD226
CD226 molecule
chr19_-_40925151 4.820 NM_024660
TMEM149
transmembrane protein 149
chr7_+_149778869 4.789 NM_175571
GIMAP8
GTPase, IMAP family member 8
chr17_-_18890963 4.753 NM_006613
GRAP
GRB2-related adaptor protein
chr14_+_99601498 4.701 NM_016337
EVL
Enah/Vasp-like
chr14_+_99601517 4.686 EVL
Enah/Vasp-like
chr6_-_159386007 4.626 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr16_-_3567354 4.621 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr6_+_31662454 4.617 NM_205837
LST1
leukocyte specific transcript 1
chr17_+_31455332 4.608 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr16_+_28413421 4.584 NM_018690
APOBR
apolipoprotein B receptor
chr2_-_225519974 4.575 DOCK10
dedicator of cytokinesis 10
chr5_-_169657192 4.557 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr17_+_37693090 4.491 NM_003152
STAT5A
signal transducer and activator of transcription 5A
chr5_-_71838875 4.459 NM_152625
ZNF366
zinc finger protein 366
chr12_+_48443232 4.411 TMBIM6
transmembrane BAX inhibitor motif containing 6
chr6_+_31661934 4.392 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr7_+_149779011 4.157 GIMAP8
GTPase, IMAP family member 8
chr5_-_169657312 4.156 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr3_-_113701073 4.135 NM_001085357
NM_181780
BTLA

B and T lymphocyte associated

chr5_-_169657395 4.027 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr7_+_106292932 4.014 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr17_+_31664143 3.966 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr7_+_106292975 3.963 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr11_-_60880799 3.962 NM_001161452
CYBASC3
cytochrome b, ascorbate dependent 3
chr21_-_38792173 3.877 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr17_+_73638430 3.877 NM_152468
TMC8
transmembrane channel-like 8
chr4_+_39874921 3.876 NM_004310
RHOH
ras homolog gene family, member H
chr5_-_169657360 3.784 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr14_+_87541220 3.674 NM_003608
GPR65
G protein-coupled receptor 65
chr5_-_176869148 3.667


chr13_+_110653407 3.659 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chrX_-_100527799 3.647 NM_000061
BTK
Bruton agammaglobulinemia tyrosine kinase
chr12_+_45896511 3.584 FAM113B
family with sequence similarity 113, member B
chr3_-_122862391 3.550 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_+_207995999 3.536 NM_025228
TRAF3IP3
TRAF3 interacting protein 3
chr3_-_122862447 3.514 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr17_-_24491521 3.486 MYO18A
myosin XVIIIA
chr17_+_44642587 3.461 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr9_-_129580732 3.461 NM_170600
SH2D3C
SH2 domain containing 3C
chr2_+_102401580 3.451 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr7_+_128367961 3.439 NM_001098627
IRF5
interferon regulatory factor 5
chr13_-_32678142 3.415 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr2_+_233633348 3.395 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr6_-_32268615 3.380 GPSM3
G-protein signaling modulator 3
chr7_+_139175420 3.355 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr1_-_111848265 3.345 NM_000677
NM_020683
ADORA3

adenosine A3 receptor

chr5_-_176869463 3.334 NM_024872
DOK3
docking protein 3
chr19_-_6432765 3.320 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr5_-_176869440 3.289 DOK3
docking protein 3
chr1_-_205161821 3.280 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr2_+_233633279 3.249 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr7_+_149895390 3.245 NM_018326
GIMAP4
GTPase, IMAP family member 4
chr9_+_263025 3.241 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr1_-_154727014 3.203 MEF2D
myocyte enhancer factor 2D
chr15_+_79376295 3.191 NM_004513
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr16_-_30301357 3.113 SEPT1
septin 1
chr11_-_66961709 3.070 NM_005608
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr6_-_25044156 3.038 FAM65B
family with sequence similarity 65, member B
chr12_+_48443588 3.025 TMBIM6
transmembrane BAX inhibitor motif containing 6
chr1_+_111818111 3.014 NM_174896
C1orf162
chromosome 1 open reading frame 162
chr1_+_149877955 2.946 SNX27
sorting nexin family member 27
chr12_-_56157898 2.929 NM_001080156
ARHGAP9
Rho GTPase activating protein 9
chr16_+_31105579 2.889


chr3_+_46423682 2.883 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr19_+_54530458 2.881 CD37
CD37 molecule
chr7_-_38341697 2.865 TRGV7
T cell receptor gamma variable 7 pseudogene
chr3_-_120761092 2.840 NM_005191
CD80
CD80 molecule
chr19_+_54530497 2.839 CD37
CD37 molecule
chr7_-_4867963 2.839 NM_020144
PAPOLB
poly(A) polymerase beta (testis specific)
chr19_+_54530485 2.830 NM_001040031
NM_001774
CD37

CD37 molecule

chr11_+_65164167 2.820 NM_153253
SIPA1
signal-induced proliferation-associated 1
chr19_+_46774370 2.788 NM_001098506
NM_033543
CEACAM21

carcinoembryonic antigen-related cell adhesion molecule 21

chr1_+_157441133 2.761 NM_002036
DARC
Duffy blood group, chemokine receptor
chr12_+_25096472 2.760 NM_006152
LRMP
lymphoid-restricted membrane protein
chr19_+_54530512 2.750 CD37
CD37 molecule
chr11_+_120966280 2.720 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr19_+_54530546 2.649 CD37
CD37 molecule
chr11_-_58736897 2.627 NM_001039396
MPEG1
macrophage expressed 1
chr1_+_242281199 2.623 ZNF238
zinc finger protein 238
chr12_-_56159631 2.616 NM_001080157
ARHGAP9
Rho GTPase activating protein 9
chr2_-_224974954 2.566 NM_001122779
NM_024785
FAM124B

family with sequence similarity 124B

chrX_-_44945025 2.549 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr5_+_143171918 2.549 NM_021182
HMHB1
histocompatibility (minor) HB-1
chr1_-_158759606 2.548 NM_001184714
NM_001184715
NM_001184716
NM_052931
SLAMF6



SLAM family member 6



chr12_+_53177806 2.547 NCKAP1L
NCK-associated protein 1-like
chr12_+_45896318 2.529 NM_138371
FAM113B
family with sequence similarity 113, member B
chr12_+_53177789 2.500 NCKAP1L
NCK-associated protein 1-like
chr12_-_10142779 2.495 NM_016511
CLEC1A
C-type lectin domain family 1, member A
chr1_-_25164061 2.494 NM_001031680
RUNX3
runt-related transcription factor 3
chr17_+_7180571 2.493 NM_014716
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr4_-_10295412 2.491 NM_052964
CLNK
cytokine-dependent hematopoietic cell linker
chr19_+_14412052 2.468 PKN1
protein kinase N1
chr19_+_14412080 2.447 NM_213560
PKN1
protein kinase N1
chr5_+_168996852 2.445 DOCK2
dedicator of cytokinesis 2
chr5_-_156468614 2.430 NM_032782
HAVCR2
hepatitis A virus cellular receptor 2
chr1_+_242281175 2.418 NM_205768
ZNF238
zinc finger protein 238
chr19_+_14554895 2.406 NM_207390
CLEC17A
C-type lectin domain family 17, member A
chr17_+_31562577 2.406 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr2_+_96355661 2.397 NM_178495
NM_001163524
ITPRIPL1

inositol 1,4,5-triphosphate receptor interacting protein-like 1

chr6_+_31647854 2.384 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr19_+_14412087 2.383 PKN1
protein kinase N1
chr1_+_202000906 2.377 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr19_-_56567602 2.375 NM_005601
NKG7
natural killer cell group 7 sequence
chr8_+_11388918 2.370 NM_001715
BLK
B lymphoid tyrosine kinase
chrX_-_70248022 2.367 NM_000206
IL2RG
interleukin 2 receptor, gamma
chr9_+_92629525 2.363 NM_001174167
SYK
spleen tyrosine kinase
chr11_-_33847507 2.355 LMO2
LIM domain only 2 (rhombotin-like 1)
chr18_+_41659542 2.338 NM_213602
SIGLEC15
sialic acid binding Ig-like lectin 15
chr12_+_53177758 2.311 NM_005337
NCKAP1L
NCK-associated protein 1-like
chr1_-_47468029 2.310 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chrX_-_134257624 2.308 NM_001185063
NM_007131
ZNF75D

zinc finger protein 75D

chr17_+_2646481 2.300 NM_001100398
NM_015085
RAP1GAP2

RAP1 GTPase activating protein 2

chr6_+_31690957 2.290 NM_004847
NM_001623
AIF1

allograft inflammatory factor 1

chr11_+_59979857 2.287 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr16_-_30301634 2.277 NM_052838
SEPT1
septin 1
chr16_-_88358946 2.227 FANCA
Fanconi anemia, complementation group A
chr4_-_101658094 2.209 NM_001159694
NM_016242
EMCN

endomucin

chr1_-_181826086 2.182 NCF2
neutrophil cytosolic factor 2
chr5_+_140772691 2.175 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr9_+_27099138 2.167 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr5_-_138822475 2.160 NM_001077693
ECSCR
endothelial cell-specific chemotaxis regulator
chr12_+_53178834 2.150 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chr2_-_68952006 2.136 NM_014482
BMP10
bone morphogenetic protein 10
chr9_+_126094067 2.134 NM_001166170
NM_001166171
NEK6

NIMA (never in mitosis gene a)-related kinase 6

chr4_-_164754106 2.126 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr19_+_10083196 2.125 NM_002566
P2RY11
purinergic receptor P2Y, G-protein coupled, 11
chr16_+_29581783 2.122 NM_001030288
SPN
sialophorin
chrX_-_47374187 2.113 NM_001145252
CFP
complement factor properdin
chr5_-_156468571 2.102 HAVCR2
hepatitis A virus cellular receptor 2
chr16_-_49272741 2.102 NM_001144972
NM_153337
NM_182854
SNX20


sorting nexin 20


chr7_-_37454933 2.099 NM_014800
ELMO1
engulfment and cell motility 1
chr19_-_13074973 2.067 NM_005583
LYL1
lymphoblastic leukemia derived sequence 1
chr1_-_171441234 2.065 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr6_+_158654464 2.060 TULP4
tubby like protein 4
chr1_-_171442937 2.057 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr16_-_49272617 2.055 SNX20
sorting nexin 20
chr6_+_158654890 2.047


chr1_-_205210567 2.045 NM_001122979
NM_001170631
NM_032029
FCAMR


Fc receptor, IgA, IgM, high affinity


chr12_+_50592379 2.045 NM_001077401
ACVRL1
activin A receptor type II-like 1
chr1_+_154390939 2.028 SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr1_-_181826633 2.023 NM_001127651
NCF2
neutrophil cytosolic factor 2
chr1_+_100957883 2.022 NM_001078
NM_080682
VCAM1

vascular cell adhesion molecule 1

chr7_+_73145481 2.007 LIMK1
LIM domain kinase 1
chr12_+_102505180 1.992 NM_017564
STAB2
stabilin 2
chr1_-_21478571 1.984 NM_001113347
ECE1
endothelin converting enzyme 1
chr19_-_53935648 1.983 NM_017805
RASIP1
Ras interacting protein 1
chr6_-_56824672 1.980 DST
dystonin
chr22_+_35586950 1.978 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr12_+_53241365 1.969 NM_001165975
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr3_+_120799411 1.965 NM_015900
PLA1A
phospholipase A1 member A
chr12_+_6930815 1.959 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr14_+_23852152 1.956 NM_181657
LTB4R
leukotriene B4 receptor
chr17_-_44058612 1.941 NM_024017
HOXB9
homeobox B9
chr1_-_181826292 1.931 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr3_-_184756101 1.928 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr9_+_107464558 1.924 NM_005421
TAL2
T-cell acute lymphocytic leukemia 2
chr16_+_29582065 1.920 SPN
sialophorin
chr9_+_138677197 1.919 NM_201446
NM_016215
EGFL7

EGF-like-domain, multiple 7

chr22_+_35639564 1.911 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr22_+_21359175 1.886 IGLV3-25
immunoglobulin lambda variable 3-25
chr12_+_6930778 1.863 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr15_+_38849450 1.860 NM_001130448
C15orf62
chromosome 15 open reading frame 62
chr18_-_51219880 1.857 TCF4
transcription factor 4
chr12_+_6930799 1.857 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chrX_+_15428820 1.856 NM_203281
BMX
BMX non-receptor tyrosine kinase
chr12_+_6930804 1.854 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr12_+_6751930 1.851 NM_002286
LAG3
lymphocyte-activation gene 3
chr6_+_167456230 1.849 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr17_+_18971506 1.848 NM_001129778
GRAPL
GRB2-related adaptor protein-like
chr9_+_124835608 1.845 RABGAP1
GPR21
RAB GTPase activating protein 1
G protein-coupled receptor 21
chr12_+_9713472 1.836 NM_001197318
NM_013269
NM_001004419
NM_001197317
NM_001197319
CLEC2D




C-type lectin domain family 2, member D




chr12_+_6930694 1.833 NM_002831
NM_080549
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr7_-_81237162 1.830 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr12_+_6930792 1.827 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr4_+_68107039 1.825 NM_012108
STAP1
signal transducing adaptor family member 1
chr16_+_29582069 1.815 NM_003123
SPN
sialophorin
chr1_+_148511806 1.811 NM_024579
C1orf54
chromosome 1 open reading frame 54
chr12_+_6930734 1.805 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr1_-_240228987 1.803 NM_001004343
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr1_+_149395728 1.803 NM_024575
TNFAIP8L2
tumor necrosis factor, alpha-induced protein 8-like 2
chr1_+_50348052 1.779 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr12_+_8499788 1.769 NM_001007033
CLEC6A
C-type lectin domain family 6, member A
chr6_-_56824371 1.763 DST
dystonin
chr6_-_154719560 1.749 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.46 1.10e-14 GO:0002376 immune system process
1.13 9.30e-10 GO:0050794 regulation of cellular process
1.12 2.88e-09 GO:0050789 regulation of biological process
1.11 1.07e-08 GO:0065007 biological regulation
1.54 4.22e-07 GO:0007599 hemostasis
1.55 4.43e-07 GO:0007596 blood coagulation
1.55 4.43e-07 GO:0050817 coagulation
1.19 5.92e-07 GO:0007165 signal transduction
1.27 9.31e-07 GO:0016070 RNA metabolic process
1.25 5.05e-06 GO:0010467 gene expression
1.47 7.06e-06 GO:0050878 regulation of body fluid levels
1.37 7.06e-06 GO:0009611 response to wounding
1.12 7.85e-06 GO:0050896 response to stimulus
1.50 9.69e-06 GO:0001775 cell activation
1.15 1.56e-05 GO:0051716 cellular response to stimulus
1.16 1.67e-05 GO:0023052 signaling
1.39 2.00e-05 GO:0006955 immune response
1.39 7.52e-05 GO:0002682 regulation of immune system process
1.85 9.17e-05 GO:0050900 leukocyte migration
1.43 9.63e-05 GO:0042060 wound healing
1.20 2.29e-04 GO:0090304 nucleic acid metabolic process
1.48 2.54e-04 GO:0002684 positive regulation of immune system process
1.18 3.14e-04 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22 4.10e-04 GO:0007166 cell surface receptor linked signaling pathway
1.13 4.56e-04 GO:0044260 cellular macromolecule metabolic process
1.05 5.22e-04 GO:0009987 cellular process
1.84 5.36e-04 GO:0050870 positive regulation of T cell activation
1.72 6.07e-04 GO:0050867 positive regulation of cell activation
1.75 6.19e-04 GO:0051251 positive regulation of lymphocyte activation
1.73 1.10e-03 GO:0050863 regulation of T cell activation
1.18 1.39e-03 GO:0048519 negative regulation of biological process
1.70 1.40e-03 GO:0002696 positive regulation of leukocyte activation
1.18 1.59e-03 GO:0006950 response to stress
1.44 1.86e-03 GO:0050776 regulation of immune response
1.20 2.08e-03 GO:0048583 regulation of response to stimulus
1.19 2.33e-03 GO:0048523 negative regulation of cellular process
1.17 3.01e-03 GO:0048522 positive regulation of cellular process
1.62 3.12e-03 GO:0051249 regulation of lymphocyte activation
1.14 4.15e-03 GO:0031323 regulation of cellular metabolic process
1.27 4.57e-03 GO:0042981 regulation of apoptosis
1.58 4.95e-03 GO:0002694 regulation of leukocyte activation
1.28 6.26e-03 GO:0032774 RNA biosynthetic process
1.27 7.13e-03 GO:0043067 regulation of programmed cell death
1.57 7.63e-03 GO:0045321 leukocyte activation
1.55 8.63e-03 GO:0050865 regulation of cell activation
1.37 8.65e-03 GO:0006928 cellular component movement
1.16 8.84e-03 GO:0048518 positive regulation of biological process
1.34 9.40e-03 GO:0006396 RNA processing
1.26 1.07e-02 GO:0010941 regulation of cell death
1.62 1.35e-02 GO:0046649 lymphocyte activation
1.56 1.71e-02 GO:0030168 platelet activation
1.87 2.26e-02 GO:0050851 antigen receptor-mediated signaling pathway
1.29 2.66e-02 GO:0006952 defense response
1.10 2.89e-02 GO:0043170 macromolecule metabolic process
1.35 3.61e-02 GO:0016071 mRNA metabolic process
1.41 3.90e-02 GO:0006397 mRNA processing

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 7.08e-07 GO:0005829 cytosol
1.11 7.50e-05 GO:0005634 nucleus
1.03 1.10e-04 GO:0005623 cell
1.03 1.36e-04 GO:0044464 cell part
1.19 1.73e-04 GO:0044428 nuclear part
1.20 7.64e-04 GO:0031981 nuclear lumen
1.05 1.63e-03 GO:0044424 intracellular part
1.37 1.81e-03 GO:0030529 ribonucleoprotein complex
1.04 4.63e-03 GO:0005622 intracellular
1.12 5.60e-03 GO:0032991 macromolecular complex
2.92 2.00e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
1.14 4.14e-02 GO:0031974 membrane-enclosed lumen
1.19 4.95e-02 GO:0005654 nucleoplasm

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.12 5.28e-11 GO:0005515 protein binding
1.37 3.28e-06 GO:0003723 RNA binding
1.13 5.65e-03 GO:0003676 nucleic acid binding
1.29 8.48e-03 GO:0019899 enzyme binding
1.04 9.49e-03 GO:0005488 binding
1.23 4.02e-02 GO:0001071 nucleic acid binding transcription factor activity
1.23 4.02e-02 GO:0003700 sequence-specific DNA binding transcription factor activity