• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: STAT2,4,6.p2

Z-value: 1.504

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr14_+_94148466	1.963	NM_001085	SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr19_-_49552638	1.673	NM_001083335 NM_013380	ZFP112	zinc finger protein 112 homolog (mouse)
chr12_+_51730101	1.666	NM_170754	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr3_-_71376919	1.647		FOXP1	forkhead box P1
chr8_-_27525084	1.465	NM_001171138	CLU	clusterin
chr11_+_57121602	1.425	NM_000062	SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr2_-_178645718	1.375	NM_016953	PDE11A	phosphodiesterase 11A
chr3_-_52839727	1.373	NM_001166449 NM_002218	ITIH4	inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)
chr2_-_218516950	1.367	NM_022648	TNS1	tensin 1
chr14_-_93988838	1.349	NM_001080451	SERPINA11	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
chr11_+_57122153	1.289	NM_001032295	SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr5_+_145296313	1.272	NM_152550	SH3RF2	SH3 domain containing ring finger 2
chr8_-_27524744	1.211	NM_203339	CLU	clusterin
chr2_-_43919392	1.173	NM_022436	ABCG5	ATP-binding cassette, sub-family G (WHITE), member 5
chr9_+_676640	1.146
chr14_+_23855291	1.136		LTB4R	leukotriene B4 receptor
chr1_+_17779528	1.134	NM_001011722	ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like
chr19_+_15079141	1.078	NM_033025	SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr12_+_51729239	1.072		TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr22_+_29848923	1.063	NM_001002837	INPP5J	inositol polyphosphate-5-phosphatase J
chr3_+_173043832	1.060	NM_001164436	TMEM212	transmembrane protein 212
chr3_+_189353502	1.050		LPP	LIM domain containing preferred translocation partner in lipoma
chr17_+_1593040	1.018	NM_001165920	SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr3_-_156876798	1.010	NM_001130960 NM_001130961	PLCH1	phospholipase C, eta 1
chr15_-_88256922	0.995	NM_001199058 NM_182616	C15orf38-AP3S2 C15orf38	C15orf38-AP3S2 readthrough chromosome 15 open reading frame 38
chr2_+_43919606	0.992	NM_022437	ABCG8	ATP-binding cassette, sub-family G (WHITE), member 8
chr3_+_52803823	0.970	NM_002217	ITIH3	inter-alpha (globulin) inhibitor H3
chr3_+_187813553	0.945		AHSG	alpha-2-HS-glycoprotein
chr4_-_155731288	0.945	NM_000508 NM_021871	FGA	fibrinogen alpha chain
chr2_+_108360798	0.885	NM_006588	SULT1C4	sulfotransferase family, cytosolic, 1C, member 4
chr5_+_140454382	0.884	NM_018936	PCDHB2	protocadherin beta 2
chr1_-_20682541	0.861
chr16_-_28457728	0.859		NUPR1	nuclear protein, transcriptional regulator, 1
chr12_+_54700955	0.847	NM_022465	IKZF4	IKAROS family zinc finger 4 (Eos)
chr16_+_29378694	0.847	NM_001017390 NM_177552	SULT1A4 SULT1A3	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr3_+_187813405	0.846		AHSG	alpha-2-HS-glycoprotein
chr11_-_116168316	0.841	NM_001166598 NM_052968	APOA5	apolipoprotein A-V
chr3_+_187813538	0.838	NM_001622	AHSG	alpha-2-HS-glycoprotein
chr17_+_4621924	0.824	NM_003963	TM4SF5	transmembrane 4 L six family member 5
chr5_+_38882017	0.823		OSMR	oncostatin M receptor
chr6_-_152744143	0.818		SYNE1	spectrin repeat containing, nuclear envelope 1
chr16_+_70646008	0.816	NM_001126102 NM_005143	HP	haptoglobin
chr12_+_7038240	0.809	NM_001734 NM_201442	C1S	complement component 1, s subcomponent
chr16_-_55259405	0.805	NM_005950	MT1G	metallothionein 1G
chr17_+_1592893	0.801		SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr17_+_1592879	0.790	NM_000934 NM_001165921	SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr16_+_30903963	0.789	NM_001142777 NM_001142778 NM_025193	HSD3B7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr14_-_93829347	0.788	NM_001100607	SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr16_-_28457825	0.781	NM_001042483 NM_012385	NUPR1	nuclear protein, transcriptional regulator, 1
chr1_+_200246312	0.778	NM_001114309 NM_004433	ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr3_-_185578621	0.772	NM_000460 NM_001177597 NM_001177598	THPO	thrombopoietin
chr6_+_30238961	0.768	NM_033229	TRIM15	tripartite motif containing 15
chr9_+_102830851	0.768	NM_207299	LPPR1	lipid phosphate phosphatase-related protein type 1
chr8_+_103889733	0.762		FLJ45248	FLJ45248 protein
chr14_+_23175383	0.759	NM_005794 NM_182908	DHRS2	dehydrogenase/reductase (SDR family) member 2
chr3_+_42176662	0.729	NM_014965	TRAK1	trafficking protein, kinesin binding 1
chr5_+_73145098	0.723		RGNEF	190 kDa guanine nucleotide exchange factor
chr1_-_11029882	0.722		MASP2	mannan-binding lectin serine peptidase 2
chr5_+_176449156	0.721	NM_022963	FGFR4	fibroblast growth factor receptor 4
chr16_+_2025922	0.719		SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr14_-_22516271	0.717	NM_198086	JUB	jub, ajuba homolog (Xenopus laevis)
chr14_-_24588916	0.705	NM_014178	STXBP6	syntaxin binding protein 6 (amisyn)
chr1_+_203740391	0.703		CDK18	cyclin-dependent kinase 18
chr16_-_65510230	0.702	NM_004062	CDH16	cadherin 16, KSP-cadherin
chr15_-_40236061	0.692	NM_213600	PLA2G4F	phospholipase A2, group IVF
chr11_-_8788765	0.690	NM_213618	ST5	suppression of tumorigenicity 5
chr11_-_66431910	0.672	NM_022172	PC	pyruvate carboxylase
chr20_-_14266200	0.668	NM_013281 NM_198391	FLRT3	fibronectin leucine rich transmembrane protein 3
chr1_-_11029737	0.667	NM_006610 NM_139208	MASP2	mannan-binding lectin serine peptidase 2
chr12_+_50633430	0.665	NM_020327	ACVR1B	activin A receptor, type IB
chr2_-_75650355	0.662	NM_032181	FAM176A	family with sequence similarity 176, member A
chr6_+_32003380	0.659		C2	complement component 2
chr14_+_37748031	0.650		SSTR1	somatostatin receptor 1
chr3_+_186529376	0.649		MAP3K13	mitogen-activated protein kinase kinase kinase 13
chr16_+_88515917	0.647	NM_001197181	TUBB3	tubulin, beta 3
chr14_-_64479198	0.644	NM_002083	GPX2	glutathione peroxidase 2 (gastrointestinal)
chr9_-_114814286	0.635	NM_001101338	ZNF883	zinc finger protein 883
chr1_-_159474503	0.624	NM_001077469 NM_001077470 NM_001077471 NM_001077472 NM_001077473 NM_001077474 NM_001077475 NM_001077476 NM_001077477 NM_001077478 NM_001077479 NM_001077480 NM_001077481 NM_001077482 NM_005122	NR1I3	nuclear receptor subfamily 1, group I, member 3
chr12_-_55730125	0.624	NM_005379	MYO1A	myosin IA
chr5_+_57914658	0.621	NM_138453	RAB3C	RAB3C, member RAS oncogene family
chr6_-_152744022	0.621		SYNE1	spectrin repeat containing, nuclear envelope 1
chr11_+_62893836	0.619	NM_080866	SLC22A9	solute carrier family 22 (organic anion transporter), member 9
chr6_+_32021899	0.619		CFB	complement factor B
chr3_-_150422474	0.619	NM_000096	CP	ceruloplasmin (ferroxidase)
chr2_+_17585287	0.614	NM_003385	VSNL1	visinin-like 1
chr2_-_228290942	0.612	NM_025243	SLC19A3	solute carrier family 19, member 3
chr6_+_32021831	0.605		CFB	complement factor B
chr16_-_20246309	0.603	NM_001007240 NM_001007241 NM_001007242 NM_001502	GP2	glycoprotein 2 (zymogen granule membrane)
chr17_+_35425139	0.598	NM_000759 NM_001178147 NM_172219 NM_172220	CSF3	colony stimulating factor 3 (granulocyte)
chr6_+_32021793	0.596		CFB	complement factor B
chr1_-_228916486	0.596		AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr1_-_228916470	0.593		AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr6_+_32021742	0.593		CFB	complement factor B
chr2_+_27573206	0.592	NM_001486	GCKR	glucokinase (hexokinase 4) regulator
chr6_-_31953425	0.591	NM_001178045	SLC44A4	solute carrier family 44, member 4
chr14_+_37748345	0.580		SSTR1	somatostatin receptor 1
chr2_-_166940710	0.579	NM_002977	SCN9A	sodium channel, voltage-gated, type IX, alpha subunit
chr7_-_149669622	0.577	NM_002889	RARRES2	retinoic acid receptor responder (tazarotene induced) 2
chr19_+_40465249	0.576	NM_021175	HAMP	hepcidin antimicrobial peptide
chr15_-_40173949	0.575	NM_178034	PLA2G4D	phospholipase A2, group IVD (cytosolic)
chr2_+_201158824	0.567		AOX1	aldehyde oxidase 1
chr5_-_121842680	0.564
chr1_-_228916958	0.564	NM_000029	AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr20_-_48741481	0.551
chr11_+_7463175	0.549	NM_198474	OLFML1	olfactomedin-like 1
chr1_+_200246370	0.549		ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr5_-_38881636	0.540
chr4_-_100284395	0.534	NM_000670	ADH4	alcohol dehydrogenase 4 (class II), pi polypeptide
chr19_+_702108	0.534	NM_173481	C19orf21	chromosome 19 open reading frame 21
chr6_+_32021687	0.531	NM_001710	CFB	complement factor B
chr12_-_9159789	0.525	NM_000014	A2M	alpha-2-macroglobulin
chr22_+_19458378	0.522	NM_000185	SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr20_-_52223918	0.522	NM_000782 NM_001128915	CYP24A1	cytochrome P450, family 24, subfamily A, polypeptide 1
chr12_-_51200347	0.519	NM_000424	KRT5	keratin 5
chr15_+_60838053	0.515		TLN2	talin 2
chr12_-_53059234	0.508		ZNF385A	zinc finger protein 385A
chr20_-_44713466	0.507	NM_001193339 NM_001193342 NM_022829	SLC13A3	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
chr14_-_93829113	0.499	NM_016186	SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr1_+_154178103	0.496	NM_181885	RXFP4	relaxin/insulin-like family peptide receptor 4
chr1_-_228916559	0.496		AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr20_-_47963682	0.495	NM_001135773	SPATA2	spermatogenesis associated 2
chr2_+_27225362	0.494	NM_175769	TCF23	transcription factor 23
chr3_-_56477404	0.494	NM_015576	ERC2	ELKS/RAB6-interacting/CAST family member 2
chr10_+_17891348	0.488	NM_001009567 NM_002438	MRC1L1 MRC1	mannose receptor, C type 1-like 1 mannose receptor, C type 1
chr1_+_32485404	0.488	NM_032648	FAM167B	family with sequence similarity 167, member B
chr19_-_12028126	0.487	NM_001080404	ZNF878	zinc finger protein 878
chr10_+_123744131	0.484		TACC2	transforming, acidic coiled-coil containing protein 2
chr2_-_208702760	0.484	NM_020989	CRYGC	crystallin, gamma C
chr1_+_95058488	0.478	NM_001114106	SLC44A3	solute carrier family 44, member 3
chrX_+_115481774	0.476	NM_007231	SLC6A14	solute carrier family 6 (amino acid transporter), member 14
chr4_+_3413457	0.476		HGFAC	HGF activator
chr16_+_56286212	0.474	NM_032269	CCDC135	coiled-coil domain containing 135
chr19_-_63556632	0.473	NM_130786	A1BG	alpha-1-B glycoprotein
chr5_+_148631588	0.471	NM_001146337 NM_152406	AFAP1L1	actin filament associated protein 1-like 1
chr5_+_131437383	0.469	NM_000758	CSF2	colony stimulating factor 2 (granulocyte-macrophage)
chr9_-_116305273	0.466	NM_001083885	DFNB31	deafness, autosomal recessive 31
chr5_+_148631636	0.466		AFAP1L1	actin filament associated protein 1-like 1
chr17_-_7023283	0.464		ASGR1	asialoglycoprotein receptor 1
chr16_+_79829794	0.462	NM_017429	BCMO1	beta-carotene 15,15'-monooxygenase 1
chr1_-_7895873	0.460		UTS2	urotensin 2
chr3_+_189354167	0.459	NM_001167672	LPP	LIM domain containing preferred translocation partner in lipoma
chrX_-_132947290	0.458	NM_001164617 NM_001164618 NM_001164619 NM_004484	GPC3	glypican 3
chr19_-_54258935	0.456	NM_006179	NTF4	neurotrophin 4
chr2_+_69974581	0.456	NM_006857	SNRNP27	small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr16_+_68765428	0.455	NM_173619	CLEC18C CLEC18A CLEC18B	C-type lectin domain family 18, member C C-type lectin domain family 18, member A C-type lectin domain family 18, member B
chr17_-_74487527	0.455	NM_005567	LGALS3BP	lectin, galactoside-binding, soluble, 3 binding protein
chr7_+_134114912	0.454		CALD1	caldesmon 1
chr5_+_38881719	0.453	NM_003999	OSMR	oncostatin M receptor
chr10_-_116434364	0.452	NM_001003407 NM_001003408	ABLIM1	actin binding LIM protein 1
chr14_-_22468393	0.452		PRMT5	protein arginine methyltransferase 5
chr8_-_130868315	0.450	NM_031415	GSDMC	gasdermin C
chr17_-_202617	0.450	NM_001190411 NM_001190412 NM_001190413 NM_006987	RPH3AL	rabphilin 3A-like (without C2 domains)
chr12_-_6356783	0.449	NM_001159575	SCNN1A	sodium channel, nonvoltage-gated 1 alpha
chr20_+_35406497	0.448	NM_005417	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chrX_+_109548940	0.447	NM_020769	RGAG1	retrotransposon gag domain containing 1
chr6_-_56615544	0.447	NM_001723 NM_015548	DST	dystonin
chr7_+_134114957	0.446		CALD1	caldesmon 1
chr14_-_22974707	0.443	NM_000257	MYH7	myosin, heavy chain 7, cardiac muscle, beta
chr4_-_155753207	0.441		FGG	fibrinogen gamma chain
chr11_-_11986704	0.438	NM_001018057	DKK3	dickkopf homolog 3 (Xenopus laevis)
chr19_-_5790702	0.438	NM_000150 NM_001040701	FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
chr1_-_199635240	0.438	NM_005558	LAD1	ladinin 1
chr2_+_201158975	0.437	NM_001159	AOX1	aldehyde oxidase 1
chr15_-_38908197	0.436	NM_001130143 NM_017726	PPP1R14D	protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr10_-_116434102	0.435		ABLIM1	actin binding LIM protein 1
chr4_-_155753249	0.431		FGG	fibrinogen gamma chain
chr16_-_73012740	0.430	NM_001011880	CLEC18C CLEC18A CLEC18B	C-type lectin domain family 18, member C C-type lectin domain family 18, member A C-type lectin domain family 18, member B
chr22_-_29866339	0.427	NM_015715	PLA2G3	phospholipase A2, group III
chr4_+_3413489	0.426	NM_001528	HGFAC	HGF activator
chr6_+_25760352	0.426	NM_006998	SCGN	secretagogin, EF-hand calcium binding protein
chr10_+_75343352	0.426		PLAU	plasminogen activator, urokinase
chr1_+_95058687	0.423	NM_152369	SLC44A3	solute carrier family 44, member 3
chr12_+_51728999	0.423	NM_015319	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr9_-_34618010	0.422	NM_001017363	ARID3C	AT rich interactive domain 3C (BRIGHT-like)
chr11_-_2881750	0.421	NM_007105	SLC22A18AS	solute carrier family 22 (organic cation transporter), member 18 antisense
chr16_+_56211410	0.421	NM_001145770 NM_005682	GPR56	G protein-coupled receptor 56
chr6_-_42218692	0.421	NM_001164446	C6orf132	chromosome 6 open reading frame 132
chr12_+_6363482	0.419	NM_002342	LTBR	lymphotoxin beta receptor (TNFR superfamily, member 3)
chr4_-_155753272	0.416		FGG	fibrinogen gamma chain
chr8_-_127639892	0.414	NM_174911	FAM84B	family with sequence similarity 84, member B
chr2_-_200028977	0.414		SATB2	SATB homeobox 2
chr5_+_40945315	0.413	NM_000587	C7	complement component 7
chr19_+_40299058	0.410		FXYD3	FXYD domain containing ion transport regulator 3
chr3_-_158700036	0.408	NM_024621	VEPH1	ventricular zone expressed PH domain homolog 1 (zebrafish)
chr19_+_49248003	0.408	NM_013361	ZNF223	zinc finger protein 223
chr5_+_149717394	0.406	NM_000356 NM_001008657 NM_001135243 NM_001135244 NM_001135245 NM_001195141	TCOF1	Treacher Collins-Franceschetti syndrome 1
chr14_+_37746937	0.402	NM_001049	SSTR1	somatostatin receptor 1
chr6_+_36752244	0.401	NM_078467	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr4_-_155753332	0.401	NM_000509 NM_021870	FGG	fibrinogen gamma chain
chr20_+_42417752	0.400	NM_001030003 NM_001030004 NM_175914	HNF4A	hepatocyte nuclear factor 4, alpha
chr2_-_152538694	0.399	NM_001005747	CACNB4	calcium channel, voltage-dependent, beta 4 subunit
chr16_+_68542126	0.398	NM_001136214	CLEC18A	C-type lectin domain family 18, member A
chr19_-_56582997	0.397	NM_001161748 NM_030657	LIM2	lens intrinsic membrane protein 2, 19kDa
chr20_-_5982617	0.396	NM_152611	LRRN4	leucine rich repeat neuronal 4
chr17_-_7023378	0.395	NM_001197216 NM_001671	ASGR1	asialoglycoprotein receptor 1
chr4_-_155753287	0.395		FGG	fibrinogen gamma chain
chr19_-_5821546	0.395	NM_002034	FUT5	fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr17_-_23721430	0.393		VTN	vitronectin
chr17_+_29606408	0.393	NM_002982	CCL2	chemokine (C-C motif) ligand 2
chr10_+_71482362	0.393	NM_018649	H2AFY2	H2A histone family, member Y2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.01	2.56e-02	GO:0034330	cell junction organization
2.07	2.86e-02	GO:0034329	cell junction assembly

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.83	9.99e-04	GO:0016323	basolateral plasma membrane
2.29	1.53e-03	GO:0005925	focal adhesion
2.00	2.69e-03	GO:0005912	adherens junction
2.17	4.23e-03	GO:0030055	cell-substrate junction
2.18	4.91e-03	GO:0005924	cell-substrate adherens junction
1.85	1.75e-02	GO:0070161	anchoring junction
3.94	2.32e-02	GO:0030530	heterogeneous nuclear ribonucleoprotein complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.11	4.24e-04	GO:0005515	protein binding
1.05	3.89e-02	GO:0005488	binding
6.08	4.10e-02	GO:0003708	retinoic acid receptor activity