Motif ID: TFAP4.p2

Z-value: 1.407


Transcription factors associated with TFAP4.p2:

Gene SymbolEntrez IDGene Name
TFAP4 7023 transcription factor AP-4 (activating enhancer binding protein 4)



Activity profile for motif TFAP4.p2.

activity profile for motif TFAP4.p2


Sorted Z-values histogram for motif TFAP4.p2

Sorted Z-values for motif TFAP4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP4.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_21868380 2.309 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr12_+_52105131 2.234 AMHR2
anti-Mullerian hormone receptor, type II
chr12_-_56157898 1.974 NM_001080156
ARHGAP9
Rho GTPase activating protein 9
chr9_+_139292094 1.818 NM_017723
C9orf167
chromosome 9 open reading frame 167
chr12_+_56135353 1.793 NM_031479
INHBE
inhibin, beta E
chr1_-_6585268 1.588 KLHL21
kelch-like 21 (Drosophila)
chr19_-_54350457 1.517 NM_002152
HRC
histidine rich calcium binding protein
chr19_+_1236766 1.514 NM_001405
EFNA2
ephrin-A2
chr22_-_49311722 1.509 NM_001169109
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr22_-_20235372 1.487 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr22_+_20068039 1.477 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr2_+_128119908 1.471 NM_001161415
NM_001161416
NM_001161417
NM_005291
GPR17



G protein-coupled receptor 17



chr5_+_176726918 1.446 RGS14
regulator of G-protein signaling 14
chr14_+_102636233 1.438 NM_001077594
EXOC3L4
exocyst complex component 3-like 4
chr16_+_73810383 1.302 NM_001906
CTRB1
CTRB2
chymotrypsinogen B1
chymotrypsinogen B2
chr1_-_218168137 1.299 SLC30A10
solute carrier family 30, member 10
chr9_+_133154896 1.251 NM_032728
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr2_+_43919606 1.250 NM_022437
ABCG8
ATP-binding cassette, sub-family G (WHITE), member 8
chr22_+_19649417 1.240 NM_001018060
NM_144704
AIFM3

apoptosis-inducing factor, mitochondrion-associated, 3

chr20_+_61838479 1.178 LIME1
Lck interacting transmembrane adaptor 1
chr19_-_55156118 1.137 NM_001135163
NM_052884
SIGLEC11

sialic acid binding Ig-like lectin 11

chr2_+_47021816 1.108 NM_020458
TTC7A
tetratricopeptide repeat domain 7A
chr1_-_42978320 1.105 NM_001123395
NM_001185117
NM_148960
CLDN19


claudin 19


chr16_+_2461500 1.098 NM_006181
NTN3
netrin 3
chr14_-_22354457 1.089 SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr17_+_78286687 1.083 NM_022158
FN3K
fructosamine 3 kinase
chr22_+_21393107 1.080 IGLJ3
immunoglobulin lambda joining 3
chr20_+_2621193 1.080 NM_001110514
EBF4
early B-cell factor 4
chr17_+_25910709 1.075 NM_015594
TBC1D29
TBC1 domain family, member 29
chr3_-_13436802 1.065 NM_024923
NUP210
nucleoporin 210kDa
chr12_-_107257205 1.061 NM_001142343
NM_001142344
NM_004072
CMKLR1


chemokine-like receptor 1


chr8_-_145187553 1.060 NM_017570
OPLAH
5-oxoprolinase (ATP-hydrolysing)
chr22_-_49311439 1.051 NM_001169110
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr11_+_70915960 1.048 NM_001012503
KRTAP5-7
keratin associated protein 5-7
chr17_+_53769659 1.046 LOC100506779
hypothetical LOC100506779
chr1_+_54132447 1.043 NM_000792
NM_001039715
NM_001039716
NM_213593
DIO1



deiodinase, iodothyronine, type I



chr2_-_43919392 1.030 NM_022436
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr6_+_43565192 1.017 NM_001146017
TJAP1
tight junction associated protein 1 (peripheral)
chr21_-_44836811 1.010 NM_198688
KRTAP10-6
keratin associated protein 10-6
chr20_+_61838389 1.007 NM_017806
LIME1
Lck interacting transmembrane adaptor 1
chr14_-_22354389 1.007 SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr9_-_138958889 0.989 FBXW5
F-box and WD repeat domain containing 5
chr8_+_21968375 0.986 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr8_+_21968273 0.974 NM_001114136
NM_001114139
EPB49

erythrocyte membrane protein band 4.9 (dematin)

chr6_-_154873344 0.971 CNKSR3
CNKSR family member 3
chr16_+_620932 0.939 NM_053284
WFIKKN1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr1_-_925332 0.938 NM_001142467
NM_021170
HES4

hairy and enhancer of split 4 (Drosophila)

chr8_-_88955340 0.936 NM_152418
DCAF4L2
DDB1 and CUL4 associated factor 4-like 2
chr20_+_36867708 0.934 NM_001172735
NM_015568
PPP1R16B

protein phosphatase 1, regulatory (inhibitor) subunit 16B

chrX_-_153632990 0.922 GAB3
GRB2-associated binding protein 3
chr5_+_61637701 0.916 NM_001098511
NM_004520
KIF2A

kinesin heavy chain member 2A

chr19_+_11510578 0.898 NM_001299
CNN1
calponin 1, basic, smooth muscle
chr21_+_42697058 0.884 NM_001001895
NM_018961
UBASH3A

ubiquitin associated and SH3 domain containing A

chr21_+_44844924 0.884 NM_198689
KRTAP10-7
keratin associated protein 10-7
chr1_+_20385164 0.871 NM_152376
UBXN10
UBX domain protein 10
chr1_+_55277795 0.855 PCSK9
proprotein convertase subtilisin/kexin type 9
chr1_-_20014180 0.846 NM_019062
RNF186
ring finger protein 186
chr12_+_52103905 0.843 NM_001164690
NM_001164691
NM_020547
AMHR2


anti-Mullerian hormone receptor, type II


chr9_-_139042416 0.842 ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr8_-_38127489 0.842 NM_000349
STAR
steroidogenic acute regulatory protein
chr1_+_110012166 0.836 NM_000848
NM_001142368
GSTM2

glutathione S-transferase mu 2 (muscle)

chr2_-_20075889 0.834 MATN3
matrilin 3
chr16_+_68542310 0.830 NM_182619
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr4_-_977163 0.823 NM_022042
NM_134425
NM_213613
SLC26A1


solute carrier family 26 (sulfate transporter), member 1


chr19_-_56841819 0.823 NM_001098612
SIGLEC14
sialic acid binding Ig-like lectin 14
chr12_+_54361685 0.818 METTL7B
methyltransferase like 7B
chr6_+_31799099 0.818 NM_025260
NM_138272
NM_138273
NM_138274
NM_138275
NM_138277
C6orf25





chromosome 6 open reading frame 25





chr14_+_99859427 0.814 NM_207117
SLC25A47
solute carrier family 25, member 47
chr1_+_55277736 0.812 NM_174936
PCSK9
proprotein convertase subtilisin/kexin type 9
chr2_-_220144511 0.809 NM_001173408
NM_001173431
NM_015311
OBSL1


obscurin-like 1


chr2_-_20075929 0.805 NM_002381
MATN3
matrilin 3
chr13_+_112704077 0.804 MCF2L
MCF.2 cell line derived transforming sequence-like
chr3_-_57209319 0.803 NM_003865
HESX1
HESX homeobox 1
chr17_+_38259620 0.802 AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr1_-_218168404 0.786


chrX_-_55037235 0.785 NM_002625
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr20_+_62158882 0.778 NM_198723
TCEA2
transcription elongation factor A (SII), 2
chr2_-_74634569 0.778 NM_032603
LOXL3
lysyl oxidase-like 3
chr20_-_49592654 0.769 NM_012340
NM_173091
NFATC2

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

chr13_-_78075683 0.766 NM_006237
POU4F1
POU class 4 homeobox 1
chr2_+_10360471 0.764 NM_002149
HPCAL1
hippocalcin-like 1
chr13_+_112704028 0.764 MCF2L
MCF.2 cell line derived transforming sequence-like
chr16_-_21197138 0.763 CRYM
crystallin, mu
chr6_-_35804337 0.760 NM_001145775
FKBP5
FK506 binding protein 5
chr15_-_63502438 0.755 NM_020962
IGDCC4
immunoglobulin superfamily, DCC subclass, member 4
chr3_-_12175339 0.754 TIMP4
TIMP metallopeptidase inhibitor 4
chr16_-_87405817 0.748 NM_000485
NM_001030018
APRT

adenine phosphoribosyltransferase

chr4_+_3737872 0.745 ADRA2C
adrenergic, alpha-2C-, receptor
chr16_+_68765428 0.744 NM_173619
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr9_-_139183675 0.743


chr10_+_102722275 0.742 NM_017893
SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr19_-_60350122 0.741 TNNT1
troponin T type 1 (skeletal, slow)
chr8_+_104452877 0.737 CTHRC1
collagen triple helix repeat containing 1
chr6_-_38778807 0.736 GLO1
glyoxalase I
chr14_-_23810183 0.734 RABGGTA
Rab geranylgeranyltransferase, alpha subunit
chr17_-_53764867 0.733


chr16_+_51690564 0.731 CHD9
chromodomain helicase DNA binding protein 9
chr4_+_3413489 0.728 NM_001528
HGFAC
HGF activator
chr20_-_48203709 0.727 NM_001162505
NM_199129
NM_199203
TMEM189

TMEM189-UBE2V1
transmembrane protein 189

TMEM189-UBE2V1 readthrough
chr12_+_88626770 0.725 LOC338758
hypothetical LOC338758
chr13_+_112704051 0.721 MCF2L
MCF.2 cell line derived transforming sequence-like
chr6_+_32114060 0.718 NM_000500
NM_001128590
CYP21A2

cytochrome P450, family 21, subfamily A, polypeptide 2

chr20_+_31783426 0.718 NM_032819
ZNF341
zinc finger protein 341
chr20_-_62151216 0.717 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr6_-_38778860 0.717 GLO1
glyoxalase I
chr6_-_38778898 0.716 GLO1
glyoxalase I
chr7_+_44045202 0.716 FLJ35390
hypothetical LOC255031
chr1_-_51583281 0.716 NM_001144832
TTC39A
tetratricopeptide repeat domain 39A
chr22_-_37569679 0.716


chr6_-_38778893 0.715 GLO1
glyoxalase I
chr6_-_38778900 0.712 NM_006708
GLO1
glyoxalase I
chr7_-_156495985 0.711 NM_005515
MNX1
motor neuron and pancreas homeobox 1
chr12_+_119900931 0.703 NM_000545
HNF1A
HNF1 homeobox A
chr2_-_233060774 0.703 NM_004826
ECEL1
endothelin converting enzyme-like 1
chr19_+_46640902 0.702 NM_001130514
C19orf69
chromosome 19 open reading frame 69
chr1_+_16203317 0.702 NM_178840
C1orf64
chromosome 1 open reading frame 64
chr3_-_195553297 0.701 NM_001080513
CPN2
carboxypeptidase N, polypeptide 2
chr2_+_233029076 0.700 NM_001631
ALPI
alkaline phosphatase, intestinal
chr5_+_61637822 0.700 KIF2A
kinesin heavy chain member 2A
chr12_+_54361596 0.696 NM_152637
METTL7B
methyltransferase like 7B
chrX_+_152562013 0.695 DUSP9
dual specificity phosphatase 9
chr19_-_14030970 0.689 NM_001145028
PALM3
paralemmin 3
chr1_-_27113018 0.685 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr6_-_38778849 0.683 GLO1
glyoxalase I
chr7_+_88226617 0.680 NM_181646
ZNF804B
zinc finger protein 804B
chr19_+_40224480 0.678 HPN
hepsin
chr5_-_148738980 0.673 NM_014443
IL17B
interleukin 17B
chr3_+_127725851 0.670 NM_152889
CHST13
carbohydrate (chondroitin 4) sulfotransferase 13
chr6_+_32230172 0.668 PPT2
palmitoyl-protein thioesterase 2
chr12_-_91063441 0.668 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr17_-_202617 0.667 NM_001190411
NM_001190412
NM_001190413
NM_006987
RPH3AL



rabphilin 3A-like (without C2 domains)



chr8_-_142307854 0.666 NM_001080431
SLC45A4
solute carrier family 45, member 4
chr11_-_66945190 0.665 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr16_-_21197072 0.664 CRYM
crystallin, mu
chr7_+_100037817 0.663 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr10_+_134108643 0.663 NM_173541
C10orf91
chromosome 10 open reading frame 91
chr20_+_48241334 0.662 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr16_-_65918126 0.660 NM_001100915
KCTD19
potassium channel tetramerisation domain containing 19
chr17_-_36444626 0.657 NM_030966
KRTAP1-3
keratin associated protein 1-3
chr19_-_40696393 0.653 NM_001126056
NM_001126057
NM_001126058
NM_001190347
NM_001190348
NM_001190349
NM_033317
DMKN






dermokine






chr10_+_80498782 0.652 NM_020338
ZMIZ1
zinc finger, MIZ-type containing 1
chr20_-_3097070 0.651 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr2_-_220144427 0.651 OBSL1
obscurin-like 1
chr19_+_13090101 0.651 NM_052876
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr14_-_23810217 0.650 RABGGTA
Rab geranylgeranyltransferase, alpha subunit
chr17_-_202557 0.641 RPH3AL
rabphilin 3A-like (without C2 domains)
chr22_+_19649460 0.638 AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr19_-_55709577 0.638 NM_001024656
ASPDH
aspartate dehydrogenase domain containing
chr20_+_3399615 0.634 NM_139321
NM_139322
ATRN

attractin

chr7_+_156496360 0.634 LOC645249
hypothetical LOC645249
chr6_-_38778882 0.623 GLO1
glyoxalase I
chr7_-_156495314 0.620 MNX1
motor neuron and pancreas homeobox 1
chr19_-_6453224 0.619 NM_006087
TUBB4
tubulin, beta 4
chr2_+_11597530 0.618 NM_148903
GREB1
growth regulation by estrogen in breast cancer 1
chr1_-_32176475 0.615 PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr2_+_113601608 0.614 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr2_+_113601616 0.613 IL1RN
interleukin 1 receptor antagonist
chr1_-_37991160 0.609 EPHA10
EPH receptor A10
chr1_-_39871226 0.607 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr9_-_138958893 0.606 FBXW5
F-box and WD repeat domain containing 5
chr17_+_38256886 0.606


chr19_+_61379200 0.605 NM_001145546
NM_033106
GALP

galanin-like peptide

chr2_-_42573980 0.600 KCNG3
potassium voltage-gated channel, subfamily G, member 3
chr6_-_15771239 0.597 NM_032122
NM_183040
DTNBP1

dystrobrevin binding protein 1

chr16_+_28785087 0.596 SH2B1
SH2B adaptor protein 1
chr6_-_154873480 0.593 CNKSR3
CNKSR family member 3
chr12_-_192752 0.593 NM_003044
SLC6A12
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
chr3_-_50515857 0.592 NM_001005505
NM_001174051
NM_006030
CACNA2D2


calcium channel, voltage-dependent, alpha 2/delta subunit 2


chr17_-_36346240 0.591 KRT23
keratin 23 (histone deacetylase inducible)
chr20_-_61933012 0.590 ZBTB46
zinc finger and BTB domain containing 46
chr10_-_3817205 0.586 KLF6
Kruppel-like factor 6
chr1_-_32176562 0.586 NM_080391
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr7_-_127833231 0.586 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr11_+_67532592 0.586 NM_001161473
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr11_+_47958639 0.585 NM_001098503
NM_002843
PTPRJ

protein tyrosine phosphatase, receptor type, J

chr19_-_17420375 0.583 NM_001190844
TMEM221
transmembrane protein 221
chr1_+_1360765 0.582 NM_022834
NM_199121
VWA1

von Willebrand factor A domain containing 1

chr9_-_111123017 0.582 EPB41L4B
erythrocyte membrane protein band 4.1 like 4B
chr11_+_47958696 0.581 PTPRJ
protein tyrosine phosphatase, receptor type, J
chr20_-_61639104 0.578 NM_005975
PTK6
PTK6 protein tyrosine kinase 6
chr22_+_24468168 0.577 MYO18B
myosin XVIIIB
chr12_+_119900677 0.576 HNF1A
HNF1 homeobox A
chr16_-_55876099 0.576 PLLP
plasmolipin
chr11_+_384238 0.575 PKP3
plakophilin 3
chr16_+_23754997 0.571 PRKCB
protein kinase C, beta
chr3_-_10027770 0.568 NM_001008737
LOC401052
hypothetical LOC401052
chr9_+_115265827 0.566 NM_017790
RGS3
regulator of G-protein signaling 3
chr2_-_6923215 0.565 NM_207315
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr11_+_63730720 0.563 NM_031471
NM_178443
FERMT3

fermitin family member 3

chrX_+_48529905 0.561 NM_002049
GATA1
GATA binding protein 1 (globin transcription factor 1)
chr7_-_158073121 0.560 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr17_+_77453363 0.559 NM_148896
NPB
neuropeptide B
chr17_-_73636362 0.558 TMC6
transmembrane channel-like 6
chr3_-_49701085 0.557 NM_020998
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr8_+_21972631 0.556 NM_001114138
NM_001978
EPB49

erythrocyte membrane protein band 4.9 (dematin)

chr17_-_17050326 0.555 PLD6
phospholipase D family, member 6
chr9_-_139042526 0.554 NM_001606
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr17_-_17050355 0.551 NM_178836
PLD6
phospholipase D family, member 6
chr16_-_1783653 0.550 NM_001146006
NM_004970
IGFALS

insulin-like growth factor binding protein, acid labile subunit

chr16_-_5055920 0.548 C16orf89
chromosome 16 open reading frame 89

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.21 8.34e-03 GO:0045095 keratin filament

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.09 1.26e-02 GO:0005515 protein binding