Motif ID: TFDP1.p2

Z-value: 1.126


Transcription factors associated with TFDP1.p2:

Gene SymbolEntrez IDGene Name
TFDP1 7027 transcription factor Dp-1



Activity profile for motif TFDP1.p2.

activity profile for motif TFDP1.p2


Sorted Z-values histogram for motif TFDP1.p2

Sorted Z-values for motif TFDP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFDP1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_85051687 1.922 NM_020122
KCMF1
potassium channel modulatory factor 1
chr7_-_50828159 1.774 GRB10
growth factor receptor-bound protein 10
chr17_+_57909979 1.590 NM_001112707
NM_006852
TLK2

tousled-like kinase 2

chr2_-_174537354 1.582 SP3
Sp3 transcription factor
chr2_+_85051942 1.503 KCMF1
potassium channel modulatory factor 1
chr7_+_137795719 1.461 TRIM24
tripartite motif containing 24
chr22_+_18485068 1.390 RANBP1
RAN binding protein 1
chr12_+_52132353 1.386 PCBP2
poly(rC) binding protein 2
chrX_-_109448083 1.364 AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr3_-_187025438 1.334 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr22_+_18485076 1.310 RANBP1
RAN binding protein 1
chr1_+_224317030 1.283 H3F3A
H3 histone, family 3A
chr10_+_83625049 1.267 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr7_-_150305933 1.245 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr15_-_27901628 1.241 TJP1
tight junction protein 1 (zona occludens 1)
chr22_+_18485095 1.239 RANBP1
RAN binding protein 1
chr6_-_79844503 1.237 PHIP
pleckstrin homology domain interacting protein
chr6_-_13819463 1.234 RANBP9
RAN binding protein 9
chr6_+_34312906 1.227 HMGA1
high mobility group AT-hook 1
chr22_+_18485057 1.222 RANBP1
RAN binding protein 1
chr12_-_119291276 1.201 NM_002442
MSI1
musashi homolog 1 (Drosophila)
chr9_-_79835970 1.182 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr6_+_163756187 1.182 QKI
quaking homolog, KH domain RNA binding (mouse)
chr1_+_42920755 1.181 YBX1
Y box binding protein 1
chr14_-_104706159 1.178 NM_002226
NM_145159
JAG2

jagged 2

chr6_+_34313007 1.165 HMGA1
high mobility group AT-hook 1
chr7_-_151763857 1.143 MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
chr1_+_224317056 1.142 H3F3A
LOC440926
H3 histone, family 3A
H3 histone, family 3A pseudogene
chr22_+_18485145 1.135 RANBP1
RAN binding protein 1
chr7_-_50828608 1.117 NM_001001555
GRB10
growth factor receptor-bound protein 10
chr1_+_224317062 1.105 H3F3A
LOC440926
H3 histone, family 3A
H3 histone, family 3A pseudogene
chr7_+_138695537 1.096 LUC7L2
LUC7-like 2 (S. cerevisiae)
chr9_-_100510657 1.095 NM_005458
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr1_+_224317036 1.082 NM_002107
H3F3A
H3 histone, family 3A
chrX_-_109447954 1.081 AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr1_+_224317044 1.074 H3F3A
LOC440926
H3 histone, family 3A
H3 histone, family 3A pseudogene
chr2_+_181553783 1.072 UBE2E3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr19_+_1704661 1.053 NM_001080488
ONECUT3
one cut homeobox 3
chr3_+_134775404 1.048 CDV3
CDV3 homolog (mouse)
chr14_-_104705753 1.034 JAG2
jagged 2
chr22_+_49459935 1.033 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr3_-_187025501 1.033 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr1_+_42920946 1.027 YBX1
Y box binding protein 1
chr3_+_39826032 1.016 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr6_+_34312979 1.000 HMGA1
high mobility group AT-hook 1
chrX_-_109447970 0.988 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr1_-_154988045 0.987 HDGF
hepatoma-derived growth factor
chr7_+_77004686 0.986 NM_002835
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr10_+_28862429 0.982 NM_016628
NM_100486
WAC

WW domain containing adaptor with coiled-coil

chr17_-_70690525 0.981 SUMO2
SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
chr2_+_181553613 0.980 UBE2E3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr16_+_29725311 0.976 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr20_+_32045386 0.966 NM_007367
NM_016732
RALY

RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))

chr2_-_174537021 0.965 NM_001017371
SP3
Sp3 transcription factor
chr16_+_29725597 0.951


chr3_-_9413336 0.929 LOC440944
hypothetical LOC440944
chr6_-_13819931 0.924 RANBP9
RAN binding protein 9
chr1_-_154988125 0.924 NM_004494
HDGF
hepatoma-derived growth factor
chr1_-_32176275 0.917 PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr2_-_171725150 0.911 TLK1
tousled-like kinase 1
chr9_+_81377419 0.908 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr9_-_13269562 0.906 MPDZ
multiple PDZ domain protein
chr6_+_163755658 0.903 NM_006775
NM_206853
NM_206854
NM_206855
QKI



quaking homolog, KH domain RNA binding (mouse)



chr1_-_154987904 0.900 HDGF
hepatoma-derived growth factor
chr4_-_103967389 0.889 NM_181892
UBE2D3
ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chr2_+_181553333 0.885 NM_182678
NM_006357
UBE2E3

ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)

chr20_+_48241334 0.884 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr2_-_61551403 0.880 USP34
ubiquitin specific peptidase 34
chr17_+_5914364 0.875 NM_015253
WSCD1
WSC domain containing 1
chr4_+_129951877 0.871 PHF17
PHD finger protein 17
chr22_+_18484810 0.869 NM_002882
RANBP1
RAN binding protein 1
chr3_+_14964080 0.867 NM_003298
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr6_-_18095672 0.852 NM_001105566
NM_001105567
NM_001105568
NM_022113
KIF13A



kinesin family member 13A



chr4_+_38341982 0.850 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr11_+_85633908 0.849 EED
embryonic ectoderm development
chr16_+_1299637 0.843 NM_003345
NM_194259
UBE2I

ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)

chr17_+_31975611 0.839 GGNBP2
gametogenetin binding protein 2
chr6_+_163755773 0.838 QKI
quaking homolog, KH domain RNA binding (mouse)
chr21_+_37661063 0.836 DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr12_-_110521250 0.836 ATXN2
ataxin 2
chr6_+_157140895 0.835


chr19_-_18578577 0.827 CRLF1
cytokine receptor-like factor 1
chr22_+_42137955 0.826 NM_001044370
MPPED1
metallophosphoesterase domain containing 1
chr5_+_92946348 0.825 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr2_-_61551350 0.818 NM_014709
USP34
ubiquitin specific peptidase 34
chr6_-_85530617 0.818 NM_001080508
TBX18
T-box 18
chr16_+_1299654 0.815 UBE2I
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr21_+_37661728 0.814 NM_101395
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr6_-_13819622 0.812 NM_005493
RANBP9
RAN binding protein 9
chr17_-_41626032 0.810 NM_015443
KIAA1267
KIAA1267
chr16_-_27982277 0.807 NM_001109763
GSG1L
GSG1-like
chr6_-_79844658 0.806 NM_017934
PHIP
pleckstrin homology domain interacting protein
chr7_-_150306169 0.806 KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr4_-_83570318 0.805 NM_031372
HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr1_+_42920729 0.803 YBX1
Y box binding protein 1
chr2_+_153282631 0.795 NM_152522
ARL6IP6
ADP-ribosylation-like factor 6 interacting protein 6
chr6_+_37245860 0.793 NM_002648
PIM1
pim-1 oncogene
chr1_+_24944554 0.789 CLIC4
chloride intracellular channel 4
chr11_+_85633829 0.789 EED
embryonic ectoderm development
chr2_-_166940710 0.786 NM_002977
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr22_-_17799177 0.784 HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr1_-_20985734 0.783 HP1BP3
heterochromatin protein 1, binding protein 3
chr14_+_99775185 0.781 YY1
YY1 transcription factor
chr5_+_115205515 0.781 NM_001284
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr12_+_88626770 0.774 LOC338758
hypothetical LOC338758
chr2_+_176702667 0.773 NM_019558
HOXD8
homeobox D8
chr22_+_17799341 0.772 MRPL40
mitochondrial ribosomal protein L40
chr7_+_1239078 0.770 NM_001080461
UNCX
UNC homeobox
chr17_-_24357014 0.767 NM_001098635
NM_178860
SEZ6

seizure related 6 homolog (mouse)

chr1_-_32176562 0.766 NM_080391
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr4_-_15837169 0.765 TAPT1
transmembrane anterior posterior transformation 1
chr7_-_100262971 0.763 NM_004444
EPHB4
EPH receptor B4
chr1_+_177261678 0.763 NM_014864
FAM20B
family with sequence similarity 20, member B
chr6_+_157140954 0.760 ARID1B
AT rich interactive domain 1B (SWI1-like)
chr6_+_34313347 0.754 HMGA1
high mobility group AT-hook 1
chr20_-_51644187 0.746 ZNF217
zinc finger protein 217
chr16_+_1299674 0.741 UBE2I
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr1_+_42920774 0.738 YBX1
Y box binding protein 1
chr20_+_32045347 0.737 RALY
RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr22_+_42138034 0.737 MPPED1
metallophosphoesterase domain containing 1
chr6_-_79844606 0.732 PHIP
pleckstrin homology domain interacting protein
chr2_+_236067424 0.732 NM_001037131
NM_014914
AGAP1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr1_-_154988084 0.731 HDGF
hepatoma-derived growth factor
chr9_+_109085643 0.724 RAD23B
RAD23 homolog B (S. cerevisiae)
chr6_-_86409283 0.722 NM_001159674
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr6_+_163755788 0.722 QKI
quaking homolog, KH domain RNA binding (mouse)
chr6_+_43846735 0.719 VEGFA
vascular endothelial growth factor A
chr12_-_97562836 0.718 IKBIP
IKBKB interacting protein
chr7_-_20792948 0.715 SP8
Sp8 transcription factor
chr20_+_8997660 0.712 NM_001172646
PLCB4
phospholipase C, beta 4
chr16_-_47872973 0.711 CBLN1
cerebellin 1 precursor
chr1_+_42920889 0.710 YBX1
Y box binding protein 1
chr1_-_243093833 0.709 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr19_+_40451626 0.705 USF2
upstream transcription factor 2, c-fos interacting
chr22_-_20551937 0.705 MAPK1
mitogen-activated protein kinase 1
chr1_+_24944493 0.704 CLIC4
chloride intracellular channel 4
chr11_+_58103212 0.702 ZFP91-CNTF
ZFP91
ZFP91-CNTF readthrough transcript
zinc finger protein 91 homolog (mouse)
chr22_+_47350781 0.701 NM_015381
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr6_-_79844618 0.699 PHIP
pleckstrin homology domain interacting protein
chr2_-_47986160 0.696 NM_001190274
FBXO11
F-box protein 11
chr2_-_174536761 0.691 SP3
Sp3 transcription factor
chr20_+_8997791 0.691 PLCB4
phospholipase C, beta 4
chr14_+_99774854 0.686 NM_003403
YY1
YY1 transcription factor
chr12_-_56526484 0.683 CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr1_-_20985677 0.683 HP1BP3
heterochromatin protein 1, binding protein 3
chr10_+_105716925 0.682 SLK
STE20-like kinase
chr2_-_136005238 0.678 NM_032143
ZRANB3
zinc finger, RAN-binding domain containing 3
chr7_-_105712646 0.676 NM_005746
NAMPT
nicotinamide phosphoribosyltransferase
chr3_-_52694554 0.675 NM_018313
PBRM1
polybromo 1
chrX_-_20194629 0.675 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr6_+_79844267 0.675 PHIP
pleckstrin homology domain interacting protein
chr1_-_32176475 0.675 PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr4_-_15837195 0.671 NM_153365
TAPT1
transmembrane anterior posterior transformation 1
chr6_-_18372617 0.670 NM_001134709
NM_003472
DEK

DEK oncogene

chr6_+_127629677 0.669 NM_030963
RNF146
ring finger protein 146
chr7_-_148212230 0.668 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr19_-_1814546 0.664 NM_031918
KLF16
Kruppel-like factor 16
chr22_-_20551953 0.663 NM_002745
NM_138957
MAPK1

mitogen-activated protein kinase 1

chr5_-_140978751 0.663 NM_001079812
NM_005219
DIAPH1

diaphanous homolog 1 (Drosophila)

chr17_-_70690688 0.661 NM_001005849
NM_006937
SUMO2

SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)

chr17_+_31974849 0.661 NM_024835
GGNBP2
gametogenetin binding protein 2
chrX_-_17789276 0.661 NM_001172732
NM_001172739
NM_001172743
NM_021785
RAI2



retinoic acid induced 2



chr9_-_95253666 0.659 FAM120AOS
family with sequence similarity 120A opposite strand
chr12_+_19484387 0.658 AEBP2
AE binding protein 2
chr17_-_70690625 0.656 SUMO2
SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
chr6_+_34312667 0.653 HMGA1
high mobility group AT-hook 1
chr7_-_105712565 0.653 NAMPT
nicotinamide phosphoribosyltransferase
chr10_+_82203872 0.647 NM_001128309
NM_030927
TSPAN14

tetraspanin 14

chr19_+_40451720 0.647 NM_003367
NM_207291
USF2

upstream transcription factor 2, c-fos interacting

chr1_+_61320213 0.647 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr8_+_61753912 0.646 CHD7
chromodomain helicase DNA binding protein 7
chr10_+_28862514 0.643 WAC
WW domain containing adaptor with coiled-coil
chr7_+_129038815 0.643 NRF1
nuclear respiratory factor 1
chr10_+_112669349 0.643 SHOC2
soc-2 suppressor of clear homolog (C. elegans)
chr6_-_31973434 0.640 NM_006709
NM_025256
EHMT2

euchromatic histone-lysine N-methyltransferase 2

chr12_+_19484044 0.638 AEBP2
AE binding protein 2
chr11_+_32870935 0.637 NM_001076786
QSER1
glutamine and serine rich 1
chr1_-_174442987 0.633 NM_001001740
NM_022457
RFWD2

ring finger and WD repeat domain 2

chr3_+_50167424 0.632 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr17_-_39652449 0.631 NM_001076684
UBTF
upstream binding transcription factor, RNA polymerase I
chr12_+_109956210 0.629 NM_015267
CUX2
cut-like homeobox 2
chr4_-_103967784 0.626 NM_181887
NM_181891
UBE2D3

ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)

chr6_+_44346457 0.620 NM_001137560
TMEM151B
transmembrane protein 151B
chr3_-_47798279 0.618 SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr1_+_10015736 0.618 UBE4B
ubiquitination factor E4B (UFD2 homolog, yeast)
chrX_-_152749035 0.615 PDZD4
PDZ domain containing 4
chr1_+_88922424 0.614 NM_006256
PKN2
protein kinase N2
chr6_+_42858443 0.613 FLJ38717
FLJ38717 protein
chr2_-_97978421 0.613 NM_015348
TMEM131
transmembrane protein 131
chr1_-_51757490 0.609 EPS15
epidermal growth factor receptor pathway substrate 15
chr1_+_42920718 0.609 YBX1
Y box binding protein 1
chr1_-_20985747 0.608 NM_016287
HP1BP3
heterochromatin protein 1, binding protein 3
chr22_-_17799215 0.607 NM_003325
HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr9_+_81377289 0.606 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr12_+_52132154 0.603 PCBP2
poly(rC) binding protein 2
chr22_-_35113947 0.603 MYH9
myosin, heavy chain 9, non-muscle
chrX_-_150893752 0.601 NM_004961
GABRE
gamma-aminobutyric acid (GABA) A receptor, epsilon
chr4_+_140442118 0.601 NM_057175
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr5_+_65053749 0.598 NM_020726
NLN
neurolysin (metallopeptidase M3 family)
chr22_-_20551722 0.597 MAPK1
mitogen-activated protein kinase 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.12 8.56e-41 GO:0009987 cellular process
1.27 7.85e-39 GO:0044260 cellular macromolecule metabolic process
1.21 2.79e-38 GO:0044237 cellular metabolic process
1.18 1.05e-28 GO:0044238 primary metabolic process
1.21 6.34e-27 GO:0043170 macromolecule metabolic process
1.16 9.83e-27 GO:0008152 metabolic process
1.27 9.66e-21 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.28 1.29e-20 GO:0071842 cellular component organization at cellular level
1.24 8.49e-20 GO:0034641 cellular nitrogen compound metabolic process
1.23 1.21e-19 GO:0016043 cellular component organization
1.35 3.46e-19 GO:0006996 organelle organization
1.26 6.84e-19 GO:0071841 cellular component organization or biogenesis at cellular level
1.14 7.15e-19 GO:0050794 regulation of cellular process
1.23 1.38e-18 GO:0006807 nitrogen compound metabolic process
1.32 1.77e-18 GO:0006464 protein modification process
1.22 6.45e-18 GO:0071840 cellular component organization or biogenesis
1.22 3.02e-17 GO:0060255 regulation of macromolecule metabolic process
1.28 3.42e-17 GO:0090304 nucleic acid metabolic process
1.20 6.75e-17 GO:0019222 regulation of metabolic process
1.21 8.36e-17 GO:0031323 regulation of cellular metabolic process
1.13 9.66e-17 GO:0050789 regulation of biological process
1.55 1.55e-16 GO:0051276 chromosome organization
1.26 2.18e-16 GO:0044267 cellular protein metabolic process
1.21 3.59e-16 GO:0080090 regulation of primary metabolic process
1.30 4.61e-16 GO:0043412 macromolecule modification
1.11 8.00e-14 GO:0065007 biological regulation
1.58 1.13e-13 GO:0006325 chromatin organization
1.29 4.69e-13 GO:0016070 RNA metabolic process
1.64 8.26e-13 GO:0016568 chromatin modification
1.41 1.42e-12 GO:0006351 transcription, DNA-dependent
1.23 1.93e-12 GO:0048522 positive regulation of cellular process
1.22 4.32e-12 GO:0010468 regulation of gene expression
1.23 5.15e-12 GO:0044249 cellular biosynthetic process
1.23 6.84e-12 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.21 1.03e-11 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22 1.10e-11 GO:0009058 biosynthetic process
1.21 1.44e-11 GO:0051171 regulation of nitrogen compound metabolic process
1.21 1.48e-11 GO:0031326 regulation of cellular biosynthetic process
1.28 1.99e-11 GO:0034645 cellular macromolecule biosynthetic process
1.27 2.89e-11 GO:0009059 macromolecule biosynthetic process
1.21 2.99e-11 GO:0009889 regulation of biosynthetic process
1.23 1.29e-10 GO:0048523 negative regulation of cellular process
1.22 1.78e-10 GO:0051252 regulation of RNA metabolic process
1.25 2.33e-10 GO:0010467 gene expression
1.22 2.64e-10 GO:0048519 negative regulation of biological process
1.21 3.20e-10 GO:0010556 regulation of macromolecule biosynthetic process
1.27 3.54e-10 GO:0023051 regulation of signaling
1.33 1.72e-09 GO:0007049 cell cycle
1.19 2.98e-09 GO:0048518 positive regulation of biological process
1.18 5.95e-09 GO:0019538 protein metabolic process
1.33 1.07e-08 GO:0032774 RNA biosynthetic process
1.27 1.43e-08 GO:0009966 regulation of signal transduction
1.32 1.58e-08 GO:0032268 regulation of cellular protein metabolic process
1.28 1.92e-08 GO:0009893 positive regulation of metabolic process
1.32 2.82e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.30 2.84e-08 GO:0010604 positive regulation of macromolecule metabolic process
1.30 5.16e-08 GO:0051246 regulation of protein metabolic process
1.43 6.53e-08 GO:0016071 mRNA metabolic process
1.29 6.68e-08 GO:0031325 positive regulation of cellular metabolic process
1.20 9.72e-08 GO:0006355 regulation of transcription, DNA-dependent
1.54 1.55e-07 GO:0070647 protein modification by small protein conjugation or removal
1.33 5.97e-07 GO:0033554 cellular response to stress
1.38 6.82e-07 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.32 7.42e-07 GO:0016265 death
1.31 9.17e-07 GO:0010605 negative regulation of macromolecule metabolic process
1.32 9.18e-07 GO:0008219 cell death
1.56 1.18e-06 GO:0032446 protein modification by small protein conjugation
1.29 1.40e-06 GO:0009892 negative regulation of metabolic process
1.55 1.86e-06 GO:0010608 posttranscriptional regulation of gene expression
1.25 1.96e-06 GO:0033036 macromolecule localization
1.27 2.28e-06 GO:0044248 cellular catabolic process
1.36 2.50e-06 GO:0010558 negative regulation of macromolecule biosynthetic process
1.35 2.55e-06 GO:0009890 negative regulation of biosynthetic process
1.68 2.57e-06 GO:0016570 histone modification
1.40 2.79e-06 GO:0044265 cellular macromolecule catabolic process
1.67 3.59e-06 GO:0016569 covalent chromatin modification
1.35 4.00e-06 GO:0031327 negative regulation of cellular biosynthetic process
1.31 5.21e-06 GO:0051128 regulation of cellular component organization
1.55 7.18e-06 GO:0016567 protein ubiquitination
1.32 8.32e-06 GO:0051173 positive regulation of nitrogen compound metabolic process
1.29 1.31e-05 GO:0048468 cell development
1.36 1.65e-05 GO:0010629 negative regulation of gene expression
1.46 1.96e-05 GO:0018193 peptidyl-amino acid modification
1.31 1.97e-05 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.29 2.31e-05 GO:0031324 negative regulation of cellular metabolic process
1.50 2.42e-05 GO:0006366 transcription from RNA polymerase II promoter
1.28 2.55e-05 GO:0022008 neurogenesis
1.24 2.97e-05 GO:0051641 cellular localization
1.35 3.46e-05 GO:0000902 cell morphogenesis
1.34 3.66e-05 GO:0009057 macromolecule catabolic process
1.32 4.40e-05 GO:0065003 macromolecular complex assembly
1.30 5.58e-05 GO:0046907 intracellular transport
1.29 5.86e-05 GO:0022402 cell cycle process
1.43 6.06e-05 GO:0006397 mRNA processing
1.48 6.31e-05 GO:0008380 RNA splicing
1.31 6.37e-05 GO:0012501 programmed cell death
1.31 6.72e-05 GO:0006915 apoptosis
1.59 6.99e-05 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.59 6.99e-05 GO:0000398 nuclear mRNA splicing, via spliceosome
1.32 7.42e-05 GO:0030182 neuron differentiation
1.58 8.11e-05 GO:0000375 RNA splicing, via transesterification reactions
1.25 8.24e-05 GO:0010646 regulation of cell communication
1.26 8.81e-05 GO:0006793 phosphorus metabolic process
1.26 8.81e-05 GO:0006796 phosphate metabolic process
1.21 9.32e-05 GO:0007399 nervous system development
1.32 1.01e-04 GO:0051254 positive regulation of RNA metabolic process
1.33 1.14e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.37 1.29e-04 GO:0031175 neuron projection development
1.29 1.31e-04 GO:0031399 regulation of protein modification process
1.88 1.33e-04 GO:0006402 mRNA catabolic process
1.25 1.33e-04 GO:0022607 cellular component assembly
1.32 1.42e-04 GO:0032989 cellular component morphogenesis
1.93 1.50e-04 GO:0031123 RNA 3'-end processing
2.01 1.51e-04 GO:0031124 mRNA 3'-end processing
1.33 1.64e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.27 2.11e-04 GO:0048699 generation of neurons
1.20 2.17e-04 GO:0009653 anatomical structure morphogenesis
1.24 2.17e-04 GO:0008104 protein localization
1.32 2.44e-04 GO:0030030 cell projection organization
1.33 2.71e-04 GO:0000278 mitotic cell cycle
1.21 2.85e-04 GO:0009056 catabolic process
1.34 3.40e-04 GO:0051253 negative regulation of RNA metabolic process
1.34 3.50e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.35 3.75e-04 GO:0000904 cell morphogenesis involved in differentiation
1.35 4.09e-04 GO:0032990 cell part morphogenesis
1.30 4.69e-04 GO:0019220 regulation of phosphate metabolic process
1.30 4.69e-04 GO:0051174 regulation of phosphorus metabolic process
1.69 5.07e-04 GO:0006403 RNA localization
1.35 5.08e-04 GO:0048858 cell projection morphogenesis
1.34 5.45e-04 GO:0006974 response to DNA damage stimulus
1.70 6.10e-04 GO:0050657 nucleic acid transport
1.70 6.10e-04 GO:0050658 RNA transport
1.70 6.10e-04 GO:0051236 establishment of RNA localization
1.32 6.20e-04 GO:0048666 neuron development
1.29 6.83e-04 GO:0022403 cell cycle phase
1.28 8.17e-04 GO:0006468 protein phosphorylation
1.39 9.40e-04 GO:0007264 small GTPase mediated signal transduction
1.48 1.12e-03 GO:0072523 purine-containing compound catabolic process
1.23 1.13e-03 GO:0010941 regulation of cell death
1.59 1.20e-03 GO:0006417 regulation of translation
1.23 1.28e-03 GO:0042981 regulation of apoptosis
1.26 1.33e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.48 1.58e-03 GO:0006195 purine nucleotide catabolic process
2.36 1.61e-03 GO:0034968 histone lysine methylation
1.84 1.76e-03 GO:0000956 nuclear-transcribed mRNA catabolic process
1.36 1.83e-03 GO:0007409 axonogenesis
1.25 1.92e-03 GO:0009891 positive regulation of biosynthetic process
1.86 1.95e-03 GO:0006338 chromatin remodeling
1.29 1.97e-03 GO:0006396 RNA processing
1.27 2.00e-03 GO:0071844 cellular component assembly at cellular level
1.32 2.19e-03 GO:0034613 cellular protein localization
1.38 2.30e-03 GO:0034622 cellular macromolecular complex assembly
1.32 2.38e-03 GO:0070727 cellular macromolecule localization
1.20 2.43e-03 GO:0035556 intracellular signal transduction
1.29 2.56e-03 GO:0051726 regulation of cell cycle
1.22 2.61e-03 GO:0043067 regulation of programmed cell death
1.69 2.61e-03 GO:0051028 mRNA transport
1.41 2.68e-03 GO:0033043 regulation of organelle organization
1.28 2.77e-03 GO:0042325 regulation of phosphorylation
1.41 3.31e-03 GO:0006511 ubiquitin-dependent protein catabolic process
1.67 3.34e-03 GO:0006469 negative regulation of protein kinase activity
1.34 3.68e-03 GO:0048812 neuron projection morphogenesis
1.15 3.77e-03 GO:0048869 cellular developmental process
1.24 3.83e-03 GO:0045184 establishment of protein localization
1.48 3.96e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.29 4.10e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.40 4.28e-03 GO:0019941 modification-dependent protein catabolic process
1.28 5.02e-03 GO:0001932 regulation of protein phosphorylation
1.21 5.43e-03 GO:0051649 establishment of localization in cell
1.53 6.03e-03 GO:0051169 nuclear transport
1.53 6.76e-03 GO:0006913 nucleocytoplasmic transport
1.39 6.85e-03 GO:0043632 modification-dependent macromolecule catabolic process
1.34 6.91e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.10 7.66e-03 GO:0051716 cellular response to stimulus
1.35 8.22e-03 GO:0051247 positive regulation of protein metabolic process
1.38 8.67e-03 GO:0051603 proteolysis involved in cellular protein catabolic process
2.09 8.82e-03 GO:0016571 histone methylation
1.20 8.85e-03 GO:0044085 cellular component biogenesis
1.31 9.29e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.29 9.67e-03 GO:0006259 DNA metabolic process
1.27 9.69e-03 GO:0010628 positive regulation of gene expression
1.24 9.84e-03 GO:0016310 phosphorylation
1.46 1.17e-02 GO:0009154 purine ribonucleotide catabolic process
1.34 1.20e-02 GO:0007243 intracellular protein kinase cascade
1.34 1.20e-02 GO:0023014 signal transduction via phosphorylation event
1.69 1.23e-02 GO:0042176 regulation of protein catabolic process
1.22 1.25e-02 GO:0032879 regulation of localization
1.63 1.28e-02 GO:0007265 Ras protein signal transduction
1.57 1.33e-02 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.37 1.36e-02 GO:0009259 ribonucleotide metabolic process
1.37 1.51e-02 GO:0006281 DNA repair
1.61 1.53e-02 GO:0033673 negative regulation of kinase activity
1.23 1.56e-02 GO:0043933 macromolecular complex subunit organization
1.52 1.65e-02 GO:0051493 regulation of cytoskeleton organization
1.39 1.68e-02 GO:0009141 nucleoside triphosphate metabolic process
1.37 1.89e-02 GO:0044257 cellular protein catabolic process
1.10 2.00e-02 GO:0051179 localization
1.45 2.03e-02 GO:0009261 ribonucleotide catabolic process
1.24 2.08e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.23 2.14e-02 GO:0015031 protein transport
1.30 2.16e-02 GO:0043549 regulation of kinase activity
1.10 2.25e-02 GO:0032502 developmental process
1.42 2.30e-02 GO:0000165 MAPKKK cascade
1.39 2.31e-02 GO:0051270 regulation of cellular component movement
1.35 2.79e-02 GO:0044419 interspecies interaction between organisms
1.14 2.83e-02 GO:0030154 cell differentiation
1.63 2.89e-02 GO:0006401 RNA catabolic process
1.35 3.14e-02 GO:0051301 cell division
1.30 3.43e-02 GO:0045859 regulation of protein kinase activity
1.33 3.46e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.57 3.70e-02 GO:0051348 negative regulation of transferase activity
1.44 3.74e-02 GO:0009146 purine nucleoside triphosphate catabolic process
1.93 3.84e-02 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
1.29 3.92e-02 GO:0070271 protein complex biogenesis
1.43 4.33e-02 GO:0009143 nucleoside triphosphate catabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.16 2.92e-84 GO:0044424 intracellular part
1.15 1.14e-83 GO:0005622 intracellular
1.20 1.10e-71 GO:0043227 membrane-bounded organelle
1.20 1.93e-71 GO:0043231 intracellular membrane-bounded organelle
1.18 1.85e-68 GO:0043226 organelle
1.18 5.01e-68 GO:0043229 intracellular organelle
1.28 1.71e-60 GO:0005634 nucleus
1.16 4.40e-41 GO:0005737 cytoplasm
1.37 3.00e-32 GO:0044428 nuclear part
1.20 3.97e-31 GO:0044446 intracellular organelle part
1.20 4.54e-30 GO:0044422 organelle part
1.37 1.05e-26 GO:0031981 nuclear lumen
1.31 6.72e-24 GO:0070013 intracellular organelle lumen
1.17 1.86e-23 GO:0044444 cytoplasmic part
1.41 1.17e-22 GO:0005654 nucleoplasm
1.30 2.88e-22 GO:0031974 membrane-enclosed lumen
1.30 6.43e-22 GO:0043233 organelle lumen
1.04 4.79e-20 GO:0044464 cell part
1.04 5.56e-20 GO:0005623 cell
1.30 1.79e-19 GO:0005829 cytosol
1.46 6.96e-11 GO:0005694 chromosome
1.40 1.39e-10 GO:0044451 nucleoplasm part
1.16 2.72e-10 GO:0032991 macromolecular complex
1.18 2.75e-10 GO:0043234 protein complex
1.46 6.99e-09 GO:0044427 chromosomal part
1.16 2.24e-07 GO:0043228 non-membrane-bounded organelle
1.16 2.24e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.58 3.63e-07 GO:0000785 chromatin
1.21 7.94e-07 GO:0012505 endomembrane system
1.90 2.62e-06 GO:0016585 chromatin remodeling complex
1.17 5.93e-06 GO:0031090 organelle membrane
1.32 6.88e-06 GO:0015630 microtubule cytoskeleton
2.13 8.19e-06 GO:0034708 methyltransferase complex
2.13 8.19e-06 GO:0035097 histone methyltransferase complex
1.61 1.67e-05 GO:0044454 nuclear chromosome part
1.25 1.81e-05 GO:0005794 Golgi apparatus
1.43 2.66e-05 GO:0005815 microtubule organizing center
1.53 4.80e-05 GO:0000228 nuclear chromosome
1.30 2.15e-04 GO:0044431 Golgi apparatus part
1.49 2.46e-04 GO:0016604 nuclear body
1.80 3.97e-04 GO:0000790 nuclear chromatin
1.53 4.08e-04 GO:0031252 cell leading edge
1.32 5.58e-04 GO:0000139 Golgi membrane
2.09 1.30e-03 GO:0008287 protein serine/threonine phosphatase complex
1.43 1.49e-03 GO:0005635 nuclear envelope
1.47 6.58e-03 GO:0005819 spindle
1.19 7.02e-03 GO:0005783 endoplasmic reticulum
1.48 8.30e-03 GO:0070161 anchoring junction
1.50 1.02e-02 GO:0005912 adherens junction
1.40 1.58e-02 GO:0005813 centrosome
1.51 1.82e-02 GO:0000151 ubiquitin ligase complex
2.46 1.83e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
1.79 2.93e-02 GO:0016605 PML body
1.88 4.25e-02 GO:0000792 heterochromatin
2.03 4.79e-02 GO:0005913 cell-cell adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.20 1.08e-48 GO:0005515 protein binding
1.11 1.06e-43 GO:0005488 binding
1.25 5.80e-24 GO:0003676 nucleic acid binding
1.28 4.03e-19 GO:0000166 nucleotide binding
1.24 1.35e-14 GO:0003677 DNA binding
1.25 2.40e-10 GO:0016740 transferase activity
1.37 3.69e-10 GO:0003723 RNA binding
1.68 9.66e-10 GO:0019787 small conjugating protein ligase activity
1.63 1.26e-09 GO:0016881 acid-amino acid ligase activity
1.58 5.49e-09 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.12 6.15e-09 GO:0003824 catalytic activity
1.31 8.05e-09 GO:0030528 transcription regulator activity
1.22 1.01e-08 GO:0035639 purine ribonucleoside triphosphate binding
1.22 1.34e-08 GO:0032553 ribonucleotide binding
1.22 1.34e-08 GO:0032555 purine ribonucleotide binding
1.22 1.72e-08 GO:0017076 purine nucleotide binding
1.63 1.23e-07 GO:0004842 ubiquitin-protein ligase activity
1.30 1.74e-07 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.34 2.23e-07 GO:0019899 enzyme binding
1.22 4.23e-07 GO:0030554 adenyl nucleotide binding
1.23 4.25e-07 GO:0032559 adenyl ribonucleotide binding
1.23 5.63e-07 GO:0005524 ATP binding
1.42 7.06e-07 GO:0016874 ligase activity
1.18 1.06e-05 GO:0008270 zinc ion binding
1.29 2.97e-05 GO:0016301 kinase activity
1.38 4.11e-05 GO:0004674 protein serine/threonine kinase activity
1.30 7.59e-05 GO:0043565 sequence-specific DNA binding
1.44 7.63e-05 GO:0016563 transcription activator activity
1.53 1.83e-04 GO:0019901 protein kinase binding
1.24 2.02e-04 GO:0001071 nucleic acid binding transcription factor activity
1.24 2.02e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.28 2.55e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.15 2.64e-04 GO:0046914 transition metal ion binding
1.35 3.23e-04 GO:0019904 protein domain specific binding
1.29 5.79e-04 GO:0004672 protein kinase activity
1.10 2.26e-03 GO:0046872 metal ion binding
1.44 2.40e-03 GO:0019900 kinase binding
2.10 5.01e-03 GO:0018024 histone-lysine N-methyltransferase activity
1.10 5.13e-03 GO:0043169 cation binding
1.10 5.28e-03 GO:0043167 ion binding
1.46 8.41e-03 GO:0010843 promoter binding
1.45 1.03e-02 GO:0000975 regulatory region DNA binding
1.45 1.03e-02 GO:0001067 regulatory region nucleic acid binding
1.45 1.03e-02 GO:0044212 transcription regulatory region DNA binding
1.33 1.08e-02 GO:0000988 protein binding transcription factor activity
1.33 1.08e-02 GO:0000989 transcription factor binding transcription factor activity
1.95 1.12e-02 GO:0042054 histone methyltransferase activity
1.32 1.45e-02 GO:0003712 transcription cofactor activity
1.99 2.29e-02 GO:0016278 lysine N-methyltransferase activity
1.99 2.29e-02 GO:0016279 protein-lysine N-methyltransferase activity
1.70 4.62e-02 GO:0047485 protein N-terminus binding