Motif ID: ZBTB6.p2

Z-value: 0.995


Transcription factors associated with ZBTB6.p2:

Gene SymbolEntrez IDGene Name
ZBTB6 10773 zinc finger and BTB domain containing 6



Activity profile for motif ZBTB6.p2.

activity profile for motif ZBTB6.p2


Sorted Z-values histogram for motif ZBTB6.p2

Sorted Z-values for motif ZBTB6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB6.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_51200347 1.717 NM_000424
KRT5
keratin 5
chr3_+_10832867 1.592 NM_014229
SLC6A11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr8_+_63324053 1.426 NM_173688
NKAIN3
Na+/K+ transporting ATPase interacting 3
chr5_-_149662640 1.302 NM_001012301
ARSI
arylsulfatase family, member I
chr12_-_51132129 1.231 NM_005555
KRT6B
keratin 6B
chr3_-_62835601 1.174


chr10_+_101079099 1.167 CNNM1
cyclin M1
chr10_+_101078784 1.148 NM_020348
CNNM1
cyclin M1
chr16_+_65018316 1.142 NM_001136106
NM_001178020
NM_001197224
NM_001197225
BEAN1



brain expressed, associated with NEDD4, 1



chr5_+_79021401 1.089 NM_153610
CMYA5
cardiomyopathy associated 5
chr11_-_78829342 1.062 NM_001098816
ODZ4
odz, odd Oz/ten-m homolog 4 (Drosophila)
chr1_+_149221122 1.035 NM_003568
ANXA9
annexin A9
chr22_-_37569962 1.021 NM_014293
NPTXR
neuronal pentraxin receptor
chr20_+_13150417 1.004 NM_080826
ISM1
isthmin 1 homolog (zebrafish)
chr20_-_4177519 0.956 NM_000678
ADRA1D
adrenergic, alpha-1D-, receptor
chr19_-_40693176 0.936 NM_001126059
DMKN
dermokine
chr12_-_51173238 0.933 NM_005554
KRT6A
keratin 6A
chr19_+_38485583 0.908 LOC80054
hypothetical LOC80054
chr22_+_22703107 0.896 NM_001144931
LOC391322
D-dopachrome tautomerase-like
chr2_+_220017617 0.889 SPEG
SPEG complex locus
chr12_-_51153788 0.875 NM_173086
KRT6C
keratin 6C
chr19_+_44697592 0.871 NM_182704
SELV
selenoprotein V
chr8_+_104582151 0.864 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr2_-_233060774 0.847 NM_004826
ECEL1
endothelin converting enzyme-like 1
chr5_+_139155569 0.845 NM_032289
PSD2
pleckstrin and Sec7 domain containing 2
chr1_-_240754620 0.835 NM_152666
PLD5
phospholipase D family, member 5
chr12_-_6354650 0.800 NM_001159576
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr22_+_31527678 0.795 TIMP3
TIMP metallopeptidase inhibitor 3
chr22_+_31527744 0.794 TIMP3
TIMP metallopeptidase inhibitor 3
chr17_+_52026058 0.794 NM_005450
NOG
noggin
chr22_-_45311730 0.792 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr6_+_1257674 0.760 NM_033260
FOXQ1
forkhead box Q1
chr13_+_92677012 0.738 NM_005708
GPC6
glypican 6
chr12_-_6354818 0.737 SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr10_-_99780574 0.725 NM_018058
CRTAC1
cartilage acidic protein 1
chr16_-_52876390 0.680 IRX3
iroquois homeobox 3
chr16_-_66007650 0.673 NM_013304
ZDHHC1
zinc finger, DHHC-type containing 1
chr6_+_21701942 0.657 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr4_+_61749540 0.656 LPHN3
latrophilin 3
chr1_+_156417302 0.656 CD1D
CD1d molecule
chr9_+_34948320 0.655 KIAA1045
KIAA1045
chr2_+_220200530 0.653 NM_005070
NM_201574
SLC4A3

solute carrier family 4, anion exchanger, member 3

chr22_-_31784328 0.647 NM_001135774
SYN3
synapsin III
chrX_+_118776572 0.636 NM_001105576
ANKRD58
ankyrin repeat domain 58
chr20_+_60918836 0.628 NM_001853
COL9A3
collagen, type IX, alpha 3
chr2_+_111206620 0.627 NM_001142807
ACOXL
acyl-CoA oxidase-like
chr1_-_48235148 0.626 NM_001194986
LOC388630
UPF0632 protein A
chr10_+_120779217 0.618 NM_199461
NANOS1
nanos homolog 1 (Drosophila)
chr3_-_48675321 0.612 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr17_-_1478293 0.604 SLC43A2
solute carrier family 43, member 2
chr1_+_13782838 0.581 NM_006474
NM_198389
PDPN

podoplanin

chr11_-_75056761 0.576 MAP6
microtubule-associated protein 6
chr20_-_9767406 0.574 NM_020341
NM_177990
PAK7

p21 protein (Cdc42/Rac)-activated kinase 7

chr2_-_220144254 0.561 OBSL1
obscurin-like 1
chr15_-_63457378 0.558 NM_004884
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chr15_+_43209422 0.556 NM_017434
NM_175940
DUOX1

dual oxidase 1

chr22_-_37569679 0.549


chr12_-_79855580 0.549 LIN7A
lin-7 homolog A (C. elegans)
chr6_+_30958672 0.540 DDR1
discoidin domain receptor tyrosine kinase 1
chr16_+_22732982 0.540 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr19_+_62703136 0.539 ZNF773
zinc finger protein 773
chr3_-_13896618 0.527 NM_004625
WNT7A
wingless-type MMTV integration site family, member 7A
chr17_+_77110011 0.526 NM_001077182
NM_012418
FSCN2

fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)

chr19_-_14951349 0.521 SLC1A6
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr3_+_161426322 0.521 LOC401097
hypothetical protein LOC401097
chr13_+_27392136 0.519 NM_000209
PDX1
pancreatic and duodenal homeobox 1
chr10_-_105604942 0.518 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr18_+_46340400 0.518 NM_002747
MAPK4
mitogen-activated protein kinase 4
chr12_-_79855618 0.515 NM_004664
LIN7A
lin-7 homolog A (C. elegans)
chr17_+_7549138 0.513 NM_001406
EFNB3
ephrin-B3
chr11_-_75057062 0.509 NM_033063
NM_207577
MAP6

microtubule-associated protein 6

chr4_+_1764802 0.504 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chrX_+_68752635 0.504 NM_001005609
NM_001005610
NM_001005612
NM_001005613
NM_001399
EDA




ectodysplasin A




chr17_+_45965044 0.501 NM_017957
EPN3
epsin 3
chr12_+_131774225 0.500 NM_018663
PXMP2
peroxisomal membrane protein 2, 22kDa
chr11_-_64368616 0.496 NM_017525
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr12_+_52634950 0.494 NM_173860
HOXC12
homeobox C12
chrX_+_17303458 0.494 NM_198270
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr6_+_41148665 0.494 NM_002505
NM_021705
NFYA

nuclear transcription factor Y, alpha

chr2_-_230287442 0.490 NM_139072
DNER
delta/notch-like EGF repeat containing
chr15_+_78483624 0.487 NM_014862
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr10_+_75343352 0.482 PLAU
plasminogen activator, urokinase
chr17_+_45965076 0.482 EPN3
epsin 3
chr16_+_30952382 0.480 NM_004604
STX4
syntaxin 4
chr1_+_20751518 0.477 NM_207334
FAM43B
family with sequence similarity 43, member B
chr1_-_2451543 0.475 NM_001010926
HES5
hairy and enhancer of split 5 (Drosophila)
chr3_-_159306532 0.473 NM_001163678
NM_003030
NM_006884
SHOX2


short stature homeobox 2


chr2_-_96899396 0.473 NM_017789
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr2_-_86889029 0.472 NM_001145873
CD8A
CD8a molecule
chr12_-_94860504 0.469 NM_182496
CCDC38
coiled-coil domain containing 38
chr14_+_73073570 0.468 NM_001037161
ACOT1
acyl-CoA thioesterase 1
chr16_-_71650034 0.467 NM_001164766
ZFHX3
zinc finger homeobox 3
chr16_+_22733307 0.464 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr2_+_233448739 0.461 C2orf82
chromosome 2 open reading frame 82
chr3_+_197427779 0.460 NM_152672
OSTalpha
organic solute transporter alpha
chr16_-_65838894 0.453 FHOD1
formin homology 2 domain containing 1
chr11_-_35503720 0.452 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr16_+_30952350 0.452 STX4
syntaxin 4
chr2_-_19421852 0.452 NM_145260
OSR1
odd-skipped related 1 (Drosophila)
chr17_+_31082791 0.451 NM_033315
RASL10B
RAS-like, family 10, member B
chr14_-_37134191 0.446 NM_004496
FOXA1
forkhead box A1
chr11_+_63815348 0.446 NM_033310
KCNK4
potassium channel, subfamily K, member 4
chr21_+_44169706 0.446 NM_001037553
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr10_-_76829857 0.442 ZNF503
zinc finger protein 503
chr16_+_2954217 0.440 NM_024507
NM_172229
KREMEN2

kringle containing transmembrane protein 2

chr22_+_48740432 0.438 PIM3
pim-3 oncogene
chr18_-_22382497 0.438 NM_001142730
KCTD1
potassium channel tetramerisation domain containing 1
chrX_+_17303798 0.437 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr22_+_29848923 0.436 NM_001002837
INPP5J
inositol polyphosphate-5-phosphatase J
chr18_+_40513889 0.429 NM_001130110
SETBP1
SET binding protein 1
chr6_+_41148691 0.428 NFYA
nuclear transcription factor Y, alpha
chr2_+_120018494 0.425 NM_001029996
PCDP1
primary ciliary dyskinesia protein 1
chr6_+_1335067 0.424 NM_001452
FOXF2
forkhead box F2
chr11_-_67528103 0.422 NM_030930
UNC93B1
unc-93 homolog B1 (C. elegans)
chr17_+_40681060 0.422 LOC100133991
similar to hCG1995169
chr17_+_44927591 0.420 NM_002507
NGFR
nerve growth factor receptor
chr16_+_639278 0.420 NM_145294
WDR90
WD repeat domain 90
chr10_-_103869923 0.416 NM_001113407
LDB1
LIM domain binding 1
chr17_-_6675731 0.415 NM_053285
TEKT1
tektin 1
chr20_-_3166834 0.415 NM_001174090
SLC4A11
solute carrier family 4, sodium borate transporter, member 11
chr16_+_67698943 0.414 NM_005329
HAS3
hyaluronan synthase 3
chr8_-_38444982 0.413 FGFR1
fibroblast growth factor receptor 1
chr5_+_167889123 0.411


chr1_-_215329569 0.410 NM_206594
NM_206595
ESRRG

estrogen-related receptor gamma

chr6_+_111515341 0.410 SLC16A10
solute carrier family 16, member 10 (aromatic amino acid transporter)
chr10_-_108914277 0.409 NM_001013031
NM_052918
SORCS1

sortilin-related VPS10 domain containing receptor 1

chr17_+_6840107 0.407 NM_000697
ALOX12
arachidonate 12-lipoxygenase
chr10_+_99069007 0.406 NM_005479
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr6_+_1555679 0.405 NM_001453
FOXC1
forkhead box C1
chr8_+_63323739 0.405 NKAIN3
Na+/K+ transporting ATPase interacting 3
chr10_+_47875229 0.404 NM_001040084
NM_001098845
ANXA8L2
ANXA8
ANXA8L1
annexin A8-like 2
annexin A8
annexin A8-like 1
chr22_+_23149855 0.404 ADORA2A
adenosine A2a receptor
chr17_+_9489578 0.400 NM_153210
USP43
ubiquitin specific peptidase 43
chr19_+_62703113 0.398 NM_198542
ZNF773
zinc finger protein 773
chr3_+_161425946 0.397 NM_001168214
LOC401097
hypothetical protein LOC401097
chr17_-_39265705 0.397 MPP3
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
chr19_-_44214707 0.396


chr6_+_160689355 0.395 NM_021977
SLC22A3
solute carrier family 22 (extraneuronal monoamine transporter), member 3
chr16_-_4105703 0.394 ADCY9
adenylate cyclase 9
chr17_-_39796649 0.393 NM_198475
FAM171A2
family with sequence similarity 171, member A2
chr15_-_81175542 0.392 NM_004644
AP3B2
adaptor-related protein complex 3, beta 2 subunit
chr21_-_30234100 0.390 NM_000830
NM_175611
GRIK1

glutamate receptor, ionotropic, kainate 1

chr5_+_129268352 0.389 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr11_-_67029349 0.389 NM_001130848
NM_004910
PITPNM1

phosphatidylinositol transfer protein, membrane-associated 1

chr2_+_223244606 0.388 NM_058165
MOGAT1
monoacylglycerol O-acyltransferase 1
chr12_-_102413875 0.388 NM_198521
NM_001099336
C12orf42

chromosome 12 open reading frame 42

chr22_-_36153449 0.386 NM_052906
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr17_+_46067114 0.386 NM_001144070
NM_003786
ABCC3

ATP-binding cassette, sub-family C (CFTR/MRP), member 3

chr17_-_39265965 0.384 NM_001932
MPP3
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
chr19_+_1055614 0.383 NM_001039848
GPX4
glutathione peroxidase 4 (phospholipid hydroperoxidase)
chrX_-_50230329 0.379 NM_001013742
DGKK
diacylglycerol kinase, kappa
chr12_-_3472245 0.379 LOC100129223
hypothetical LOC100129223
chr11_+_110916442 0.379 NM_178834
LAYN
layilin
chr10_+_104619199 0.378 NM_020682
AS3MT
arsenic (+3 oxidation state) methyltransferase
chr20_-_62186155 0.377 NM_001007125
C20orf201
chromosome 20 open reading frame 201
chr11_+_62893836 0.377 NM_080866
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr15_-_28472854 0.376 NM_139320
NM_148911
CHRFAM7A

CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion

chr6_+_19946591 0.375


chr2_-_42873179 0.374 NM_012205
HAAO
3-hydroxyanthranilate 3,4-dioxygenase
chr17_-_31104009 0.373 NM_139285
GAS2L2
growth arrest-specific 2 like 2
chr22_-_45512794 0.372 NM_022766
CERK
ceramide kinase
chr19_+_46390980 0.371 CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr5_+_135392482 0.369 NM_000358
TGFBI
transforming growth factor, beta-induced, 68kDa
chr18_-_45975163 0.367 NM_001080467
MYO5B
myosin VB
chr5_-_146237826 0.367 PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr10_-_88116181 0.366 NM_017551
GRID1
glutamate receptor, ionotropic, delta 1
chr14_+_93710401 0.363 NM_020958
NM_058237
PPP4R4

protein phosphatase 4, regulatory subunit 4

chr16_-_86082818 0.362 NM_015144
ZCCHC14
zinc finger, CCHC domain containing 14
chr17_-_45582872 0.358 NM_032595
PPP1R9B
protein phosphatase 1, regulatory (inhibitor) subunit 9B
chr17_+_1580504 0.358 WDR81
WD repeat domain 81
chr19_+_39664706 0.357 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr7_-_44547382 0.356 NM_001101648
NM_013389
NPC1L1

NPC1 (Niemann-Pick disease, type C1, gene)-like 1

chr1_+_154605626 0.355 NM_020407
RHBG
Rh family, B glycoprotein (gene/pseudogene)
chr17_-_71385651 0.354 TRIM47
tripartite motif containing 47
chr16_-_65838813 0.354 FHOD1
formin homology 2 domain containing 1
chr5_+_135392624 0.353 TGFBI
transforming growth factor, beta-induced, 68kDa
chr19_-_18409971 0.351 NM_001170938
NM_016368
ISYNA1

inositol-3-phosphate synthase 1

chr20_+_6696744 0.350 NM_001200
BMP2
bone morphogenetic protein 2
chr5_+_175908948 0.350 NM_017675
CDHR2
cadherin-related family member 2
chr9_+_129518163 0.349 NM_144965
TTC16
tetratricopeptide repeat domain 16
chr2_+_39746525 0.349 NM_152390
TMEM178
transmembrane protein 178
chr10_+_47216925 0.347 NM_001630
ANXA8L2
ANXA8
annexin A8-like 2
annexin A8
chr10_+_116843108 0.347 NM_207303
ATRNL1
attractin-like 1
chr12_-_28016182 0.345 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr10_-_33663984 0.344 NRP1
neuropilin 1
chr9_-_103540038 0.344 GRIN3A
glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
chr7_-_96492064 0.343 NM_005221
DLX5
distal-less homeobox 5
chr10_-_46593923 0.343 NM_001040084
NM_001098845
ANXA8L2
LOC653110
ANXA8
ANXA8L1
annexin A8-like 2
hypothetical LOC653110
annexin A8
annexin A8-like 1
chr12_-_6680053 0.343 NM_153685
C12orf53
chromosome 12 open reading frame 53
chr2_+_231968578 0.341 NM_145236
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr16_-_49742008 0.341 NM_001127892
SALL1
sal-like 1 (Drosophila)
chr1_-_9111674 0.341 NM_024980
GPR157
G protein-coupled receptor 157
chr7_+_143683365 0.339 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr1_+_26376560 0.339 NM_006314
CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr16_-_67921925 0.339 NM_022341
PDF
peptide deformylase (mitochondrial)
chr9_+_130222511 0.339 NM_016174
CERCAM
cerebral endothelial cell adhesion molecule
chr2_-_220116062 0.337 NM_001195731
CHPF
chondroitin polymerizing factor
chr17_+_2627099 0.337 RAP1GAP2
RAP1 GTPase activating protein 2
chr19_-_44214972 0.335 NM_178820
FBXO27
F-box protein 27
chr16_+_1979959 0.335 NM_004209
SYNGR3
synaptogyrin 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.54 1.49e-11 GO:0007399 nervous system development
1.27 2.73e-07 GO:0007275 multicellular organismal development
1.27 2.13e-06 GO:0048856 anatomical structure development
1.29 2.47e-06 GO:0048731 system development
1.24 3.23e-06 GO:0032502 developmental process
1.54 3.67e-06 GO:0048468 cell development
1.53 8.18e-06 GO:0022008 neurogenesis
1.09 1.12e-05 GO:0009987 cellular process
1.63 2.02e-05 GO:0032989 cellular component morphogenesis
1.53 2.24e-05 GO:0048699 generation of neurons
1.13 8.36e-05 GO:0065007 biological regulation
1.31 1.01e-04 GO:0048869 cellular developmental process
1.37 1.75e-04 GO:0009653 anatomical structure morphogenesis
1.60 1.89e-04 GO:0000902 cell morphogenesis
1.31 1.92e-04 GO:0030154 cell differentiation
1.66 2.22e-04 GO:0000904 cell morphogenesis involved in differentiation
1.35 2.31e-04 GO:0023051 regulation of signaling
1.44 5.91e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.54 7.63e-04 GO:0010628 positive regulation of gene expression
1.27 7.96e-04 GO:0048519 negative regulation of biological process
1.53 8.26e-04 GO:0030182 neuron differentiation
1.21 9.07e-04 GO:0016043 cellular component organization
1.62 1.06e-03 GO:0032990 cell part morphogenesis
1.66 1.07e-03 GO:0048812 neuron projection morphogenesis
1.68 1.18e-03 GO:0007409 axonogenesis
1.62 1.26e-03 GO:0048858 cell projection morphogenesis
1.13 1.44e-03 GO:0050794 regulation of cellular process
1.62 1.60e-03 GO:0031175 neuron projection development
1.66 1.71e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.20 1.87e-03 GO:0023052 signaling
1.24 2.13e-03 GO:0071842 cellular component organization at cellular level
1.76 2.41e-03 GO:0060284 regulation of cell development
1.34 2.70e-03 GO:0009966 regulation of signal transduction
1.12 2.80e-03 GO:0050789 regulation of biological process
1.20 3.86e-03 GO:0071840 cellular component organization or biogenesis
1.66 4.87e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.51 4.93e-03 GO:0030030 cell projection organization
1.23 5.91e-03 GO:0071841 cellular component organization or biogenesis at cellular level
2.19 7.37e-03 GO:0010975 regulation of neuron projection development
1.50 1.03e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.25 1.27e-02 GO:0048523 negative regulation of cellular process
1.47 1.53e-02 GO:0045595 regulation of cell differentiation
1.22 1.56e-02 GO:0048518 positive regulation of biological process
1.44 2.32e-02 GO:2000026 regulation of multicellular organismal development
1.87 2.42e-02 GO:0045664 regulation of neuron differentiation
1.54 2.73e-02 GO:0019226 transmission of nerve impulse
1.54 2.73e-02 GO:0035637 multicellular organismal signaling
1.22 2.85e-02 GO:0048522 positive regulation of cellular process
1.88 2.92e-02 GO:0048732 gland development
1.42 3.22e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.55 3.35e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.49 3.62e-02 GO:0048666 neuron development
1.32 3.67e-02 GO:0009893 positive regulation of metabolic process
1.38 3.67e-02 GO:0050793 regulation of developmental process
1.52 3.85e-02 GO:0007417 central nervous system development
1.42 3.97e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.42 4.00e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25 4.28e-02 GO:0048583 regulation of response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.78 3.21e-06 GO:0045202 synapse
1.86 2.69e-05 GO:0044456 synapse part
1.66 2.93e-04 GO:0043005 neuron projection
1.25 8.30e-04 GO:0044459 plasma membrane part
1.51 9.01e-04 GO:0030054 cell junction
1.17 1.17e-03 GO:0005886 plasma membrane
1.93 2.18e-03 GO:0030424 axon
1.16 3.31e-03 GO:0071944 cell periphery
2.43 4.33e-03 GO:0033267 axon part
1.38 7.54e-03 GO:0042995 cell projection
1.10 1.23e-02 GO:0016020 membrane
1.70 1.45e-02 GO:0005667 transcription factor complex
2.23 1.72e-02 GO:0008021 synaptic vesicle
3.72 2.06e-02 GO:0046658 anchored to plasma membrane
1.67 4.29e-02 GO:0016323 basolateral plasma membrane
1.82 4.36e-02 GO:0030136 clathrin-coated vesicle
1.78 4.58e-02 GO:0044297 cell body

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.42 2.50e-04 GO:0030528 transcription regulator activity
1.72 5.94e-04 GO:0042578 phosphoric ester hydrolase activity
4.88 8.93e-04 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
4.88 8.93e-04 GO:0019198 transmembrane receptor protein phosphatase activity
1.54 9.05e-03 GO:0030695 GTPase regulator activity
1.35 1.17e-02 GO:0001071 nucleic acid binding transcription factor activity
1.35 1.17e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.51 1.64e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.54 1.66e-02 GO:0004674 protein serine/threonine kinase activity
1.71 2.25e-02 GO:0016791 phosphatase activity
1.60 3.33e-02 GO:0016563 transcription activator activity
1.40 3.59e-02 GO:0043565 sequence-specific DNA binding