Motif ID: ZFP161.p2

Z-value: 2.171


Transcription factors associated with ZFP161.p2:

Gene SymbolEntrez IDGene Name
ZFP161 7541 zinc finger protein 161 homolog (mouse)



Activity profile for motif ZFP161.p2.

activity profile for motif ZFP161.p2


Sorted Z-values histogram for motif ZFP161.p2

Sorted Z-values for motif ZFP161.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZFP161.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_181237210 4.899 NM_016559
PEX5L
peroxisomal biogenesis factor 5-like
chr15_-_61680003 4.000 LOC100130855
hypothetical LOC100130855
chr13_-_43259032 3.868 NM_017993
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr8_-_125809831 3.829 NM_014751
MTSS1
metastasis suppressor 1
chr2_+_207016525 3.623 NM_003812
ADAM23
ADAM metallopeptidase domain 23
chr17_-_19711580 3.311 NM_001142610
NM_014683
ULK2

unc-51-like kinase 2 (C. elegans)

chr2_+_29191711 3.272 NM_024692
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr8_-_125809559 2.757 MTSS1
metastasis suppressor 1
chr3_+_61522310 2.662 PTPRG
protein tyrosine phosphatase, receptor type, G
chr9_-_21984414 2.636 NM_058195
CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr3_+_61522219 2.597 NM_002841
PTPRG
protein tyrosine phosphatase, receptor type, G
chr2_+_149895274 2.541 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chr10_+_122206455 2.511 NM_001030059
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr10_+_105243724 2.504 NM_004210
NEURL
neuralized homolog (Drosophila)
chr13_-_31900218 2.492 NM_001079691
NM_052818
N4BP2L1

NEDD4 binding protein 2-like 1

chr3_-_55496607 2.445 WNT5A
wingless-type MMTV integration site family, member 5A
chr3_-_55496370 2.428 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr3_+_152286138 2.376 MED12L
mediator complex subunit 12-like
chr2_+_71547325 2.331 NM_001130455
NM_001130982
NM_001130983
NM_001130984
NM_001130985
NM_001130986
NM_001130987
DYSF






dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)






chr8_+_30361485 2.213 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr18_+_75825563 2.204 NM_001136180
HSBP1L1
heat shock factor binding protein 1-like 1
chr4_+_19864332 2.188 NM_004787
SLIT2
slit homolog 2 (Drosophila)
chr9_-_21984379 2.137 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr9_-_21984329 2.120 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr15_+_57517564 2.091 NM_152450
FAM81A
family with sequence similarity 81, member A
chr18_-_72336133 2.066 NM_014643
ZNF516
zinc finger protein 516
chr1_+_234372454 2.028 NM_003272
GPR137B
G protein-coupled receptor 137B
chr20_+_20296744 1.988 NM_002196
INSM1
insulinoma-associated 1
chr3_-_129024665 1.934 NM_001003794
MGLL
monoglyceride lipase
chr10_+_105027431 1.914 INA
internexin neuronal intermediate filament protein, alpha
chr22_-_30072329 1.864 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr5_-_146869613 1.852 DPYSL3
dihydropyrimidinase-like 3
chr14_+_73128162 1.849 NM_152331
ACOT4
acyl-CoA thioesterase 4
chr9_-_34579679 1.825 NM_001842
NM_147164
CNTFR

ciliary neurotrophic factor receptor

chr10_-_30065760 1.807 SVIL
supervillin
chr18_-_7107757 1.794 NM_005559
LAMA1
laminin, alpha 1
chr1_+_151917674 1.783 NM_000906
NPR1
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr17_+_8865547 1.766 NM_004822
NTN1
netrin 1
chr14_-_73106243 1.751


chr10_+_80672842 1.738 ZMIZ1
zinc finger, MIZ-type containing 1
chr16_-_71639670 1.731 NM_006885
ZFHX3
zinc finger homeobox 3
chr1_+_229829143 1.725 NM_001012957
NM_001012958
NM_001012959
NM_001164537
NM_001164538
NM_001164539
NM_001164540
NM_001164541
NM_001164542
NM_001164544
NM_001164545
NM_001164546
NM_001164547
NM_001164548
NM_001164549
NM_001164550
NM_001164551
NM_001164552
NM_001164553
NM_001164554
NM_001164555
NM_001164556
NM_018662
DISC1






















disrupted in schizophrenia 1






















chr14_+_73105618 1.717 ACOT2
acyl-CoA thioesterase 2
chr9_-_83493415 1.716 NM_005077
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr18_-_44189625 1.670 ZBTB7C
zinc finger and BTB domain containing 7C
chr14_+_103674812 1.664 NM_015656
KIF26A
kinesin family member 26A
chr5_-_107034484 1.653 NM_001962
EFNA5
ephrin-A5
chr5_-_146869811 1.648 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr10_-_105604942 1.639 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr11_-_407324 1.637 NM_001135053
NM_021805
SIGIRR

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

chr16_+_55180767 1.634 NM_005954
MT3
metallothionein 3
chr17_+_260408 1.628 NM_001013672
C17orf97
chromosome 17 open reading frame 97
chr1_-_143643324 1.622 NM_001002811
PDE4DIP
phosphodiesterase 4D interacting protein
chr22_-_39964001 1.607 CHADL
chondroadherin-like
chr2_-_39040981 1.599 LOC375196
hypothetical LOC375196
chr15_-_50375143 1.552 NM_018728
MYO5C
myosin VC
chr10_-_88720908 1.542 LOC100133190
hypothetical LOC100133190
chr2_-_40532651 1.537 SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr17_+_56832255 1.500 TBX2
T-box 2
chr12_-_24606616 1.486 NM_152989
SOX5
SRY (sex determining region Y)-box 5
chr14_+_73073570 1.483 NM_001037161
ACOT1
acyl-CoA thioesterase 1
chr10_-_126128539 1.474 NM_001146340
NKX1-2
NK1 homeobox 2
chr5_-_58370693 1.470 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr18_+_42167904 1.467 RNF165
ring finger protein 165
chr8_+_104582151 1.464 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr9_-_71476917 1.452 NM_001163
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr18_-_29412148 1.451


chr1_-_212791597 1.449 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr11_-_60819110 1.441 VWCE
von Willebrand factor C and EGF domains
chr8_+_28407613 1.426 NM_017412
FZD3
frizzled homolog 3 (Drosophila)
chr1_+_4614964 1.420 NM_001042478
NM_018836
AJAP1

adherens junctions associated protein 1

chr10_+_115793795 1.406 NM_000684
ADRB1
adrenergic, beta-1-, receptor
chr4_+_145786622 1.406 NM_022475
HHIP
hedgehog interacting protein
chr3_-_185025989 1.366 NM_024871
MAP6D1
MAP6 domain containing 1
chr11_-_1549719 1.334 NM_004420
DUSP8
dual specificity phosphatase 8
chr15_+_92575767 1.331 MCTP2
multiple C2 domains, transmembrane 2
chr19_+_41788065 1.330 ZNF382
zinc finger protein 382
chr11_+_66381077 1.302 LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr15_+_73074882 1.295 NM_001178111
NM_001178112
NM_138967
SCAMP5


secretory carrier membrane protein 5


chr6_+_124166767 1.294 NM_001040214
NM_153355
NKAIN2

Na+/K+ transporting ATPase interacting 2

chr3_-_53055078 1.286 NM_001005158
NM_016329
SFMBT1

Scm-like with four mbt domains 1

chr15_-_69194854 1.280 NM_001102658
CT62
cancer/testis antigen 62
chr6_+_17210467 1.277 NM_001190766
FLJ23152
hypothetical protein LOC401236
chr13_-_32822759 1.269 STARD13
StAR-related lipid transfer (START) domain containing 13
chr7_-_27149750 1.266 NM_019102
HOXA5
homeobox A5
chr12_+_93066370 1.260 NM_005761
PLXNC1
plexin C1
chr19_+_58733144 1.257 NM_001079906
ZNF331
zinc finger protein 331
chr19_+_41788042 1.256 NM_032825
ZNF382
zinc finger protein 382
chr20_-_56523251 1.255 NM_153360
APCDD1L
adenomatosis polyposis coli down-regulated 1-like
chr13_+_24152548 1.247 NM_001185085
NM_001676
ATP12A

ATPase, H+/K+ transporting, nongastric, alpha polypeptide

chr10_+_60606352 1.242 NM_032439
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr11_+_128751044 1.240 NM_003658
BARX2
BARX homeobox 2
chr1_+_35811557 1.240 NM_178548
TFAP2E
transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
chr1_+_208568811 1.226 NM_001170587
NM_001170588
NM_018194
HHAT


hedgehog acyltransferase


chr8_+_65656164 1.218 BHLHE22
basic helix-loop-helix family, member e22
chr3_-_129023850 1.213 NM_007283
MGLL
monoglyceride lipase
chr4_+_72271218 1.201 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr15_+_97462675 1.200 NM_015286
NM_145728
SYNM

synemin, intermediate filament protein

chr7_+_78920846 1.197 LOC100505881
hypothetical LOC100505881
chr14_+_76297885 1.193 NM_014909
VASH1
vasohibin 1
chr7_-_27136876 1.187 NM_002141
HOXA4
homeobox A4
chr14_+_73105515 1.185 NM_006821
ACOT2
acyl-CoA thioesterase 2
chr8_+_120289735 1.185 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr14_+_23590939 1.180 NM_138360
LRRC16B
leucine rich repeat containing 16B
chr22_-_37969897 1.177 PDGFB
platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
chr2_-_74522534 1.177 RTKN
rhotekin
chr10_+_90629880 1.175 NM_020799
STAMBPL1
STAM binding protein-like 1
chr7_-_27180398 1.172 NM_018951
HOXA10
homeobox A10
chr3_+_99934227 1.171 NM_006100
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr19_-_41787999 1.158 NM_001145649
NM_001145650
ZNF529

zinc finger protein 529

chr2_-_96174502 1.146 DUSP2
dual specificity phosphatase 2
chr4_+_107036042 1.141 NM_001033047
NM_001184690
NM_001184691
NM_001184692
NM_001184693
NPNT




nephronectin




chr7_-_45927263 1.138 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr15_+_31390454 1.137 NM_001036
RYR3
ryanodine receptor 3
chr18_-_11138760 1.136 NM_022068
FAM38B
family with sequence similarity 38, member B
chr18_+_42168180 1.136 NM_152470
C18orf23
RNF165
chromosome 18 open reading frame 23
ring finger protein 165
chr8_-_75396016 1.132 NM_020647
JPH1
junctophilin 1
chr14_-_77034853 1.130 NM_182509
NM_199296
ISM2

isthmin 2 homolog (zebrafish)

chr2_-_139254273 1.128 NM_007226
NXPH2
neurexophilin 2
chr11_+_66547391 1.126 NM_177963
SYT12
synaptotagmin XII
chr2_+_64534774 1.122 NM_014181
HSPC159
galectin-related protein
chr6_+_41714171 1.109 NM_005586
MDFI
MyoD family inhibitor
chr1_-_109853808 1.107 NM_020703
AMIGO1
adhesion molecule with Ig-like domain 1
chr4_-_96689373 1.107 NM_003728
UNC5C
unc-5 homolog C (C. elegans)
chr6_+_107917965 1.101 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr5_-_83716346 1.100 NM_005711
EDIL3
EGF-like repeats and discoidin I-like domains 3
chr1_+_60053050 1.099 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr7_-_127788893 1.098 NM_001114726
NM_001174164
PRRT4

proline-rich transmembrane protein 4

chr8_-_89408832 1.094 NM_005941
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr10_-_60606195 1.092


chr4_+_109072120 1.090 NM_183075
CYP2U1
cytochrome P450, family 2, subfamily U, polypeptide 1
chr19_-_5291700 1.089 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr12_+_58276114 1.078 SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr6_-_5952631 1.078 NM_016588
NRN1
neuritin 1
chr8_+_1937711 1.078 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr18_-_72973698 1.077 MBP
myelin basic protein
chr17_+_56831951 1.077 NM_005994
TBX2
T-box 2
chr10_+_22580992 1.069


chr18_+_17076166 1.069 NM_001142966
GREB1L
growth regulation by estrogen in breast cancer-like
chr10_+_124211353 1.066 HTRA1
HtrA serine peptidase 1
chr17_-_25112393 1.065 SSH2
slingshot homolog 2 (Drosophila)
chr3_-_53054999 1.062 SFMBT1
Scm-like with four mbt domains 1
chr10_-_71575953 1.058 TYSND1
trypsin domain containing 1
chr10_-_131652007 1.057 NM_001005463
EBF3
early B-cell factor 3
chr5_+_140835788 1.056 PCDHGC3
protocadherin gamma subfamily C, 3
chr22_-_26527469 1.055 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr6_-_36463320 1.053 NM_016135
ETV7
ets variant 7
chr2_-_225615556 1.049 NM_014689
DOCK10
dedicator of cytokinesis 10
chr7_+_113513828 1.045 FOXP2
forkhead box P2
chrX_+_21302317 1.037 NM_001168647
NM_001168648
NM_001168649
NM_014927
CNKSR2



connector enhancer of kinase suppressor of Ras 2



chr3_+_61522922 1.034 PTPRG
protein tyrosine phosphatase, receptor type, G
chr10_+_129595289 1.033 NM_006504
PTPRE
protein tyrosine phosphatase, receptor type, E
chr8_+_76059262 1.031 NM_031461
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr9_-_91302707 1.029 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr2_-_175255717 1.023 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr9_+_101623957 1.022 NM_006981
NM_173199
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr3_+_44571600 1.016 NM_018651
NM_025169
ZNF167

zinc finger protein 167

chr2_-_74522513 1.015 RTKN
rhotekin
chrX_-_19815526 1.015 SH3KBP1
SH3-domain kinase binding protein 1
chr11_-_60819273 1.015 NM_152718
VWCE
von Willebrand factor C and EGF domains
chr18_-_72973750 1.014 NM_001025100
NM_001025101
MBP

myelin basic protein

chr9_+_86473273 1.011 NM_001018064
NM_006180
NTRK2

neurotrophic tyrosine kinase, receptor, type 2

chr2_+_104837004 1.011


chr2_-_96174865 1.011 NM_004418
DUSP2
dual specificity phosphatase 2
chr10_+_124210980 1.005 NM_002775
HTRA1
HtrA serine peptidase 1
chr9_-_4289574 1.004 GLIS3
GLIS family zinc finger 3
chr7_+_113513600 1.003 FOXP2
forkhead box P2
chr5_+_129268352 1.001 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr4_-_2905448 0.999 MFSD10
major facilitator superfamily domain containing 10
chr20_-_9767406 0.992 NM_020341
NM_177990
PAK7

p21 protein (Cdc42/Rac)-activated kinase 7

chr4_-_2905649 0.992 NM_001120
MFSD10
major facilitator superfamily domain containing 10
chr14_-_64508547 0.985 NM_198686
RAB15
RAB15, member RAS onocogene family
chr3_+_11171213 0.983 NM_001098212
HRH1
histamine receptor H1
chr3_+_135996990 0.982 EPHB1
EPH receptor B1
chr1_-_85703321 0.978 NM_012137
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr10_+_129595349 0.978 PTPRE
protein tyrosine phosphatase, receptor type, E
chr18_-_19496590 0.977 NM_173505
ANKRD29
ankyrin repeat domain 29
chr11_-_30564338 0.974 NM_001145399
MPPED2
metallophosphoesterase domain containing 2
chr13_-_71338144 0.971 DACH1
dachshund homolog 1 (Drosophila)
chr17_+_38064787 0.967 NM_016437
TUBG2
tubulin, gamma 2
chr7_+_29200850 0.966 CHN2
chimerin (chimaerin) 2
chr12_-_29827952 0.964 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr15_-_43457916 0.954 GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr5_-_37285160 0.953 NM_023073
C5orf42
chromosome 5 open reading frame 42
chr5_-_16670085 0.947 NM_001034850
FAM134B
family with sequence similarity 134, member B
chr2_+_17923404 0.944 NM_002252
KCNS3
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr5_-_101659864 0.943 NM_180991
SLCO4C1
solute carrier organic anion transporter family, member 4C1
chr11_-_78829342 0.941 NM_001098816
ODZ4
odz, odd Oz/ten-m homolog 4 (Drosophila)
chr3_-_189354510 0.940 LOC339929
hypothetical LOC339929
chr7_+_113513726 0.939 FOXP2
forkhead box P2
chr13_+_110163610 0.939 NM_198218
NM_198219
ING1

inhibitor of growth family, member 1

chr9_-_112840064 0.934 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr4_+_41057600 0.934


chr17_-_24918052 0.933 NM_198147
ABHD15
abhydrolase domain containing 15
chr9_+_128416542 0.927 NM_001174146
NM_001174147
NM_002316
LMX1B


LIM homeobox transcription factor 1, beta


chr1_+_224803226 0.918 C1orf95
chromosome 1 open reading frame 95
chr11_+_66381451 0.917 NM_024036
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr6_-_16869579 0.917 NM_000332
NM_001128164
ATXN1

ataxin 1

chr17_+_19081267 0.915 NM_001102664
NM_014964
NM_148921
EPN2


epsin 2


chr9_-_4289915 0.914 GLIS3
GLIS family zinc finger 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.62 1.56e-22 GO:0007399 nervous system development
1.33 1.63e-19 GO:0032502 developmental process
1.34 9.21e-19 GO:0007275 multicellular organismal development
1.44 8.18e-17 GO:0030154 cell differentiation
1.53 2.00e-16 GO:0009653 anatomical structure morphogenesis
1.43 2.00e-16 GO:0048869 cellular developmental process
1.68 1.21e-15 GO:0022008 neurogenesis
1.70 1.58e-15 GO:0048699 generation of neurons
1.35 3.39e-15 GO:0048731 system development
1.32 1.67e-14 GO:0048856 anatomical structure development
1.63 1.99e-13 GO:0048468 cell development
1.86 4.71e-13 GO:0000904 cell morphogenesis involved in differentiation
1.78 7.82e-13 GO:0000902 cell morphogenesis
1.85 1.18e-12 GO:0048858 cell projection morphogenesis
1.74 1.34e-12 GO:0030030 cell projection organization
1.83 2.89e-12 GO:0032990 cell part morphogenesis
1.88 4.56e-12 GO:0048812 neuron projection morphogenesis
1.84 4.84e-12 GO:0031175 neuron projection development
1.69 9.16e-12 GO:0030182 neuron differentiation
1.72 1.33e-11 GO:0032989 cellular component morphogenesis
1.89 1.62e-11 GO:0007409 axonogenesis
1.17 2.96e-11 GO:0050794 regulation of cellular process
1.86 3.05e-11 GO:0048667 cell morphogenesis involved in neuron differentiation
1.74 6.83e-11 GO:0048666 neuron development
1.41 2.41e-10 GO:0023051 regulation of signaling
1.15 2.96e-09 GO:0050789 regulation of biological process
1.91 4.25e-09 GO:0007411 axon guidance
1.41 9.41e-09 GO:0009966 regulation of signal transduction
1.13 1.22e-08 GO:0065007 biological regulation
1.49 2.75e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.63 7.61e-08 GO:0009887 organ morphogenesis
1.68 9.51e-08 GO:0007417 central nervous system development
1.87 9.97e-08 GO:0060284 regulation of cell development
1.56 3.46e-07 GO:0045595 regulation of cell differentiation
1.85 4.08e-07 GO:0022603 regulation of anatomical structure morphogenesis
1.79 1.00e-06 GO:0007389 pattern specification process
1.46 1.52e-06 GO:0050793 regulation of developmental process
1.53 2.22e-06 GO:0009790 embryo development
1.20 3.17e-06 GO:0023052 signaling
1.74 3.54e-06 GO:0007420 brain development
1.50 3.83e-06 GO:2000026 regulation of multicellular organismal development
1.58 1.18e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.45 1.31e-05 GO:0040011 locomotion
1.57 1.51e-05 GO:0051253 negative regulation of RNA metabolic process
1.08 1.70e-05 GO:0009987 cellular process
1.66 1.86e-05 GO:0009968 negative regulation of signal transduction
2.21 2.30e-05 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.23 2.95e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.19 3.21e-05 GO:0022604 regulation of cell morphogenesis
1.79 3.21e-05 GO:0035295 tube development
1.48 5.76e-05 GO:0009890 negative regulation of biosynthetic process
1.26 7.26e-05 GO:0006355 regulation of transcription, DNA-dependent
1.64 9.03e-05 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.83 1.00e-04 GO:0003002 regionalization
1.50 1.07e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.81 1.08e-04 GO:0050767 regulation of neurogenesis
1.49 1.10e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.19 1.13e-04 GO:0007165 signal transduction
1.27 1.25e-04 GO:0048513 organ development
1.59 1.47e-04 GO:0023057 negative regulation of signaling
1.75 1.58e-04 GO:0051960 regulation of nervous system development
1.89 1.61e-04 GO:0045664 regulation of neuron differentiation
1.25 1.64e-04 GO:0048523 negative regulation of cellular process
1.50 1.67e-04 GO:0010629 negative regulation of gene expression
1.47 1.68e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.59 1.71e-04 GO:0010648 negative regulation of cell communication
1.24 1.88e-04 GO:0051252 regulation of RNA metabolic process
1.57 1.99e-04 GO:0072358 cardiovascular system development
1.57 1.99e-04 GO:0072359 circulatory system development
1.64 2.27e-04 GO:0048598 embryonic morphogenesis
1.49 2.37e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27 2.38e-04 GO:0007166 cell surface receptor linked signaling pathway
1.23 2.41e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.91 3.08e-04 GO:0035239 tube morphogenesis
1.21 4.52e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.26 5.37e-04 GO:0048583 regulation of response to stimulus
1.47 5.70e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.52 5.75e-04 GO:0006935 chemotaxis
1.52 5.75e-04 GO:0042330 taxis
2.19 5.94e-04 GO:0010720 positive regulation of cell development
1.77 6.40e-04 GO:0007507 heart development
1.32 6.90e-04 GO:0051239 regulation of multicellular organismal process
2.22 7.83e-04 GO:0003007 heart morphogenesis
1.35 1.20e-03 GO:0010646 regulation of cell communication
1.21 1.39e-03 GO:0031326 regulation of cellular biosynthetic process
1.21 1.44e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.35 1.58e-03 GO:0006793 phosphorus metabolic process
1.35 1.58e-03 GO:0006796 phosphate metabolic process
1.20 1.62e-03 GO:0009889 regulation of biosynthetic process
1.17 1.62e-03 GO:0031323 regulation of cellular metabolic process
2.01 1.91e-03 GO:0030111 regulation of Wnt receptor signaling pathway
1.22 2.04e-03 GO:0048519 negative regulation of biological process
1.17 2.12e-03 GO:0080090 regulation of primary metabolic process
1.50 2.27e-03 GO:0048585 negative regulation of response to stimulus
1.65 2.50e-03 GO:0048729 tissue morphogenesis
1.43 2.52e-03 GO:0010628 positive regulation of gene expression
1.29 2.84e-03 GO:0035556 intracellular signal transduction
1.44 2.91e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.37 2.98e-03 GO:0006351 transcription, DNA-dependent
1.88 3.35e-03 GO:0009952 anterior/posterior pattern formation
1.92 3.51e-03 GO:0060562 epithelial tube morphogenesis
1.43 3.68e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.39 3.87e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.57 4.20e-03 GO:0051056 regulation of small GTPase mediated signal transduction
2.34 4.92e-03 GO:0048638 regulation of developmental growth
1.20 5.39e-03 GO:0071842 cellular component organization at cellular level
1.34 5.99e-03 GO:0009605 response to external stimulus
1.98 7.15e-03 GO:0010975 regulation of neuron projection development
1.13 7.31e-03 GO:0032501 multicellular organismal process
1.91 7.65e-03 GO:0050678 regulation of epithelial cell proliferation
1.15 7.78e-03 GO:0051716 cellular response to stimulus
1.37 8.24e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.17 8.45e-03 GO:0016043 cellular component organization
1.41 8.90e-03 GO:0051254 positive regulation of RNA metabolic process
1.55 1.06e-02 GO:0043009 chordate embryonic development
1.58 1.14e-02 GO:0045597 positive regulation of cell differentiation
2.29 1.16e-02 GO:0050770 regulation of axonogenesis
1.38 1.21e-02 GO:0006468 protein phosphorylation
1.19 1.28e-02 GO:0010468 regulation of gene expression
1.48 1.29e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.16 1.55e-02 GO:0060255 regulation of macromolecule metabolic process
1.48 1.86e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.53 1.86e-02 GO:0009792 embryo development ending in birth or egg hatching
1.19 2.07e-02 GO:0048522 positive regulation of cellular process
1.56 2.22e-02 GO:0051093 negative regulation of developmental process
1.68 2.29e-02 GO:0002009 morphogenesis of an epithelium
2.16 2.48e-02 GO:0050769 positive regulation of neurogenesis
1.18 2.72e-02 GO:0048518 positive regulation of biological process
1.47 3.14e-02 GO:0051094 positive regulation of developmental process
1.14 3.44e-02 GO:0019222 regulation of metabolic process
1.33 3.76e-02 GO:0009888 tissue development
1.22 3.84e-02 GO:0006464 protein modification process
2.58 3.99e-02 GO:0003206 cardiac chamber morphogenesis
2.79 4.12e-02 GO:0035272 exocrine system development
2.64 4.14e-02 GO:0003231 cardiac ventricle development
4.06 4.18e-02 GO:0060411 cardiac septum morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.64 4.98e-06 GO:0045202 synapse
1.25 1.40e-05 GO:0044459 plasma membrane part
1.61 2.25e-05 GO:0043005 neuron projection
1.39 6.73e-05 GO:0042995 cell projection
1.45 2.95e-04 GO:0030054 cell junction
1.06 2.83e-03 GO:0044424 intracellular part
1.06 4.25e-03 GO:0005622 intracellular
1.56 5.34e-03 GO:0044456 synapse part
1.11 6.74e-03 GO:0005634 nucleus
1.73 2.30e-02 GO:0005912 adherens junction
1.07 2.32e-02 GO:0005737 cytoplasm
1.61 3.72e-02 GO:0030135 coated vesicle
2.34 4.94e-02 GO:0030672 synaptic vesicle membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.48 1.94e-09 GO:0030528 transcription regulator activity
1.60 2.21e-09 GO:0043565 sequence-specific DNA binding
1.47 9.21e-09 GO:0001071 nucleic acid binding transcription factor activity
1.47 9.21e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
1.07 2.64e-05 GO:0005488 binding
1.56 2.76e-05 GO:0060589 nucleoside-triphosphatase regulator activity
1.57 2.99e-05 GO:0030695 GTPase regulator activity
1.52 5.99e-04 GO:0019904 protein domain specific binding
1.20 1.48e-03 GO:0003677 DNA binding
2.21 1.80e-03 GO:0019199 transmembrane receptor protein kinase activity
1.56 2.19e-03 GO:0042578 phosphoric ester hydrolase activity
1.38 2.36e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.26 1.30e-02 GO:0004714 transmembrane receptor protein tyrosine kinase activity
1.55 1.38e-02 GO:0005083 small GTPase regulator activity
1.38 1.39e-02 GO:0004672 protein kinase activity
1.33 1.53e-02 GO:0016301 kinase activity
1.53 1.92e-02 GO:0016564 transcription repressor activity
1.65 2.47e-02 GO:0000975 regulatory region DNA binding
1.65 2.47e-02 GO:0001067 regulatory region nucleic acid binding
1.65 2.47e-02 GO:0044212 transcription regulatory region DNA binding
1.73 3.02e-02 GO:0004721 phosphoprotein phosphatase activity
1.08 3.21e-02 GO:0005515 protein binding