Motif ID: Ar

Z-value: 1.766


Transcription factors associated with Ar:

Gene SymbolEntrez IDGene Name
Ar ENSMUSG00000046532.7 Ar



Activity profile for motif Ar.

activity profile for motif Ar


Sorted Z-values histogram for motif Ar

Sorted Z-values for motif Ar



Network of associatons between targets according to the STRING database.



First level regulatory network of Ar

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_5725639 6.267 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
 Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr6_+_5725812 5.772 ENSMUST00000115554.1
ENSMUST00000153942.1
 Dync1i1

dynein cytoplasmic 1 intermediate chain 1

chr11_-_98053415 4.680 ENSMUST00000017544.2
 Stac2
SH3 and cysteine rich domain 2
chr12_-_25096080 4.323 ENSMUST00000020974.6
 Id2
inhibitor of DNA binding 2
chr11_+_16752203 4.281 ENSMUST00000102884.3
ENSMUST00000020329.6
 Egfr

epidermal growth factor receptor

chr5_+_17574726 4.047 ENSMUST00000169603.1
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr3_-_113574242 3.990 ENSMUST00000142505.2
 Amy1
amylase 1, salivary
chr7_-_46179929 3.956 ENSMUST00000033123.6
 Abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr3_-_113577743 3.793 ENSMUST00000067980.5
 Amy1
amylase 1, salivary
chr3_-_113574758 3.758 ENSMUST00000106540.1
 Amy1
amylase 1, salivary
chr17_+_56764738 3.678 ENSMUST00000007747.8
 Dus3l
dihydrouridine synthase 3-like (S. cerevisiae)
chr8_+_95703037 3.445 ENSMUST00000073139.7
ENSMUST00000080666.7
 Ndrg4

N-myc downstream regulated gene 4

chr7_-_16476765 3.422 ENSMUST00000002053.8
 Npas1
neuronal PAS domain protein 1
chr1_-_173942445 3.391 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
 Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr3_+_117575268 3.387 ENSMUST00000039564.6
 4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr14_-_6973818 3.225 ENSMUST00000166618.1
 Gm6356
predicted gene 6356
chr10_-_86732409 3.181 ENSMUST00000070435.4
 Fabp3-ps1
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr3_-_84259812 3.177 ENSMUST00000107691.1
 Trim2
tripartite motif-containing 2
chr12_+_74297474 3.108 ENSMUST00000072100.3
 Dbpht2
DNA binding protein with his-thr domain
chr10_+_69534208 2.936 ENSMUST00000182439.1
ENSMUST00000092434.5
ENSMUST00000092432.5
ENSMUST00000092431.5
ENSMUST00000054167.8
ENSMUST00000047061.6
 Ank3





ankyrin 3, epithelial






Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 110 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 13.0 GO:0071286 cellular response to magnesium ion(GO:0071286)
1.1 12.0 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
1.4 5.7 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 5.5 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.9 4.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.9 4.3 GO:0070459 prolactin secretion(GO:0070459)
1.3 4.0 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.7 4.0 GO:0003350 pulmonary myocardium development(GO:0003350)
0.3 3.4 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.2 3.4 GO:0042711 maternal behavior(GO:0042711)
0.1 3.4 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.4 3.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.6 2.9 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 2.6 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 2.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.8 2.4 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 2.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 2.3 GO:0035855 megakaryocyte development(GO:0035855)
0.7 2.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.4 2.2 GO:0032196 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) transposition(GO:0032196)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 14.0 GO:0033270 paranode region of axon(GO:0033270)
4.0 12.0 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.2 5.1 GO:0005682 U5 snRNP(GO:0005682)
1.1 4.3 GO:0097487 vesicle lumen(GO:0031983) multivesicular body, internal vesicle(GO:0097487)
1.0 4.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 3.5 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.4 2.9 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 2.8 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 2.5 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 2.4 GO:0005901 caveola(GO:0005901)
0.0 2.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 2.1 GO:0002080 acrosomal membrane(GO:0002080)
0.1 2.0 GO:0032279 asymmetric synapse(GO:0032279)
0.0 1.9 GO:0034707 chloride channel complex(GO:0034707)
0.1 1.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.8 GO:0016459 myosin complex(GO:0016459)
0.0 1.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 1.7 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 1.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 80 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 12.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 11.6 GO:0030507 spectrin binding(GO:0030507)
3.8 11.5 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.1 5.4 GO:0017022 myosin binding(GO:0017022)
1.4 4.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 4.0 GO:0038191 neuropilin binding(GO:0038191)
0.1 4.0 GO:0005267 potassium channel activity(GO:0005267)
0.0 3.6 GO:0044325 ion channel binding(GO:0044325)
0.0 3.0 GO:0001047 core promoter binding(GO:0001047)
0.2 2.9 GO:0043495 protein anchor(GO:0043495)
0.0 2.9 GO:0003924 GTPase activity(GO:0003924)
0.2 2.6 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.2 2.4 GO:0005537 mannose binding(GO:0005537)
0.1 2.4 GO:0042056 chemoattractant activity(GO:0042056)
0.8 2.3 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 2.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.5 2.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 2.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.5 2.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.3 2.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.8 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 5.8 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 5.6 NABA_ECM_AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 4.3 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.1 2.6 PID_NETRIN_PATHWAY Netrin-mediated signaling events
0.1 2.4 PID_ARF6_PATHWAY Arf6 signaling events
0.0 1.9 PID_FOXO_PATHWAY FoxO family signaling
0.1 1.8 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 1.7 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.6 ST_ADRENERGIC Adrenergic Pathway
0.0 1.6 SIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 1.6 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.2 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 1.1 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.0 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 1.0 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.1 0.9 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.8 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 0.7 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 0.7 PID_ERBB2_ERBB3_PATHWAY ErbB2/ErbB3 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 11.6 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 11.5 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.1 4.1 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 3.9 REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.1 3.3 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 2.7 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.0 2.5 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.2 2.4 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.1 2.3 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.3 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.1 2.1 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.1 2.1 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.2 2.0 REACTOME_AMINE_LIGAND_BINDING_RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 2.0 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.5 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 1.2 REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.1 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.9 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.8 REACTOME_RNA_POL_III_TRANSCRIPTION_INITIATION_FROM_TYPE_3_PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.7 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling