Motif ID: Arid3a

Z-value: 0.562


Transcription factors associated with Arid3a:

Gene SymbolEntrez IDGene Name
Arid3a ENSMUSG00000019564.6 Arid3a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arid3amm10_v2_chr10_+_79927039_799271390.135.9e-01Click!


Activity profile for motif Arid3a.

activity profile for motif Arid3a


Sorted Z-values histogram for motif Arid3a

Sorted Z-values for motif Arid3a



Network of associatons between targets according to the STRING database.



First level regulatory network of Arid3a

PNG image of the network

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Top targets:


Showing 1 to 20 of 92 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_123264076 1.021 ENSMUST00000050756.7
 Fam19a2
family with sequence similarity 19, member A2
chr4_+_141368116 0.835 ENSMUST00000006380.4
 Fam131c
family with sequence similarity 131, member C
chr11_-_116654245 0.816 ENSMUST00000021166.5
 Cygb
cytoglobin
chr15_-_3583191 0.791 ENSMUST00000069451.4
 Ghr
growth hormone receptor
chr10_+_69533761 0.778 ENSMUST00000182884.1
 Ank3
ankyrin 3, epithelial
chr12_-_24493656 0.740 ENSMUST00000073088.2
 Gm16372
predicted pseudogene 16372
chr1_+_17145357 0.664 ENSMUST00000026879.7
 Gdap1
ganglioside-induced differentiation-associated-protein 1
chr4_-_87806276 0.641 ENSMUST00000148059.1
 Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chrX_+_163911401 0.620 ENSMUST00000140845.1
 Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr4_-_87806296 0.608 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr3_-_85741389 0.559 ENSMUST00000094148.4
 Fam160a1
family with sequence similarity 160, member A1
chr17_+_3532554 0.546 ENSMUST00000168560.1
 Cldn20
claudin 20
chr8_+_84415348 0.515 ENSMUST00000121390.1
ENSMUST00000122053.1
 Cacna1a

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

chrX_+_153237466 0.495 ENSMUST00000143880.1
 Klf8
Kruppel-like factor 8
chr1_+_179960472 0.478 ENSMUST00000097453.2
ENSMUST00000111117.1
 Cdc42bpa

CDC42 binding protein kinase alpha

chr18_-_6241486 0.470 ENSMUST00000025083.7
 Kif5b
kinesin family member 5B
chr12_+_4769375 0.452 ENSMUST00000178879.1
 Pfn4
profilin family, member 4
chr1_+_179961110 0.433 ENSMUST00000076687.5
ENSMUST00000097450.3
 Cdc42bpa

CDC42 binding protein kinase alpha

chr2_-_32982007 0.429 ENSMUST00000028129.7
 Slc2a8
solute carrier family 2, (facilitated glucose transporter), member 8
chr12_+_69963452 0.406 ENSMUST00000110560.1
 Gm3086
predicted gene 3086

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 1.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.9 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.2 0.8 GO:0000255 allantoin metabolic process(GO:0000255)
0.2 0.8 GO:0015671 oxygen transport(GO:0015671)
0.1 0.7 GO:0035617 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.7 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.7 GO:0060612 adipose tissue development(GO:0060612)
0.2 0.5 GO:0050883 regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.4 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.4 GO:0060025 regulation of synaptic activity(GO:0060025)
0.1 0.4 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 0.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.7 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0016235 aggresome(GO:0016235)
0.1 0.4 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)
0.0 0.3 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0002177 manchette(GO:0002177)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.1 0.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.2 0.8 GO:0004096 catalase activity(GO:0004096)
0.0 0.8 GO:0017046 peptide hormone binding(GO:0017046)
0.1 0.7 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.4 GO:0005536 glucose binding(GO:0005536)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.1 0.2 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.9 PID_CDC42_PATHWAY CDC42 signaling events
0.0 0.8 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.8 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.8 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.7 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.3 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins