Motif ID: Arid3a

Z-value: 0.562


Transcription factors associated with Arid3a:

Gene SymbolEntrez IDGene Name
Arid3a ENSMUSG00000019564.6 Arid3a

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arid3amm10_v2_chr10_+_79927039_799271390.135.9e-01Click!


Activity profile for motif Arid3a.

activity profile for motif Arid3a


Sorted Z-values histogram for motif Arid3a

Sorted Z-values for motif Arid3a



Network of associatons between targets according to the STRING database.



First level regulatory network of Arid3a

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_123264076 1.021 ENSMUST00000050756.7
 Fam19a2
family with sequence similarity 19, member A2
chr4_+_141368116 0.835 ENSMUST00000006380.4
 Fam131c
family with sequence similarity 131, member C
chr11_-_116654245 0.816 ENSMUST00000021166.5
 Cygb
cytoglobin
chr15_-_3583191 0.791 ENSMUST00000069451.4
 Ghr
growth hormone receptor
chr10_+_69533761 0.778 ENSMUST00000182884.1
 Ank3
ankyrin 3, epithelial
chr12_-_24493656 0.740 ENSMUST00000073088.2
 Gm16372
predicted pseudogene 16372
chr1_+_17145357 0.664 ENSMUST00000026879.7
 Gdap1
ganglioside-induced differentiation-associated-protein 1
chr4_-_87806276 0.641 ENSMUST00000148059.1
 Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chrX_+_163911401 0.620 ENSMUST00000140845.1
 Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr4_-_87806296 0.608 ENSMUST00000126353.1
ENSMUST00000149357.1
 Mllt3

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

chr3_-_85741389 0.559 ENSMUST00000094148.4
 Fam160a1
family with sequence similarity 160, member A1
chr17_+_3532554 0.546 ENSMUST00000168560.1
 Cldn20
claudin 20
chr8_+_84415348 0.515 ENSMUST00000121390.1
ENSMUST00000122053.1
 Cacna1a

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

chrX_+_153237466 0.495 ENSMUST00000143880.1
 Klf8
Kruppel-like factor 8
chr1_+_179960472 0.478 ENSMUST00000097453.2
ENSMUST00000111117.1
 Cdc42bpa

CDC42 binding protein kinase alpha

chr18_-_6241486 0.470 ENSMUST00000025083.7
 Kif5b
kinesin family member 5B
chr12_+_4769375 0.452 ENSMUST00000178879.1
 Pfn4
profilin family, member 4
chr1_+_179961110 0.433 ENSMUST00000076687.5
ENSMUST00000097450.3
 Cdc42bpa

CDC42 binding protein kinase alpha

chr2_-_32982007 0.429 ENSMUST00000028129.7
 Slc2a8
solute carrier family 2, (facilitated glucose transporter), member 8
chr12_+_69963452 0.406 ENSMUST00000110560.1
 Gm3086
predicted gene 3086
chr1_-_150392719 0.400 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
 BC003331


cDNA sequence BC003331


chr14_+_4339563 0.385 ENSMUST00000112778.3
 2610042L04Rik
RIKEN cDNA 2610042L04 gene
chr14_+_120275669 0.383 ENSMUST00000088419.6
ENSMUST00000167459.1
 Mbnl2

muscleblind-like 2

chr1_+_150392794 0.382 ENSMUST00000124973.2
 Tpr
translocated promoter region
chr6_+_51544513 0.366 ENSMUST00000179365.1
ENSMUST00000114439.1
 Snx10

sorting nexin 10

chr1_+_60181495 0.356 ENSMUST00000160834.1
 Nbeal1
neurobeachin like 1
chr16_-_4679703 0.355 ENSMUST00000038552.6
ENSMUST00000090480.4
 Coro7

coronin 7

chr10_-_100589205 0.353 ENSMUST00000054471.8
 4930430F08Rik
RIKEN cDNA 4930430F08 gene
chr18_+_36939178 0.344 ENSMUST00000115662.2
 Pcdha2
protocadherin alpha 2
chr11_-_98018308 0.342 ENSMUST00000107561.2
 Cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr10_+_69533803 0.336 ENSMUST00000182155.1
ENSMUST00000183169.1
ENSMUST00000183148.1
 Ank3


ankyrin 3, epithelial


chr6_+_143285988 0.314 ENSMUST00000160951.1
 D6Ertd474e
DNA segment, Chr 6, ERATO Doi 474, expressed
chr6_-_136941887 0.307 ENSMUST00000111891.1
 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr7_+_29309429 0.302 ENSMUST00000137848.1
 Dpf1
D4, zinc and double PHD fingers family 1
chr9_+_108392820 0.302 ENSMUST00000035234.4
 1700102P08Rik
RIKEN cDNA 1700102P08 gene
chr2_-_176144697 0.290 ENSMUST00000178872.1
 Gm2004
predicted gene 2004
chr5_-_70842617 0.276 ENSMUST00000031119.1
 Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr19_+_58728887 0.267 ENSMUST00000048644.5
 Pnliprp1
pancreatic lipase related protein 1
chr12_+_4769278 0.267 ENSMUST00000020967.4
 Pfn4
profilin family, member 4
chr2_-_175327598 0.258 ENSMUST00000109050.2
 Gm4631
predicted gene 4631
chr5_-_23616528 0.251 ENSMUST00000088392.4
 Srpk2
serine/arginine-rich protein specific kinase 2
chr15_-_58847321 0.249 ENSMUST00000075109.5
 Ube2d4
ubiquitin-conjugating enzyme E2D 4
chr8_-_85432841 0.248 ENSMUST00000047749.5
 4921524J17Rik
RIKEN cDNA 4921524J17 gene
chr2_+_177009681 0.242 ENSMUST00000178182.1
 Gm14419
predicted gene 14419
chr2_+_176807362 0.234 ENSMUST00000179435.1
 Gm14295
predicted gene 14295
chr11_-_80377975 0.222 ENSMUST00000179332.1
ENSMUST00000103225.4
ENSMUST00000134274.1
 5730455P16Rik


RIKEN cDNA 5730455P16 gene


chr18_-_6241470 0.220 ENSMUST00000163210.1
 Kif5b
kinesin family member 5B
chr2_-_175133322 0.209 ENSMUST00000099029.3
 Gm14399
predicted gene 14399
chr5_+_86804214 0.190 ENSMUST00000119339.1
ENSMUST00000120498.1
 Ythdc1

YTH domain containing 1

chr17_-_24936894 0.188 ENSMUST00000115228.2
ENSMUST00000117509.1
ENSMUST00000121723.1
ENSMUST00000119115.1
ENSMUST00000121787.1
ENSMUST00000088345.5
ENSMUST00000120035.1
 Mapk8ip3






mitogen-activated protein kinase 8 interacting protein 3






chr4_+_139923349 0.177 ENSMUST00000128563.1
 Gm13028
predicted gene 13028
chr3_+_32436376 0.174 ENSMUST00000108242.1
 Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr5_+_145083830 0.172 ENSMUST00000031625.8
 Arpc1a
actin related protein 2/3 complex, subunit 1A
chr17_-_24936969 0.161 ENSMUST00000178969.1
ENSMUST00000115229.3
 Mapk8ip3

mitogen-activated protein kinase 8 interacting protein 3

chr7_+_99594605 0.156 ENSMUST00000162290.1
 Arrb1
arrestin, beta 1
chr17_+_29274078 0.152 ENSMUST00000149405.2
 BC004004
cDNA sequence BC004004
chr1_+_155158703 0.143 ENSMUST00000027743.7
 Stx6
syntaxin 6
chr3_+_32436151 0.142 ENSMUST00000029201.7
 Pik3ca
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr17_+_36837123 0.136 ENSMUST00000179968.1
ENSMUST00000130367.1
ENSMUST00000130801.1
ENSMUST00000144182.1
ENSMUST00000123715.1
ENSMUST00000053434.8
 Trim26





tripartite motif-containing 26





chr10_+_79996479 0.136 ENSMUST00000132517.1
 Abca7
ATP-binding cassette, sub-family A (ABC1), member 7
chr15_+_83563571 0.133 ENSMUST00000047419.6
 Tspo
translocator protein
chr12_-_4769217 0.122 ENSMUST00000053458.5
 Fam228b
family with sequence similarity 228, member B
chr12_-_108003594 0.121 ENSMUST00000066060.4
 Bcl11b
B cell leukemia/lymphoma 11B
chr11_-_110095937 0.113 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
 Abca8a


ATP-binding cassette, sub-family A (ABC1), member 8a


chr12_-_108003414 0.112 ENSMUST00000109887.1
ENSMUST00000109891.2
 Bcl11b

B cell leukemia/lymphoma 11B

chr4_-_108071327 0.107 ENSMUST00000106701.1
 Scp2
sterol carrier protein 2, liver
chr4_-_41517326 0.097 ENSMUST00000030152.6
ENSMUST00000095126.4
 1110017D15Rik

RIKEN cDNA 1110017D15 gene

chr1_-_158958367 0.095 ENSMUST00000159861.2
 Pappa2
pappalysin 2
chr11_-_110095974 0.092 ENSMUST00000100287.2
 Abca8a
ATP-binding cassette, sub-family A (ABC1), member 8a
chr12_+_65225513 0.090 ENSMUST00000046331.4
 Wdr20b
WD repeat domain 20b
chr2_+_3770673 0.082 ENSMUST00000177037.1
 Fam107b
family with sequence similarity 107, member B
chr7_+_27452417 0.079 ENSMUST00000108357.1
 Blvrb
biliverdin reductase B (flavin reductase (NADPH))
chr9_+_54538984 0.077 ENSMUST00000060242.5
ENSMUST00000118413.1
 Sh2d7

SH2 domain containing 7

chr2_+_164460945 0.075 ENSMUST00000072452.4
 Sys1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr15_+_99006056 0.075 ENSMUST00000079818.3
 Gm8973
predicted gene 8973
chrX_-_134111852 0.072 ENSMUST00000033610.6
 Nox1
NADPH oxidase 1
chr11_+_62551676 0.067 ENSMUST00000136938.1
 Ubb
ubiquitin B
chr18_-_73754457 0.066 ENSMUST00000041138.2
 Elac1
elaC homolog 1 (E. coli)
chr6_-_136941694 0.063 ENSMUST00000032344.5
 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr11_+_5520652 0.060 ENSMUST00000063084.9
 Xbp1
X-box binding protein 1
chr3_+_30602056 0.043 ENSMUST00000047502.7
 Mynn
myoneurin
chr14_+_105681824 0.039 ENSMUST00000073238.6
 Gm10076
predicted gene 10076
chr7_+_140941550 0.038 ENSMUST00000079403.4
 Athl1
ATH1, acid trehalase-like 1 (yeast)
chr15_+_100334929 0.035 ENSMUST00000075420.4
 Mettl7a3
methyltransferase like 7A3
chr7_+_127746775 0.034 ENSMUST00000033081.7
 Fbxl19
F-box and leucine-rich repeat protein 19
chr12_+_87443896 0.023 ENSMUST00000161023.1
ENSMUST00000160488.1
ENSMUST00000077462.7
ENSMUST00000160880.1
 Slirp



SRA stem-loop interacting RNA binding protein



chr13_-_92030897 0.021 ENSMUST00000149630.1
 Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr1_-_24612700 0.018 ENSMUST00000088336.1
 Gm10222
predicted gene 10222
chr11_+_101442298 0.015 ENSMUST00000077856.6
 Rpl27
ribosomal protein L27
chr11_+_50174839 0.009 ENSMUST00000020647.3
 3010026O09Rik
RIKEN cDNA 3010026O09 gene
chr3_-_146495115 0.002 ENSMUST00000093951.2
 Spata1
spermatogenesis associated 1
chr4_+_134930898 0.002 ENSMUST00000030622.2
 Syf2
SYF2 homolog, RNA splicing factor (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0000255 allantoin metabolic process(GO:0000255)
0.2 0.5 GO:0050883 regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883)
0.2 0.8 GO:0015671 oxygen transport(GO:0015671)
0.1 0.7 GO:0035617 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.4 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 1.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.4 GO:0060025 regulation of synaptic activity(GO:0060025)
0.1 1.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.7 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.4 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.3 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.9 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:1902995 apolipoprotein A-I-mediated signaling pathway(GO:0038027) regulation of phospholipid efflux(GO:1902994) positive regulation of phospholipid efflux(GO:1902995) positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:0072592 regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.7 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.4 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 1.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.7 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 1.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.7 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.3 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0016235 aggresome(GO:0016235)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0004096 catalase activity(GO:0004096)
0.1 0.7 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.1 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.4 GO:0005536 glucose binding(GO:0005536)
0.0 0.1 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.8 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.0 0.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.8 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.8 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.9 PID_CDC42_PATHWAY CDC42 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.6 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.1 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.7 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein