Motif ID: Arnt

Z-value: 0.839


Transcription factors associated with Arnt:

Gene SymbolEntrez IDGene Name
Arnt ENSMUSG00000015522.12 Arnt

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arntmm10_v2_chr3_+_95434386_95434428-0.312.2e-01Click!


Activity profile for motif Arnt.

activity profile for motif Arnt


Sorted Z-values histogram for motif Arnt

Sorted Z-values for motif Arnt



Network of associatons between targets according to the STRING database.



First level regulatory network of Arnt

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_131110350 3.021 ENSMUST00000066849.6
ENSMUST00000106341.2
ENSMUST00000029611.7
 Lef1


lymphoid enhancer binding factor 1


chr16_+_30065333 2.506 ENSMUST00000023171.7
 Hes1
hairy and enhancer of split 1 (Drosophila)
chr5_-_106458440 2.162 ENSMUST00000086795.6
 Barhl2
BarH-like 2 (Drosophila)
chr2_+_84839395 2.075 ENSMUST00000146816.1
ENSMUST00000028469.7
 Slc43a1

solute carrier family 43, member 1

chr12_-_56535047 1.834 ENSMUST00000178477.2
 Nkx2-1
NK2 homeobox 1
chr9_-_91365778 1.819 ENSMUST00000065360.3
 Zic1
zinc finger protein of the cerebellum 1
chr9_-_91365756 1.658 ENSMUST00000034927.6
 Zic1
zinc finger protein of the cerebellum 1
chr10_+_22158566 1.605 ENSMUST00000181645.1
ENSMUST00000105522.2
 Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr4_+_125490688 1.503 ENSMUST00000030676.7
 Grik3
glutamate receptor, ionotropic, kainate 3
chr13_+_108316395 1.412 ENSMUST00000171178.1
 Depdc1b
DEP domain containing 1B
chr17_+_56040350 1.392 ENSMUST00000002914.8
 Chaf1a
chromatin assembly factor 1, subunit A (p150)
chr11_-_64436653 1.391 ENSMUST00000177999.1
 F930015N05Rik
RIKEN cDNA F930015N05 gene
chr13_+_108316332 1.389 ENSMUST00000051594.5
 Depdc1b
DEP domain containing 1B
chr17_+_27556613 1.348 ENSMUST00000117600.1
ENSMUST00000114888.3
 Hmga1

high mobility group AT-hook 1

chr17_+_27556641 1.345 ENSMUST00000119486.1
ENSMUST00000118599.1
 Hmga1

high mobility group AT-hook 1

chr4_+_101419696 1.288 ENSMUST00000131397.1
ENSMUST00000133055.1
 Ak4

adenylate kinase 4

chr17_+_27556668 1.267 ENSMUST00000117254.1
ENSMUST00000118570.1
 Hmga1

high mobility group AT-hook 1

chr5_+_75075464 1.229 ENSMUST00000160104.1
ENSMUST00000040477.3
 Gsx2

GS homeobox 2

chr5_+_115011111 1.220 ENSMUST00000031530.5
 Sppl3
signal peptide peptidase 3
chr5_-_45639501 1.216 ENSMUST00000016023.7
 Fam184b
family with sequence similarity 184, member B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 117 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.0 GO:0006284 base-excision repair(GO:0006284)
1.0 3.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.0 2.8 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.8 2.5 GO:0021557 oculomotor nerve development(GO:0021557)
0.0 2.3 GO:0007628 adult walking behavior(GO:0007628)
0.1 2.2 GO:0001709 cell fate determination(GO:0001709)
0.1 2.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.6 1.8 GO:0021759 globus pallidus development(GO:0021759)
0.1 1.6 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.1 1.5 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 1.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.4 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 1.3 GO:0046033 AMP metabolic process(GO:0046033)
0.3 1.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2 1.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 1.2 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.1 1.2 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 1.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.4 1.1 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.1 1.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 4.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.3 3.8 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.3 2.1 GO:0001740 Barr body(GO:0001740)
0.0 1.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.4 1.6 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.5 1.4 GO:0033186 CAF-1 complex(GO:0033186)
0.2 1.4 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.2 1.2 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.2 1.2 GO:0097452 GAIT complex(GO:0097452)
0.1 1.2 GO:0045120 pronucleus(GO:0045120)
0.0 1.2 GO:0016605 PML body(GO:0016605)
0.2 0.9 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.9 GO:0031519 PcG protein complex(GO:0031519)
0.3 0.8 GO:0044194 cytolytic granule(GO:0044194)
0.2 0.8 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.7 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.7 GO:0032009 early phagosome(GO:0032009)
0.1 0.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.7 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.5 3.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 2.5 GO:0008432 JUN kinase binding(GO:0008432)
0.0 2.1 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 2.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.3 1.9 GO:0043426 MRF binding(GO:0043426)
0.2 1.8 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.2 1.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.3 1.5 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.2 1.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 1.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.4 1.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.4 1.2 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.2 1.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.2 GO:1990715 mRNA CDS binding(GO:1990715)
0.4 1.1 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.0 1.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.0 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 0.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.9 GO:0031386 protein tag(GO:0031386)

Gene overrepresentation in C2:CP category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.6 PID_CMYB_PATHWAY C-MYB transcription factor network
0.1 4.5 PID_IL4_2PATHWAY IL4-mediated signaling events
0.1 2.2 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.7 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.6 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.5 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.1 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 1.1 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.9 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.9 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.1 0.8 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 0.7 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.6 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 0.3 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 0.3 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 4.0 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 3.7 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.1 3.0 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 2.6 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 2.2 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.1 2.1 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.1 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.6 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.5 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.4 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 1.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.2 REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.2 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 1.1 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 1.1 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 0.8 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 0.8 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.8 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.1 0.7 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.7 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation