ISMARA results: Atf5

Motif ID: Atf5

Z-value: 0.870

Transcription factors associated with Atf5:

Gene Symbol	Entrez ID	Gene Name
Atf5	ENSMUSG00000038539.8	Atf5

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
Atf5	mm10_v2_chr7_-_44815658_44815682	-0.44	6.9e-02	Click!

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Showing 1 to 20 of 116 entries

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_-_79164477	3.964	ENSMUST00000040019.4	Sox10	SRY-box containing gene 10
chr1_-_22805994	3.083	ENSMUST00000097808.4	Rims1	regulating synaptic membrane exocytosis 1
chr1_-_158356258	2.866	ENSMUST00000004133.8	Brinp2	bone morphogenic protein/retinoic acid inducible neural-specific 2
chr1_-_56971762	2.763	ENSMUST00000114415.3	Satb2	special AT-rich sequence binding protein 2
chr12_+_89812467	2.258	ENSMUST00000110133.2 ENSMUST00000110130.2	Nrxn3	neurexin III
chrX_+_41401128	2.040	ENSMUST00000115103.2	Gria3	glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr19_-_46327121	1.872	ENSMUST00000041391.4 ENSMUST00000096029.5	Psd	pleckstrin and Sec7 domain containing
chr16_+_43503607	1.838	ENSMUST00000126100.1 ENSMUST00000123047.1 ENSMUST00000156981.1	Zbtb20	zinc finger and BTB domain containing 20
chrX_+_41401304	1.683	ENSMUST00000076349.5	Gria3	glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr16_+_38089001	1.674	ENSMUST00000023507.6	Gsk3b	glycogen synthase kinase 3 beta
chr18_+_64254359	1.668	ENSMUST00000025477.7	St8sia3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr19_+_27217011	1.546	ENSMUST00000164746.1 ENSMUST00000172302.1	Vldlr	very low density lipoprotein receptor
chr14_+_54936456	1.452	ENSMUST00000037814.6	Cmtm5	CKLF-like MARVEL transmembrane domain containing 5
chr4_-_8239034	1.418	ENSMUST00000066674.7	Car8	carbonic anhydrase 8
chr19_+_27217357	1.407	ENSMUST00000047645.6 ENSMUST00000167487.1	Vldlr	very low density lipoprotein receptor
chrX_+_41401476	1.372	ENSMUST00000165288.1	Gria3	glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr11_+_83302641	1.342	ENSMUST00000176430.1 ENSMUST00000065692.7	Ap2b1	adaptor-related protein complex 2, beta 1 subunit
chr11_+_83302817	1.329	ENSMUST00000142680.1	Ap2b1	adaptor-related protein complex 2, beta 1 subunit
chr8_+_54954728	1.223	ENSMUST00000033915.7	Gpm6a	glycoprotein m6a
chr18_-_23041641	1.217	ENSMUST00000097651.3	Nol4	nucleolar protein 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Showing 1 to 20 of 60 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.1	GO:0001919	regulation of receptor recycling(GO:0001919)
0.8	4.0	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
0.8	3.1	GO:0010808	positive regulation of synaptic vesicle priming(GO:0010808)
0.1	3.1	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.6	3.0	GO:0034436	glycoprotein transport(GO:0034436)
0.2	2.9	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.3	2.7	GO:0099590	neurotransmitter receptor internalization(GO:0099590)
0.1	2.3	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.1	1.9	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	1.8	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.6	1.7	GO:1904339	negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.4	1.7	GO:1990743	protein sialylation(GO:1990743)
0.2	1.5	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1	1.5	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	1.4	GO:0006730	one-carbon metabolic process(GO:0006730)
0.4	1.2	GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0	1.2	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.3	1.1	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
0.1	1.1	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	1.1	GO:0048286	lung alveolus development(GO:0048286)

Gene overrepresentation in cellular_component category:

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Showing 1 to 20 of 32 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	5.1	GO:0043083	synaptic cleft(GO:0043083)
0.5	4.0	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	3.4	GO:0000118	histone deacetylase complex(GO:0000118)
0.6	3.1	GO:0098831	presynaptic active zone cytoplasmic component(GO:0098831)
0.0	3.1	GO:0042734	presynaptic membrane(GO:0042734)
0.2	3.0	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1	2.7	GO:0030131	clathrin adaptor complex(GO:0030131)
0.2	1.7	GO:1990909	Wnt signalosome(GO:1990909)
0.2	1.5	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	1.5	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1	1.0	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.1	1.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.9	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.9	GO:0044295	axonal growth cone(GO:0044295)
0.1	0.8	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.0	0.8	GO:0033270	paranode region of axon(GO:0033270)
0.1	0.7	GO:0032584	growth cone membrane(GO:0032584)
0.1	0.7	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.7	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.7	GO:0030173	integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular_function category:

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Showing 1 to 20 of 42 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	5.1	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
0.1	3.2	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	3.2	GO:0017137	Rab GTPase binding(GO:0017137)
0.1	3.1	GO:0005246	calcium channel regulator activity(GO:0005246)
1.0	3.0	GO:0034437	very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.0	2.7	GO:0030276	clathrin binding(GO:0030276)
0.1	2.5	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	1.9	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	1.9	GO:0005125	cytokine activity(GO:0005125)
0.3	1.7	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3	1.5	GO:0070699	type II activin receptor binding(GO:0070699)
0.1	1.4	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	1.3	GO:0003777	microtubule motor activity(GO:0003777)
0.4	1.2	GO:0002153	steroid receptor RNA activator RNA binding(GO:0002153)
0.0	1.2	GO:0005262	calcium channel activity(GO:0005262)
0.3	1.1	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	1.0	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.9	GO:0015386	potassium:proton antiporter activity(GO:0015386)
0.0	0.9	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.9	GO:0035591	signaling adaptor activity(GO:0035591)

Gene overrepresentation in C2:CP category:

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Showing 1 to 11 of 11 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.8	NABA_SECRETED_FACTORS	Genes encoding secreted soluble factors
0.1	4.6	PID_REELIN_PATHWAY	Reelin signaling pathway
0.0	1.2	PID_RXR_VDR_PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.8	PID_ARF6_PATHWAY	Arf6 signaling events
0.0	0.8	PID_RAC1_REG_PATHWAY	Regulation of RAC1 activity
0.0	0.7	PID_ECADHERIN_STABILIZATION_PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.7	PID_HNF3B_PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.6	PID_VEGF_VEGFR_PATHWAY	VEGF and VEGFR signaling network
0.0	0.6	PID_TRKR_PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.5	PID_HNF3A_PATHWAY	FOXA1 transcription factor network
0.0	0.2	PID_EPHA_FWDPATHWAY	EPHA forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

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Showing 1 to 13 of 13 entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	7.8	REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.3	3.1	REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1	2.1	REACTOME_N_GLYCAN_ANTENNAE_ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	1.8	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	1.5	REACTOME_NEPHRIN_INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.8	REACTOME_RNA_POL_III_TRANSCRIPTION_TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.7	REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.6	REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.5	REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.5	REACTOME_KINESINS	Genes involved in Kinesins
0.0	0.3	REACTOME_PROLACTIN_RECEPTOR_SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.2	REACTOME_PECAM1_INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.1	REACTOME_ENDOGENOUS_STEROLS	Genes involved in Endogenous sterols