Motif ID: Atoh1_Bhlhe23

Z-value: 0.390

Transcription factors associated with Atoh1_Bhlhe23:

Gene SymbolEntrez IDGene Name
Atoh1 ENSMUSG00000073043.4 Atoh1
Bhlhe23 ENSMUSG00000045493.3 Bhlhe23

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bhlhe23mm10_v2_chr2_-_180776749_1807767490.608.9e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Atoh1_Bhlhe23

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_6449571 1.385 ENSMUST00000180035.1
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr1_+_177444653 1.014 ENSMUST00000094276.3
Zbtb18
zinc finger and BTB domain containing 18
chr16_+_43235856 0.976 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr10_-_25200110 0.760 ENSMUST00000100012.2
Akap7
A kinase (PRKA) anchor protein 7
chr9_-_21918089 0.738 ENSMUST00000128442.1
ENSMUST00000119055.1
ENSMUST00000122211.1
ENSMUST00000115351.3
Rab3d



RAB3D, member RAS oncogene family



chr10_+_69706326 0.727 ENSMUST00000182992.1
Ank3
ankyrin 3, epithelial
chr9_+_72985504 0.718 ENSMUST00000156879.1
Ccpg1
cell cycle progression 1
chr3_-_126998408 0.662 ENSMUST00000182764.1
ENSMUST00000044443.8
Ank2

ankyrin 2, brain

chr9_+_72985568 0.608 ENSMUST00000150826.2
ENSMUST00000085350.4
ENSMUST00000140675.1
Ccpg1


cell cycle progression 1


chr5_+_124194894 0.556 ENSMUST00000159053.1
ENSMUST00000162577.1
Gm16338

predicted gene 16338

chr3_-_84259812 0.549 ENSMUST00000107691.1
Trim2
tripartite motif-containing 2
chr2_-_29253001 0.547 ENSMUST00000071201.4
Ntng2
netrin G2
chr1_+_15287259 0.512 ENSMUST00000175681.1
Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr5_-_66618636 0.490 ENSMUST00000162382.1
ENSMUST00000160870.1
ENSMUST00000087256.5
ENSMUST00000160103.1
ENSMUST00000162349.1
Apbb2




amyloid beta (A4) precursor protein-binding, family B, member 2




chr2_+_65930117 0.474 ENSMUST00000176109.1
Csrnp3
cysteine-serine-rich nuclear protein 3
chr2_-_52558539 0.430 ENSMUST00000102760.3
ENSMUST00000102761.2
Cacnb4

calcium channel, voltage-dependent, beta 4 subunit

chr16_+_43510267 0.427 ENSMUST00000114695.2
Zbtb20
zinc finger and BTB domain containing 20
chr3_+_118430299 0.409 ENSMUST00000180774.1
Gm26871
predicted gene, 26871
chr5_-_124187150 0.401 ENSMUST00000161938.1
Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr11_-_69602741 0.379 ENSMUST00000138694.1
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr19_-_37176055 0.375 ENSMUST00000142973.1
ENSMUST00000154376.1
Cpeb3

cytoplasmic polyadenylation element binding protein 3

chr3_+_138065052 0.372 ENSMUST00000163080.2
1110002E22Rik
RIKEN cDNA 1110002E22 gene
chr5_+_3343893 0.369 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr10_-_12923075 0.346 ENSMUST00000180529.1
B230208H11Rik
RIKEN cDNA B230208H11 gene
chr2_+_62046580 0.339 ENSMUST00000054484.8
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr8_+_25602236 0.334 ENSMUST00000146919.1
ENSMUST00000142395.1
ENSMUST00000139966.1
Whsc1l1


Wolf-Hirschhorn syndrome candidate 1-like 1 (human)


chr1_-_150392719 0.332 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
BC003331


cDNA sequence BC003331


chr2_+_62046623 0.330 ENSMUST00000112480.2
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr13_-_97747373 0.326 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr6_+_90462562 0.320 ENSMUST00000032174.5
Klf15
Kruppel-like factor 15
chr1_-_111864869 0.310 ENSMUST00000035462.5
Dsel
dermatan sulfate epimerase-like
chr13_-_97747399 0.308 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chrX_+_159708593 0.304 ENSMUST00000080394.6
Sh3kbp1
SH3-domain kinase binding protein 1
chr2_+_62046462 0.298 ENSMUST00000102735.3
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr1_+_177445660 0.294 ENSMUST00000077225.6
Zbtb18
zinc finger and BTB domain containing 18
chr6_+_17743582 0.292 ENSMUST00000000674.6
ENSMUST00000077080.2
St7

suppression of tumorigenicity 7

chr17_-_6827990 0.284 ENSMUST00000181895.1
Gm2885
predicted gene 2885
chr4_-_141598206 0.274 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
Fblim1


filamin binding LIM protein 1


chr1_-_52800371 0.267 ENSMUST00000159725.1
Inpp1
inositol polyphosphate-1-phosphatase
chr2_+_155382186 0.244 ENSMUST00000134218.1
Trp53inp2
transformation related protein 53 inducible nuclear protein 2
chr11_+_53433299 0.240 ENSMUST00000018382.6
Gdf9
growth differentiation factor 9
chr19_-_37207293 0.224 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3




cytoplasmic polyadenylation element binding protein 3




chr5_-_66618752 0.222 ENSMUST00000162366.1
Apbb2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr1_+_150392794 0.220 ENSMUST00000124973.2
Tpr
translocated promoter region
chr5_-_144223516 0.210 ENSMUST00000085701.6
Tecpr1
tectonin beta-propeller repeat containing 1
chr5_+_129096740 0.206 ENSMUST00000056617.7
ENSMUST00000156437.1
Gpr133

G protein-coupled receptor 133

chr17_+_88626549 0.192 ENSMUST00000163588.1
ENSMUST00000064035.6
Ston1

stonin 1

chrX_+_56454871 0.188 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B

chr2_+_69670100 0.184 ENSMUST00000100050.3
Klhl41
kelch-like 41
chr15_+_30172570 0.176 ENSMUST00000081728.5
Ctnnd2
catenin (cadherin associated protein), delta 2
chr11_-_35980473 0.174 ENSMUST00000018993.6
Wwc1
WW, C2 and coiled-coil domain containing 1
chr16_+_11008898 0.173 ENSMUST00000180624.1
Gm4262
predicted gene 4262
chr11_-_76577701 0.166 ENSMUST00000176179.1
Abr
active BCR-related gene
chr6_-_12749193 0.164 ENSMUST00000046121.6
ENSMUST00000172356.1
Thsd7a

thrombospondin, type I, domain containing 7A

chr11_+_31872100 0.163 ENSMUST00000020543.6
ENSMUST00000109412.2
Cpeb4

cytoplasmic polyadenylation element binding protein 4

chr15_+_84669565 0.163 ENSMUST00000171460.1
Prr5
proline rich 5 (renal)
chr11_+_120232921 0.160 ENSMUST00000122148.1
ENSMUST00000044985.7
Bahcc1

BAH domain and coiled-coil containing 1

chr8_-_106337987 0.154 ENSMUST00000067512.7
Smpd3
sphingomyelin phosphodiesterase 3, neutral
chr8_+_4243264 0.144 ENSMUST00000110996.1
Map2k7
mitogen-activated protein kinase kinase 7
chr17_+_88626569 0.144 ENSMUST00000150023.1
Ston1
stonin 1
chr14_-_16249675 0.142 ENSMUST00000022311.4
Oxsm
3-oxoacyl-ACP synthase, mitochondrial
chr8_+_94838321 0.142 ENSMUST00000034234.8
ENSMUST00000159871.1
Coq9

coenzyme Q9 homolog (yeast)

chr15_+_82256023 0.138 ENSMUST00000143238.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr4_-_41870612 0.138 ENSMUST00000179680.1
Gm21966
predicted gene, 21966
chr11_-_98329641 0.132 ENSMUST00000041685.6
Neurod2
neurogenic differentiation 2
chr2_+_150323702 0.130 ENSMUST00000133235.2
Gm10130
predicted gene 10130
chr10_-_70655934 0.129 ENSMUST00000162144.1
ENSMUST00000162793.1
Phyhipl

phytanoyl-CoA hydroxylase interacting protein-like

chr8_+_25601591 0.129 ENSMUST00000155861.1
Whsc1l1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr2_-_39065505 0.123 ENSMUST00000039165.8
Golga1
golgi autoantigen, golgin subfamily a, 1
chr11_+_58954675 0.115 ENSMUST00000047697.5
ENSMUST00000108817.3
Trim17
Hist3h2a
tripartite motif-containing 17
histone cluster 3, H2a
chr16_-_17722879 0.114 ENSMUST00000080936.6
ENSMUST00000012259.7
Med15

mediator complex subunit 15

chr13_+_37345338 0.113 ENSMUST00000021860.5
Ly86
lymphocyte antigen 86
chr1_-_155232710 0.110 ENSMUST00000035914.3
BC034090
cDNA sequence BC034090
chr6_-_148831395 0.107 ENSMUST00000145960.1
Ipo8
importin 8
chr10_-_22149270 0.102 ENSMUST00000179054.1
ENSMUST00000069372.6
E030030I06Rik

RIKEN cDNA E030030I06 gene

chr4_-_82850721 0.097 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr3_-_107333289 0.094 ENSMUST00000061772.9
Rbm15
RNA binding motif protein 15
chr2_-_39065438 0.092 ENSMUST00000112850.2
Golga1
golgi autoantigen, golgin subfamily a, 1
chr2_+_25403128 0.091 ENSMUST00000154809.1
ENSMUST00000055921.7
ENSMUST00000141567.1
Npdc1


neural proliferation, differentiation and control 1


chr16_-_31314804 0.091 ENSMUST00000115230.1
ENSMUST00000130560.1
Apod

apolipoprotein D

chr2_-_121807024 0.089 ENSMUST00000138157.1
Frmd5
FERM domain containing 5
chr18_+_74216118 0.086 ENSMUST00000025444.6
Cxxc1
CXXC finger 1 (PHD domain)
chr15_+_78913916 0.076 ENSMUST00000089378.4
Pdxp
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr7_-_141437587 0.073 ENSMUST00000172654.1
ENSMUST00000106006.1
Slc25a22

solute carrier family 25 (mitochondrial carrier, glutamate), member 22

chr9_+_78175898 0.066 ENSMUST00000180974.1
C920006O11Rik
RIKEN cDNA C920006O11 gene
chr5_-_24447587 0.063 ENSMUST00000127194.1
ENSMUST00000115033.1
ENSMUST00000123167.1
ENSMUST00000030799.8
Tmub1



transmembrane and ubiquitin-like domain containing 1



chr19_-_53371766 0.062 ENSMUST00000086887.1
Gm10197
predicted gene 10197
chr7_-_141437829 0.059 ENSMUST00000019226.7
Slc25a22
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr18_+_77185979 0.052 ENSMUST00000075290.6
St8sia5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr9_-_71896047 0.050 ENSMUST00000184448.1
Tcf12
transcription factor 12
chr15_-_76918010 0.047 ENSMUST00000048854.7
Zfp647
zinc finger protein 647
chr4_+_86053887 0.044 ENSMUST00000107178.2
ENSMUST00000048885.5
ENSMUST00000141889.1
ENSMUST00000120678.1
Adamtsl1



ADAMTS-like 1



chr4_+_127172866 0.033 ENSMUST00000106094.2
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr11_+_32642706 0.032 ENSMUST00000109366.1
Fbxw11
F-box and WD-40 domain protein 11
chr16_-_57292845 0.030 ENSMUST00000023434.8
ENSMUST00000120112.1
ENSMUST00000119407.1
Tmem30c


transmembrane protein 30C


chr2_+_21367532 0.029 ENSMUST00000055946.7
Gpr158
G protein-coupled receptor 158
chr11_+_73160403 0.022 ENSMUST00000006104.3
P2rx5
purinergic receptor P2X, ligand-gated ion channel, 5
chr10_+_59879617 0.017 ENSMUST00000142819.1
ENSMUST00000020309.6
Dnajb12

DnaJ (Hsp40) homolog, subfamily B, member 12

chr18_+_55057557 0.012 ENSMUST00000181765.1
Gm4221
predicted gene 4221
chr11_+_49247462 0.009 ENSMUST00000109194.1
Mgat1
mannoside acetylglucosaminyltransferase 1
chr5_-_66618772 0.005 ENSMUST00000162994.1
ENSMUST00000159512.1
ENSMUST00000159786.1
Apbb2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr15_+_25622525 0.003 ENSMUST00000110457.1
ENSMUST00000137601.1
Myo10

myosin X

chr5_-_28210168 0.003 ENSMUST00000117098.1
Cnpy1
canopy 1 homolog (zebrafish)

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2 0.6 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.7 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.8 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.4 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.7 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.2 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.7 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.4 GO:0044838 cell quiescence(GO:0044838)
0.0 0.2 GO:0042701 progesterone secretion(GO:0042701)
0.0 0.4 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 1.0 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 1.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097) negative regulation of lymphocyte migration(GO:2000402)
0.0 0.2 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.0 0.3 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.2 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 1.1 GO:0021766 hippocampus development(GO:0021766)
0.0 0.1 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0097441 basilar dendrite(GO:0097441)
0.1 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.7 GO:0042588 zymogen granule(GO:0042588)
0.0 0.8 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.3 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.8 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.3 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.1 1.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.8 GO:0016208 AMP binding(GO:0016208)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.4 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions