Motif ID: Atoh1_Bhlhe23

Z-value: 0.390

Transcription factors associated with Atoh1_Bhlhe23:

Gene SymbolEntrez IDGene Name
Atoh1 ENSMUSG00000073043.4 Atoh1
Bhlhe23 ENSMUSG00000045493.3 Bhlhe23

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bhlhe23mm10_v2_chr2_-_180776749_1807767490.608.9e-03Click!


Activity profile for motif Atoh1_Bhlhe23.

activity profile for motif Atoh1_Bhlhe23


Sorted Z-values histogram for motif Atoh1_Bhlhe23

Sorted Z-values for motif Atoh1_Bhlhe23



Network of associatons between targets according to the STRING database.



First level regulatory network of Atoh1_Bhlhe23

PNG image of the network

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Top targets:


Showing 1 to 20 of 103 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_6449571 1.385 ENSMUST00000180035.1
 Tmem181b-ps
transmembrane protein 181B, pseudogene
chr1_+_177444653 1.014 ENSMUST00000094276.3
 Zbtb18
zinc finger and BTB domain containing 18
chr16_+_43235856 0.976 ENSMUST00000146708.1
 Zbtb20
zinc finger and BTB domain containing 20
chr10_-_25200110 0.760 ENSMUST00000100012.2
 Akap7
A kinase (PRKA) anchor protein 7
chr9_-_21918089 0.738 ENSMUST00000128442.1
ENSMUST00000119055.1
ENSMUST00000122211.1
ENSMUST00000115351.3
 Rab3d



RAB3D, member RAS oncogene family



chr10_+_69706326 0.727 ENSMUST00000182992.1
 Ank3
ankyrin 3, epithelial
chr9_+_72985504 0.718 ENSMUST00000156879.1
 Ccpg1
cell cycle progression 1
chr3_-_126998408 0.662 ENSMUST00000182764.1
ENSMUST00000044443.8
 Ank2

ankyrin 2, brain

chr9_+_72985568 0.608 ENSMUST00000150826.2
ENSMUST00000085350.4
ENSMUST00000140675.1
 Ccpg1


cell cycle progression 1


chr5_+_124194894 0.556 ENSMUST00000159053.1
ENSMUST00000162577.1
 Gm16338

predicted gene 16338

chr3_-_84259812 0.549 ENSMUST00000107691.1
 Trim2
tripartite motif-containing 2
chr2_-_29253001 0.547 ENSMUST00000071201.4
 Ntng2
netrin G2
chr1_+_15287259 0.512 ENSMUST00000175681.1
 Kcnb2
potassium voltage gated channel, Shab-related subfamily, member 2
chr5_-_66618636 0.490 ENSMUST00000162382.1
ENSMUST00000160870.1
ENSMUST00000087256.5
ENSMUST00000160103.1
ENSMUST00000162349.1
 Apbb2




amyloid beta (A4) precursor protein-binding, family B, member 2




chr2_+_65930117 0.474 ENSMUST00000176109.1
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr2_-_52558539 0.430 ENSMUST00000102760.3
ENSMUST00000102761.2
 Cacnb4

calcium channel, voltage-dependent, beta 4 subunit

chr16_+_43510267 0.427 ENSMUST00000114695.2
 Zbtb20
zinc finger and BTB domain containing 20
chr3_+_118430299 0.409 ENSMUST00000180774.1
 Gm26871
predicted gene, 26871
chr5_-_124187150 0.401 ENSMUST00000161938.1
 Pitpnm2
phosphatidylinositol transfer protein, membrane-associated 2
chr11_-_69602741 0.379 ENSMUST00000138694.1
 Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.3 1.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 1.1 GO:0021766 hippocampus development(GO:0021766)
0.0 1.0 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 0.8 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.7 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.7 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.7 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.2 0.6 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.4 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.4 GO:0044838 cell quiescence(GO:0044838)
0.0 0.4 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.3 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.3 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.1 0.2 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.2 GO:0042701 progesterone secretion(GO:0042701)
0.0 0.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.0 0.2 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)

Gene overrepresentation in cellular_component category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.3 GO:0045171 intercellular bridge(GO:0045171)
0.2 1.0 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.8 GO:0031430 M band(GO:0031430)
0.0 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.8 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.7 GO:0042588 zymogen granule(GO:0042588)
0.0 0.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 GO:0030507 spectrin binding(GO:0030507)
0.1 1.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.8 GO:0016208 AMP binding(GO:0016208)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.4 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.4 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.3 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)

Gene overrepresentation in C2:CP category:

Showing 1 to 1 of 1 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.5 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions