Motif ID: Atoh1_Bhlhe23
Z-value: 0.390
Transcription factors associated with Atoh1_Bhlhe23:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Atoh1 | ENSMUSG00000073043.4 | Atoh1 |
Bhlhe23 | ENSMUSG00000045493.3 | Bhlhe23 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Bhlhe23 | mm10_v2_chr2_-_180776749_180776749 | 0.60 | 8.9e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.3 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
0.2 | 0.6 | GO:0002182 | cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248) |
0.1 | 0.7 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
0.1 | 0.8 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
0.1 | 0.4 | GO:1903288 | positive regulation of potassium ion import(GO:1903288) |
0.1 | 0.7 | GO:0036371 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
0.1 | 0.2 | GO:0032240 | RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832) |
0.1 | 0.7 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
0.1 | 0.3 | GO:0030205 | dermatan sulfate metabolic process(GO:0030205) |
0.1 | 0.4 | GO:0044838 | cell quiescence(GO:0044838) |
0.0 | 0.2 | GO:0042701 | progesterone secretion(GO:0042701) |
0.0 | 0.4 | GO:0050908 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
0.0 | 0.1 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
0.0 | 1.0 | GO:0021860 | pyramidal neuron development(GO:0021860) |
0.0 | 1.4 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.0 | 0.2 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
0.0 | 0.1 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) negative regulation of lymphocyte migration(GO:2000402) |
0.0 | 0.2 | GO:2000304 | positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304) |
0.0 | 0.2 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
0.0 | 0.1 | GO:0051790 | short-chain fatty acid biosynthetic process(GO:0051790) |
0.0 | 0.2 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
0.0 | 0.1 | GO:0042822 | pyridoxal phosphate metabolic process(GO:0042822) |
0.0 | 0.3 | GO:0072112 | renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311) |
0.0 | 0.3 | GO:0033623 | regulation of integrin activation(GO:0033623) |
0.0 | 0.2 | GO:0038203 | TORC2 signaling(GO:0038203) |
0.0 | 0.1 | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) |
0.0 | 0.2 | GO:0031272 | regulation of pseudopodium assembly(GO:0031272) |
0.0 | 1.1 | GO:0021766 | hippocampus development(GO:0021766) |
0.0 | 0.1 | GO:2000671 | regulation of motor neuron apoptotic process(GO:2000671) |
0.0 | 0.2 | GO:0031507 | heterochromatin assembly(GO:0031507) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.0 | GO:0097441 | basilar dendrite(GO:0097441) |
0.1 | 0.4 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.0 | 0.7 | GO:0042588 | zymogen granule(GO:0042588) |
0.0 | 0.8 | GO:0031430 | M band(GO:0031430) |
0.0 | 0.2 | GO:0044615 | nuclear pore nuclear basket(GO:0044615) |
0.0 | 0.7 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.0 | 0.8 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 1.3 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 0.5 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
0.0 | 0.2 | GO:0005677 | chromatin silencing complex(GO:0005677) |
0.0 | 0.2 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.0 | 0.5 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 0.4 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 0.8 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
0.0 | 0.2 | GO:0031932 | TORC2 complex(GO:0031932) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.4 | GO:0098770 | FBXO family protein binding(GO:0098770) |
0.1 | 0.3 | GO:0004441 | inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) |
0.1 | 1.0 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
0.0 | 0.6 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
0.0 | 0.4 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
0.0 | 0.8 | GO:0016208 | AMP binding(GO:0016208) |
0.0 | 0.1 | GO:0004315 | 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) |
0.0 | 0.7 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 0.4 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
0.0 | 0.1 | GO:0008545 | JUN kinase kinase activity(GO:0008545) |
0.0 | 0.5 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
0.0 | 1.4 | GO:0030507 | spectrin binding(GO:0030507) |
0.0 | 0.3 | GO:0031005 | filamin binding(GO:0031005) |
0.0 | 0.2 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.0 | 0.1 | GO:0033883 | pyridoxal phosphatase activity(GO:0033883) |
0.0 | 0.3 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
0.0 | 0.7 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
0.0 | 0.1 | GO:0045322 | unmethylated CpG binding(GO:0045322) |
0.0 | 0.2 | GO:0000900 | translation repressor activity, nucleic acid binding(GO:0000900) |
0.0 | 0.1 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.5 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.7 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
0.0 | 0.5 | REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS | Genes involved in Voltage gated Potassium channels |
0.0 | 0.4 | REACTOME_BASIGIN_INTERACTIONS | Genes involved in Basigin interactions |
0.0 | 0.3 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |