Motif ID: Barhl1

Z-value: 0.475


Transcription factors associated with Barhl1:

Gene SymbolEntrez IDGene Name
Barhl1 ENSMUSG00000026805.8 Barhl1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Barhl1mm10_v2_chr2_-_28916412_28916440-0.175.1e-01Click!


Activity profile for motif Barhl1.

activity profile for motif Barhl1


Sorted Z-values histogram for motif Barhl1

Sorted Z-values for motif Barhl1



Network of associatons between targets according to the STRING database.



First level regulatory network of Barhl1

PNG image of the network

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Top targets:


Showing 1 to 20 of 54 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_92292380 1.248 ENSMUST00000047383.3
Kcne2
potassium voltage-gated channel, Isk-related subfamily, gene 2
chr2_-_151632471 0.552 ENSMUST00000137936.1
ENSMUST00000146172.1
ENSMUST00000094456.3
ENSMUST00000148755.1
ENSMUST00000109875.1
ENSMUST00000028951.7
ENSMUST00000109877.3
Snph






syntaphilin






chr1_-_75278345 0.529 ENSMUST00000039534.4
Resp18
regulated endocrine-specific protein 18
chr15_-_43869993 0.436 ENSMUST00000067469.4
Tmem74
transmembrane protein 74
chr2_-_80128834 0.383 ENSMUST00000102654.4
ENSMUST00000102655.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr17_-_78418083 0.347 ENSMUST00000070039.7
ENSMUST00000112487.1
Fez2

fasciculation and elongation protein zeta 2 (zygin II)

chr3_-_146770603 0.317 ENSMUST00000106138.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr3_-_146770218 0.309 ENSMUST00000106137.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr2_-_45110336 0.309 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr15_-_53902472 0.291 ENSMUST00000078673.6
Samd12
sterile alpha motif domain containing 12
chr5_-_24581879 0.290 ENSMUST00000088299.4
Gm10221
predicted gene 10221
chr3_+_75557530 0.259 ENSMUST00000161776.1
ENSMUST00000029423.8
Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

chr6_+_72097561 0.251 ENSMUST00000069994.4
ENSMUST00000114112.1
St3gal5

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

chr7_+_45896941 0.238 ENSMUST00000069772.7
ENSMUST00000107716.1
Tmem143

transmembrane protein 143

chr11_+_22971991 0.236 ENSMUST00000049506.5
Zrsr1
zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1
chr16_+_10827921 0.228 ENSMUST00000181732.1
Gm26822
predicted gene, 26822
chr7_+_97842917 0.215 ENSMUST00000033040.5
Pak1
p21 protein (Cdc42/Rac)-activated kinase 1
chr18_+_37355271 0.213 ENSMUST00000051163.1
Pcdhb8
protocadherin beta 8
chr5_-_62765618 0.207 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_-_59426279 0.205 ENSMUST00000051065.4
Gprin3
GPRIN family member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.2 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.1 0.6 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.5 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.3 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.2 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.2 GO:0051030 snRNA transport(GO:0051030)
0.0 0.2 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.0 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)

Gene overrepresentation in cellular_component category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.5 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.3 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0071437 invadopodium(GO:0071437)
0.0 0.2 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)

Gene overrepresentation in molecular_function category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.2 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 0.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.4 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)

Gene overrepresentation in C2:CP category:

Showing 1 to 2 of 2 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.2 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.4 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.0 0.2 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway