ISMARA results: Bbx

Motif ID: Bbx

Z-value: 0.343

Transcription factors associated with Bbx:

Gene Symbol	Entrez ID	Gene Name
Bbx	ENSMUSG00000022641.9	Bbx

Activity-expression correlation:

Gene Symbol	Promoter	Pearson corr. coef.	P-value	Plot
Bbx	mm10_v2_chr16_-_50432340_50432409	-0.25	3.2e-01	Click!

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_+_21111452	1.788	ENSMUST00000075132.6	Cdh12	cadherin 12
chr5_-_146585239	1.393	ENSMUST00000036211.6	Gpr12	G-protein coupled receptor 12
chr13_-_52530827	0.884	ENSMUST00000057442.6	Diras2	DIRAS family, GTP-binding RAS-like 2
chr18_+_37421418	0.751	ENSMUST00000053073.4	Pcdhb11	protocadherin beta 11
chr13_+_49608030	0.659	ENSMUST00000021822.5	Ogn	osteoglycin
chr10_+_86021961	0.655	ENSMUST00000130320.1	Fbxo7	F-box protein 7
chrX_+_159708593	0.490	ENSMUST00000080394.6	Sh3kbp1	SH3-domain kinase binding protein 1
chr2_+_136892168	0.425	ENSMUST00000099311.2	Slx4ip	SLX4 interacting protein
chrX_+_140367494	0.401	ENSMUST00000141660.1	Frmpd3	FERM and PDZ domain containing 3
chr1_+_180111339	0.378	ENSMUST00000145181.1	Cdc42bpa	CDC42 binding protein kinase alpha
chr10_+_84622365	0.264	ENSMUST00000077175.5	Polr3b	polymerase (RNA) III (DNA directed) polypeptide B
chr8_-_41054771	0.203	ENSMUST00000093534.4	Mtus1	mitochondrial tumor suppressor 1
chr16_+_20693263	0.190	ENSMUST00000149543.1 ENSMUST00000118919.1	Fam131a	family with sequence similarity 131, member A
chrX_-_107816238	0.178	ENSMUST00000120722.1	2610002M06Rik	RIKEN cDNA 2610002M06 gene
chr11_+_105146893	0.169	ENSMUST00000100338.1	Gm10842	predicted gene 10842
chrX_-_150814265	0.133	ENSMUST00000026302.6 ENSMUST00000129768.1 ENSMUST00000112699.2	Maged2	melanoma antigen, family D, 2
chr10_-_86022325	0.092	ENSMUST00000181665.1	A230060F14Rik	RIKEN cDNA A230060F14 gene
chr12_-_86079019	0.079	ENSMUST00000003687.6	Tgfb3	transforming growth factor, beta 3
chr1_-_163725123	0.043	ENSMUST00000159679.1	Mettl11b	methyltransferase like 11B
chr7_-_127708738	0.036	ENSMUST00000106282.1	Bcl7c	B cell CLL/lymphoma 7C

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:1903207	neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.0	0.1	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.1	GO:0070294	renal sodium ion absorption(GO:0070294)
0.0	1.8	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.4	GO:0007097	nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:1990037	Lewy body core(GO:1990037)
0.0	0.3	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.1	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	0.3	GO:0001056	RNA polymerase III activity(GO:0001056)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.7	NABA_PROTEOGLYCANS	Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME_KERATAN_SULFATE_DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	1.8	REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.3	REACTOME_RNA_POL_III_CHAIN_ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.5	REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers