Motif ID: Bcl6b
Z-value: 0.595
Transcription factors associated with Bcl6b:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Bcl6b | ENSMUSG00000000317.5 | Bcl6b |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Bcl6b | mm10_v2_chr11_-_70229677_70229761 | 0.65 | 3.8e-03 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 5.2 | GO:0014012 | peripheral nervous system axon regeneration(GO:0014012) |
| 1.1 | 3.3 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 0.6 | 2.8 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.5 | 2.6 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.3 | 2.4 | GO:0061368 | maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368) |
| 0.2 | 1.0 | GO:1902037 | negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
| 0.2 | 0.6 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.2 | 1.2 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
| 0.2 | 1.2 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.2 | 1.1 | GO:0060371 | regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) |
| 0.1 | 0.4 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
| 0.1 | 0.2 | GO:0001951 | intestinal D-glucose absorption(GO:0001951) terminal web assembly(GO:1902896) |
| 0.1 | 0.7 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.1 | 0.4 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
| 0.1 | 0.3 | GO:0051661 | maintenance of centrosome location(GO:0051661) |
| 0.1 | 0.3 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.0 | 1.2 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.0 | 1.2 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
| 0.0 | 1.4 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 0.7 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 0.0 | 0.9 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
| 0.0 | 0.3 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.0 | 0.9 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.2 | GO:0098835 | presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) |
| 0.3 | 5.2 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.3 | 3.8 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.1 | 3.3 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 0.3 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.0 | 0.2 | GO:1990357 | terminal web(GO:1990357) |
| 0.0 | 0.4 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.0 | 1.0 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 5.2 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.4 | 3.3 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.2 | 1.1 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.1 | 1.2 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.1 | 2.8 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) |
| 0.1 | 0.6 | GO:0015265 | urea channel activity(GO:0015265) |
| 0.1 | 0.4 | GO:0004528 | phosphodiesterase I activity(GO:0004528) |
| 0.1 | 2.4 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 0.7 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.0 | 0.1 | GO:1990450 | linear polyubiquitin binding(GO:1990450) |
| 0.0 | 0.7 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 1.0 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.0 | 1.2 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.2 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.1 | 2.4 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
| 0.0 | 0.3 | ST_INTERFERON_GAMMA_PATHWAY | Interferon gamma pathway. |
| 0.0 | 0.7 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.7 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.1 | 3.3 | REACTOME_SIGNALING_BY_ROBO_RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.1 | 5.0 | REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 0.6 | REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.0 | 2.4 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 1.1 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.1 | REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
