Motif ID: Bcl6b

Z-value: 0.595


Transcription factors associated with Bcl6b:

Gene SymbolEntrez IDGene Name
Bcl6b ENSMUSG00000000317.5 Bcl6b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bcl6bmm10_v2_chr11_-_70229677_702297610.653.8e-03Click!


Activity profile for motif Bcl6b.

activity profile for motif Bcl6b


Sorted Z-values histogram for motif Bcl6b

Sorted Z-values for motif Bcl6b



Network of associatons between targets according to the STRING database.



First level regulatory network of Bcl6b

PNG image of the network

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Top targets:


Showing 1 to 20 of 68 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_64046925 5.183 ENSMUST00000107377.3
Tnc
tenascin C
chr19_-_5797410 2.618 ENSMUST00000173314.1
Malat1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr16_-_74411776 1.814 ENSMUST00000116586.2
Robo2
roundabout homolog 2 (Drosophila)
chrX_+_151344171 1.680 ENSMUST00000073364.5
Fam120c
family with sequence similarity 120, member C
chr16_-_74411292 1.509 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr10_+_81633694 1.430 ENSMUST00000140345.1
ENSMUST00000126323.1
Ankrd24

ankyrin repeat domain 24

chr2_-_65567465 1.392 ENSMUST00000066432.5
Scn3a
sodium channel, voltage-gated, type III, alpha
chr9_-_112232449 1.378 ENSMUST00000035085.5
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr2_-_65567505 1.375 ENSMUST00000100069.2
Scn3a
sodium channel, voltage-gated, type III, alpha
chr12_-_40134175 1.221 ENSMUST00000078481.7
ENSMUST00000002640.5
Scin

scinderin

chr1_-_173942445 1.177 ENSMUST00000042228.8
ENSMUST00000081216.5
ENSMUST00000129829.1
ENSMUST00000123708.1
ENSMUST00000111210.2
Ifi203



Mndal
interferon activated gene 203



myeloid nuclear differentiation antigen like
chr10_+_57794335 1.177 ENSMUST00000151623.1
ENSMUST00000020022.7
Smpdl3a

sphingomyelin phosphodiesterase, acid-like 3A

chr13_-_98815408 1.162 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
Fcho2



FCH domain only 2



chr8_+_13907748 1.087 ENSMUST00000043520.3
Fbxo25
F-box protein 25
chr9_+_40269430 1.051 ENSMUST00000171835.2
Scn3b
sodium channel, voltage-gated, type III, beta
chr16_-_34263179 0.963 ENSMUST00000114949.1
ENSMUST00000114954.1
Kalrn

kalirin, RhoGEF kinase

chr5_-_123140135 0.945 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr3_+_55242526 0.870 ENSMUST00000054237.7
ENSMUST00000167204.1
Dclk1

doublecortin-like kinase 1

chr9_-_90255927 0.851 ENSMUST00000144646.1
Tbc1d2b
TBC1 domain family, member 2B
chr16_-_34262830 0.845 ENSMUST00000114947.1
Kalrn
kalirin, RhoGEF kinase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 5.2 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
1.1 3.3 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.6 2.8 GO:0046684 response to pyrethroid(GO:0046684)
0.5 2.6 GO:0035063 nuclear speck organization(GO:0035063)
0.3 2.4 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 1.4 GO:0034605 cellular response to heat(GO:0034605)
0.2 1.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.2 1.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 1.2 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.2 1.1 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.2 1.0 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.9 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.9 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 0.7 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.7 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 0.6 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.4 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 5.2 GO:0005614 interstitial matrix(GO:0005614)
0.3 3.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 3.3 GO:0030673 axolemma(GO:0030673)
0.4 1.2 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.3 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:1990357 terminal web(GO:1990357)

Gene overrepresentation in molecular_function category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.9 5.2 GO:0045545 syndecan binding(GO:0045545)
0.4 3.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 2.8 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.1 2.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.2 1.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 1.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.7 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.6 GO:0015265 urea channel activity(GO:0015265)
0.1 0.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)

Gene overrepresentation in C2:CP category:

Showing 1 to 4 of 4 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.2 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.7 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.3 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.0 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 3.3 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 2.4 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 1.1 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 0.7 REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.1 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1