Motif ID: Bptf

Z-value: 0.919


Transcription factors associated with Bptf:

Gene SymbolEntrez IDGene Name
Bptf ENSMUSG00000040481.10 Bptf

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bptfmm10_v2_chr11_-_107131922_1071319540.682.0e-03Click!


Activity profile for motif Bptf.

activity profile for motif Bptf


Sorted Z-values histogram for motif Bptf

Sorted Z-values for motif Bptf



Network of associatons between targets according to the STRING database.



First level regulatory network of Bptf

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_116968969 2.640 ENSMUST00000143611.1
ENSMUST00000040097.7
 Palmd

palmdelphin

chr4_+_144892813 2.337 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr8_-_84773381 2.186 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr15_+_77084367 1.965 ENSMUST00000181870.1
 1700109K24Rik
RIKEN cDNA 1700109K24 gene
chr16_+_43510267 1.928 ENSMUST00000114695.2
 Zbtb20
zinc finger and BTB domain containing 20
chr17_+_35076902 1.807 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
 Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr1_+_20917856 1.659 ENSMUST00000167119.1
 Paqr8
progestin and adipoQ receptor family member VIII
chr12_-_90738438 1.650 ENSMUST00000082432.3
 Dio2
deiodinase, iodothyronine, type II
chr8_-_11008458 1.610 ENSMUST00000040514.6
 Irs2
insulin receptor substrate 2
chr1_+_34005872 1.368 ENSMUST00000182296.1
 Dst
dystonin
chr7_+_131410601 1.365 ENSMUST00000015829.7
ENSMUST00000117518.1
 Acadsb

acyl-Coenzyme A dehydrogenase, short/branched chain

chr7_-_19166119 1.360 ENSMUST00000094790.3
 Gipr
gastric inhibitory polypeptide receptor
chr16_+_37916440 1.352 ENSMUST00000061274.7
 Gpr156
G protein-coupled receptor 156
chr16_+_45093611 1.338 ENSMUST00000099498.2
 Ccdc80
coiled-coil domain containing 80
chr13_+_83573577 1.295 ENSMUST00000185052.1
 Mef2c
myocyte enhancer factor 2C
chr4_+_144893077 1.289 ENSMUST00000154208.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr15_-_99820072 1.271 ENSMUST00000109024.2
 Lima1
LIM domain and actin binding 1
chr1_-_56978534 1.255 ENSMUST00000177282.1
 Satb2
special AT-rich sequence binding protein 2
chr4_-_53159885 1.200 ENSMUST00000030010.3
 Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr17_+_35077080 1.188 ENSMUST00000172959.1
 Ly6g6e
lymphocyte antigen 6 complex, locus G6E

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 288 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.9 GO:0008360 regulation of cell shape(GO:0008360)
0.4 4.7 GO:0042572 retinol metabolic process(GO:0042572)
0.1 4.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 4.4 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.0 3.9 GO:0008643 carbohydrate transport(GO:0008643)
0.0 2.9 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 2.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 2.4 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.4 2.1 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 1.9 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.2 1.8 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 1.8 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.3 1.6 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.2 1.6 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 1.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 1.5 GO:0034605 cellular response to heat(GO:0034605)
0.0 1.5 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 1.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.4 1.3 GO:0007521 muscle cell fate determination(GO:0007521) cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 1.3 GO:0007212 dopamine receptor signaling pathway(GO:0007212)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 105 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.9 GO:0043197 dendritic spine(GO:0043197)
0.0 3.8 GO:0000139 Golgi membrane(GO:0000139)
0.2 3.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 2.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.4 GO:0030139 endocytic vesicle(GO:0030139)
0.0 2.1 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.9 GO:0000800 lateral element(GO:0000800)
0.0 1.9 GO:0014704 intercalated disc(GO:0014704)
0.1 1.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.8 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.8 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.6 GO:0030016 myofibril(GO:0030016)
0.3 1.4 GO:0031673 H zone(GO:0031673)
0.0 1.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 1.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.4 1.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 1.1 GO:0005776 autophagosome(GO:0005776)
0.0 1.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.3 1.0 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.1 1.0 GO:0090533 cation-transporting ATPase complex(GO:0090533)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 198 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 4.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.0 3.0 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 2.7 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 2.7 GO:0030507 spectrin binding(GO:0030507)
0.0 2.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 2.5 GO:0017124 SH3 domain binding(GO:0017124)
0.1 2.4 GO:0005158 insulin receptor binding(GO:0005158)
0.1 2.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 2.2 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 2.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 1.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.6 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.2 1.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 1.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.4 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 1.3 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.3 GO:0031402 sodium ion binding(GO:0031402)
0.0 1.3 GO:0005496 steroid binding(GO:0005496)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.7 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 3.1 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 2.5 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.9 PID_IGF1_PATHWAY IGF1 pathway
0.0 1.4 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 1.3 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 1.1 PID_ERBB1_INTERNALIZATION_PATHWAY Internalization of ErbB1
0.0 1.1 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 1.0 PID_CONE_PATHWAY Visual signal transduction: Cones
0.0 0.9 SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES Genes related to the insulin receptor pathway
0.0 0.9 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 0.9 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.8 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.7 PID_THROMBIN_PAR1_PATHWAY PAR1-mediated thrombin signaling events
0.0 0.6 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.5 PID_HNF3A_PATHWAY FOXA1 transcription factor network
0.0 0.5 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.0 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.1 1.8 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.1 1.8 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.6 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.1 1.5 REACTOME_AMINE_DERIVED_HORMONES Genes involved in Amine-derived hormones
0.1 1.4 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.4 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 1.4 REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 1.3 REACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.3 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 1.3 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.2 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.2 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.1 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 1.0 REACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.9 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.8 REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.8 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling