Motif ID: Cdx2

Z-value: 0.491


Transcription factors associated with Cdx2:

Gene SymbolEntrez IDGene Name
Cdx2 ENSMUSG00000029646.3 Cdx2



Activity profile for motif Cdx2.

activity profile for motif Cdx2


Sorted Z-values histogram for motif Cdx2

Sorted Z-values for motif Cdx2



Network of associatons between targets according to the STRING database.



First level regulatory network of Cdx2

PNG image of the network

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Top targets:


Showing 1 to 20 of 52 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_64046925 1.622 ENSMUST00000107377.3
 Tnc
tenascin C
chr2_+_31759993 1.027 ENSMUST00000124089.1
 Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr2_-_59948155 0.838 ENSMUST00000153136.1
 Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr2_+_4300462 0.813 ENSMUST00000175669.1
 Frmd4a
FERM domain containing 4A
chr14_-_54686060 0.797 ENSMUST00000125265.1
 Acin1
apoptotic chromatin condensation inducer 1
chr13_+_23934434 0.758 ENSMUST00000072391.1
 Hist1h2aa
histone cluster 1, H2aa
chr18_+_65582239 0.717 ENSMUST00000182684.1
 Zfp532
zinc finger protein 532
chr12_-_102878406 0.716 ENSMUST00000045652.6
 Btbd7
BTB (POZ) domain containing 7
chr3_+_118433797 0.634 ENSMUST00000180593.1
ENSMUST00000181926.1
ENSMUST00000181060.1
ENSMUST00000181310.1
 Gm26871



predicted gene, 26871



chr3_+_88965812 0.559 ENSMUST00000090933.4
 Ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr5_+_121777929 0.521 ENSMUST00000160821.1
 Atxn2
ataxin 2
chr4_+_144893127 0.516 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr2_+_31759932 0.458 ENSMUST00000028190.6
 Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr18_+_65582281 0.435 ENSMUST00000183319.1
 Zfp532
zinc finger protein 532
chr3_+_40540751 0.435 ENSMUST00000091186.3
 Intu
inturned planar cell polarity effector homolog (Drosophila)
chr10_+_69787431 0.387 ENSMUST00000183240.1
 Ank3
ankyrin 3, epithelial
chr1_-_186705980 0.367 ENSMUST00000045288.8
 Tgfb2
transforming growth factor, beta 2
chr18_+_37513652 0.325 ENSMUST00000061405.4
 Pcdhb21
protocadherin beta 21
chr3_-_142169196 0.312 ENSMUST00000098568.1
 Bmpr1b
bone morphogenetic protein receptor, type 1B
chr18_+_65582390 0.311 ENSMUST00000169679.1
ENSMUST00000183326.1
 Zfp532

zinc finger protein 532


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 1.6 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.5 1.5 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.1 0.8 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.7 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.1 0.6 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.0 0.5 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.5 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.1 0.4 GO:1902256 endocardial cushion fusion(GO:0003274) apoptotic process involved in outflow tract morphogenesis(GO:0003275) atrial septum primum morphogenesis(GO:0003289) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.4 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.3 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.3 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.0 0.3 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.3 GO:0035994 response to muscle stretch(GO:0035994)
0.0 0.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.2 GO:0001692 histamine metabolic process(GO:0001692) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.0 0.1 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)

Gene overrepresentation in cellular_component category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.8 GO:0061574 ASAP complex(GO:0061574)
0.0 0.7 GO:0043194 axon initial segment(GO:0043194)
0.0 0.3 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0042581 specific granule(GO:0042581)

Gene overrepresentation in molecular_function category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.6 GO:0045545 syndecan binding(GO:0045545)
0.1 1.5 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.5 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)

Gene overrepresentation in C2:CP category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.5 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.6 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.5 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME_SIGNALING_BY_BMP Genes involved in Signaling by BMP