Motif ID: Cebpa_Cebpg

Z-value: 0.545

Transcription factors associated with Cebpa_Cebpg:

Gene SymbolEntrez IDGene Name
Cebpa ENSMUSG00000034957.9 Cebpa
Cebpg ENSMUSG00000056216.8 Cebpg

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cebpamm10_v2_chr7_+_35119285_35119301-0.233.5e-01Click!
Cebpgmm10_v2_chr7_-_35056467_35056556-0.204.3e-01Click!


Activity profile for motif Cebpa_Cebpg.

activity profile for motif Cebpa_Cebpg


Sorted Z-values histogram for motif Cebpa_Cebpg

Sorted Z-values for motif Cebpa_Cebpg



Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpa_Cebpg

PNG image of the network

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Top targets:


Showing 1 to 20 of 154 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_121495678 1.827 ENSMUST00000035120.4
 Cck
cholecystokinin
chr7_-_103813913 1.699 ENSMUST00000098192.3
 Hbb-bt
hemoglobin, beta adult t chain
chr1_-_22315792 1.315 ENSMUST00000164877.1
 Rims1
regulating synaptic membrane exocytosis 1
chr19_-_57239310 1.168 ENSMUST00000111559.1
 Ablim1
actin-binding LIM protein 1
chr9_+_37367354 1.096 ENSMUST00000051839.7
 Hepacam
hepatocyte cell adhesion molecule
chr13_-_117025505 1.007 ENSMUST00000022239.6
 Parp8
poly (ADP-ribose) polymerase family, member 8
chrX_-_162565514 0.994 ENSMUST00000154424.1
 Reps2
RALBP1 associated Eps domain containing protein 2
chr1_-_38821215 0.982 ENSMUST00000039612.4
 Lonrf2
LON peptidase N-terminal domain and ring finger 2
chr6_+_17463749 0.982 ENSMUST00000115443.1
 Met
met proto-oncogene
chr2_-_65567465 0.840 ENSMUST00000066432.5
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_-_65567505 0.771 ENSMUST00000100069.2
 Scn3a
sodium channel, voltage-gated, type III, alpha
chr2_-_45117349 0.759 ENSMUST00000176438.2
 Zeb2
zinc finger E-box binding homeobox 2
chr9_-_89092835 0.707 ENSMUST00000167113.1
 Trim43b
tripartite motif-containing 43B
chr2_-_52676571 0.672 ENSMUST00000178799.1
 Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
chr3_+_66219909 0.646 ENSMUST00000029421.5
 Ptx3
pentraxin related gene
chr12_+_74297474 0.637 ENSMUST00000072100.3
 Dbpht2
DNA binding protein with his-thr domain
chr15_-_65014904 0.629 ENSMUST00000110100.2
 Gm21961
predicted gene, 21961
chr13_+_109903089 0.608 ENSMUST00000120664.1
 Pde4d
phosphodiesterase 4D, cAMP specific
chr14_+_65971049 0.572 ENSMUST00000128539.1
 Clu
clusterin
chr16_+_42907563 0.562 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.8 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.2 1.8 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.3 1.6 GO:0046684 response to pyrethroid(GO:0046684)
0.1 1.4 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.3 1.3 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 1.0 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.2 0.8 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.8 GO:1903056 positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 0.7 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.7 GO:0019227 neuronal action potential propagation(GO:0019227) detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) action potential propagation(GO:0098870)
0.1 0.6 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.6 GO:1901898 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.6 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 0.5 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.5 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 0.5 GO:0032264 IMP salvage(GO:0032264)
0.1 0.5 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.5 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.1 0.4 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.4 GO:0090024 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.8 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 1.8 GO:0043203 axon hillock(GO:0043203)
0.4 1.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 1.5 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.3 1.3 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0044754 autolysosome(GO:0044754)
0.0 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.8 GO:0051787 misfolded protein binding(GO:0051787)
0.4 1.7 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.1 1.6 GO:0031402 sodium ion binding(GO:0031402)
0.0 1.4 GO:0030507 spectrin binding(GO:0030507)
0.2 1.0 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.8 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 0.7 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.6 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.5 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 0.4 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)

Gene overrepresentation in C2:CP category:

Showing 1 to 3 of 3 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 PID_MYC_REPRESS_PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.0 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.8 REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.4 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.3 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 1.2 REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2_ Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.0 REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.7 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.4 REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME_GABA_A_RECEPTOR_ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels