Motif ID: Cebpb

Z-value: 0.570


Transcription factors associated with Cebpb:

Gene SymbolEntrez IDGene Name
Cebpb ENSMUSG00000056501.3 Cebpb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cebpbmm10_v2_chr2_+_167688915_1676889730.331.8e-01Click!


Activity profile for motif Cebpb.

activity profile for motif Cebpb


Sorted Z-values histogram for motif Cebpb

Sorted Z-values for motif Cebpb



Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpb

PNG image of the network

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Top targets:


Showing 1 to 20 of 170 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_12684991 0.760 ENSMUST00000172743.1
ENSMUST00000167771.1
 Vmn2r55

vomeronasal 2, receptor 55

chr12_-_56535047 0.658 ENSMUST00000178477.2
 Nkx2-1
NK2 homeobox 1
chr13_-_49309217 0.651 ENSMUST00000110087.2
 Fgd3
FYVE, RhoGEF and PH domain containing 3
chr5_+_75152274 0.609 ENSMUST00000000476.8
 Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr12_+_88953399 0.590 ENSMUST00000057634.7
 Nrxn3
neurexin III
chr10_+_93488766 0.555 ENSMUST00000129421.1
 Hal
histidine ammonia lyase
chr15_-_65014904 0.445 ENSMUST00000110100.2
 Gm21961
predicted gene, 21961
chr6_-_23248264 0.410 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr18_-_38601268 0.338 ENSMUST00000025295.6
 Spry4
sprouty homolog 4 (Drosophila)
chr4_+_136172367 0.330 ENSMUST00000061721.5
 E2f2
E2F transcription factor 2
chr13_+_24614608 0.310 ENSMUST00000091694.3
 Fam65b
family with sequence similarity 65, member B
chr9_-_89092835 0.297 ENSMUST00000167113.1
 Trim43b
tripartite motif-containing 43B
chr1_-_71653162 0.284 ENSMUST00000055226.6
 Fn1
fibronectin 1
chr2_-_160872829 0.283 ENSMUST00000176141.1
 Zhx3
zinc fingers and homeoboxes 3
chr6_+_54326955 0.280 ENSMUST00000059138.4
 Prr15
proline rich 15
chr11_-_120630126 0.276 ENSMUST00000106180.1
 Mafg
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr4_+_133176336 0.272 ENSMUST00000105912.1
 Wasf2
WAS protein family, member 2
chr18_+_4994600 0.257 ENSMUST00000140448.1
 Svil
supervillin
chr4_-_43558386 0.256 ENSMUST00000130353.1
 Tln1
talin 1
chr8_+_75093591 0.254 ENSMUST00000005548.6
 Hmox1
heme oxygenase (decycling) 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 GO:0046847 filopodium assembly(GO:0046847)
0.2 0.7 GO:0021759 globus pallidus development(GO:0021759)
0.2 0.6 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.1 0.6 GO:0006547 histidine metabolic process(GO:0006547) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.5 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.3 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044)
0.1 0.3 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.3 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.3 GO:1904706 heme oxidation(GO:0006788) negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.2 GO:0071726 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.0 0.2 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.2 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 0.2 GO:0042581 specific granule(GO:0042581)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.0 GO:0070820 tertiary granule(GO:0070820)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 0.6 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 0.6 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.3 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.3 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.3 GO:0045340 mercury ion binding(GO:0045340)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.2 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.2 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)

Gene overrepresentation in C2:CP category:

Showing 1 to 7 of 7 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.8 PID_INTEGRIN_A4B1_PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.7 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.3 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.3 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.2 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 0.1 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 9 of 9 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.3 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.3 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.1 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.1 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism