Motif ID: Cebpd

Z-value: 0.490


Transcription factors associated with Cebpd:

Gene SymbolEntrez IDGene Name
Cebpd ENSMUSG00000071637.4 Cebpd



Activity profile for motif Cebpd.

activity profile for motif Cebpd


Sorted Z-values histogram for motif Cebpd

Sorted Z-values for motif Cebpd



Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpd

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_71653162 1.124 ENSMUST00000055226.6
Fn1
fibronectin 1
chr7_-_127273919 1.107 ENSMUST00000082428.3
Sephs2
selenophosphate synthetase 2
chr18_-_52529847 0.884 ENSMUST00000171470.1
Lox
lysyl oxidase
chr8_-_33929798 0.873 ENSMUST00000033995.7
ENSMUST00000033994.8
ENSMUST00000053251.5
Rbpms


RNA binding protein gene with multiple splicing


chr2_-_57113053 0.863 ENSMUST00000112627.1
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr10_-_6980376 0.863 ENSMUST00000105617.1
Ipcef1
interaction protein for cytohesin exchange factors 1
chr2_+_25180737 0.856 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr18_-_52529692 0.793 ENSMUST00000025409.7
Lox
lysyl oxidase
chr4_-_108833544 0.688 ENSMUST00000102740.1
ENSMUST00000102741.1
Btf3l4

basic transcription factor 3-like 4

chr4_-_108833608 0.650 ENSMUST00000102742.4
Btf3l4
basic transcription factor 3-like 4
chr4_+_55350043 0.631 ENSMUST00000030134.8
Rad23b
RAD23b homolog (S. cerevisiae)
chr5_+_63812447 0.596 ENSMUST00000081747.3
0610040J01Rik
RIKEN cDNA 0610040J01 gene
chr17_-_56121946 0.572 ENSMUST00000041357.7
Lrg1
leucine-rich alpha-2-glycoprotein 1
chr17_+_86963077 0.560 ENSMUST00000024956.8
Rhoq
ras homolog gene family, member Q
chr2_+_155751117 0.544 ENSMUST00000029140.5
ENSMUST00000132608.1
Procr

protein C receptor, endothelial

chr12_+_37241633 0.431 ENSMUST00000049874.7
Agmo
alkylglycerol monooxygenase
chrX_-_134600976 0.428 ENSMUST00000033621.6
Gla
galactosidase, alpha
chrX_+_134601179 0.419 ENSMUST00000074950.4
ENSMUST00000113203.1
ENSMUST00000113202.1
Hnrnph2


heterogeneous nuclear ribonucleoprotein H2


chr4_-_130359915 0.415 ENSMUST00000134159.2
Zcchc17
zinc finger, CCHC domain containing 17
chr1_-_162898665 0.410 ENSMUST00000111510.1
ENSMUST00000045902.6
Fmo2

flavin containing monooxygenase 2

chr11_-_48826500 0.405 ENSMUST00000161192.2
Gm12184
predicted gene 12184
chr11_-_48826655 0.381 ENSMUST00000104959.1
Gm12184
predicted gene 12184
chr11_-_87086752 0.379 ENSMUST00000020801.7
Smg8
smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr12_+_86421628 0.369 ENSMUST00000110203.1
ENSMUST00000110204.2
Esrrb

estrogen related receptor, beta

chr11_-_75422586 0.350 ENSMUST00000138661.1
ENSMUST00000000769.7
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr5_-_145140238 0.343 ENSMUST00000031627.8
Pdap1
PDGFA associated protein 1
chr13_+_63015167 0.342 ENSMUST00000021911.8
2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr7_-_45830776 0.335 ENSMUST00000107723.2
ENSMUST00000131384.1
Grwd1

glutamate-rich WD repeat containing 1

chr5_+_145140362 0.330 ENSMUST00000162594.1
ENSMUST00000162308.1
ENSMUST00000159018.1
ENSMUST00000160075.1
Bud31



BUD31 homolog (yeast)



chrX_+_134601271 0.318 ENSMUST00000050331.6
ENSMUST00000059297.5
Hnrnph2

heterogeneous nuclear ribonucleoprotein H2

chr5_+_115279666 0.283 ENSMUST00000040421.4
Coq5
coenzyme Q5 homolog, methyltransferase (yeast)
chr14_+_67716095 0.281 ENSMUST00000078053.6
ENSMUST00000145542.1
ENSMUST00000125212.1
Kctd9


potassium channel tetramerisation domain containing 9


chr2_-_129371131 0.279 ENSMUST00000028881.7
Il1b
interleukin 1 beta
chr17_+_48346401 0.278 ENSMUST00000024791.8
Trem2
triggering receptor expressed on myeloid cells 2
chrX_+_7763943 0.267 ENSMUST00000144900.1
ENSMUST00000115677.1
ENSMUST00000101695.2
ENSMUST00000115678.2
Tfe3



transcription factor E3



chr1_-_140183404 0.249 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh

complement component factor h

chr8_-_46211284 0.243 ENSMUST00000034049.4
Slc25a4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr11_+_6415443 0.236 ENSMUST00000132846.1
Ppia
peptidylprolyl isomerase A
chr1_-_140183283 0.224 ENSMUST00000111977.1
Cfh
complement component factor h
chr9_-_103230262 0.219 ENSMUST00000165296.1
ENSMUST00000112645.1
ENSMUST00000166836.1
Trf

Gm20425
transferrin

predicted gene 20425
chr17_+_48346465 0.218 ENSMUST00000113237.3
Trem2
triggering receptor expressed on myeloid cells 2
chr3_+_19957037 0.198 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp


ceruloplasmin


chr7_+_24507006 0.183 ENSMUST00000176880.1
Zfp428
zinc finger protein 428
chr18_+_20944607 0.182 ENSMUST00000050004.1
Rnf125
ring finger protein 125
chr17_+_86963279 0.176 ENSMUST00000139344.1
Rhoq
ras homolog gene family, member Q
chr11_-_75422524 0.173 ENSMUST00000125982.1
ENSMUST00000137103.1
Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chrX_+_159303266 0.171 ENSMUST00000112491.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr11_-_78080360 0.134 ENSMUST00000021183.3
Eral1
Era (G-protein)-like 1 (E. coli)
chr11_+_62077018 0.130 ENSMUST00000092415.5
Specc1
sperm antigen with calponin homology and coiled-coil domains 1
chr12_-_84194007 0.126 ENSMUST00000110294.1
Elmsan1
ELM2 and Myb/SANT-like domain containing 1
chr12_+_24572276 0.123 ENSMUST00000085553.5
Grhl1
grainyhead-like 1 (Drosophila)
chr2_-_3512746 0.121 ENSMUST00000027961.5
ENSMUST00000056700.7
Hspa14
Hspa14
heat shock protein 14
heat shock protein 14
chr4_+_152039315 0.111 ENSMUST00000084116.6
ENSMUST00000105663.1
ENSMUST00000103197.3
Nol9


nucleolar protein 9


chr7_+_30751471 0.099 ENSMUST00000182229.1
ENSMUST00000182227.1
ENSMUST00000080518.6
ENSMUST00000182721.1
Sbsn



suprabasin



chr19_-_8819314 0.054 ENSMUST00000096751.4
Ttc9c
tetratricopeptide repeat domain 9C

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) transforming growth factor-beta secretion(GO:0038044)
0.3 1.1 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.2 0.9 GO:0051866 general adaptation syndrome(GO:0051866)
0.2 0.6 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.2 1.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 0.5 GO:0002586 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
0.1 0.4 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.3 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.1 0.4 GO:0090282 positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931) positive regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0090282)
0.1 0.2 GO:0015866 ADP transport(GO:0015866)
0.1 0.5 GO:0045919 complement activation, alternative pathway(GO:0006957) positive regulation of cytolysis(GO:0045919)
0.1 0.9 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.5 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.4 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.9 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.0 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.7 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:0002934 desmosome organization(GO:0002934)
0.0 0.6 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:0098707 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.5 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.2 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.3 GO:0043171 peptide catabolic process(GO:0043171)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.6 GO:0071942 XPC complex(GO:0071942)
0.0 0.5 GO:0043203 axon hillock(GO:0043203)
0.0 0.9 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 1.7 GO:0005581 collagen trimer(GO:0005581)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 1.1 GO:0045340 mercury ion binding(GO:0045340)
0.2 0.9 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.5 GO:0070891 peptidoglycan binding(GO:0042834) lipoteichoic acid binding(GO:0070891)
0.1 0.5 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.1 0.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.7 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.9 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.1 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 0.8 REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.6 REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER Genes involved in Formation of incision complex in GG-NER
0.0 0.5 REACTOME_OTHER_SEMAPHORIN_INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.2 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.4 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism