Motif ID: Cebpe

Z-value: 1.028


Transcription factors associated with Cebpe:

Gene SymbolEntrez IDGene Name
Cebpe ENSMUSG00000052435.6 Cebpe



Activity profile for motif Cebpe.

activity profile for motif Cebpe


Sorted Z-values histogram for motif Cebpe

Sorted Z-values for motif Cebpe



Network of associatons between targets according to the STRING database.



First level regulatory network of Cebpe

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 5.260 ENSMUST00000033229.3
Hbb-y
hemoglobin Y, beta-like embryonic chain
chr14_+_50944499 4.906 ENSMUST00000178092.1
Pnp
purine-nucleoside phosphorylase
chr10_-_92165159 3.618 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr19_+_60144682 3.047 ENSMUST00000065383.4
E330013P04Rik
RIKEN cDNA E330013P04 gene
chr9_-_100506844 2.643 ENSMUST00000112874.3
Nck1
non-catalytic region of tyrosine kinase adaptor protein 1
chr7_+_67647405 2.611 ENSMUST00000032774.8
ENSMUST00000107471.1
Ttc23

tetratricopeptide repeat domain 23

chrX_+_112311334 2.479 ENSMUST00000026599.3
ENSMUST00000113415.1
Apool

apolipoprotein O-like

chr4_+_124986430 2.279 ENSMUST00000030687.7
Rspo1
R-spondin homolog (Xenopus laevis)
chr12_-_10900296 2.241 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr1_+_146420434 2.115 ENSMUST00000163646.1
Gm5263
predicted gene 5263
chr17_+_80127447 1.949 ENSMUST00000039205.4
Galm
galactose mutarotase
chr10_-_45470201 1.869 ENSMUST00000079390.6
Lin28b
lin-28 homolog B (C. elegans)
chr8_+_116504973 1.742 ENSMUST00000078170.5
Dynlrb2
dynein light chain roadblock-type 2
chr11_-_76399107 1.731 ENSMUST00000021204.3
Nxn
nucleoredoxin
chr16_-_22161450 1.705 ENSMUST00000115379.1
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr6_+_5390387 1.680 ENSMUST00000183358.1
Asb4
ankyrin repeat and SOCS box-containing 4
chr11_-_6444352 1.650 ENSMUST00000093346.5
ENSMUST00000109737.2
H2afv

H2A histone family, member V

chr2_+_122147680 1.632 ENSMUST00000102476.4
B2m
beta-2 microglobulin
chr9_-_114781986 1.622 ENSMUST00000035009.8
ENSMUST00000084867.7
Cmtm7

CKLF-like MARVEL transmembrane domain containing 7

chr7_-_42578588 1.614 ENSMUST00000179470.1
Gm21028
predicted gene, 21028

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 273 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 6.1 GO:0015671 oxygen transport(GO:0015671)
0.7 5.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
1.6 4.9 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 4.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 3.0 GO:2000254 regulation of male germ cell proliferation(GO:2000254)
0.1 2.8 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.9 2.6 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 2.6 GO:0006342 chromatin silencing(GO:0006342)
0.2 2.5 GO:0042407 cristae formation(GO:0042407)
0.1 2.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 2.3 GO:0051028 mRNA transport(GO:0051028)
0.4 1.9 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.2 1.9 GO:0010587 miRNA catabolic process(GO:0010587)
0.4 1.8 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 1.7 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.4 1.6 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 1.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 1.5 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.5 1.4 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.2 1.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 131 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 6.1 GO:0005833 hemoglobin complex(GO:0005833)
0.1 4.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 3.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 3.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 2.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 2.7 GO:0000786 nucleosome(GO:0000786)
0.3 2.5 GO:0061617 MICOS complex(GO:0061617)
0.2 2.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 2.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.4 2.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 2.2 GO:0000776 kinetochore(GO:0000776)
0.2 1.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 1.7 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 1.7 GO:0036157 outer dynein arm(GO:0036157)
0.1 1.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.2 1.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 1.4 GO:0031970 organelle envelope lumen(GO:0031970)
0.0 1.4 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 186 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 6.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.5 6.1 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.1 3.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 3.0 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 2.8 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.4 2.7 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 2.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 2.2 GO:0008201 heparin binding(GO:0008201)
0.0 2.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.2 1.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.9 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.8 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 1.7 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.2 1.7 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.2 1.7 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 1.7 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 1.7 GO:0005158 insulin receptor binding(GO:0005158)
0.2 1.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 1.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.8 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.1 3.9 PID_BARD1_PATHWAY BARD1 signaling events
0.0 3.9 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.4 PID_VEGFR1_PATHWAY VEGFR1 specific signals
0.1 2.9 PID_WNT_SIGNALING_PATHWAY Wnt signaling network
0.0 2.6 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.1 2.5 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 1.7 PID_IL12_2PATHWAY IL12-mediated signaling events
0.0 1.5 PID_SMAD2_3NUCLEAR_PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 1.4 PID_IL27_PATHWAY IL27-mediated signaling events
0.0 1.0 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 1.0 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.9 PID_ERBB1_DOWNSTREAM_PATHWAY ErbB1 downstream signaling
0.0 0.8 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.8 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.7 PID_ATM_PATHWAY ATM pathway
0.0 0.7 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.7 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 68 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.5 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.5 6.0 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 5.4 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 5.3 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 5.0 REACTOME_MEIOTIC_RECOMBINATION Genes involved in Meiotic Recombination
0.2 2.6 REACTOME_ACTIVATION_OF_RAC Genes involved in Activation of Rac
0.1 2.5 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 2.5 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.1 2.2 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.8 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.5 1.6 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.6 REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.5 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.1 1.5 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.4 REACTOME_CA_DEPENDENT_EVENTS Genes involved in Ca-dependent events
0.1 1.3 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.1 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 1.1 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.0 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.0 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation