Motif ID: Ctcfl_Ctcf
Z-value: 1.113
Transcription factors associated with Ctcfl_Ctcf:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Ctcf | ENSMUSG00000005698.9 | Ctcf |
| Ctcfl | ENSMUSG00000070495.5 | Ctcfl |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Ctcf | mm10_v2_chr8_+_105636509_105636589 | 0.61 | 7.7e-03 | Click! |
| Ctcfl | mm10_v2_chr2_-_173119402_173119525 | -0.01 | 9.6e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 5.1 | GO:0051542 | elastin biosynthetic process(GO:0051542) |
| 1.3 | 5.2 | GO:0044268 | multicellular organismal protein metabolic process(GO:0044268) |
| 1.1 | 3.4 | GO:0016256 | N-glycan processing to lysosome(GO:0016256) |
| 0.9 | 2.6 | GO:0043181 | vacuolar sequestering(GO:0043181) |
| 0.9 | 7.9 | GO:1900034 | regulation of cellular response to heat(GO:1900034) |
| 0.7 | 2.2 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.7 | 3.6 | GO:0002121 | inter-male aggressive behavior(GO:0002121) |
| 0.6 | 1.9 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 0.6 | 1.8 | GO:2000344 | positive regulation of acrosome reaction(GO:2000344) |
| 0.6 | 4.1 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 0.5 | 1.6 | GO:0032241 | positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) |
| 0.5 | 2.1 | GO:1901492 | positive regulation of lymphangiogenesis(GO:1901492) |
| 0.5 | 2.1 | GO:0099566 | regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566) |
| 0.5 | 2.5 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313) |
| 0.4 | 1.3 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.4 | 1.2 | GO:1903348 | positive regulation of bicellular tight junction assembly(GO:1903348) |
| 0.4 | 3.1 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.4 | 1.1 | GO:0050925 | negative regulation of negative chemotaxis(GO:0050925) |
| 0.3 | 1.0 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) |
| 0.3 | 2.3 | GO:0060666 | dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666) |
| 0.3 | 1.7 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.3 | 1.3 | GO:0072362 | regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362) |
| 0.3 | 1.5 | GO:2001015 | negative regulation of skeletal muscle cell differentiation(GO:2001015) |
| 0.3 | 0.9 | GO:0035973 | aggrephagy(GO:0035973) |
| 0.3 | 0.8 | GO:1904569 | regulation of selenocysteine incorporation(GO:1904569) |
| 0.3 | 0.8 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
| 0.2 | 0.7 | GO:0003289 | endocardial cushion fusion(GO:0003274) atrial septum primum morphogenesis(GO:0003289) |
| 0.2 | 1.9 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.2 | 0.7 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
| 0.2 | 0.6 | GO:0051892 | negative regulation of cardioblast differentiation(GO:0051892) |
| 0.2 | 0.6 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
| 0.2 | 1.0 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 0.2 | 1.2 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.2 | 1.8 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.2 | 1.2 | GO:0071630 | nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630) |
| 0.2 | 0.8 | GO:0035624 | receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) |
| 0.2 | 0.7 | GO:0021882 | regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) |
| 0.2 | 1.1 | GO:0003383 | apical constriction(GO:0003383) |
| 0.2 | 0.4 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 0.2 | 1.0 | GO:0098964 | dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964) |
| 0.2 | 0.9 | GO:0001705 | ectoderm formation(GO:0001705) ectodermal cell differentiation(GO:0010668) |
| 0.2 | 0.5 | GO:0048209 | regulation of vesicle targeting, to, from or within Golgi(GO:0048209) |
| 0.2 | 0.7 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 0.2 | 3.0 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.2 | 0.3 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 0.2 | 2.2 | GO:0034472 | snRNA 3'-end processing(GO:0034472) |
| 0.2 | 1.2 | GO:1903207 | neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208) |
| 0.2 | 0.6 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) |
| 0.1 | 0.7 | GO:0010637 | diet induced thermogenesis(GO:0002024) negative regulation of mitochondrial fusion(GO:0010637) |
| 0.1 | 0.4 | GO:0018008 | N-terminal peptidyl-glycine N-myristoylation(GO:0018008) |
| 0.1 | 1.6 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
| 0.1 | 0.3 | GO:0034140 | negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) |
| 0.1 | 0.4 | GO:0045113 | regulation of integrin biosynthetic process(GO:0045113) |
| 0.1 | 3.2 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.1 | 1.2 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.1 | 0.4 | GO:1904017 | response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.1 | 0.4 | GO:0072425 | signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) |
| 0.1 | 2.5 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.1 | 1.0 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.1 | 0.4 | GO:0045163 | clustering of voltage-gated potassium channels(GO:0045163) |
| 0.1 | 0.6 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
| 0.1 | 2.4 | GO:0042297 | vocal learning(GO:0042297) imitative learning(GO:0098596) |
| 0.1 | 1.2 | GO:0030432 | peristalsis(GO:0030432) |
| 0.1 | 0.8 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.1 | 0.3 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
| 0.1 | 0.8 | GO:0032380 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 0.1 | 2.0 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.1 | 0.7 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.1 | 2.5 | GO:0032933 | response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501) |
| 0.1 | 3.6 | GO:0061098 | positive regulation of protein tyrosine kinase activity(GO:0061098) |
| 0.1 | 0.3 | GO:0060022 | noradrenergic neuron differentiation(GO:0003357) hard palate development(GO:0060022) soft palate development(GO:0060023) |
| 0.1 | 0.5 | GO:0098703 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
| 0.1 | 3.6 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 0.1 | 0.5 | GO:1902998 | macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 0.1 | 0.4 | GO:0071883 | activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883) |
| 0.1 | 1.6 | GO:0047497 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
| 0.1 | 0.5 | GO:1903336 | negative regulation of vacuolar transport(GO:1903336) |
| 0.1 | 0.4 | GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) |
| 0.1 | 1.5 | GO:0035721 | intraciliary retrograde transport(GO:0035721) |
| 0.1 | 0.9 | GO:0051683 | establishment of Golgi localization(GO:0051683) |
| 0.1 | 0.3 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.1 | 0.3 | GO:0006751 | glutathione catabolic process(GO:0006751) |
| 0.1 | 1.5 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.1 | 0.6 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.1 | 0.2 | GO:0006097 | glyoxylate cycle(GO:0006097) |
| 0.1 | 0.3 | GO:0046898 | response to cycloheximide(GO:0046898) |
| 0.1 | 0.8 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.1 | 0.7 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
| 0.1 | 1.2 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.1 | 0.8 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
| 0.1 | 0.2 | GO:0060854 | patterning of lymph vessels(GO:0060854) |
| 0.1 | 10.7 | GO:0007416 | synapse assembly(GO:0007416) |
| 0.1 | 0.6 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.1 | 0.3 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
| 0.1 | 0.5 | GO:0045075 | interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075) |
| 0.1 | 0.2 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 0.1 | 0.7 | GO:2000651 | positive regulation of sodium ion transmembrane transporter activity(GO:2000651) |
| 0.1 | 0.9 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 1.5 | GO:0014065 | phosphatidylinositol 3-kinase signaling(GO:0014065) |
| 0.1 | 1.2 | GO:0001539 | cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285) |
| 0.1 | 0.3 | GO:0035234 | ectopic germ cell programmed cell death(GO:0035234) |
| 0.1 | 0.2 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
| 0.1 | 0.2 | GO:0000448 | cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) |
| 0.1 | 0.3 | GO:0097646 | dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 0.1 | 0.9 | GO:0099612 | protein localization to axon(GO:0099612) |
| 0.1 | 0.2 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 0.1 | 0.3 | GO:1902775 | mitochondrial large ribosomal subunit assembly(GO:1902775) |
| 0.1 | 1.2 | GO:0030818 | negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of cAMP biosynthetic process(GO:0030818) |
| 0.1 | 0.1 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
| 0.1 | 0.8 | GO:2001275 | positive regulation of glucose import in response to insulin stimulus(GO:2001275) |
| 0.1 | 0.6 | GO:1901096 | regulation of autophagosome maturation(GO:1901096) |
| 0.1 | 1.1 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.0 | 0.4 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.0 | 0.5 | GO:0035520 | monoubiquitinated protein deubiquitination(GO:0035520) |
| 0.0 | 1.0 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.0 | 1.4 | GO:0060765 | regulation of androgen receptor signaling pathway(GO:0060765) |
| 0.0 | 0.2 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.0 | 0.1 | GO:0098974 | postsynaptic actin cytoskeleton organization(GO:0098974) |
| 0.0 | 1.7 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.0 | 0.6 | GO:0032957 | inositol trisphosphate metabolic process(GO:0032957) |
| 0.0 | 0.8 | GO:0086010 | membrane depolarization during action potential(GO:0086010) |
| 0.0 | 0.2 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.0 | 0.2 | GO:0006776 | vitamin A metabolic process(GO:0006776) positive regulation of skeletal muscle tissue regeneration(GO:0043415) |
| 0.0 | 0.8 | GO:0014898 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898) |
| 0.0 | 1.7 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.0 | 0.2 | GO:0090073 | positive regulation of protein homodimerization activity(GO:0090073) |
| 0.0 | 0.6 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.0 | 0.3 | GO:0071816 | tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
| 0.0 | 0.3 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.0 | 0.1 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.0 | 0.2 | GO:0035280 | miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280) |
| 0.0 | 0.1 | GO:0019074 | viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074) |
| 0.0 | 0.3 | GO:0045607 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
| 0.0 | 0.6 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 1.9 | GO:0035725 | sodium ion transmembrane transport(GO:0035725) |
| 0.0 | 0.1 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
| 0.0 | 0.2 | GO:0045351 | type I interferon biosynthetic process(GO:0045351) |
| 0.0 | 0.2 | GO:0010807 | regulation of synaptic vesicle priming(GO:0010807) |
| 0.0 | 0.2 | GO:0006924 | activation-induced cell death of T cells(GO:0006924) |
| 0.0 | 0.3 | GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) |
| 0.0 | 0.1 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 0.0 | 0.1 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.0 | 0.5 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
| 0.0 | 0.2 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 0.0 | 0.3 | GO:0001675 | acrosome assembly(GO:0001675) intermediate filament organization(GO:0045109) |
| 0.0 | 0.7 | GO:0015813 | L-glutamate transport(GO:0015813) |
| 0.0 | 1.0 | GO:0050919 | negative chemotaxis(GO:0050919) |
| 0.0 | 0.2 | GO:0042346 | positive regulation of NF-kappaB import into nucleus(GO:0042346) |
| 0.0 | 0.2 | GO:0032026 | response to magnesium ion(GO:0032026) |
| 0.0 | 0.4 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
| 0.0 | 0.1 | GO:1900244 | positive regulation of synaptic vesicle endocytosis(GO:1900244) |
| 0.0 | 0.6 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.0 | 0.5 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
| 0.0 | 0.6 | GO:2000758 | positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758) |
| 0.0 | 0.1 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.0 | 0.1 | GO:1901838 | positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) |
| 0.0 | 0.2 | GO:1902414 | protein localization to cell junction(GO:1902414) |
| 0.0 | 1.6 | GO:0051453 | regulation of intracellular pH(GO:0051453) |
| 0.0 | 0.1 | GO:0072718 | response to cisplatin(GO:0072718) |
| 0.0 | 0.1 | GO:1901386 | negative regulation of voltage-gated calcium channel activity(GO:1901386) |
| 0.0 | 0.1 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 0.0 | 1.3 | GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178) |
| 0.0 | 0.3 | GO:0009303 | rRNA transcription(GO:0009303) |
| 0.0 | 0.2 | GO:0006450 | regulation of translational fidelity(GO:0006450) |
| 0.0 | 0.1 | GO:1901727 | positive regulation of histone deacetylase activity(GO:1901727) |
| 0.0 | 0.3 | GO:0019369 | arachidonic acid metabolic process(GO:0019369) |
| 0.0 | 0.2 | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241) |
| 0.0 | 0.1 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.2 | GO:0010666 | positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666) |
| 0.0 | 0.3 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.0 | 0.5 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.0 | 0.2 | GO:0009191 | ribonucleoside diphosphate catabolic process(GO:0009191) |
| 0.0 | 0.1 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.0 | 0.0 | GO:0018343 | protein farnesylation(GO:0018343) |
| 0.0 | 0.3 | GO:0042491 | auditory receptor cell differentiation(GO:0042491) |
| 0.0 | 3.7 | GO:0015711 | organic anion transport(GO:0015711) |
| 0.0 | 0.9 | GO:0009612 | response to mechanical stimulus(GO:0009612) |
| 0.0 | 1.8 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.0 | 0.2 | GO:0044458 | motile cilium assembly(GO:0044458) |
| 0.0 | 0.6 | GO:0001658 | branching involved in ureteric bud morphogenesis(GO:0001658) |
| 0.0 | 1.4 | GO:0006869 | lipid transport(GO:0006869) |
| 0.0 | 1.8 | GO:0007411 | axon guidance(GO:0007411) |
| 0.0 | 0.1 | GO:0051481 | negative regulation of cytosolic calcium ion concentration(GO:0051481) |
| 0.0 | 0.2 | GO:0061036 | positive regulation of cartilage development(GO:0061036) |
| 0.0 | 0.2 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 7.9 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.6 | 1.9 | GO:0098855 | HCN channel complex(GO:0098855) |
| 0.5 | 2.3 | GO:0044316 | cone cell pedicle(GO:0044316) |
| 0.4 | 1.9 | GO:0005683 | U7 snRNP(GO:0005683) |
| 0.4 | 6.2 | GO:0043196 | varicosity(GO:0043196) |
| 0.4 | 1.1 | GO:0097233 | lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233) |
| 0.3 | 1.6 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.3 | 0.9 | GO:1990075 | kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075) |
| 0.3 | 0.9 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 0.3 | 4.2 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.3 | 2.1 | GO:0097433 | dense body(GO:0097433) |
| 0.2 | 1.2 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.2 | 3.0 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.2 | 0.7 | GO:0048179 | activin receptor complex(GO:0048179) |
| 0.2 | 2.1 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.2 | 0.9 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.2 | 1.1 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.2 | 0.4 | GO:0002142 | stereocilia ankle link complex(GO:0002142) |
| 0.2 | 1.0 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 0.2 | 2.2 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.2 | 0.8 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.2 | 1.5 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.2 | 2.0 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.1 | 2.4 | GO:0032039 | integrator complex(GO:0032039) |
| 0.1 | 2.1 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 0.5 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.1 | 0.7 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.1 | 0.4 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 0.1 | 0.6 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.1 | 3.5 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.1 | 3.7 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.1 | 1.6 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.1 | 0.2 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
| 0.1 | 0.4 | GO:1903440 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 0.1 | 0.5 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
| 0.1 | 0.4 | GO:0031045 | dense core granule(GO:0031045) |
| 0.1 | 2.9 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 0.5 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.1 | 0.1 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
| 0.1 | 0.3 | GO:0071556 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
| 0.1 | 0.9 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.1 | 1.0 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.1 | 0.8 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 1.4 | GO:0043218 | compact myelin(GO:0043218) |
| 0.1 | 0.1 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.1 | 0.3 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.1 | 0.6 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.1 | 0.7 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 0.3 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.1 | 1.1 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 1.5 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.0 | 3.6 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 1.8 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.0 | 2.3 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 2.0 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.0 | 1.2 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 8.2 | GO:0070382 | exocytic vesicle(GO:0070382) |
| 0.0 | 0.7 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.0 | 0.8 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 7.1 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.0 | 0.4 | GO:0090543 | ESCRT III complex(GO:0000815) Flemming body(GO:0090543) |
| 0.0 | 0.3 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.0 | 0.7 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.0 | 0.2 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.0 | 0.6 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.0 | 7.0 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.0 | 1.0 | GO:0005684 | U2-type spliceosomal complex(GO:0005684) |
| 0.0 | 4.5 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 0.2 | GO:0070578 | RISC-loading complex(GO:0070578) |
| 0.0 | 1.8 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 0.2 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 2.0 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 2.0 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 0.1 | GO:0030137 | COPI-coated vesicle(GO:0030137) |
| 0.0 | 0.2 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 1.2 | GO:0030659 | cytoplasmic vesicle membrane(GO:0030659) |
| 0.0 | 3.4 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.0 | 0.1 | GO:0060293 | P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293) |
| 0.0 | 0.3 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 0.2 | GO:0030125 | clathrin vesicle coat(GO:0030125) |
| 0.0 | 0.4 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.0 | 0.1 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.0 | 10.9 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 0.2 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.0 | 0.0 | GO:0005965 | protein farnesyltransferase complex(GO:0005965) |
| 0.0 | 0.1 | GO:0034704 | calcium channel complex(GO:0034704) |
| 0.0 | 0.1 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.0 | 0.4 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.0 | 0.6 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 1.6 | GO:0030426 | growth cone(GO:0030426) |
| 0.0 | 0.7 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.4 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 0.1 | GO:0016589 | NURF complex(GO:0016589) |
| 0.0 | 0.1 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 5.2 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 1.1 | 7.9 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 1.1 | 3.2 | GO:0043682 | copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682) |
| 1.0 | 4.2 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.9 | 2.6 | GO:0004574 | oligo-1,6-glucosidase activity(GO:0004574) |
| 0.9 | 3.4 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 0.6 | 1.9 | GO:0071209 | U7 snRNA binding(GO:0071209) |
| 0.6 | 6.2 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
| 0.5 | 2.0 | GO:0035473 | lipase binding(GO:0035473) |
| 0.5 | 1.8 | GO:0008332 | low voltage-gated calcium channel activity(GO:0008332) |
| 0.4 | 1.7 | GO:0051377 | mannose-ethanolamine phosphotransferase activity(GO:0051377) |
| 0.4 | 3.2 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.3 | 3.1 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.3 | 1.2 | GO:0001602 | pancreatic polypeptide receptor activity(GO:0001602) |
| 0.3 | 0.9 | GO:0051765 | inositol tetrakisphosphate kinase activity(GO:0051765) |
| 0.3 | 2.7 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.3 | 1.6 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 0.3 | 0.8 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
| 0.3 | 0.8 | GO:0004936 | alpha-adrenergic receptor activity(GO:0004936) epinephrine binding(GO:0051379) |
| 0.2 | 0.7 | GO:0015173 | hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 0.2 | 4.2 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) |
| 0.2 | 1.1 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.2 | 1.6 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.2 | 3.0 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.2 | 0.7 | GO:0016361 | activin receptor activity, type I(GO:0016361) |
| 0.2 | 0.5 | GO:0001888 | glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888) |
| 0.2 | 1.0 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.2 | 1.3 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
| 0.1 | 0.6 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 0.1 | 0.9 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
| 0.1 | 0.4 | GO:0019107 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107) |
| 0.1 | 1.0 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.1 | 0.5 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.1 | 1.2 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.1 | 0.4 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
| 0.1 | 0.3 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.1 | 0.5 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
| 0.1 | 0.3 | GO:0003986 | acetyl-CoA hydrolase activity(GO:0003986) |
| 0.1 | 1.5 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.1 | 0.6 | GO:0043426 | MRF binding(GO:0043426) |
| 0.1 | 0.8 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.1 | 1.2 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.1 | 0.4 | GO:0097643 | amylin receptor activity(GO:0097643) |
| 0.1 | 1.5 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.1 | 1.1 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.1 | 0.2 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 0.1 | 4.7 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.1 | 2.1 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 0.4 | GO:0005250 | A-type (transient outward) potassium channel activity(GO:0005250) |
| 0.1 | 0.2 | GO:0004448 | isocitrate dehydrogenase activity(GO:0004448) isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.1 | 0.2 | GO:0001225 | RNA polymerase II transcription coactivator binding(GO:0001225) |
| 0.1 | 3.1 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.1 | 0.4 | GO:0033142 | progesterone receptor binding(GO:0033142) |
| 0.1 | 1.0 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 0.6 | GO:0003847 | 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847) |
| 0.1 | 1.9 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 0.3 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.1 | 0.6 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.1 | 0.1 | GO:0031750 | D3 dopamine receptor binding(GO:0031750) |
| 0.1 | 0.9 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.1 | 0.4 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.1 | 5.6 | GO:0042626 | ATPase activity, coupled to transmembrane movement of substances(GO:0042626) |
| 0.1 | 0.6 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.1 | 0.3 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.1 | 0.4 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.1 | 2.5 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.1 | 0.7 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
| 0.0 | 0.4 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
| 0.0 | 0.3 | GO:0008242 | omega peptidase activity(GO:0008242) |
| 0.0 | 0.9 | GO:0034483 | heparan sulfate sulfotransferase activity(GO:0034483) |
| 0.0 | 2.2 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 0.2 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
| 0.0 | 1.9 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.1 | GO:0098973 | structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973) |
| 0.0 | 1.7 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 5.2 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.8 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 0.2 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.0 | 0.3 | GO:0016215 | acyl-CoA desaturase activity(GO:0016215) |
| 0.0 | 0.9 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.3 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
| 0.0 | 0.2 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.0 | 0.4 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.0 | 0.3 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.0 | 0.5 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 0.0 | 1.6 | GO:0004177 | aminopeptidase activity(GO:0004177) |
| 0.0 | 0.3 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.0 | 0.3 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.0 | 0.2 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.0 | 0.3 | GO:0097153 | cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.0 | 0.3 | GO:0031005 | filamin binding(GO:0031005) |
| 0.0 | 0.1 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.0 | 1.4 | GO:0097110 | scaffold protein binding(GO:0097110) |
| 0.0 | 0.9 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.0 | 0.1 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
| 0.0 | 2.0 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.1 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
| 0.0 | 1.0 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.0 | 2.8 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 1.2 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 0.2 | GO:0051731 | polynucleotide 5'-hydroxyl-kinase activity(GO:0051731) |
| 0.0 | 0.2 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.0 | 0.1 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
| 0.0 | 0.1 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
| 0.0 | 0.4 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.0 | 0.0 | GO:0004660 | protein farnesyltransferase activity(GO:0004660) |
| 0.0 | 1.0 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 0.4 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 0.0 | 0.3 | GO:0004629 | phospholipase C activity(GO:0004629) |
| 0.0 | 4.8 | GO:0030695 | GTPase regulator activity(GO:0030695) |
| 0.0 | 0.1 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.0 | 0.9 | GO:0017022 | myosin binding(GO:0017022) |
| 0.0 | 1.0 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 0.1 | GO:0008853 | exodeoxyribonuclease III activity(GO:0008853) |
| 0.0 | 0.2 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
| 0.0 | 0.2 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.0 | 0.1 | GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
| 0.0 | 0.2 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.0 | 1.1 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 0.1 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.0 | 0.2 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.2 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.0 | 0.1 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 7.9 | PID_P38_GAMMA_DELTA_PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.3 | 3.7 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
| 0.2 | 6.8 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.1 | 1.9 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.1 | 2.5 | SA_CASPASE_CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.1 | 1.3 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
| 0.1 | 3.7 | PID_REELIN_PATHWAY | Reelin signaling pathway |
| 0.1 | 2.2 | PID_MYC_PATHWAY | C-MYC pathway |
| 0.1 | 2.7 | PID_NCADHERIN_PATHWAY | N-cadherin signaling events |
| 0.1 | 4.3 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
| 0.1 | 0.7 | PID_ALK2_PATHWAY | ALK2 signaling events |
| 0.1 | 3.8 | PID_RAC1_REG_PATHWAY | Regulation of RAC1 activity |
| 0.1 | 1.5 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
| 0.0 | 0.9 | PID_NECTIN_PATHWAY | Nectin adhesion pathway |
| 0.0 | 3.0 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 0.4 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
| 0.0 | 1.3 | PID_SHP2_PATHWAY | SHP2 signaling |
| 0.0 | 3.4 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 1.0 | PID_A6B1_A6B4_INTEGRIN_PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.0 | 1.0 | PID_AJDISS_2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 0.7 | PID_PI3KCI_AKT_PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.0 | 0.6 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.4 | PID_IGF1_PATHWAY | IGF1 pathway |
| 0.0 | 0.3 | PID_HIV_NEF_PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.0 | 0.4 | PID_THROMBIN_PAR1_PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 0.4 | PID_PTP1B_PATHWAY | Signaling events mediated by PTP1B |
| 0.0 | 0.5 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.4 | ST_TUMOR_NECROSIS_FACTOR_PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.6 | PID_LKB1_PATHWAY | LKB1 signaling events |
| 0.0 | 0.3 | PID_FAS_PATHWAY | FAS (CD95) signaling pathway |
| 0.0 | 0.5 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 7.9 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.2 | 3.0 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.2 | 3.7 | REACTOME_HYALURONAN_METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.2 | 4.4 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
| 0.2 | 4.6 | REACTOME_CRMPS_IN_SEMA3A_SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.2 | 0.4 | REACTOME_EICOSANOID_LIGAND_BINDING_RECEPTORS | Genes involved in Eicosanoid ligand-binding receptors |
| 0.2 | 5.2 | REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 0.1 | 1.6 | REACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS | Genes involved in Nucleotide-like (purinergic) receptors |
| 0.1 | 4.4 | REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 2.5 | REACTOME_NEPHRIN_INTERACTIONS | Genes involved in Nephrin interactions |
| 0.1 | 1.8 | REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.1 | 1.3 | REACTOME_P38MAPK_EVENTS | Genes involved in p38MAPK events |
| 0.1 | 1.6 | REACTOME_REGULATION_OF_SIGNALING_BY_CBL | Genes involved in Regulation of signaling by CBL |
| 0.1 | 2.1 | REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.1 | 1.1 | REACTOME_ACTIVATION_OF_RAC | Genes involved in Activation of Rac |
| 0.1 | 1.9 | REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.1 | 1.0 | REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.1 | 5.8 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 0.6 | REACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION_IN_TLR7_8_OR_9_SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.1 | 1.3 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
| 0.1 | 1.2 | REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.1 | 0.4 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.1 | 1.7 | REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.1 | 1.3 | REACTOME_FRS2_MEDIATED_CASCADE | Genes involved in FRS2-mediated cascade |
| 0.1 | 2.6 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 1.7 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 5.0 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
| 0.0 | 1.2 | REACTOME_TIGHT_JUNCTION_INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.2 | REACTOME_NUCLEAR_SIGNALING_BY_ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.0 | 1.8 | REACTOME_NCAM1_INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 3.6 | REACTOME_POTASSIUM_CHANNELS | Genes involved in Potassium Channels |
| 0.0 | 0.7 | REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.0 | 0.7 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 0.3 | REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.0 | 0.3 | REACTOME_INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.0 | 0.6 | REACTOME_NUCLEOTIDE_BINDING_DOMAIN_LEUCINE_RICH_REPEAT_CONTAINING_RECEPTOR_NLR_SIGNALING_PATHWAYS | Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways |
| 0.0 | 0.8 | REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.9 | REACTOME_HS_GAG_BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.3 | REACTOME_ALPHA_LINOLENIC_ACID_ALA_METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.0 | 2.3 | REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.7 | REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 0.2 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.0 | 0.6 | REACTOME_INTERFERON_ALPHA_BETA_SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 0.5 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.3 | REACTOME_RNA_POL_III_CHAIN_ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.0 | 0.7 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.0 | 0.3 | REACTOME_GLUTATHIONE_CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 0.2 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 0.2 | REACTOME_PEROXISOMAL_LIPID_METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.0 | 0.2 | REACTOME_MTORC1_MEDIATED_SIGNALLING | Genes involved in mTORC1-mediated signalling |
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