Motif ID: Dbp

Z-value: 1.049


Transcription factors associated with Dbp:

Gene SymbolEntrez IDGene Name
Dbp ENSMUSG00000059824.4 Dbp

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dbpmm10_v2_chr7_+_45705088_457052920.522.6e-02Click!


Activity profile for motif Dbp.

activity profile for motif Dbp


Sorted Z-values histogram for motif Dbp

Sorted Z-values for motif Dbp



Network of associatons between targets according to the STRING database.



First level regulatory network of Dbp

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_80802789 5.286 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr10_+_123264076 4.560 ENSMUST00000050756.7
 Fam19a2
family with sequence similarity 19, member A2
chr16_+_7069825 4.383 ENSMUST00000056416.7
 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr5_+_117781017 3.292 ENSMUST00000138579.2
 Nos1
nitric oxide synthase 1, neuronal
chr19_-_28911879 3.284 ENSMUST00000179171.1
 AC163993.1
AC163993.1
chr12_-_83487708 3.054 ENSMUST00000177959.1
ENSMUST00000178756.1
 Dpf3

D4, zinc and double PHD fingers, family 3

chr3_-_26133734 3.019 ENSMUST00000108308.3
ENSMUST00000075054.4
 Nlgn1

neuroligin 1

chr1_+_66386968 2.858 ENSMUST00000145419.1
 Map2
microtubule-associated protein 2
chr5_+_150259922 2.820 ENSMUST00000087204.5
 Fry
furry homolog (Drosophila)
chr14_-_30353468 2.775 ENSMUST00000112249.1
 Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr13_-_84064772 2.707 ENSMUST00000182477.1
 Gm17750
predicted gene, 17750
chr16_+_91225550 2.553 ENSMUST00000035608.8
 Olig2
oligodendrocyte transcription factor 2
chr14_-_102982630 2.492 ENSMUST00000184744.1
 KCTD12
mmu-mir-5130
chr9_-_49798905 2.382 ENSMUST00000114476.2
 Ncam1
neural cell adhesion molecule 1
chr19_+_26748268 2.221 ENSMUST00000175791.1
ENSMUST00000176698.1
ENSMUST00000177252.1
ENSMUST00000176475.1
ENSMUST00000112637.2
 Smarca2




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2




chr2_+_65845833 2.131 ENSMUST00000053910.3
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr5_+_134986191 2.054 ENSMUST00000094245.2
 Cldn3
claudin 3
chr5_-_44799643 2.024 ENSMUST00000070748.5
 Ldb2
LIM domain binding 2
chr8_+_70501116 2.015 ENSMUST00000127983.1
 Crlf1
cytokine receptor-like factor 1
chr8_-_115707778 1.961 ENSMUST00000109104.1
 Maf
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 121 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 6.3 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923)
0.2 5.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.4 4.9 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 4.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 4.3 GO:0007416 synapse assembly(GO:0007416)
1.4 4.2 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.0 3.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.4 3.5 GO:0061368 maternal process involved in parturition(GO:0060137) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2 3.5 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.4 3.3 GO:0097264 self proteolysis(GO:0097264)
0.4 3.2 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.4 3.2 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 3.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.3 3.0 GO:0071420 cellular response to histamine(GO:0071420)
0.7 2.8 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.3 2.8 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.1 2.7 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.9 2.6 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 2.5 GO:0021540 corpus callosum morphogenesis(GO:0021540)
0.0 2.4 GO:0006487 protein N-linked glycosylation(GO:0006487)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 9.6 GO:0030427 site of polarized growth(GO:0030427)
0.3 8.5 GO:0071565 nBAF complex(GO:0071565)
0.4 7.9 GO:0032279 asymmetric synapse(GO:0032279)
0.0 4.0 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 3.7 GO:0005802 trans-Golgi network(GO:0005802)
0.3 3.3 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.2 3.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.3 2.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.3 2.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 2.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.5 2.1 GO:0031673 H zone(GO:0031673)
0.1 2.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 1.8 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 1.8 GO:0005902 microvillus(GO:0005902)
0.1 1.7 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.7 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.6 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.6 GO:0001650 fibrillar center(GO:0001650)
0.0 1.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 86 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.8 GO:0005509 calcium ion binding(GO:0005509)
0.9 6.6 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 4.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 4.2 GO:0030275 LRR domain binding(GO:0030275)
0.0 3.9 GO:0017137 Rab GTPase binding(GO:0017137)
1.1 3.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.2 3.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 3.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.4 2.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.3 2.8 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1 2.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 2.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 2.7 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 2.5 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.4 2.4 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 2.4 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.2 2.0 GO:0030274 LIM domain binding(GO:0030274)
0.2 2.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.4 1.8 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 1.8 GO:0051010 microtubule plus-end binding(GO:0051010)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.3 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.1 4.2 PID_FGF_PATHWAY FGF signaling pathway
0.1 3.5 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 3.1 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.9 ST_GRANULE_CELL_SURVIVAL_PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 2.8 PID_AR_TF_PATHWAY Regulation of Androgen receptor activity
0.0 2.7 PID_LKB1_PATHWAY LKB1 signaling events
0.0 2.6 PID_TRKR_PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.1 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.8 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 1.3 PID_CDC42_PATHWAY CDC42 signaling events
0.0 1.2 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.1 ST_MYOCYTE_AD_PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 0.9 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 0.7 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.7 PID_ERA_GENOMIC_PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 0.6 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.6 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 32 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 9.8 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 6.5 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.1 4.6 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 4.1 REACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.2 3.8 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT Genes involved in Ligand-gated ion channel transport
0.2 3.6 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.4 REACTOME_DARPP_32_EVENTS Genes involved in DARPP-32 events
0.1 2.1 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 2.1 REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION Genes involved in Downstream signal transduction
0.1 1.8 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.7 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.7 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.5 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.4 REACTOME_EGFR_DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.3 REACTOME_POTASSIUM_CHANNELS Genes involved in Potassium Channels
0.1 1.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.2 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.2 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.1 REACTOME_DOWNSTREAM_TCR_SIGNALING Genes involved in Downstream TCR signaling
0.0 1.1 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions