Motif ID: Dlx5_Dlx4
Z-value: 1.007
Transcription factors associated with Dlx5_Dlx4:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Dlx4 | ENSMUSG00000020871.7 | Dlx4 |
Dlx5 | ENSMUSG00000029755.9 | Dlx5 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Dlx5 | mm10_v2_chr6_-_6882068_6882092 | 0.07 | 7.9e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 5.6 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
0.7 | 2.0 | GO:1904956 | regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041) |
0.5 | 1.4 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
0.4 | 1.5 | GO:0015825 | L-serine transport(GO:0015825) |
0.4 | 1.8 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
0.3 | 0.9 | GO:1904395 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
0.3 | 0.9 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
0.3 | 0.9 | GO:0032474 | otolith morphogenesis(GO:0032474) |
0.3 | 0.3 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
0.3 | 1.4 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
0.3 | 0.8 | GO:0072139 | glomerular parietal epithelial cell differentiation(GO:0072139) |
0.3 | 0.8 | GO:0060598 | dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598) |
0.3 | 1.0 | GO:0006742 | NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) |
0.2 | 0.7 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
0.2 | 0.7 | GO:0060023 | soft palate development(GO:0060023) |
0.2 | 0.7 | GO:0019046 | release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382) |
0.2 | 0.7 | GO:0061743 | motor learning(GO:0061743) |
0.2 | 2.3 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
0.2 | 0.6 | GO:0006566 | threonine metabolic process(GO:0006566) |
0.2 | 1.0 | GO:0031580 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
0.2 | 0.6 | GO:0002940 | tRNA N2-guanine methylation(GO:0002940) |
0.2 | 3.6 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
0.2 | 0.8 | GO:0090365 | regulation of mRNA modification(GO:0090365) |
0.2 | 0.6 | GO:0038044 | negative regulation of receptor biosynthetic process(GO:0010871) transforming growth factor-beta secretion(GO:0038044) |
0.2 | 1.2 | GO:0006570 | tyrosine metabolic process(GO:0006570) |
0.2 | 0.6 | GO:0006592 | ornithine biosynthetic process(GO:0006592) |
0.2 | 1.5 | GO:0016576 | histone dephosphorylation(GO:0016576) |
0.2 | 0.5 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
0.2 | 0.7 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
0.2 | 0.6 | GO:0015744 | succinate transport(GO:0015744) |
0.2 | 0.8 | GO:2000987 | positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987) |
0.1 | 0.7 | GO:1904659 | glucose transmembrane transport(GO:1904659) |
0.1 | 0.5 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
0.1 | 5.5 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
0.1 | 0.4 | GO:0021577 | hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) |
0.1 | 0.5 | GO:0010808 | positive regulation of synaptic vesicle priming(GO:0010808) |
0.1 | 0.5 | GO:1904504 | regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504) |
0.1 | 2.0 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
0.1 | 0.4 | GO:1904760 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) |
0.1 | 1.1 | GO:0071493 | cellular response to UV-B(GO:0071493) |
0.1 | 0.3 | GO:1902071 | regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071) |
0.1 | 0.3 | GO:0046544 | regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544) |
0.1 | 0.3 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
0.1 | 0.7 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
0.1 | 0.6 | GO:0070827 | chromatin maintenance(GO:0070827) |
0.1 | 0.3 | GO:1901675 | negative regulation of histone H3-K27 acetylation(GO:1901675) |
0.1 | 0.5 | GO:0072717 | cellular response to actinomycin D(GO:0072717) |
0.1 | 0.3 | GO:0097278 | transforming growth factor beta activation(GO:0036363) complement-dependent cytotoxicity(GO:0097278) |
0.1 | 1.7 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
0.1 | 0.3 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
0.1 | 0.3 | GO:0045006 | DNA deamination(GO:0045006) |
0.1 | 0.4 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
0.1 | 2.8 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
0.1 | 1.0 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
0.1 | 0.4 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
0.1 | 0.5 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
0.1 | 0.3 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
0.1 | 0.8 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.1 | 0.8 | GO:2001269 | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269) |
0.1 | 0.4 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
0.1 | 0.4 | GO:0051387 | negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) |
0.1 | 0.3 | GO:0006933 | negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933) |
0.1 | 2.7 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
0.1 | 1.0 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.1 | 0.6 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.1 | 0.1 | GO:0072488 | ammonium transmembrane transport(GO:0072488) |
0.1 | 0.2 | GO:0000389 | generation of catalytic spliceosome for second transesterification step(GO:0000350) mRNA 3'-splice site recognition(GO:0000389) |
0.1 | 1.0 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
0.1 | 0.1 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
0.1 | 0.5 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
0.1 | 0.6 | GO:0019243 | methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727) |
0.1 | 1.1 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
0.1 | 0.4 | GO:0070092 | regulation of glucagon secretion(GO:0070092) |
0.1 | 0.4 | GO:0010908 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) |
0.1 | 2.5 | GO:0000578 | embryonic axis specification(GO:0000578) |
0.1 | 0.2 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
0.1 | 1.3 | GO:0007530 | sex determination(GO:0007530) |
0.1 | 0.5 | GO:0098700 | neurotransmitter loading into synaptic vesicle(GO:0098700) |
0.1 | 2.6 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
0.1 | 0.9 | GO:0051451 | myoblast migration(GO:0051451) |
0.1 | 0.9 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
0.1 | 0.2 | GO:0021506 | anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995) |
0.1 | 1.9 | GO:0071385 | cellular response to glucocorticoid stimulus(GO:0071385) |
0.1 | 0.3 | GO:0018158 | protein oxidation(GO:0018158) |
0.1 | 0.5 | GO:0009162 | deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
0.1 | 0.3 | GO:0040031 | snRNA modification(GO:0040031) |
0.1 | 0.4 | GO:0045002 | double-strand break repair via single-strand annealing(GO:0045002) |
0.1 | 0.4 | GO:0046498 | S-adenosylhomocysteine metabolic process(GO:0046498) |
0.1 | 1.0 | GO:0007019 | microtubule depolymerization(GO:0007019) |
0.1 | 0.7 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
0.1 | 0.7 | GO:0006490 | oligosaccharide-lipid intermediate biosynthetic process(GO:0006490) |
0.1 | 0.3 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
0.0 | 0.1 | GO:1904431 | positive regulation of t-circle formation(GO:1904431) |
0.0 | 0.1 | GO:0009814 | defense response, incompatible interaction(GO:0009814) |
0.0 | 0.1 | GO:0070203 | regulation of establishment of protein localization to telomere(GO:0070203) |
0.0 | 0.6 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
0.0 | 0.2 | GO:0006421 | asparaginyl-tRNA aminoacylation(GO:0006421) |
0.0 | 0.3 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
0.0 | 2.3 | GO:0042491 | auditory receptor cell differentiation(GO:0042491) |
0.0 | 0.5 | GO:1990173 | protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173) |
0.0 | 0.2 | GO:0015692 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
0.0 | 0.4 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
0.0 | 0.1 | GO:2000314 | negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
0.0 | 0.1 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
0.0 | 1.0 | GO:0006907 | pinocytosis(GO:0006907) |
0.0 | 0.3 | GO:0008343 | adult feeding behavior(GO:0008343) positive regulation of feeding behavior(GO:2000253) |
0.0 | 0.7 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
0.0 | 0.1 | GO:0001803 | antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) |
0.0 | 0.4 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
0.0 | 0.2 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
0.0 | 0.1 | GO:0016561 | protein import into peroxisome matrix, translocation(GO:0016561) |
0.0 | 1.4 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
0.0 | 0.1 | GO:0075136 | response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) neutrophil mediated killing of bacterium(GO:0070944) response to host(GO:0075136) |
0.0 | 0.9 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
0.0 | 0.2 | GO:0016584 | nucleosome positioning(GO:0016584) |
0.0 | 0.8 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
0.0 | 0.1 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
0.0 | 1.0 | GO:0034508 | centromere complex assembly(GO:0034508) |
0.0 | 0.2 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
0.0 | 0.9 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 0.2 | GO:2001168 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
0.0 | 0.4 | GO:0003334 | keratinocyte development(GO:0003334) |
0.0 | 0.2 | GO:0035720 | intraciliary anterograde transport(GO:0035720) |
0.0 | 0.2 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
0.0 | 0.4 | GO:0060712 | spongiotrophoblast layer development(GO:0060712) |
0.0 | 0.1 | GO:0006776 | vitamin A metabolic process(GO:0006776) positive regulation of skeletal muscle tissue regeneration(GO:0043415) |
0.0 | 0.1 | GO:0010920 | negative regulation of inositol phosphate biosynthetic process(GO:0010920) |
0.0 | 1.7 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
0.0 | 0.1 | GO:0030647 | polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598) |
0.0 | 0.7 | GO:0072337 | modified amino acid transport(GO:0072337) |
0.0 | 0.5 | GO:0090201 | negative regulation of release of cytochrome c from mitochondria(GO:0090201) |
0.0 | 0.2 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
0.0 | 0.1 | GO:0002188 | translation reinitiation(GO:0002188) |
0.0 | 0.8 | GO:0051560 | mitochondrial calcium ion homeostasis(GO:0051560) |
0.0 | 0.4 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.0 | 0.8 | GO:0009060 | aerobic respiration(GO:0009060) |
0.0 | 0.3 | GO:0009048 | dosage compensation by inactivation of X chromosome(GO:0009048) |
0.0 | 1.3 | GO:0051693 | actin filament capping(GO:0051693) |
0.0 | 0.2 | GO:0050856 | regulation of T cell receptor signaling pathway(GO:0050856) negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860) |
0.0 | 0.4 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
0.0 | 0.1 | GO:0038145 | macrophage colony-stimulating factor signaling pathway(GO:0038145) |
0.0 | 0.2 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
0.0 | 0.5 | GO:0050687 | negative regulation of defense response to virus(GO:0050687) |
0.0 | 0.3 | GO:0001675 | acrosome assembly(GO:0001675) |
0.0 | 0.1 | GO:0036324 | negative regulation of toll-like receptor 4 signaling pathway(GO:0034144) vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) |
0.0 | 0.1 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
0.0 | 0.7 | GO:0010842 | retina layer formation(GO:0010842) |
0.0 | 0.3 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
0.0 | 0.3 | GO:0030497 | fatty acid elongation(GO:0030497) |
0.0 | 0.4 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
0.0 | 0.1 | GO:0002339 | B cell selection(GO:0002339) |
0.0 | 0.5 | GO:0030212 | hyaluronan metabolic process(GO:0030212) |
0.0 | 0.1 | GO:1903630 | regulation of aminoacyl-tRNA ligase activity(GO:1903630) positive regulation of aminoacyl-tRNA ligase activity(GO:1903632) regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
0.0 | 0.2 | GO:0042407 | cristae formation(GO:0042407) |
0.0 | 0.3 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
0.0 | 0.1 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
0.0 | 0.2 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
0.0 | 2.1 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
0.0 | 0.7 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
0.0 | 0.2 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
0.0 | 0.1 | GO:0032289 | central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912) |
0.0 | 0.8 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
0.0 | 0.1 | GO:0070650 | actin filament bundle distribution(GO:0070650) |
0.0 | 0.5 | GO:0003016 | respiratory system process(GO:0003016) |
0.0 | 0.1 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
0.0 | 1.1 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
0.0 | 0.4 | GO:0090199 | regulation of release of cytochrome c from mitochondria(GO:0090199) |
0.0 | 0.1 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
0.0 | 0.2 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
0.0 | 0.1 | GO:0070475 | rRNA base methylation(GO:0070475) |
0.0 | 0.3 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
0.0 | 0.2 | GO:0007094 | mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173) |
0.0 | 0.3 | GO:0006910 | phagocytosis, recognition(GO:0006910) complement activation, classical pathway(GO:0006958) |
0.0 | 0.1 | GO:0001880 | Mullerian duct regression(GO:0001880) |
0.0 | 0.1 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
0.0 | 0.7 | GO:0032543 | mitochondrial translation(GO:0032543) |
0.0 | 0.1 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
0.0 | 0.1 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
0.0 | 0.3 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
0.0 | 0.8 | GO:0042475 | odontogenesis of dentin-containing tooth(GO:0042475) |
0.0 | 0.7 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
0.0 | 0.1 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
0.0 | 0.1 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
0.0 | 0.1 | GO:0090527 | actin filament reorganization(GO:0090527) |
0.0 | 0.3 | GO:0030488 | tRNA methylation(GO:0030488) |
0.0 | 0.1 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
0.0 | 0.2 | GO:0072673 | megakaryocyte development(GO:0035855) lamellipodium morphogenesis(GO:0072673) |
0.0 | 0.0 | GO:0016056 | rhodopsin mediated signaling pathway(GO:0016056) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 2.1 | GO:0008623 | CHRAC(GO:0008623) |
0.5 | 2.0 | GO:0002111 | BRCA2-BRAF35 complex(GO:0002111) |
0.5 | 1.5 | GO:0070557 | PCNA-p21 complex(GO:0070557) |
0.5 | 2.3 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
0.3 | 0.8 | GO:0071914 | prominosome(GO:0071914) |
0.2 | 0.6 | GO:0034684 | integrin alphav-beta5 complex(GO:0034684) |
0.2 | 0.8 | GO:0032280 | symmetric synapse(GO:0032280) |
0.2 | 0.8 | GO:0060187 | cell pole(GO:0060187) |
0.2 | 0.9 | GO:0031262 | Ndc80 complex(GO:0031262) |
0.1 | 0.7 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
0.1 | 1.5 | GO:0098643 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.1 | 0.4 | GO:0001651 | dense fibrillar component(GO:0001651) |
0.1 | 1.3 | GO:0032797 | SMN complex(GO:0032797) |
0.1 | 0.6 | GO:0001674 | female germ cell nucleus(GO:0001674) |
0.1 | 0.9 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
0.1 | 0.5 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
0.1 | 7.1 | GO:0070469 | respiratory chain(GO:0070469) |
0.1 | 0.5 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
0.1 | 0.7 | GO:0042382 | paraspeckles(GO:0042382) |
0.1 | 0.3 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
0.1 | 0.5 | GO:0044305 | calyx of Held(GO:0044305) |
0.1 | 0.7 | GO:0072687 | meiotic spindle(GO:0072687) |
0.1 | 0.4 | GO:0070876 | SOSS complex(GO:0070876) |
0.1 | 0.5 | GO:0097422 | tubular endosome(GO:0097422) |
0.1 | 2.1 | GO:0000788 | nuclear nucleosome(GO:0000788) |
0.1 | 0.4 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
0.1 | 0.4 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
0.1 | 0.9 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.1 | 0.3 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
0.1 | 0.3 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
0.1 | 0.6 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
0.1 | 0.7 | GO:0016600 | flotillin complex(GO:0016600) |
0.1 | 0.5 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
0.1 | 0.8 | GO:0042555 | MCM complex(GO:0042555) |
0.0 | 0.4 | GO:0030478 | actin cap(GO:0030478) |
0.0 | 0.1 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
0.0 | 0.5 | GO:0000243 | commitment complex(GO:0000243) |
0.0 | 0.2 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
0.0 | 1.2 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.0 | 0.3 | GO:0005796 | Golgi lumen(GO:0005796) |
0.0 | 0.2 | GO:0070826 | paraferritin complex(GO:0070826) |
0.0 | 3.1 | GO:0005657 | replication fork(GO:0005657) |
0.0 | 0.5 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.0 | 0.5 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
0.0 | 0.8 | GO:0005682 | U5 snRNP(GO:0005682) |
0.0 | 0.2 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
0.0 | 0.7 | GO:0033655 | host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655) |
0.0 | 0.8 | GO:0045120 | pronucleus(GO:0045120) |
0.0 | 0.3 | GO:0045261 | mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261) |
0.0 | 0.3 | GO:0097413 | Lewy body(GO:0097413) |
0.0 | 0.1 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
0.0 | 0.2 | GO:0033503 | HULC complex(GO:0033503) |
0.0 | 0.3 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
0.0 | 0.1 | GO:1990032 | parallel fiber(GO:1990032) |
0.0 | 0.1 | GO:0034657 | GID complex(GO:0034657) |
0.0 | 0.2 | GO:0042613 | MHC class II protein complex(GO:0042613) |
0.0 | 0.1 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
0.0 | 0.7 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.3 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
0.0 | 0.3 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
0.0 | 1.4 | GO:0016459 | myosin complex(GO:0016459) |
0.0 | 0.1 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
0.0 | 0.6 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
0.0 | 0.2 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.0 | 0.4 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
0.0 | 0.1 | GO:0005744 | mitochondrial inner membrane presequence translocase complex(GO:0005744) |
0.0 | 0.4 | GO:0033276 | transcription factor TFTC complex(GO:0033276) |
0.0 | 1.5 | GO:0072686 | mitotic spindle(GO:0072686) |
0.0 | 0.1 | GO:0070187 | telosome(GO:0070187) |
0.0 | 0.1 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
0.0 | 0.5 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.0 | 0.1 | GO:0042583 | chromaffin granule(GO:0042583) |
0.0 | 2.2 | GO:0000792 | heterochromatin(GO:0000792) |
0.0 | 0.2 | GO:0031209 | SCAR complex(GO:0031209) |
0.0 | 0.2 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 1.2 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.0 | 1.3 | GO:0000784 | nuclear chromosome, telomeric region(GO:0000784) |
0.0 | 1.0 | GO:0005871 | kinesin complex(GO:0005871) |
0.0 | 0.3 | GO:0016580 | Sin3 complex(GO:0016580) |
0.0 | 0.5 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 0.1 | GO:0071014 | post-mRNA release spliceosomal complex(GO:0071014) |
0.0 | 0.2 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.0 | 0.2 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
0.0 | 0.2 | GO:0000502 | proteasome complex(GO:0000502) |
0.0 | 6.1 | GO:0005925 | focal adhesion(GO:0005925) |
0.0 | 0.5 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.0 | 4.0 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 0.2 | GO:0097542 | dendrite terminus(GO:0044292) ciliary tip(GO:0097542) |
0.0 | 0.2 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
0.0 | 0.1 | GO:0005688 | U6 snRNP(GO:0005688) |
0.0 | 0.6 | GO:0000794 | condensed nuclear chromosome(GO:0000794) |
0.0 | 0.1 | GO:0042101 | T cell receptor complex(GO:0042101) |
0.0 | 0.4 | GO:0032993 | protein-DNA complex(GO:0032993) |
0.0 | 0.1 | GO:0030427 | site of polarized growth(GO:0030427) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.5 | GO:0019912 | cyclin-dependent protein kinase activating kinase activity(GO:0019912) |
0.5 | 1.4 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
0.3 | 1.2 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
0.2 | 0.6 | GO:0015140 | malate transmembrane transporter activity(GO:0015140) |
0.2 | 0.6 | GO:0017084 | glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202) |
0.2 | 5.6 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.2 | 0.6 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
0.2 | 4.1 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.2 | 1.0 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
0.2 | 0.5 | GO:0001565 | phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566) |
0.1 | 0.6 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
0.1 | 0.4 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
0.1 | 0.8 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
0.1 | 0.5 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.1 | 1.0 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
0.1 | 0.6 | GO:0004809 | tRNA (guanine-N2-)-methyltransferase activity(GO:0004809) |
0.1 | 0.4 | GO:0008534 | oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534) |
0.1 | 0.6 | GO:0038132 | neuregulin binding(GO:0038132) |
0.1 | 1.5 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
0.1 | 0.3 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
0.1 | 0.7 | GO:0050694 | galactose 3-O-sulfotransferase activity(GO:0050694) |
0.1 | 0.8 | GO:0001515 | opioid peptide activity(GO:0001515) |
0.1 | 0.3 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
0.1 | 0.3 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
0.1 | 1.5 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
0.1 | 2.4 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
0.1 | 1.8 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.1 | 0.5 | GO:0034235 | GPI anchor binding(GO:0034235) |
0.1 | 1.5 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.1 | 0.9 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
0.1 | 0.3 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924) |
0.1 | 1.1 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.1 | 0.8 | GO:1990446 | U1 snRNP binding(GO:1990446) |
0.1 | 0.3 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
0.1 | 0.6 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.1 | 0.6 | GO:1990948 | ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948) |
0.1 | 0.6 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
0.1 | 0.5 | GO:0070728 | leucine binding(GO:0070728) |
0.1 | 0.8 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
0.1 | 0.8 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
0.1 | 0.5 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.1 | 0.5 | GO:0034452 | dynactin binding(GO:0034452) |
0.1 | 0.7 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
0.1 | 0.4 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
0.1 | 0.5 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
0.1 | 0.4 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
0.1 | 0.7 | GO:1990405 | protein antigen binding(GO:1990405) |
0.1 | 0.4 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.1 | 0.3 | GO:0043532 | angiostatin binding(GO:0043532) |
0.1 | 0.4 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
0.1 | 1.6 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.1 | 0.2 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
0.1 | 0.3 | GO:0008172 | S-methyltransferase activity(GO:0008172) |
0.1 | 0.8 | GO:0015149 | hexose transmembrane transporter activity(GO:0015149) |
0.0 | 0.7 | GO:0005537 | mannose binding(GO:0005537) |
0.0 | 0.2 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
0.0 | 0.9 | GO:0017049 | GTP-Rho binding(GO:0017049) |
0.0 | 0.5 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.2 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
0.0 | 1.6 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
0.0 | 0.2 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
0.0 | 0.9 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 1.4 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.0 | 1.7 | GO:0042169 | SH2 domain binding(GO:0042169) |
0.0 | 1.9 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.1 | GO:0016501 | prostacyclin receptor activity(GO:0016501) |
0.0 | 0.4 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
0.0 | 0.4 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
0.0 | 0.2 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
0.0 | 0.2 | GO:0031490 | chromatin DNA binding(GO:0031490) |
0.0 | 1.2 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
0.0 | 0.8 | GO:0043395 | heparan sulfate proteoglycan binding(GO:0043395) |
0.0 | 0.1 | GO:0008988 | rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) U6 snRNA 3'-end binding(GO:0030629) |
0.0 | 0.3 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
0.0 | 0.1 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
0.0 | 0.3 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.0 | 0.8 | GO:0042805 | actinin binding(GO:0042805) |
0.0 | 0.3 | GO:0016427 | tRNA (cytosine) methyltransferase activity(GO:0016427) |
0.0 | 0.3 | GO:0050693 | LBD domain binding(GO:0050693) |
0.0 | 0.7 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.0 | 2.8 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.0 | 0.7 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 0.4 | GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) |
0.0 | 0.3 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
0.0 | 0.4 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
0.0 | 0.1 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
0.0 | 0.1 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
0.0 | 0.2 | GO:0071253 | connexin binding(GO:0071253) |
0.0 | 0.2 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
0.0 | 1.3 | GO:0030507 | spectrin binding(GO:0030507) |
0.0 | 0.1 | GO:0019770 | IgG receptor activity(GO:0019770) |
0.0 | 0.1 | GO:0001729 | ceramide kinase activity(GO:0001729) |
0.0 | 0.5 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
0.0 | 0.3 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
0.0 | 0.4 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
0.0 | 0.1 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) |
0.0 | 0.3 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.0 | 0.8 | GO:0008146 | sulfotransferase activity(GO:0008146) |
0.0 | 0.9 | GO:0015485 | cholesterol binding(GO:0015485) |
0.0 | 0.1 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
0.0 | 0.1 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
0.0 | 0.2 | GO:0005522 | profilin binding(GO:0005522) |
0.0 | 0.8 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
0.0 | 0.2 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.0 | 0.1 | GO:0016655 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655) |
0.0 | 0.4 | GO:0051787 | misfolded protein binding(GO:0051787) |
0.0 | 0.1 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
0.0 | 0.0 | GO:0046592 | polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901) |
0.0 | 0.9 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
0.0 | 0.1 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
0.0 | 0.1 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
0.0 | 1.8 | GO:0003774 | motor activity(GO:0003774) |
0.0 | 0.4 | GO:0043621 | protein self-association(GO:0043621) |
0.0 | 0.1 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
0.0 | 0.7 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
0.0 | 0.8 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
0.0 | 0.2 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
0.0 | 0.3 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.0 | 0.3 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.4 | GO:0005516 | calmodulin binding(GO:0005516) |
0.0 | 0.1 | GO:0016421 | CoA carboxylase activity(GO:0016421) |
0.0 | 0.2 | GO:0045125 | bioactive lipid receptor activity(GO:0045125) |
0.0 | 0.1 | GO:0022842 | leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 2.9 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.1 | 0.7 | PID_TCPTP_PATHWAY | Signaling events mediated by TCPTP |
0.0 | 0.6 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.0 | 2.8 | PID_INTEGRIN1_PATHWAY | Beta1 integrin cell surface interactions |
0.0 | 0.9 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 1.8 | PID_PLK1_PATHWAY | PLK1 signaling events |
0.0 | 2.0 | PID_MYC_REPRESS_PATHWAY | Validated targets of C-MYC transcriptional repression |
0.0 | 0.6 | PID_FANCONI_PATHWAY | Fanconi anemia pathway |
0.0 | 1.3 | PID_NETRIN_PATHWAY | Netrin-mediated signaling events |
0.0 | 0.3 | PID_IL5_PATHWAY | IL5-mediated signaling events |
0.0 | 0.3 | PID_SYNDECAN_3_PATHWAY | Syndecan-3-mediated signaling events |
0.0 | 0.6 | PID_WNT_NONCANONICAL_PATHWAY | Noncanonical Wnt signaling pathway |
0.0 | 0.5 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.0 | 0.5 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
0.0 | 1.0 | ST_G_ALPHA_I_PATHWAY | G alpha i Pathway |
0.0 | 0.5 | PID_MAPK_TRK_PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
0.0 | 0.5 | SA_B_CELL_RECEPTOR_COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
0.0 | 0.5 | PID_PTP1B_PATHWAY | Signaling events mediated by PTP1B |
0.0 | 1.0 | PID_AP1_PATHWAY | AP-1 transcription factor network |
0.0 | 0.2 | PID_ALK2_PATHWAY | ALK2 signaling events |
0.0 | 0.2 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
0.0 | 1.0 | PID_BETA_CATENIN_NUC_PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
0.0 | 0.9 | PID_RHOA_REG_PATHWAY | Regulation of RhoA activity |
0.0 | 0.3 | PID_VEGFR1_2_PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
0.0 | 0.2 | PID_HDAC_CLASSII_PATHWAY | Signaling events mediated by HDAC Class II |
0.0 | 0.1 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 0.8 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 0.6 | PID_P53_REGULATION_PATHWAY | p53 pathway |
0.0 | 0.5 | PID_HES_HEY_PATHWAY | Notch-mediated HES/HEY network |
0.0 | 0.2 | PID_HIF2PATHWAY | HIF-2-alpha transcription factor network |
0.0 | 0.5 | PID_RB_1PATHWAY | Regulation of retinoblastoma protein |
0.0 | 0.4 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | E-cadherin signaling in the nascent adherens junction |
0.0 | 0.8 | PID_HDAC_CLASSI_PATHWAY | Signaling events mediated by HDAC Class I |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 0.6 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
0.1 | 0.5 | REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
0.1 | 3.2 | REACTOME_RNA_POL_I_PROMOTER_OPENING | Genes involved in RNA Polymerase I Promoter Opening |
0.1 | 1.5 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
0.1 | 0.6 | REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
0.1 | 1.5 | REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
0.0 | 0.8 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
0.0 | 1.2 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | Genes involved in Sulfur amino acid metabolism |
0.0 | 1.0 | REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
0.0 | 0.4 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
0.0 | 0.6 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
0.0 | 0.5 | REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
0.0 | 1.8 | REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS | Genes involved in O-linked glycosylation of mucins |
0.0 | 0.3 | REACTOME_THE_NLRP3_INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
0.0 | 1.0 | REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
0.0 | 0.8 | REACTOME_HS_GAG_DEGRADATION | Genes involved in HS-GAG degradation |
0.0 | 0.6 | REACTOME_GLUTAMATE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
0.0 | 0.6 | REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
0.0 | 0.6 | REACTOME_PECAM1_INTERACTIONS | Genes involved in PECAM1 interactions |
0.0 | 0.9 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
0.0 | 0.4 | REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
0.0 | 0.7 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
0.0 | 0.3 | REACTOME_PROLACTIN_RECEPTOR_SIGNALING | Genes involved in Prolactin receptor signaling |
0.0 | 0.6 | REACTOME_FORMATION_OF_TUBULIN_FOLDING_INTERMEDIATES_BY_CCT_TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
0.0 | 0.1 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
0.0 | 0.5 | REACTOME_FORMATION_OF_ATP_BY_CHEMIOSMOTIC_COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
0.0 | 0.5 | REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY | Genes involved in Notch-HLH transcription pathway |
0.0 | 1.6 | REACTOME_COLLAGEN_FORMATION | Genes involved in Collagen formation |
0.0 | 0.3 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
0.0 | 0.2 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
0.0 | 0.7 | REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
0.0 | 0.5 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
0.0 | 0.9 | REACTOME_GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
0.0 | 0.3 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
0.0 | 0.8 | REACTOME_METABOLISM_OF_NON_CODING_RNA | Genes involved in Metabolism of non-coding RNA |
0.0 | 1.9 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.0 | 2.0 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
0.0 | 0.9 | REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
0.0 | 0.6 | REACTOME_SMOOTH_MUSCLE_CONTRACTION | Genes involved in Smooth Muscle Contraction |
0.0 | 0.6 | REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
0.0 | 0.4 | REACTOME_ERK_MAPK_TARGETS | Genes involved in ERK/MAPK targets |
0.0 | 0.2 | REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.0 | 0.5 | REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
0.0 | 0.3 | REACTOME_ZINC_TRANSPORTERS | Genes involved in Zinc transporters |
0.0 | 0.5 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
0.0 | 0.6 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | Genes involved in Mitochondrial Protein Import |
0.0 | 0.5 | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
0.0 | 0.9 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | Genes involved in Respiratory electron transport |
0.0 | 1.5 | REACTOME_G_ALPHA_I_SIGNALLING_EVENTS | Genes involved in G alpha (i) signalling events |
0.0 | 1.2 | REACTOME_PEPTIDE_CHAIN_ELONGATION | Genes involved in Peptide chain elongation |
0.0 | 0.4 | REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
0.0 | 0.8 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | Genes involved in NRAGE signals death through JNK |
0.0 | 0.4 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
0.0 | 2.4 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |