Motif ID: Egr4

Z-value: 0.796


Transcription factors associated with Egr4:

Gene SymbolEntrez IDGene Name
Egr4 ENSMUSG00000071341.3 Egr4



Activity profile for motif Egr4.

activity profile for motif Egr4


Sorted Z-values histogram for motif Egr4

Sorted Z-values for motif Egr4



Network of associatons between targets according to the STRING database.



First level regulatory network of Egr4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_70851189 4.518 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr19_+_25505618 2.704 ENSMUST00000025755.4
Dmrt1
doublesex and mab-3 related transcription factor 1
chr13_+_48261427 2.599 ENSMUST00000021810.1
Id4
inhibitor of DNA binding 4
chr2_-_102186322 2.270 ENSMUST00000111222.1
ENSMUST00000058790.5
Ldlrad3

low density lipoprotein receptor class A domain containing 3

chr12_+_17690793 1.735 ENSMUST00000071858.3
Hpcal1
hippocalcin-like 1
chr5_-_149051604 1.566 ENSMUST00000093196.4
Hmgb1
high mobility group box 1
chr17_-_31658729 1.460 ENSMUST00000166526.1
ENSMUST00000014684.4
U2af1

U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1

chr3_+_135438722 1.416 ENSMUST00000166033.1
Ube2d3
ubiquitin-conjugating enzyme E2D 3
chr18_+_35829798 1.302 ENSMUST00000060722.6
Cxxc5
CXXC finger 5
chr9_+_65630552 1.221 ENSMUST00000055844.8
Rbpms2
RNA binding protein with multiple splicing 2
chr8_-_92355764 1.147 ENSMUST00000180102.1
ENSMUST00000179421.1
ENSMUST00000179222.1
ENSMUST00000179029.1
4933436C20Rik



RIKEN cDNA 4933436C20 gene



chr11_-_87987528 1.144 ENSMUST00000020775.2
Dynll2
dynein light chain LC8-type 2
chr16_+_93883895 1.097 ENSMUST00000023666.4
ENSMUST00000117099.1
ENSMUST00000142316.1
Chaf1b


chromatin assembly factor 1, subunit B (p60)


chr17_-_23677432 1.065 ENSMUST00000167059.1
ENSMUST00000024698.8
Tnfrsf12a

tumor necrosis factor receptor superfamily, member 12a

chr10_+_19591949 1.060 ENSMUST00000020188.6
Ifngr1
interferon gamma receptor 1
chr6_-_85451248 0.992 ENSMUST00000113770.1
ENSMUST00000032080.2
Pradc1

protease-associated domain containing 1

chr16_-_36071515 0.980 ENSMUST00000004057.7
Fam162a
family with sequence similarity 162, member A
chr4_+_128883549 0.955 ENSMUST00000035667.8
Trim62
tripartite motif-containing 62
chr16_+_64851991 0.943 ENSMUST00000067744.7
Cggbp1
CGG triplet repeat binding protein 1
chr16_+_36071624 0.931 ENSMUST00000164916.1
ENSMUST00000163352.1
Ccdc58

coiled-coil domain containing 58

chr10_-_81350389 0.878 ENSMUST00000020454.4
ENSMUST00000105324.2
ENSMUST00000154609.2
ENSMUST00000105323.1
Hmg20b



high mobility group 20B



chr6_+_4747306 0.859 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
Peg10


paternally expressed 10


chr10_-_81350191 0.854 ENSMUST00000122993.1
Hmg20b
high mobility group 20B
chrX_-_48513518 0.834 ENSMUST00000114945.2
ENSMUST00000037349.7
Aifm1

apoptosis-inducing factor, mitochondrion-associated 1

chr15_+_26309039 0.824 ENSMUST00000140840.1
ENSMUST00000152841.1
March11

membrane-associated ring finger (C3HC4) 11

chr10_-_81350305 0.794 ENSMUST00000167481.1
Hmg20b
high mobility group 20B
chr19_-_8786272 0.787 ENSMUST00000176610.1
ENSMUST00000177056.1
Taf6l

TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor

chr3_+_144570687 0.772 ENSMUST00000106211.1
Sep15
selenoprotein
chr13_-_55513427 0.760 ENSMUST00000069929.6
ENSMUST00000069968.6
ENSMUST00000131306.1
ENSMUST00000046246.6
Pdlim7



PDZ and LIM domain 7



chr11_-_102407899 0.750 ENSMUST00000124755.1
Slc25a39
solute carrier family 25, member 39
chr14_+_75845093 0.743 ENSMUST00000110894.2
Tpt1
tumor protein, translationally-controlled 1
chr19_-_8786245 0.737 ENSMUST00000177216.1
Taf6l
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr11_-_102407455 0.731 ENSMUST00000107098.1
ENSMUST00000018821.2
Slc25a39

solute carrier family 25, member 39

chr9_+_118926453 0.726 ENSMUST00000073109.5
Ctdspl
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr8_-_92356103 0.724 ENSMUST00000034183.3
4933436C20Rik
RIKEN cDNA 4933436C20 gene
chr15_-_36608959 0.717 ENSMUST00000001809.8
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr10_+_128232065 0.716 ENSMUST00000055539.4
ENSMUST00000105244.1
ENSMUST00000105243.2
ENSMUST00000125289.1
ENSMUST00000105242.1
Timeless




timeless circadian clock 1




chr2_+_92184106 0.693 ENSMUST00000111294.1
ENSMUST00000111293.2
ENSMUST00000162146.1
ENSMUST00000111292.1
ENSMUST00000162497.1
Phf21a




PHD finger protein 21A




chr1_-_52500679 0.690 ENSMUST00000069792.7
Nab1
Ngfi-A binding protein 1
chr9_+_108306205 0.685 ENSMUST00000007959.8
Rhoa
ras homolog gene family, member A
chr2_-_148045891 0.676 ENSMUST00000109964.1
Foxa2
forkhead box A2
chr7_+_35119285 0.652 ENSMUST00000042985.9
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr15_+_58141397 0.638 ENSMUST00000067563.7
Wdyhv1
WDYHV motif containing 1
chr1_-_97661668 0.623 ENSMUST00000153115.1
ENSMUST00000142234.1
D1Ertd622e

DNA segment, Chr 1, ERATO Doi 622, expressed

chr11_-_102407315 0.614 ENSMUST00000149777.1
ENSMUST00000154001.1
Slc25a39

solute carrier family 25, member 39

chrX_+_36195968 0.614 ENSMUST00000115256.1
Zcchc12
zinc finger, CCHC domain containing 12
chrX_-_153037549 0.563 ENSMUST00000051484.3
Mageh1
melanoma antigen, family H, 1
chr19_-_8786408 0.534 ENSMUST00000176496.1
Taf6l
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr2_-_9883993 0.529 ENSMUST00000114915.2
9230102O04Rik
RIKEN cDNA 9230102O04 gene
chrX_+_36195950 0.514 ENSMUST00000115257.1
Zcchc12
zinc finger, CCHC domain containing 12
chr12_+_76370266 0.512 ENSMUST00000042779.3
Zbtb1
zinc finger and BTB domain containing 1
chr7_-_19404082 0.501 ENSMUST00000108458.3
Klc3
kinesin light chain 3
chr2_+_32535315 0.491 ENSMUST00000133512.1
ENSMUST00000048375.5
Fam102a

family with sequence similarity 102, member A

chrX_+_7762652 0.490 ENSMUST00000077680.3
ENSMUST00000079542.6
ENSMUST00000115679.1
ENSMUST00000137467.1
Tfe3



transcription factor E3



chr14_-_54926784 0.488 ENSMUST00000022813.6
Efs
embryonal Fyn-associated substrate
chr2_+_180589245 0.479 ENSMUST00000029087.3
Ogfr
opioid growth factor receptor
chr11_+_114851507 0.470 ENSMUST00000177952.1
Gprc5c
G protein-coupled receptor, family C, group 5, member C
chr13_+_55445301 0.463 ENSMUST00000001115.8
ENSMUST00000099482.3
Grk6

G protein-coupled receptor kinase 6

chr19_+_6363896 0.460 ENSMUST00000113487.1
Sf1
splicing factor 1
chr4_+_99955715 0.457 ENSMUST00000102783.4
Pgm2
phosphoglucomutase 2
chr17_+_24470393 0.452 ENSMUST00000053024.6
Pgp
phosphoglycolate phosphatase
chr17_+_26138661 0.449 ENSMUST00000074370.3
ENSMUST00000118904.2
ENSMUST00000163421.1
Axin1


axin 1


chr11_-_19018956 0.448 ENSMUST00000068264.7
ENSMUST00000144988.1
ENSMUST00000185131.1
Meis1


Meis homeobox 1


chr14_+_79481164 0.437 ENSMUST00000040131.5
Elf1
E74-like factor 1
chrX_+_36195938 0.409 ENSMUST00000048067.3
Zcchc12
zinc finger, CCHC domain containing 12
chrX_+_36195904 0.406 ENSMUST00000115258.2
Zcchc12
zinc finger, CCHC domain containing 12
chr11_+_70000578 0.399 ENSMUST00000019362.8
Dvl2
dishevelled 2, dsh homolog (Drosophila)
chr1_+_167001457 0.369 ENSMUST00000126198.1
Fam78b
family with sequence similarity 78, member B
chr7_+_126759601 0.360 ENSMUST00000050201.4
ENSMUST00000057669.9
Mapk3

mitogen-activated protein kinase 3

chr10_+_78425670 0.338 ENSMUST00000005185.6
Cstb
cystatin B
chr14_-_79481268 0.331 ENSMUST00000022601.5
Wbp4
WW domain binding protein 4
chr4_+_130055010 0.325 ENSMUST00000123617.1
Col16a1
collagen, type XVI, alpha 1
chr19_+_6363719 0.325 ENSMUST00000113489.1
ENSMUST00000113488.1
Sf1

splicing factor 1

chr19_-_21652779 0.305 ENSMUST00000179768.1
ENSMUST00000178523.1
ENSMUST00000038830.3
1110059E24Rik


RIKEN cDNA 1110059E24 gene


chr17_+_69383024 0.297 ENSMUST00000112674.1
Zbtb14
zinc finger and BTB domain containing 14
chr19_+_6363671 0.280 ENSMUST00000131252.1
Sf1
splicing factor 1
chr7_-_63938862 0.276 ENSMUST00000063694.8
Klf13
Kruppel-like factor 13
chr4_-_151996113 0.233 ENSMUST00000055688.9
Phf13
PHD finger protein 13
chr8_+_69088646 0.227 ENSMUST00000006435.7
Atp6v1b2
ATPase, H+ transporting, lysosomal V1 subunit B2
chr11_-_19018714 0.226 ENSMUST00000177417.1
Meis1
Meis homeobox 1
chr8_-_11312731 0.224 ENSMUST00000033898.9
Col4a1
collagen, type IV, alpha 1
chr19_-_5085483 0.209 ENSMUST00000140389.1
ENSMUST00000151413.1
ENSMUST00000077066.7
Tmem151a


transmembrane protein 151A


chr9_+_48985358 0.208 ENSMUST00000047349.6
Usp28
ubiquitin specific peptidase 28
chrX_-_143393893 0.207 ENSMUST00000166406.2
Chrdl1
chordin-like 1
chr6_+_85451488 0.194 ENSMUST00000032078.6
Cct7
chaperonin containing Tcp1, subunit 7 (eta)
chrX_+_7842056 0.173 ENSMUST00000115667.3
ENSMUST00000115668.3
ENSMUST00000115665.1
Otud5


OTU domain containing 5


chr11_+_4186789 0.113 ENSMUST00000041042.6
ENSMUST00000180088.1
Tbc1d10a

TBC1 domain family, member 10a

chr11_-_86993682 0.107 ENSMUST00000018571.4
Ypel2
yippee-like 2 (Drosophila)
chr9_+_114688782 0.096 ENSMUST00000047404.6
Dync1li1
dynein cytoplasmic 1 light intermediate chain 1
chr2_-_119477613 0.076 ENSMUST00000110808.1
ENSMUST00000049920.7
Ino80

INO80 homolog (S. cerevisiae)

chr2_-_48949206 0.057 ENSMUST00000090976.3
ENSMUST00000149679.1
ENSMUST00000028098.4
Orc4


origin recognition complex, subunit 4


chr19_-_21652714 0.039 ENSMUST00000177577.1
1110059E24Rik
RIKEN cDNA 1110059E24 gene
chr10_+_93160824 0.027 ENSMUST00000069965.7
Cdk17
cyclin-dependent kinase 17
chr14_+_56668242 0.015 ENSMUST00000116468.1
Mphosph8
M-phase phosphoprotein 8
chr11_-_51688614 0.014 ENSMUST00000007921.2
0610009B22Rik
RIKEN cDNA 0610009B22 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.5 1.6 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.4 1.9 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.4 2.7 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.4 1.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.3 4.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.7 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.2 0.7 GO:0003100 angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998) regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) regulation of systemic arterial blood pressure by endothelin(GO:0003100) beta selection(GO:0043366) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.2 0.7 GO:0045014 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.2 0.7 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.2 0.5 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.2 0.5 GO:0019401 alditol biosynthetic process(GO:0019401)
0.1 2.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.7 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 1.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 0.5 GO:0002572 pro-T cell differentiation(GO:0002572)
0.1 0.4 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.1 1.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.4 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.1 0.8 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.1 0.6 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.1 1.1 GO:0030238 male sex determination(GO:0030238)
0.1 0.7 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.1 2.1 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 0.4 GO:0000189 MAPK import into nucleus(GO:0000189)
0.1 0.5 GO:0019388 galactose catabolic process(GO:0019388)
0.0 1.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.0 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 1.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.7 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.7 GO:0001967 suckling behavior(GO:0001967)
0.0 1.0 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 2.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.2 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.2 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 0.7 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 1.2 GO:0070613 regulation of protein processing(GO:0070613)
0.0 0.3 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.7 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.9 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 0.8 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.4 1.1 GO:0033186 CAF-1 complex(GO:0033186)
0.2 0.7 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.2 1.5 GO:0089701 U2AF(GO:0089701)
0.1 2.1 GO:0030914 STAGA complex(GO:0030914)
0.1 1.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 0.7 GO:0045298 tubulin complex(GO:0045298)
0.0 0.4 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.6 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.7 GO:0016235 aggresome(GO:0016235)
0.0 0.7 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 2.3 GO:0001726 ruffle(GO:0001726)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.3 0.8 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.3 1.1 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.2 4.5 GO:0070410 co-SMAD binding(GO:0070410)
0.1 1.5 GO:0050733 RS domain binding(GO:0050733)
0.1 0.4 GO:0005118 sevenless binding(GO:0005118)
0.1 2.5 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.5 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.5 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.1 0.7 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 1.9 GO:0032183 SUMO binding(GO:0032183)
0.1 0.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 1.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.7 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 1.4 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 2.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.1 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 2.6 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 4.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 ST_INTERFERON_GAMMA_PATHWAY Interferon gamma pathway.
0.1 2.3 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.1 0.8 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 1.4 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.1 1.1 PID_SMAD2_3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 4.5 PID_AR_PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.8 PID_CERAMIDE_PATHWAY Ceramide signaling pathway
0.0 0.8 PID_BETA_CATENIN_DEG_PATHWAY Degradation of beta catenin
0.0 1.3 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.9 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.6 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.4 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.5 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.9 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.9 REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 1.1 REACTOME_REGULATION_OF_IFNG_SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.5 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.7 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME_CTNNB1_PHOSPHORYLATION_CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 2.9 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.5 REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.1 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.3 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME_INSULIN_RECEPTOR_RECYCLING Genes involved in Insulin receptor recycling