Motif ID: Elf5

Z-value: 0.870


Transcription factors associated with Elf5:

Gene SymbolEntrez IDGene Name
Elf5 ENSMUSG00000027186.8 Elf5



Activity profile for motif Elf5.

activity profile for motif Elf5


Sorted Z-values histogram for motif Elf5

Sorted Z-values for motif Elf5



Network of associatons between targets according to the STRING database.



First level regulatory network of Elf5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 1.908 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr14_-_55671873 1.480 ENSMUST00000163750.1
ENSMUST00000010520.8
 Nedd8

neural precursor cell expressed, developmentally down-regulated gene 8

chr2_+_121456963 1.473 ENSMUST00000126764.1
 Hypk
huntingtin interacting protein K
chr7_-_81345189 1.420 ENSMUST00000080813.4
 Rps17
ribosomal protein S17
chr7_+_105640522 1.316 ENSMUST00000106785.1
ENSMUST00000106786.1
ENSMUST00000106780.1
ENSMUST00000106784.1
 Timm10b



translocase of inner mitochondrial membrane 10B



chr9_+_20644851 1.243 ENSMUST00000161882.1
 Ubl5
ubiquitin-like 5
chr11_+_96034885 1.239 ENSMUST00000006217.3
ENSMUST00000107700.3
 Snf8

SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)

chr7_+_105640448 1.221 ENSMUST00000058333.3
 Timm10b
translocase of inner mitochondrial membrane 10B
chr11_-_53430417 1.212 ENSMUST00000109019.1
 Uqcrq
ubiquinol-cytochrome c reductase, complex III subunit VII
chr12_+_84970897 1.177 ENSMUST00000021669.8
ENSMUST00000171040.1
 Fcf1

FCF1 small subunit (SSU) processome component homolog (S. cerevisiae)

chr5_+_3803160 1.137 ENSMUST00000171023.1
ENSMUST00000080085.4
 Krit1

KRIT1, ankyrin repeat containing

chr19_+_8920358 1.137 ENSMUST00000096243.5
 B3gat3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr6_-_72390659 1.128 ENSMUST00000059983.9
 Vamp8
vesicle-associated membrane protein 8
chr9_+_20644792 1.121 ENSMUST00000162303.1
ENSMUST00000161486.1
 Ubl5

ubiquitin-like 5

chr1_-_133610215 1.111 ENSMUST00000164574.1
ENSMUST00000166291.1
ENSMUST00000164096.1
 Snrpe


small nuclear ribonucleoprotein E


chr5_-_30907692 1.108 ENSMUST00000132034.2
ENSMUST00000132253.2
 Ost4

oligosaccharyltransferase 4 homolog (S. cerevisiae)

chr13_-_98316967 1.106 ENSMUST00000022163.8
ENSMUST00000152704.1
 Btf3

basic transcription factor 3

chr2_+_156144023 1.101 ENSMUST00000088610.4
 Romo1
reactive oxygen species modulator 1
chr1_-_133610253 1.092 ENSMUST00000166915.1
 Snrpe
small nuclear ribonucleoprotein E
chr7_+_126695942 1.090 ENSMUST00000106369.1
 Bola2
bolA-like 2 (E. coli)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 429 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.1 GO:0002181 cytoplasmic translation(GO:0002181)
0.3 5.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 5.4 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 4.2 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 4.2 GO:0006412 translation(GO:0006412)
0.1 3.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 3.3 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.2 2.8 GO:0045116 protein neddylation(GO:0045116)
0.1 2.7 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.3 2.3 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 2.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.7 2.1 GO:0051715 cytolysis in other organism(GO:0051715)
0.3 2.1 GO:0021539 subthalamus development(GO:0021539)
0.0 2.1 GO:0032543 mitochondrial translation(GO:0032543)
0.3 2.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.2 1.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 1.9 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 1.8 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.1 1.7 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 1.7 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 214 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 13.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.2 12.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.4 4.5 GO:0005687 U4 snRNP(GO:0005687)
0.0 4.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 4.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 3.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.7 3.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 3.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 2.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.2 2.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.3 2.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 2.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 2.3 GO:0005838 proteasome regulatory particle(GO:0005838)
0.1 2.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.2 2.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 2.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 2.0 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 2.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 1.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.2 1.8 GO:0016272 prefoldin complex(GO:0016272)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 275 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 23.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 5.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.5 4.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 3.0 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 2.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 2.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.3 2.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 2.2 GO:0031386 protein tag(GO:0031386)
0.1 2.2 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
0.1 2.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 2.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 1.9 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 1.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 1.8 GO:0051082 unfolded protein binding(GO:0051082)
0.2 1.6 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 1.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 1.4 GO:0050733 RS domain binding(GO:0050733)
0.1 1.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)

Gene overrepresentation in C2:CP category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.1 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.2 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.2 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.9 PID_P73PATHWAY p73 transcription factor network
0.1 1.8 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.5 ST_B_CELL_ANTIGEN_RECEPTOR B Cell Antigen Receptor
0.0 1.3 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 1.3 PID_RAC1_PATHWAY RAC1 signaling pathway
0.1 1.2 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.2 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.1 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 0.8 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 0.8 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III
0.1 0.7 PID_AP1_PATHWAY AP-1 transcription factor network
0.0 0.7 PID_HIF1A_PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.7 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 0.6 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 0.6 PID_LYSOPHOSPHOLIPID_PATHWAY LPA receptor mediated events

Gene overrepresentation in C2:CP:REACTOME category:

Showing 1 to 20 of 97 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 13.5 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 10.0 REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.1 10.0 REACTOME_PEPTIDE_CHAIN_ELONGATION Genes involved in Peptide chain elongation
0.1 9.4 REACTOME_RESPIRATORY_ELECTRON_TRANSPORT Genes involved in Respiratory electron transport
0.1 4.8 REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT Genes involved in Mitochondrial Protein Import
0.3 4.0 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 2.4 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 2.3 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 2.1 REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 1.9 REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 1.6 REACTOME_RNA_POL_I_PROMOTER_OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.6 REACTOME_APOPTOTIC_EXECUTION_PHASE Genes involved in Apoptotic execution phase
0.0 1.5 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 1.3 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.2 REACTOME_MRNA_DECAY_BY_3_TO_5_EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.2 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.2 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.2 REACTOME_MRNA_SPLICING Genes involved in mRNA Splicing
0.1 1.0 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.1 1.0 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway